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Cheap flights from Santo Domingo to Panama City from C$ 189

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 26/6. Fares are subject to change and may not be available on all flights or dates of travel.
SDQ — PTY
17 Jun — 24 Jun1
1 adult

Cheap flight deals from Santo Domingo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Santo Domingo (SDQ) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 12 June 2025.

Round-trip from

C$ 457

One-way from

C$ 189

Popular in

March

Cheapest in

July

Average price

C$ 651

Good one-way deal

C$ 450 or less
Avianca
  • Avianca
  • 29/7-9/8
  • 2 total stops
  • 19h 45m total
  • Santo Domingo to Panama City
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Avianca
  • Avianca
  • 26/6
  • 1 total stop
  • 5h 45m total
  • Santo Domingo to Panama City
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Highest demand for flights based on searches. 6% potential increase in price (C$ 61 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease (C$ 8 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Price to beat on a one-way flight from Santo Domingo Las Americas to Panama City Tocumen Intl.
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Find flight deals from Santo Domingo to Panama City

Cheapest flights from Santo Domingo to Panama City
Explore the most affordable flight options available from Santo Domingo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 12 June 2025.

Fri 20/68:53 a.m.SDQ - PTY
Nonstop2h 37mCopa Airlines
Mon 23/67:26 a.m.PTY - SDQ
Nonstop2h 31mCopa Airlines
Deal found 10/6C$ 865
Mon 20/101:10 p.m.SDQ - PTY
2 stops26h 04mUnited Airlines
Fri 24/103:30 p.m.PTY - SDQ
3 stops45h 36mUnited Airlines
Deal found 12/6C$ 1,918
Fri 3/102:09 p.m.SDQ - PTY
2 stops23h 40mDelta
Tue 7/102:12 p.m.PTY - SDQ
2 stops26h 40mDelta
Deal found 10/6C$ 8,728

Cheapflights Fare Finder

Customize your flight search to find flights from Santo Domingo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 12 June 2025.
Use the filters below to find and compare flights from Santo Domingo to Panama City that are best for you.

Fly from

Santo Domingo

Fly to

Panama City

Route

Depart

Return

Price

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Sun 29/6

5:21 a.m.-6:58 a.m.

Nonstop2h 37m

Panama City Tocumen Intl

Sun 31/8

6:55 p.m.-10:27 p.m.

Nonstop2h 32m

C$ 774

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Sat 26/7

3:20 p.m.-6:13 a.m.

2 stops15h 53m

Panama City Tocumen Intl

Sat 2/8

9:13 a.m.-1:50 a.m.

2 stops15h 37m

C$ 3,456

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Fri 3/10

2:09 p.m.-12:49 p.m.

2 stops23h 40m

Panama City Tocumen Intl

Tue 7/10

2:12 p.m.-5:52 p.m.

2 stops26h 40m

C$ 8,728

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Thu 26/6

11:45 a.m.-4:30 p.m.

1 stop5h 45m

C$ 189

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Thu 10/7

5:39 p.m.-7:14 p.m.

Nonstop2h 35m

C$ 733

Santo DomingoPanama City

SDQ - PTY

SDQPTY

Santo Domingo Las Americas

Sat 26/7

1:10 p.m.-2:14 p.m.

2 stops26h 04m

C$ 1,507

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Best time to book a flight from Santo Domingo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santo Domingo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santo Domingo to Panama City

How far ahead should I book a flight from Santo Domingo to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Santo Domingo to Panama City. Price data was last updated on 9 June 2025.

The best time to book flights from Santo Domingo to Panama City is 27 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santo Domingo to Panama City?

Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of C$ 542). Flying from Santo Domingo to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SDQ to PTY?

Find hourly flight availability from Santo Domingo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 12 June 2025.

It’s typically best to fly out from Santo Domingo to Panama City at noon. Doing so could potentially save you 10% on the flight price compared to flying in the morning, which is usually more expensive.

Weekly flight availability from Santo Domingo to Panama City

Explore weekly flight availability from Santo Domingo to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 12 June 2025.

The most flights from SDQ to PTY are scheduled on a Monday (9 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 mm per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 12 June 2025.
Delta
8.0
Very good
7,946 reviews
Check prices

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Sep 2023

AVL - LGA

Landing in Syracuse was ruff no bad weather just bad piloting. A/C barely. Working from LGA to Syracuse.
Delta
8.0
Very good
7,946 reviews
Delta
8.0
Very good
7,946 reviews
Check prices

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Sep 2023

AVL - LGA

Landing in Syracuse was ruff no bad weather just bad piloting. A/C barely. Working from LGA to Syracuse.
Copa Airlines
7.5
Good
1,451 reviews
Delta
8.0
Very good
7,946 reviews
Check prices

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Sep 2023

AVL - LGA

Landing in Syracuse was ruff no bad weather just bad piloting. A/C barely. Working from LGA to Syracuse.
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,946 reviews
Check prices

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Sep 2023

AVL - LGA

Landing in Syracuse was ruff no bad weather just bad piloting. A/C barely. Working from LGA to Syracuse.
Avianca
6.7
Okay
2,345 reviews
Delta
8.0
Very good
7,946 reviews
Check prices

Overall

8.0

Entertainment

7.9

Comfort

7.9

Food

7.3

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Anonymous,Sep 2023

AVL - LGA

Landing in Syracuse was ruff no bad weather just bad piloting. A/C barely. Working from LGA to Syracuse.

Related info for your journey

Find useful and relevant information for your journey from Santo Domingo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Santo Domingo to Panama City flight route?

    Flights from Santo Domingo Las Americas to Panama City Tocumen Intl have been viewed 22 times in the past calendar month.

  • What are the cheapest airlines flying from Santo Domingo to Panama City round-trip?

    Cheapflights users have booked flights from Santo Domingo to Panama City round-trip from C$ 457. Other airlines that can offer you cheap pricing are Copa Airlines, from C$ 681, and United Airlines, from C$ 3,456. Avianca is 26% cheaper than the average price of flights available within the next 90 days to this destination.

  • What are the cheapest airlines to fly from Santo Domingo to Panama City one-way?

    C$ 189 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and United Airlines, with prices starting from C$ 733 and C$ 1,507, respectively.

  • What are the most reliable airlines from Santo Domingo to Panama City?

    No one likes to see their flight delayed. When booking a flight from Santo Domingo to Panama City consider choosing Copa Airlines (92%), KLM (92%) or Air France (92%) as they are the most reliable in getting you off to your destination on time.

  • What are the cheapest flights from Santo Domingo to Panama City?

    The cheapest flight price from Santo Domingo to Panama City is C$ 317. On average you can expect to pay C$ 450. The most popular route, (Santo Domingo Las Americas - Panama City Tocumen Intl), can usually be booked for C$ 634.

  • Can I find deals for flights from Santo Domingo to Panama City that include hotel bookings?

    Yes. In addition to deals on Santo Domingo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santo Domingo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santo Domingo to Panama City.

  • Can I find deals for business class flights from Santo Domingo to Panama City?

    Yes. Cheapflights offers flight deals from Santo Domingo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santo Domingo to Panama City?

    Currently, January is the cheapest month in which you can book a flight from Santo Domingo to Panama City (average of C$ 542). Flying from Santo Domingo to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Certainly. Search results for flights to Panama City from Santo Domingo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Santo Domingo to Panama City become cheaper?

Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Panama City from Santo Domingo today and book when prices fit your budget.

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