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Cheap flights from Buffalo to South Carolina from C$ 185

BUF — CHS
27 Oct — 3 Nov1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Buffalo to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to South Carolina

Mon 19/107:00 a.m. -
1 stop7h 12m
Sat 24/1011:05 a.m. -
1 stop4h 09m
Deal found 23/9C$ 356
Wed 21/107:00 a.m. -
1 stop7h 12m
Tue 27/109:35 a.m. -
1 stop5h 23m
Deal found 24/9C$ 358
Wed 21/107:00 a.m. -
1 stop7h 12m
Sat 24/1012:25 p.m. -
1 stop7h 34m
Deal found 22/9C$ 359
Mon 9/113:05 p.m. -
1 stop4h 10m
Fri 13/1111:00 a.m. -
1 stop3h 25m
Deal found 23/9C$ 362
Wed 11/117:00 a.m. -
1 stop4h 42m
Sat 14/115:19 p.m. -
1 stop6h 38m
Deal found 23/9C$ 369
Wed 21/107:59 p.m. -
1 stop4h 16m
Sat 24/103:05 p.m. -
2 stops8h 45m
Deal found 22/9C$ 376
Wed 11/116:00 a.m. -
2 stops7h 56m
Wed 18/112:52 p.m. -
2 stops8h 07m
Deal found 24/9C$ 383
Thu 12/116:00 a.m. -
1 stop4h 06m
Mon 16/113:29 p.m. -
1 stop5h 07m
Deal found 22/9C$ 390
Wed 11/116:00 a.m. -
2 stops8h 27m
Thu 19/117:52 p.m. -
1 stop3h 52m
Deal found 24/9C$ 397
Wed 21/106:00 a.m. -
1 stop4h 10m
Mon 26/106:05 a.m. -
1 stop4h 33m
Deal found 26/9C$ 403
Wed 25/116:00 a.m. -
1 stop5h 08m
Tue 1/126:02 p.m. -
1 stop6h 02m
Deal found 25/9C$ 411
Sun 11/106:00 a.m. -
1 stop4h 10m
Sat 17/106:29 p.m. -
1 stop5h 30m
Deal found 23/9C$ 428

Find flight deals from Buffalo to South Carolina

Round-trip from

C$ 356

One-way from

C$ 185

Popular in

March

Cheapest in

October

Average price

C$ 546
JetBlue
  • JetBlue
  • 19/10-24/10
  • 2 total stops
  • 11h 21m total
  • Buffalo to South Carolina
Search Deals
Delta
  • Delta
  • 23/10-31/12
  • 1 total stop
  • 5h 04m total
  • Buffalo to South Carolina
Search Deals
Highest demand for flights based on searches. 6% potential increase in price (C$ 52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (C$ 17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloCharleston

BUF Buffalo - CHS Charleston

BUFCHS

Buffalo

Sun 22/11

6:00 a.m.-12:52 p.m.

1 stop6h 52m

Charleston

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 185

BuffaloCharleston

BUF Buffalo - CHS Charleston

BUFCHS

Buffalo

Sat 24/10

1:48 p.m.-9:41 p.m.

1 stop7h 53m

Charleston

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 185

BuffaloCharleston

BUF Buffalo - CHS Charleston

BUFCHS

Buffalo

Mon 19/10

6:00 a.m.-10:33 a.m.

1 stop4h 33m

Charleston

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 185

BuffaloCharleston

BUF Buffalo - CHS Charleston

BUFCHS

Buffalo

Fri 23/10

6:55 p.m.-11:59 p.m.

1 stop5h 04m

Charleston

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 185

BuffaloMyrtle Beach

BUF Buffalo - MYR Myrtle Beach Intl

BUFMYR

Buffalo

Tue 10/11

8:05 a.m.-6:25 p.m.

2 stops10h 20m

Myrtle Beach Intl

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 226

BuffaloMyrtle Beach

BUF Buffalo - MYR Myrtle Beach Intl

BUFMYR

Buffalo

Tue 23/3

6:19 a.m.-12:13 p.m.

1 stop5h 54m

Myrtle Beach Intl

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 235
Quickest round-trip

BuffaloCharleston

BUF Buffalo - CHS Charleston

BUFCHS

Buffalo

Sun 11/10

6:00 a.m.-10:02 a.m.

1 stop4h 02m

Charleston

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 246

BuffaloMyrtle Beach

BUF Buffalo - MYR Myrtle Beach Intl

BUFMYR

Buffalo

Fri 6/11

5:30 p.m.-10:05 p.m.

1 stop4h 35m

Myrtle Beach Intl

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 257

BuffaloCharleston

BUF Buffalo - CHS Charleston

BUFCHS

Buffalo

Sun 22/11

11:00 a.m.-9:00 p.m.

2 stops10h 00m

Charleston

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 288

BuffaloHilton Head Island

BUF Buffalo - HHH Hilton Head Island

BUFHHH

Buffalo

Sat 24/10

6:00 a.m.-11:43 a.m.

1 stop5h 43m

Hilton Head Island

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 288

Flights are sorted by cheapest round-trip flights first.

Deals found on 23/9

Showing 1-10 of 58 resultsSorted by cheapest first
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Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, February is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 440). Flying from Buffalo to South Carolina in March is currently the most expensive (average of C$ 624). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to South Carolina?

Airfare is typical for this route at the moment.
Buffalo to South Carolina flights typically cost between C$ 337 and C$ 607 in October.
The cheapest round-trip price found within the last 5 days was C$ 356 on JetBlue (19 Oct-24 Oct).

How far ahead should I book a flight from Buffalo to South Carolina?

The best time to book flights from Buffalo to South Carolina is 35 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Southwest,Delta, andJetBlue from Buffalo to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,203 reviews
Check prices

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.
Southwest
8.0
Very good
4,203 reviews
Southwest
8.0
Very good
4,203 reviews
Check prices

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.
Delta
7.8
Good
8,610 reviews
Southwest
8.0
Very good
4,203 reviews
Check prices

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.
JetBlue
7.1
Good
3,041 reviews
Southwest
8.0
Very good
4,203 reviews
Check prices

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.
American Airlines
7.0
Good
12,099 reviews
Southwest
8.0
Very good
4,203 reviews
Check prices

Boarding

8.1

Crew

8.6

Entertainment

7.5

Food

7.0

Overall

8.0

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Edward,Sep 2026

MCO - BWI

Changed flight which was easy. Gate Agent booked me from extra leg room seat on original flight to row 15 on new flight that did not have extra leg room - even though it was an exit row. The row in front of me with extra leg room had an empty seat.

Related info for your journey

  • What airport do you fly from for flights from Buffalo to South Carolina?

    For a flight from Buffalo to South Carolina, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.

  • How long is the flight from Buffalo to South Carolina?

    Departing from Buffalo to South Carolina will take you 7h 07m. Airlines will cover a distance of 1122 km. This flight may include one or multiple stops.

  • What are the most popular routes from Buffalo to South Carolina?

    When deciding which route to take from Buffalo to South Carolina consider Buffalo - Charlotte Douglas, Buffalo - Charleston or Buffalo - Myrtle Beach Intl as they are the most popular.

  • Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

    Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to South Carolina?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

  • Can I find deals for business class flights from Buffalo to South Carolina?

    Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to South Carolina?

    Currently, February is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 440). Flying from Buffalo to South Carolina in March is currently the most expensive (average of C$ 624). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Buffalo to South Carolina

AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapestC$ 274AverageC$ 600FlexibilityNo cancel feeOn-time62%
Search JetBlue flights
DeltaCheapestC$ 278AverageC$ 518FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
American AirlinesCheapestC$ 278AverageC$ 448FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
SouthwestCheapestC$ 306AverageC$ 492FlexibilityNo cancel feeOn-time63%
Search Southwest flights

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How does Cheapflights help users find flights from Buffalo to South Carolina?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Buffalo to South Carolina. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to South Carolina?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Buffalo to South Carolina for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Buffalo to South Carolina with no change fees?

Certainly. Search results for flights to South Carolina from Buffalo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Buffalo to South Carolina become cheaper?

Yes, Cheapflights offers price alerts on Buffalo to South Carolina flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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