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Cheap flights from Buffalo to South Carolina from C$ 165

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 17/6. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — CHS
4 Jun — 11 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Buffalo to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5 May 2026.

Thu 18/64:10 p.m.
BUF
-
SAV
1 stop4h 20m
Southwest
Thu 25/67:55 p.m.
SAV
-
BUF
1 stop4h 15m
Southwest
Deal found 3/5C$ 335
Fri 26/65:12 p.m.
BUF
-
SAV
1 stop6h 42m
Delta
Sat 4/77:50 a.m.
SAV
-
BUF
1 stop7h 19m
Delta
Deal found 30/4C$ 341
Thu 20/86:00 a.m.
BUF
-
SAV
2 stops8h 47m
United Airlines
Sat 22/83:14 p.m.
SAV
-
BUF
1 stop5h 54m
United Airlines
Deal found 3/5C$ 348
Mon 8/67:27 p.m.
BUF
-
CHS
1 stop5h 18m
Delta
Sat 13/69:10 a.m.
CHS
-
BUF
1 stop6h 56m
Delta
Deal found 30/4C$ 350
Sun 24/512:50 p.m.
BUF
-
CHS
2 stops7h 20m
Southwest
Thu 28/54:45 p.m.
CHS
-
BUF
1 stop6h 35m
Southwest
Deal found 4/5C$ 356
Tue 19/57:39 p.m.
BUF
-
CHS
1 stop4h 20m
Delta
Fri 12/65:34 p.m.
CHS
-
BUF
1 stop7h 04m
Delta
Deal found 2/5C$ 363
Wed 21/1012:09 p.m.
BUF
-
SAV
1 stop5h 34m
Delta
Sun 25/106:50 p.m.
SAV
-
BUF
1 stop5h 05m
Delta
Deal found 2/5C$ 374
Sun 14/66:00 a.m.
BUF
-
SAV
1 stop4h 52m
United Airlines
Fri 19/67:15 p.m.
SAV
-
BUF
1 stop4h 44m
United Airlines
Deal found 30/4C$ 377
Sat 22/87:04 p.m.
BUF
-
CHS
1 stop4h 49m
United Airlines
Tue 25/87:00 a.m.
CHS
-
BUF
2 stops7h 22m
United Airlines
Deal found 5/5C$ 384
Fri 15/57:39 p.m.
BUF
-
SAV
1 stop4h 01m
Delta
Mon 18/57:59 p.m.
SAV
-
BUF
1 stop4h 00m
Delta
Deal found 30/4C$ 385
Mon 18/57:39 p.m.
BUF
-
CHS
1 stop4h 20m
Delta
Mon 8/66:24 p.m.
CHS
-
BUF
1 stop5h 35m
Delta
Deal found 2/5C$ 385
Sun 19/76:15 a.m.
BUF
-
CHS
1 stop3h 56m
United Airlines
Sat 25/77:46 p.m.
CHS
-
BUF
1 stop4h 13m
United Airlines
Deal found 2/5C$ 390

Find flight deals from Buffalo to South Carolina

Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated 5 May 2026.

Round-trip from

C$ 335

One-way from

C$ 165

Popular in

March

Cheapest in

September

Average price

C$ 506
Southwest
  • Southwest
  • 18/6-25/6
  • 2 total stops
  • 8h 35m total
  • Buffalo to South Carolina
Search Deals
Frontier
  • Frontier
  • 17/6
  • 2 total stops
  • 21h 24m total
  • Buffalo to South Carolina
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (C$ 101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (C$ 20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to South Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 5 May 2026.
Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 13/10

7:40 p.m.-11:59 p.m.

1 stop4h 19m

Savannah/Hilton Head

Thu 15/10

11:00 a.m.-3:12 p.m.

1 stop4h 12m

C$ 341

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 25/8

6:00 a.m.-10:54 a.m.

1 stop4h 54m

Savannah/Hilton Head

Sat 29/8

1:00 p.m.-9:08 p.m.

1 stop8h 08m

C$ 341

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Thu 24/9

7:40 p.m.-12:04 a.m.

1 stop4h 24m

Savannah/Hilton Head

Sun 27/9

7:50 p.m.-11:58 p.m.

1 stop4h 08m

C$ 341

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Fri 21/8

7:19 p.m.-12:21 a.m.

1 stop5h 02m

Savannah/Hilton Head

Tue 25/8

5:35 a.m.-11:11 a.m.

1 stop5h 36m

C$ 341

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Sun 11/10

7:40 p.m.-11:59 p.m.

1 stop4h 19m

Savannah/Hilton Head

Tue 13/10

8:45 a.m.-3:27 p.m.

1 stop6h 42m

C$ 341

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Wed 3/6

7:00 p.m.-11:52 p.m.

1 stop4h 52m

Charleston

Tue 9/6

3:08 p.m.-9:03 p.m.

1 stop5h 55m

C$ 350

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Tue 2/6

7:00 p.m.-11:52 p.m.

1 stop4h 52m

Charleston

Tue 9/6

3:08 p.m.-9:03 p.m.

1 stop5h 55m

C$ 350

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Wed 17/6

7:27 p.m.-12:36 a.m.

1 stop5h 09m

Charleston

Mon 22/6

6:39 p.m.-12:03 a.m.

1 stop5h 24m

C$ 350

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Mon 8/6

7:27 p.m.-12:45 a.m.

1 stop5h 18m

Charleston

Sat 13/6

9:10 a.m.-4:06 p.m.

1 stop6h 56m

C$ 350

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Thu 28/5

7:39 p.m.-11:59 p.m.

1 stop4h 20m

Charleston

Thu 4/6

6:55 p.m.-11:32 p.m.

1 stop4h 37m

C$ 350

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/5

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

How far ahead should I book a flight from Buffalo to South Carolina?

The best time to book flights from Buffalo to South Carolina is 69 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, June is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 109). Flying from Buffalo to South Carolina in January is currently the most expensive (average of C$ 321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to South Carolina?

Reviews of airlines servicing South Carolina

Get insights into the airlines that provide service to South Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to South Carolina. Reviews last updated 5 May 2026.
Get a feel of what it's like to fly with Southwest,Delta, andJetBlue from Buffalo to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
7.9
Good
4,305 reviews
Check prices

Overall

7.9

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Southwest
7.9
Good
4,305 reviews
Southwest
7.9
Good
4,305 reviews
Check prices

Overall

7.9

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Delta
7.9
Good
8,459 reviews
Southwest
7.9
Good
4,305 reviews
Check prices

Overall

7.9

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
JetBlue
7.2
Good
2,977 reviews
Southwest
7.9
Good
4,305 reviews
Check prices

Overall

7.9

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
American Airlines
7.1
Good
11,668 reviews
Southwest
7.9
Good
4,305 reviews
Check prices

Overall

7.9

Comfort

8.0

Entertainment

7.5

Food

7.0

Boarding

8.1

Crew

8.6

Reviews

1 / 20
2.0
Mediocre

Dominic,Mar 2026

MCO - SMF

I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to South Carolina?

    For a flight from Buffalo to South Carolina, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.

  • How long is the flight from Buffalo to South Carolina?

    Departing from Buffalo to South Carolina will take you 3h 56m. Airlines will cover a distance of 1122 km. This flight may include one or multiple stops.

  • What are the most popular routes from Buffalo to South Carolina?

    When deciding which route to take from Buffalo to South Carolina consider Buffalo - Myrtle Beach Intl, Buffalo - Charlotte Douglas or Buffalo - Savannah/Hilton Head as they are the most popular.

  • Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

  • Can I find deals for business class flights from Buffalo to South Carolina?

    Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South Carolina?

    Currently, June is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 109). Flying from Buffalo to South Carolina in January is currently the most expensive (average of C$ 321). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top 4 airlines flying from Buffalo to South Carolina

Discover the top 4 airlines that operate flights from Buffalo to South Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 5 May 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapestC$ 175AverageC$ 431FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
American AirlinesCheapestC$ 215AverageC$ 406FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
JetBlueCheapestC$ 245AverageC$ 577FlexibilityNo cancel feeOn-time62%
Search JetBlue flights
SouthwestCheapestC$ 270AverageC$ 479FlexibilityNo cancel feeOn-time63%
Search Southwest flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Buffalo to South Carolina?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Buffalo to South Carolina. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to South Carolina?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Buffalo to South Carolina for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Buffalo to South Carolina with no change fees?

Certainly. Search results for flights to South Carolina from Buffalo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Buffalo to South Carolina become cheaper?

Yes, Cheapflights offers price alerts on Buffalo to South Carolina flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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