What is the most punctual flight time for Panama City to Santo Domingo flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.

Which airline has the best punctuality record on Panama City to Santo Domingo flights?

Over the past year, Copa Airlines has had the lowest number of delays on this route, with just 5% of flights being delayed.

How often are flights from Panama City to Santo Domingo delayed?

About 5% of weekly flights between Panama City and Santo Domingo have experienced delays in the past year, with the average delay time being 110 minutes.

What day of the week experiences the fewest flight delays on this route?

Thursday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.

How long is the flight from Panama City to Santo Domingo?

Airlines like Copa Airlines fly from Panama City to Santo Domingo in about 2h 32m. The time it takes to get you to your destination is usually consistent. Airlines will cover a distance of 1476 km. Generally, flights for this route are direct.

What are the cheapest airlines flying from Panama City to Santo Domingo round-trip?

Our cheapest airline available from Panama City to Santo Domingo is Avianca. Our recent data shows that you can find tickets from as low as C$ 574 on this airline. An additional option worth looking into is Copa Airlines, starting at C$ 589. Users have found that Avianca is 19% cheaper than the other options available to this destination.

Weekly flight availability from Panama City to Santo Domingo

The most flights from PTY to SDQ are scheduled on a Monday (8 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

In terms of precipitation, rainfall in Santo Domingo ranges from 40.0 - 170.0 mm per month. May is typically the wettest month, when rainfall can reach 170.0 mm. February is typically the driest time to visit Santo Domingo when rainfall is around 40.0 mm.

If weather is an important factor for your trip to Santo Domingo, use this chart to help with planning. For those seeking warmer temperatures, June is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 24.0 C).

What are the most reliable airlines from Panama City to Santo Domingo?

The top 3 most reliable airlines when flying from Panama City to Santo Domingo are KLM (89%), Air France (88%) and Turkish Airlines (88%).

Can I find deals for flights from Panama City to Santo Domingo that include hotel bookings?

Yes. In addition to deals on Panama City to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Panama City to Santo Domingo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santo Domingo.

Can I find deals for business class flights from Panama City to Santo Domingo?

Yes. Cheapflights offers flight deals from Panama City to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 690+ Cheap Flights from Panama City to Santo Domingo

Cheap flight deals from Panama City to Santo Domingo

Enter your travel dates to find the best prices.

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Direct

Last-minute

One-way

Cheapest flights from Panama City to Santo Domingo
Explore the most affordable flight options available from Panama City to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 October 2026.

Sat 19/129:42 a.m. -

Nonstop2h 32m

Sun 20/127:03 p.m. -

Nonstop2h 37m

Deal found 28/10C$ 690

Sun 20/127:26 p.m. -

Nonstop2h 32m

Wed 10/22:19 p.m. -

Nonstop2h 39m

Deal found 27/10C$ 704

Wed 30/1210:41 p.m. -

Nonstop2h 27m

Sat 3/48:40 a.m. -

Nonstop2h 42m

Deal found 23/10C$ 745

Mon 21/126:10 p.m. -

1 stop16h 40m

Fri 25/1212:45 p.m. -

1 stop13h 35m

Deal found 26/10C$ 755

Mon 21/128:15 a.m. -

Nonstop2h 27m

Mon 4/17:05 p.m. -

Nonstop2h 35m

Deal found 27/10C$ 772

Fri 13/1112:44 p.m. -

Nonstop2h 28m

Fri 20/112:20 p.m. -

Nonstop2h 34m

Deal found 24/10C$ 776

Wed 11/1110:41 p.m. -

Nonstop2h 27m

Sat 21/118:55 a.m. -

Nonstop2h 35m

Deal found 24/10C$ 787

Tue 29/127:26 p.m. -

Nonstop2h 32m

Fri 29/12:19 p.m. -

Nonstop2h 39m

Deal found 27/10C$ 805

Fri 13/117:26 p.m. -

Nonstop2h 32m

Tue 17/115:55 a.m. -

Nonstop2h 33m

Deal found 27/10C$ 849

Mon 2/119:42 a.m. -

Nonstop2h 28m

Tue 10/1112:45 p.m. -

Nonstop2h 36m

Deal found 23/10C$ 850

Wed 23/1212:44 p.m. -

Nonstop2h 29m

Sun 3/15:50 a.m. -

Nonstop2h 38m

Deal found 23/10C$ 888

Mon 2/119:42 a.m. -

Nonstop2h 28m

Mon 9/1112:45 p.m. -

Nonstop2h 36m

Deal found 23/10C$ 891

Find flight deals from Panama City to Santo Domingo

Round-trip from	C$ 690
Popular in	July
Cheapest in	January
Average price	C$ 745

Copa Airlines
20/12-15/1
Nonstop
5h 10m total
Panama City to Santo Domingo

Search Deals

Highest demand for flights based on searches. 3% potential increase in price (C$ 35 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 0% potential price decrease (C$ 10 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Tue 8/12

9:42 a.m.-1:14 p.m.

Nonstop2h 32m

Santo Domingo Las Americas

Tue 19/1

12:42 p.m.-2:21 p.m.

Nonstop2h 39m

C$ 690

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Mon 4/1

8:15 a.m.-11:42 a.m.

Nonstop2h 27m

Santo Domingo Las Americas

Fri 29/1

12:06 p.m.-1:45 p.m.

Nonstop2h 39m

C$ 690

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Wed 20/1

7:39 a.m.-11:01 a.m.

Nonstop2h 22m

Santo Domingo Las Americas

Sat 6/2

8:54 a.m.-10:30 a.m.

Nonstop2h 36m

C$ 690

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Sun 10/1

12:44 p.m.-4:08 p.m.

Nonstop2h 24m

Santo Domingo Las Americas

Sun 17/1

5:50 a.m.-7:28 a.m.

Nonstop2h 38m

C$ 690

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Fri 29/1

7:26 p.m.-10:54 p.m.

Nonstop2h 28m

Santo Domingo Las Americas

Tue 9/2

8:54 a.m.-10:30 a.m.

Nonstop2h 36m

C$ 690

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Tue 22/12

7:26 p.m.-10:58 p.m.

Nonstop2h 32m

Santo Domingo Las Americas

Fri 5/2

7:02 p.m.-8:40 p.m.

Nonstop2h 38m

C$ 690

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Mon 23/11

10:41 p.m.-2:08 a.m.

Nonstop2h 27m

Santo Domingo Las Americas

Sat 28/11

12:10 p.m.-1:45 p.m.

Nonstop2h 35m

C$ 690

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Tue 26/1

12:44 p.m.-4:08 p.m.

Nonstop2h 24m

Santo Domingo Las Americas

Sun 21/2

8:54 a.m.-10:30 a.m.

Nonstop2h 36m

C$ 690

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Mon 21/12

10:41 p.m.-2:08 a.m.

Nonstop2h 27m

Santo Domingo Las Americas

Tue 19/1

7:05 p.m.-8:40 p.m.

Nonstop2h 35m

C$ 690

Panama CitySanto Domingo

PTY Panama City Tocumen Intl - SDQ Santo Domingo Las Americas

PTYSDQ

Panama City Tocumen Intl

Tue 15/12

8:15 a.m.-11:42 a.m.

Nonstop2h 27m

Santo Domingo Las Americas

Wed 23/12

8:55 a.m.-10:30 a.m.

Nonstop2h 35m

C$ 690

Flights are sorted by cheapest round-trip flights first.

Deals found on 27/10

Showing 1-10 of 16 resultsSorted by cheapest first

Best time to book a flight from Panama City to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Panama City with our price prediction graph.

PTY-SDQ

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Santo Domingo

Prices

Airlines

Delays

How far ahead should I book a flight from Panama City to Santo Domingo?

The price you pay for your flight from Panama City to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 69 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Santo Domingo?

Currently, January is the cheapest month in which you can book a flight from Panama City to Santo Domingo (average of C$ 644). Flying from Panama City to Santo Domingo in July is currently the most expensive (average of C$ 773). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to SDQ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Santo Domingo as you normally would.

How much does it cost to fly round-trip from Panama City to Santo Domingo?

Airfare is typical for this route at the moment.

Panama City to Santo Domingo flights typically cost between C$ 673 and C$ 769 in December.
The cheapest round-trip price found within the last 5 days was C$ 690 on Copa Airlines (19 Dec-20 Dec).

Reviews of airlines servicing Santo Domingo

Check out reviews from past customers who have flown with Copa Airlines and Avianca from Panama City to Santo Domingo to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Copa Airlines

7.6

Good

1,553 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Copa Airlines

7.6

Good

1,553 reviews

Copa Airlines

7.6

Good

1,553 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Avianca

6.5

Okay

2,550 reviews

Copa Airlines

7.6

Good

1,553 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Maria,Dec 2025

PTY - SLA

Old plain no entertainment , no outlet for cell or computer! And online they said you have all that! Almost 6 hrs looking to the floor..terrible expirencw and I pay a lot of money for it

Related info for your journey

How long is the flight from Panama City to Santo Domingo?
Airlines like Copa Airlines fly from Panama City to Santo Domingo in about 2h 32m. The time it takes to get you to your destination is usually consistent. Airlines will cover a distance of 1476 km. Generally, flights for this route are direct.
What are the cheapest airlines flying from Panama City to Santo Domingo round-trip?
Our cheapest airline available from Panama City to Santo Domingo is Avianca. Our recent data shows that you can find tickets from as low as C$ 574 on this airline. An additional option worth looking into is Copa Airlines, starting at C$ 589. Users have found that Avianca is 19% cheaper than the other options available to this destination.
What are the most reliable airlines from Panama City to Santo Domingo?
The top 3 most reliable airlines when flying from Panama City to Santo Domingo are KLM (89%), Air France (88%) and Turkish Airlines (88%).
Can I find deals for flights from Panama City to Santo Domingo that include hotel bookings?
Yes. In addition to deals on Panama City to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Panama City to Santo Domingo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Santo Domingo.
Can I find deals for business class flights from Panama City to Santo Domingo?
Yes. Cheapflights offers flight deals from Panama City to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Panama City to Santo Domingo?
Currently, January is the cheapest month in which you can book a flight from Panama City to Santo Domingo (average of C$ 644). Flying from Panama City to Santo Domingo in July is currently the most expensive (average of C$ 773). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Complete your trip

Direct flights to Dominican Republic

Flights by cabin class

Other flight options

Other flights from Panama City

Popular flights

Santo Domingo flight routes

Complete your trip

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Santiago de los Caballeros car rentals

Top 2 airlines flying from Panama City to Santo Domingo

Airline	Cheapest	Average	Flexibility	On-time
Avianca	CheapestC$ 574	AverageC$ 634	FlexibilityNo cancel fee	On-time71%	Search Avianca flights
Copa Airlines	CheapestC$ 589	AverageC$ 664	FlexibilityNo cancel fee	On-time70%	Search Copa Airlines flights

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How does Cheapflights help users find flights from Panama City to Santo Domingo?

When you search for this flight from Panama City to Santo Domingo, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Santo Domingo?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama City to Santo Domingo.

Can Cheapflights find flights from Panama City to Santo Domingo with no change fees?

Certainly. Search results for flights to Santo Domingo from Panama City shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Panama City to Santo Domingo become cheaper?

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Cheap flights from Panama City to Santo Domingo from C$ 690

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Panama City to Santo Domingo

Cheapest flights from Panama City to Santo DomingoExplore the most affordable flight options available from Panama City to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 October 2026.

Explore the most affordable flight options available from Panama City to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 October 2026.

Best flights from Panama City to Santo DomingoDiscover carefully curated flight deals from Panama City to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 28 October 2026.

Discover carefully curated flight deals from Panama City to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 28 October 2026.

Direct flights from Panama City to Santo DomingoExplore direct flight options from Panama City to Santo Domingo based on user searches, and compare prices and availability for your desired travel dates. Data last updated 28 October 2026.

Explore direct flight options from Panama City to Santo Domingo based on user searches, and compare prices and availability for your desired travel dates. Data last updated 28 October 2026.

Last-minute flights from Panama City to Santo DomingoDiscover last-minute flight deals from Panama City to Santo Domingo. Data last updated 28 October 2026 and is based on user searches.

Discover last-minute flight deals from Panama City to Santo Domingo. Data last updated 28 October 2026 and is based on user searches.

One-way flights from Panama City to Santo DomingoSearch for one-way flight options from Panama City to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated 28 October 2026.

Search for one-way flight options from Panama City to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated 28 October 2026.

Find flight deals from Panama City to Santo Domingo

Round-trip from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Panama City to Santo Domingo that are best for you.

Best time to book a flight from Panama City to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Panama City with our price prediction graph.

Cheapflights Insights

How far ahead should I book a flight from Panama City to Santo Domingo?

The price you pay for your flight from Panama City to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 69 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Panama City to Santo Domingo?

What is the cheapest time of day to fly from PTY to SDQ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Santo Domingo as you normally would.

How much does it cost to fly round-trip from Panama City to Santo Domingo?

Airfare is typical for this route at the moment.

Panama City to Santo Domingo flights typically cost between C$ 673 and C$ 769 in December.The cheapest round-trip price found within the last 5 days was C$ 690 on Copa Airlines (19 Dec-20 Dec).

Weekly flight availability from Panama City to Santo Domingo

The most flights from PTY to SDQ are scheduled on a Monday (8 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (1 on average).

How often are flights from Panama City to Santo Domingo delayed?

About 5% of weekly flights between Panama City and Santo Domingo have experienced delays in the past year, with the average delay time being 110 minutes.

What is the most punctual flight time for Panama City to Santo Domingo flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Thursday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Panama City to Santo Domingo flights?

Over the past year, Copa Airlines has had the lowest number of delays on this route, with just 5% of flights being delayed.

Reviews of airlines servicing Santo Domingo

Check out reviews from past customers who have flown with Copa Airlines and Avianca from Panama City to Santo Domingo to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

How long is the flight from Panama City to Santo Domingo?

What are the cheapest airlines flying from Panama City to Santo Domingo round-trip?

What are the most reliable airlines from Panama City to Santo Domingo?

Can I find deals for flights from Panama City to Santo Domingo that include hotel bookings?

How can I find direct flights from Panama City to Santo Domingo?

Can I find deals for business class flights from Panama City to Santo Domingo?

What is the cheapest month to book a flight from Panama City to Santo Domingo?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Santo Domingo by adding a car rental and/or hotel reservation to your travel itinerary.

Direct flights to Dominican Republic

Book a non-stop flight to one of these other cities located in Dominican Republic.

Search flights from Panama City to Santo Domingo by cabin class

Find flights from Panama City to Santo Domingo, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Panama City and Santo Domingo flights

Browse other Panama City and Santo Domingo flight options. Last updated on 28 October 2026.

Other flights from Panama City

Browse through other flights departing from Panama City. Flights are based on user searches made on Cheapflights and were last updated on 28 October 2026.

Popular flight searches

Check out other popular destinations found by fellow travellers in 2026

Other flights to Santo Domingo

Explore flights to Santo Domingo departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 28 October 2026.

Top 2 airlines flying from Panama City to Santo Domingo

Fly with Cheapflights

How does Cheapflights help users find flights from Panama City to Santo Domingo?

Why should you use Cheapflights to find cheap flight tickets from Panama City to Santo Domingo?

Can Cheapflights find flights from Panama City to Santo Domingo with no change fees?

Can Cheapflights notify me if prices for flights from Panama City to Santo Domingo become cheaper?

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Cheapest flights from Panama City to Santo Domingo
Explore the most affordable flight options available from Panama City to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 October 2026.

Best flights from Panama City to Santo Domingo
Discover carefully curated flight deals from Panama City to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 28 October 2026.

Direct flights from Panama City to Santo Domingo
Explore direct flight options from Panama City to Santo Domingo based on user searches, and compare prices and availability for your desired travel dates. Data last updated 28 October 2026.

Last-minute flights from Panama City to Santo Domingo
Discover last-minute flight deals from Panama City to Santo Domingo. Data last updated 28 October 2026 and is based on user searches.

One-way flights from Panama City to Santo Domingo
Search for one-way flight options from Panama City to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated 28 October 2026.

Panama City to Santo Domingo flights typically cost between C$ 673 and C$ 769 in December.
The cheapest round-trip price found within the last 5 days was C$ 690 on Copa Airlines (19 Dec-20 Dec).