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Cheap flights from Santo Domingo to Panama City from C$ 639

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — PTY
4 Aug — 11 Aug1
1 adult

Cheap flight deals from Santo Domingo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 July 2025.

Round-trip from

C$ 639

Popular in

March

Cheapest in

October

Average price

C$ 684
Avianca
  • Avianca
  • 9/9-13/9
  • 2 total stops
  • 13h 20m total
  • Santo Domingo to Panama City
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Highest demand for flights based on searches. 5% potential increase in price (C$ 51 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease (C$ 7 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Santo Domingo to Panama City

Cheapest flights from Santo Domingo to Panama City
Explore the most affordable flight options available from Santo Domingo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 July 2025.

Tue 9/96:10 p.m.SDQ - PTY
1 stop7h 00mAvianca
Fri 12/93:25 a.m.PTY - SDQ
1 stop6h 25mAvianca
Deal found 30/7C$ 639
Tue 9/97:40 a.m.SDQ - PTY
2 stops32h 00mMultiple Airlines
Sat 13/99:55 a.m.PTY - SDQ
1 stop6h 20mMultiple Airlines
Deal found 30/7C$ 716
Thu 25/95:25 a.m.SDQ - PTY
Nonstop2h 33mCopa Airlines
Sun 28/912:44 p.m.PTY - SDQ
Nonstop2h 33mCopa Airlines
Deal found 30/7C$ 720
Sun 5/1012:47 p.m.SDQ - PTY
2 stops30h 50mUnited Airlines
Sat 11/103:30 p.m.PTY - SDQ
2 stops33h 20mUnited Airlines
Deal found 29/7C$ 1,788
Thu 4/92:47 p.m.SDQ - PTY
1 stop23h 03mDelta
Thu 18/92:10 p.m.PTY - SDQ
2 stops21h 10mDelta
Deal found 30/7C$ 2,155

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santo Domingo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 30 July 2025.
Use the filters below to find and compare flights from Santo Domingo to Panama City that are best for you.

Fly from

Santo Domingo

Fly to

Panama City

Route

Depart

Return

Price

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Tue 9/9

6:10 p.m.-12:10 a.m.

1 stop7h 00m

Panama City Tocumen Intl

Fri 12/9

3:25 a.m.-10:50 a.m.

1 stop6h 25m

C$ 639

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Tue 9/9

7:40 a.m.-2:40 p.m.

2 stops32h 00m

Panama City Tocumen Intl

Sat 13/9

9:55 a.m.-5:15 p.m.

1 stop6h 20m

C$ 716

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Thu 25/9

5:25 a.m.-6:58 a.m.

Nonstop2h 33m

Panama City Tocumen Intl

Sun 28/9

12:44 p.m.-4:17 p.m.

Nonstop2h 33m

C$ 720

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Sun 5/10

12:47 p.m.-6:37 p.m.

2 stops30h 50m

Panama City Tocumen Intl

Sat 11/10

3:30 p.m.-1:50 a.m.

2 stops33h 20m

C$ 1,788

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Thu 4/9

2:47 p.m.-12:50 p.m.

1 stop23h 03m

Panama City Tocumen Intl

Thu 18/9

2:10 p.m.-12:20 p.m.

2 stops21h 10m

C$ 2,155

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Thu 25/12

6:15 p.m.-2:40 p.m.

2 stops21h 25m

C$ 640

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Wed 6/8

2:07 p.m.-3:42 p.m.

Nonstop2h 35m

C$ 756

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Sat 15/11

2:53 p.m.-2:45 p.m.

2 stops24h 52m

C$ 1,372

Flights are sorted by cheapest round-trip flights first.

Deals found on 30/7

Best time to book a flight from Santo Domingo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Panama City

How far ahead should I book a flight from Santo Domingo to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Panama City. Price data was last updated on 25 July 2025.

The best time to book flights from Santo Domingo to Panama City is 41 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Panama City?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of C$ 542). Flying from Santo Domingo to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to PTY?

Find hourly flight availability from Santo Domingo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 July 2025.

It’s typically best to fly out from Santo Domingo to Panama City at noon. Doing so could potentially save you 10% on the flight price compared to flying in the morning, which is usually more expensive.

Weekly flight availability from Santo Domingo to Panama City

Explore weekly flight availability from Santo Domingo to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 30 July 2025.

The most flights from SDQ to PTY are scheduled on a Monday (9 on average). You will have fewer flight options on Friday, which is when the least amount of flights are scheduled (5 on average).

How much does it cost to fly round-trip from Santo Domingo to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 30 July 2025.
Check out reviews from past customers who have flown with Delta,Copa Airlines, andUnited Airlines from Santo Domingo to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews
Check prices

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews
Check prices

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Copa Airlines
7.5
Good
1,493 reviews
Delta
8.0
Very good
7,980 reviews
Check prices

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,896 reviews
Delta
8.0
Very good
7,980 reviews
Check prices

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Avianca
6.7
Okay
2,387 reviews
Delta
8.0
Very good
7,980 reviews
Check prices

Boarding

8.2

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Entertainment

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santo Domingo to Panama City flight route?

    Flights from Santo Domingo Las Americas to Panama City Tocumen Intl have been viewed 20 times in the past calendar month.

  • What are the cheapest airlines flying from Santo Domingo to Panama City round-trip?

    Cheapflights users have booked flights from Santo Domingo to Panama City round-trip from C$ 639. Other airlines that can offer you cheap pricing are Copa Airlines, from C$ 720, and United Airlines, from C$ 1,788.

  • What are the cheapest airlines to fly from Santo Domingo to Panama City one-way?

    C$ 640 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and United Airlines, with prices starting from C$ 756 and C$ 1,372, respectively.

  • What are the most reliable airlines from Santo Domingo to Panama City?

    No one likes to see their flight delayed. When booking a flight from Santo Domingo to Panama City consider choosing KLM (94%), Copa Airlines (94%) or Air France (93%) as they are the most reliable in getting you off to your destination on time.

  • Can I find deals for flights from Santo Domingo to Panama City that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Panama City.

  • Can I find deals for business class flights from Santo Domingo to Panama City?

    Yes. Cheapflights offers flight deals from Santo Domingo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Panama City?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of C$ 542). Flying from Santo Domingo to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Certainly. Search results for flights to Panama City from Santo Domingo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Santo Domingo to Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Panama City from Santo Domingo today and book when prices fit your budget.

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