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Cheap flights from Buffalo to Santo Domingo from C$ 211

BUF — SDQ
11 Oct — 18 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Buffalo to Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to Santo Domingo

Thu 12/116:00 a.m. -
1 stop6h 41m
Mon 16/116:00 a.m. -
1 stop17h 59m
Deal found 7/9C$ 522
Tue 29/97:42 p.m. -
1 stop16h 13m
Wed 28/101:53 p.m. -
1 stop9h 06m
Deal found 9/9C$ 544
Wed 14/108:50 a.m. -
1 stop7h 20m
Tue 20/103:50 p.m. -
1 stop8h 09m
Deal found 10/9C$ 547
Fri 23/107:42 p.m. -
1 stop16h 13m
Fri 30/101:53 p.m. -
1 stop9h 06m
Deal found 7/9C$ 562
Tue 27/106:00 a.m. -
1 stop6h 41m
Fri 30/101:53 p.m. -
1 stop9h 06m
Deal found 6/9C$ 611
Thu 12/113:20 p.m. -
1 stop9h 54m
Mon 16/113:57 p.m. -
1 stop9h 02m
Deal found 10/9C$ 616
Tue 6/106:30 a.m. -
1 stop16h 16m
Tue 13/103:20 p.m. -
1 stop7h 51m
Deal found 8/9C$ 619

Find flight deals from Buffalo to Santo Domingo

Round-trip from

C$ 522

One-way from

C$ 211

Popular in

April

Cheapest in

January

Average price

C$ 680
United Airlines
  • United Airlines
  • 12/11-16/11
  • 2 total stops
  • 24h 40m total
  • Buffalo to Santo Domingo
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JetBlue
  • JetBlue
  • 29/10-31/12
  • 1 total stop
  • 7h 07m total
  • Buffalo to Santo Domingo
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Highest demand for flights based on searches. 1% potential increase in price (C$ 21 potential increase over avg. RT price).
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Cheapest flight prices on average. 7% potential price decrease (C$ 84 potential savings vs. average RT price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Buffalo to Santo Domingo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Thu 29/10

10:51 a.m.-10:46 p.m.

1 stop11h 55m

Santo Domingo Las Americas

Wed 31/12

12:00 a.m.-11:30 p.m.

Nonstop0h 00m

C$ 232

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Wed 11/11

3:20 p.m.-2:14 a.m.

1 stop9h 54m

Santo Domingo Las Americas

Wed 31/12

12:00 a.m.-11:30 p.m.

Nonstop0h 00m

C$ 253
Quickest round-trip

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Wed 6/1

6:00 a.m.-3:06 p.m.

1 stop8h 06m

Santo Domingo Las Americas

Wed 31/12

12:00 a.m.-11:30 p.m.

Nonstop0h 00m

C$ 285

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Tue 5/1

10:20 a.m.-1:41 p.m.

2 stops26h 21m

Santo Domingo Las Americas

Wed 31/12

12:00 a.m.-11:30 p.m.

Nonstop0h 00m

C$ 293

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Wed 14/10

8:50 a.m.-4:10 p.m.

1 stop7h 20m

Santo Domingo Las Americas

Wed 21/10

3:36 p.m.-10:50 p.m.

1 stop7h 14m

C$ 544

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Tue 29/9

7:42 p.m.-11:55 a.m.

1 stop16h 13m

Santo Domingo Las Americas

Wed 28/10

1:53 p.m.-10:59 p.m.

1 stop9h 06m

C$ 544

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Wed 14/10

8:50 a.m.-4:10 p.m.

1 stop7h 20m

Santo Domingo Las Americas

Tue 20/10

3:50 p.m.-11:59 p.m.

1 stop8h 09m

C$ 547

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Tue 15/12

6:00 a.m.-11:46 p.m.

1 stop16h 46m

Santo Domingo Las Americas

Wed 31/12

12:00 a.m.-11:30 p.m.

Nonstop0h 00m

C$ 557

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Tue 27/10

6:00 a.m.-12:41 p.m.

1 stop6h 41m

Santo Domingo Las Americas

Fri 30/10

1:53 p.m.-10:59 p.m.

1 stop9h 06m

C$ 611

BuffaloSanto Domingo

BUF Buffalo - SDQ Santo Domingo Las Americas

BUFSDQ

Buffalo

Thu 12/11

7:00 a.m.-7:30 p.m.

1 stop11h 30m

Santo Domingo Las Americas

Mon 16/11

8:55 p.m.-10:35 a.m.

1 stop14h 40m

C$ 630

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Sorted by cheapest first

Best time to book a flight from Buffalo to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Buffalo with our price prediction graph.
Estimated round-trip price

Related info for your journey

  • How long is the flight from Buffalo to Santo Domingo?

    Airlines like JetBlue and United Airlines fly from Buffalo to Santo Domingo in about 6h 41m. The time it takes to get you to your destination can typically vary by up to 39m. The distance from Buffalo to Santo Domingo is about 2853 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Buffalo to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Buffalo to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Santo Domingo.

  • Can I find deals for business class flights from Buffalo to Santo Domingo?

    Yes. Cheapflights offers flight deals from Buffalo to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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