Cheap flights from Santo Domingo to Panama City from C$ 399
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/10. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — PTY
13 Oct — 20 Oct1
Round-trip
1 adult
Economy
Round-trip
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Santo Domingo Las Americas to Panama City Tocumen Intl are usually found in January or February, booked 90 days in advance, depart on a Monday or Saturday and return on a Monday
Cheap flight deals from Santo Domingo to Panama City
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Cheapest flights from Santo Domingo to Panama City
Explore the most affordable flight options available from Santo Domingo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 13 September 2026.
Wed 16/912:45 p.m. -
1 stop12h 50m
Fri 18/94:25 a.m. -
1 stop6h 25m
Deal found 8/9C$ 795
Tue 27/107:07 p.m. -
Nonstop2h 33m
Sun 1/118:15 a.m. -
Nonstop2h 30m
Deal found 11/9C$ 842
Fri 30/1012:45 p.m. -
1 stop5h 30m
Sat 7/116:10 p.m. -
1 stop16h 40m
Deal found 10/9C$ 843
Sun 1/117:06 p.m. -
Nonstop2h 34m
Wed 11/117:39 a.m. -
Nonstop2h 27m
Deal found 11/9C$ 874
Thu 1/106:06 a.m. -
Nonstop2h 33m
Sat 10/108:11 a.m. -
Nonstop2h 30m
Deal found 10/9C$ 907
Thu 29/1012:45 p.m. -
1 stop13h 35m
Sun 1/116:10 p.m. -
1 stop16h 40m
Deal found 9/9C$ 909
Wed 28/106:45 p.m. -
1 stop7h 35m
Mon 9/1110:05 a.m. -
1 stop24h 45m
Deal found 10/9C$ 922
Sat 21/118:55 a.m. -
Nonstop2h 35m
Sat 12/128:15 a.m. -
Nonstop2h 27m
Deal found 8/9C$ 924
Wed 28/106:45 p.m. -
1 stop21h 30m
Fri 6/112:30 a.m. -
1 stop14h 20m
Deal found 9/9C$ 986
Fri 11/96:50 p.m. -
1 stop15h 25m
Tue 15/910:10 a.m. -
1 stop6h 45m
Deal found 11/9C$ 1,015
Sun 1/116:45 p.m. -
1 stop7h 35m
Mon 9/116:10 p.m. -
1 stop22h 40m
Deal found 9/9C$ 1,079
Tue 22/96:41 p.m. -
Nonstop2h 33m
Wed 21/108:11 a.m. -
Nonstop2h 30m
Deal found 11/9C$ 1,093
Best flights from Santo Domingo to Panama City
Discover carefully curated flight deals from Santo Domingo to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 13 September 2026.
Tue 10/116:45 p.m. -
1 stop7h 35m
Wed 11/1110:05 a.m. -
1 stop6h 45m
Deal found 8/9C$ 795
Thu 29/108:57 a.m. -
Nonstop2h 33m
Sat 31/109:42 a.m. -
Nonstop2h 30m
Deal found 11/9C$ 842
Fri 30/108:57 a.m. -
Nonstop2h 33m
Mon 9/119:42 a.m. -
Nonstop2h 28m
Deal found 12/9C$ 874
Sat 31/1012:12 p.m. -
Nonstop2h 33m
Sun 22/1112:44 p.m. -
Nonstop2h 28m
Deal found 10/9C$ 874
Sat 3/1012:42 p.m. -
Nonstop2h 33m
Sat 31/107:39 a.m. -
Nonstop2h 30m
Deal found 12/9C$ 874
Wed 23/912:42 p.m. -
Nonstop2h 33m
Wed 21/107:24 a.m. -
Nonstop2h 30m
Deal found 8/9C$ 907
Sat 3/106:41 p.m. -
Nonstop2h 33m
Sat 17/108:11 a.m. -
Nonstop2h 30m
Deal found 12/9C$ 907
Thu 8/108:47 a.m. -
Nonstop2h 33m
Sun 11/109:42 a.m. -
Nonstop2h 30m
Deal found 12/9C$ 907
Wed 7/106:41 p.m. -
Nonstop2h 33m
Sun 11/108:11 a.m. -
Nonstop2h 30m
Deal found 11/9C$ 907
Fri 25/92:16 p.m. -
Nonstop2h 33m
Wed 30/97:26 p.m. -
Nonstop2h 30m
Deal found 10/9C$ 907
Fri 25/912:42 p.m. -
Nonstop2h 33m
Mon 28/98:11 a.m. -
Nonstop2h 31m
Deal found 8/9C$ 907
Sat 20/212:05 p.m. -
Nonstop2h 40m
Sun 28/28:15 a.m. -
Nonstop2h 27m
Deal found 12/9C$ 907
Direct flights from Santo Domingo to Panama City
Explore direct flight options from Santo Domingo to Panama City based on user searches, and compare prices and availability for your desired travel dates. Data last updated 13 September 2026.
Tue 27/105:55 a.m. -
Nonstop2h 33m
Mon 2/1112:44 p.m. -
Nonstop2h 28m
Deal found 11/9C$ 842
Sun 1/117:06 p.m. -
Nonstop2h 34m
Sun 15/118:15 a.m. -
Nonstop2h 30m
Deal found 10/9C$ 874
Thu 1/106:06 a.m. -
Nonstop2h 33m
Sat 10/108:11 a.m. -
Nonstop2h 30m
Deal found 10/9C$ 907
Sat 21/118:55 a.m. -
Nonstop2h 35m
Sat 12/128:15 a.m. -
Nonstop2h 27m
Deal found 8/9C$ 924
Wed 23/912:42 p.m. -
Nonstop2h 33m
Wed 14/1012:44 p.m. -
Nonstop2h 30m
Deal found 11/9C$ 1,093
Sun 6/125:53 a.m. -
Nonstop2h 35m
Tue 8/129:42 a.m. -
Nonstop2h 32m
Deal found 8/9C$ 1,208
Sun 4/1012:42 p.m. -
Nonstop2h 33m
Mon 5/108:11 a.m. -
Nonstop2h 30m
Deal found 11/9C$ 1,273
Last-minute flights from Santo Domingo to Panama City
Discover last-minute flight deals from Santo Domingo to Panama City. Data last updated 13 September 2026 and is based on user searches.
Fri 11/96:50 p.m. -
1 stop15h 25m
Tue 15/910:10 a.m. -
1 stop6h 45m
Deal found 11/9C$ 1,015
Sun 13/912:42 p.m. -
Nonstop2h 33m
Sun 27/98:11 a.m. -
Nonstop2h 31m
Deal found 10/9C$ 1,208
Wed 16/912:45 p.m. -
1 stop12h 50m
Fri 18/94:25 a.m. -
1 stop6h 25m
Deal found 8/9C$ 795
Tue 22/912:42 p.m. -
Nonstop2h 33m
Tue 29/97:26 p.m. -
Nonstop2h 30m
Deal found 11/9C$ 1,093
Thu 1/102:16 p.m. -
Nonstop2h 33m
Wed 7/109:42 a.m. -
Nonstop2h 30m
Deal found 11/9C$ 907
Sat 24/1012:12 p.m. -
Nonstop2h 33m
Mon 2/1112:44 p.m. -
Nonstop2h 28m
Deal found 11/9C$ 874
Tue 27/107:07 p.m. -
Nonstop2h 33m
Sun 1/118:15 a.m. -
Nonstop2h 30m
Deal found 11/9C$ 842
Wed 28/106:45 p.m. -
1 stop7h 35m
Mon 9/1110:05 a.m. -
1 stop24h 45m
Deal found 10/9C$ 922
Wed 28/1012:45 p.m. -
1 stop5h 30m
Thu 5/112:30 a.m. -
1 stop14h 20m
Deal found 9/9C$ 986
Thu 29/1012:45 p.m. -
1 stop13h 35m
Sun 1/116:10 p.m. -
1 stop16h 40m
Deal found 9/9C$ 909
Fri 30/1012:45 p.m. -
1 stop5h 30m
Sat 7/116:10 p.m. -
1 stop16h 40m
Deal found 10/9C$ 843
Sat 31/1012:45 p.m. -
1 stop21h 25m
Sat 7/1110:05 a.m. -
1 stop6h 45m
Deal found 9/9C$ 1,079
One-way flights from Santo Domingo to Panama City
Search for one-way flight options from Santo Domingo to Panama City. Find affordable one-way fares based on user searches. Data last updated 13 September 2026.
Wed 28/1012:48 p.m. -
Nonstop2h 33m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 12/9C$ 399
Mon 26/107:09 a.m. -
2 stops29h 00m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 11/9C$ 466
Mon 11/112:45 p.m. -
1 stop5h 30m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 11/9C$ 499
Tue 24/1112:10 p.m. -
Nonstop2h 35m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 11/9C$ 859
Sat 3/103:20 p.m. -
2 stops28h 17m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 9/9C$ 1,630
Wed 9/126:00 a.m. -
3 stops33h 45m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 9/9C$ 1,766
Tue 12/12:53 p.m. -
3 stops30h 26m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 9/9C$ 1,867
Fri 15/16:00 a.m. -
3 stops33h 45m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 8/9C$ 2,167
Find flight deals from Santo Domingo to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 13 September 2026.
Customize your flight search to find flights from Santo Domingo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated 13 September 2026.
Use the filters below to find and compare flights from Santo Domingo to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest round-trip
Quickest round-trip
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Wed 28/10
12:48 p.m.-2:21 p.m.
Nonstop2h 33m
Panama City Tocumen Intl
Wed 31/12
12:00 a.m.-12:30 a.m.
Nonstop0h 00m
C$ 399
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Mon 26/10
7:09 a.m.-7:44 a.m.
1 stop25h 35m
Panama City Tocumen Intl
Wed 31/12
12:00 a.m.-12:30 a.m.
Nonstop0h 00m
C$ 491
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Tue 10/11
6:45 p.m.-1:20 a.m.
1 stop7h 35m
Panama City Tocumen Intl
Wed 11/11
10:05 a.m.-5:50 p.m.
1 stop6h 45m
C$ 795
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Thu 29/10
8:57 a.m.-10:30 a.m.
Nonstop2h 33m
Panama City Tocumen Intl
Sat 31/10
9:42 a.m.-1:12 p.m.
Nonstop2h 30m
C$ 842
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Thu 8/10
12:12 p.m.-1:45 p.m.
Nonstop2h 33m
Panama City Tocumen Intl
Wed 31/12
12:00 a.m.-12:30 a.m.
Nonstop0h 00m
C$ 859
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Mon 1/2
2:19 p.m.-3:58 p.m.
Nonstop2h 39m
Panama City Tocumen Intl
Wed 31/12
12:00 a.m.-12:30 a.m.
Nonstop0h 00m
C$ 859
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Mon 16/11
8:55 a.m.-10:30 a.m.
Nonstop2h 35m
Panama City Tocumen Intl
Wed 31/12
12:00 a.m.-12:30 a.m.
Nonstop0h 00m
C$ 859
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Fri 4/12
12:43 p.m.-2:21 p.m.
Nonstop2h 38m
Panama City Tocumen Intl
Wed 31/12
12:00 a.m.-12:30 a.m.
Nonstop0h 00m
C$ 859
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Fri 15/1
8:52 a.m.-10:30 a.m.
Nonstop2h 38m
Panama City Tocumen Intl
Wed 31/12
12:00 a.m.-12:30 a.m.
Nonstop0h 00m
C$ 859
Santo DomingoPanama City
SDQ Santo Domingo Las Americas - PTY Panama City Tocumen Intl
SDQPTY
Santo Domingo Las Americas
Thu 1/10
2:16 p.m.-3:49 p.m.
Nonstop2h 33m
Panama City Tocumen Intl
Wed 31/12
12:00 a.m.-12:30 a.m.
Nonstop0h 00m
C$ 859
Flights are sorted by cheapest round-trip flights first.
Deals found on 12/9
Showing 1-10 of 22 resultsSorted by cheapest first
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Best time to book a flight from Santo Domingo to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Santo Domingo with our price prediction graph.
SDQ-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santo Domingo to Panama City
Prices
Delays
How far ahead should I book a flight from Santo Domingo to Panama City?
The best time to book flights from Santo Domingo to Panama City is 89 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Santo Domingo to Panama City?
Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of C$ 727). Flying from Santo Domingo to Panama City in August is currently the most expensive (average of C$ 856). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from SDQ to PTY?
Find hourly flight availability from Santo Domingo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 13 September 2026.
It’s typically best to fly out from Santo Domingo to Panama City in the evening. Doing so could potentially save you 77% on the flight price compared to flying at noon, which is usually more expensive.
How much does it cost to fly round-trip from Santo Domingo to Panama City?
Airfare is typical for this route at the moment.
Santo Domingo to Panama City flights typically cost between C$ 741 and C$ 906 in November.The cheapest round-trip price found within the last 5 days was C$ 795 on Avianca (10 Nov-11 Nov).
How often are flights from Santo Domingo to Panama City delayed?
About 5% of weekly flights between Santo Domingo and Panama City have experienced delays in the past year, with the average delay time being 106 minutes.
What is the most punctual flight time for Santo Domingo to Panama City flights?
Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Saturday tends to have the lowest number of delays on this route, whereas Friday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Santo Domingo to Panama City flights?
Over the past year, Copa Airlines has had the lowest number of delays on this route, with just 5% of flights being delayed.
Related info for your journey
Find useful and relevant information for your journey from Santo Domingo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
How popular is this Santo Domingo to Panama City flight route?
Flights from Santo Domingo Las Americas to Panama City Tocumen Intl have been viewed 62 times in the past calendar month.
How long is the flight from Santo Domingo to Panama City?
Airlines like Avianca and Copa Airlines fly from Santo Domingo to Panama City in about 2h 33m. The time it takes to get you to your destination can typically vary by up to 5h 02m. The distance from Santo Domingo to Panama City is about 1476 km. This flight may include one or multiple stops.
What are the most reliable airlines from Santo Domingo to Panama City?
No one likes to see their flight delayed. When booking a flight from Santo Domingo to Panama City consider choosing Air France (92%), Copa Airlines (88%) or KLM (85%) as they are the most reliable in getting you off to your destination on time.
What are the cheapest flights from Santo Domingo to Panama City?
The cheapest flight price from Santo Domingo to Panama City is C$ 170. On average you can expect to pay C$ 889. The most popular route, (Santo Domingo Las Americas - Panama City Tocumen Intl), can usually be booked for C$ 818.
Can I find deals for flights from Santo Domingo to Panama City that include hotel bookings?
Yes. In addition to deals on Santo Domingo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Santo Domingo to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Panama City.
Can I find deals for business class flights from Santo Domingo to Panama City?
Yes. Cheapflights offers flight deals from Santo Domingo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Santo Domingo to Panama City?
Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of C$ 727). Flying from Santo Domingo to Panama City in August is currently the most expensive (average of C$ 856). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 13 September 2026.
Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Santo Domingo to Panama City?
Deals for Santo Domingo to Panama City flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.
Why should you use Cheapflights to find cheap flight tickets from Santo Domingo to Panama City?
Cheapflights simply makes it quick and affordable to book flights from Santo Domingo to Panama City by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.
Can Cheapflights find flights from Santo Domingo to Panama City with no change fees?
Certainly. Search results for flights to Panama City from Santo Domingo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Santo Domingo to Panama City become cheaper?
Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Panama City from Santo Domingo today and book when prices fit your budget.
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