How long is the flight from Buffalo to South Carolina?

Departing from Buffalo to South Carolina will take you 4h 52m. Airlines will cover a distance of 1221 km. This flight may include one or multiple stops.

In terms of precipitation, rainfall in South Carolina ranges from 76.0 - 165.0 mm per month. July is typically the wettest month, when rainfall can reach 165.0 mm. November is typically the driest time to visit South Carolina when rainfall is around 76.0 mm.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 26.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 7.0 C).

What are the most popular routes from Buffalo to South Carolina?

When deciding which route to take from Buffalo to South Carolina consider Buffalo - Charlotte Douglas, Buffalo - Savannah/Hilton Head or Buffalo - Myrtle Beach Intl as they are the most popular.

What are the most popular airlines that fly from Buffalo to South Carolina?

The most popular airlines flying from Buffalo to South Carolina are Southwest, American Airlines and Delta. Something to consider prior to booking your flight.

What airport do you fly from for flights from Buffalo to South Carolina?

For a flight from Buffalo to South Carolina, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.

Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Buffalo to South Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

Can I find deals for business class flights from Buffalo to South Carolina?

Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 125+ Flights from Buffalo to South Carolina

Cheap flight deals from Buffalo to South Carolina

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 December 2025.

Wed 24/122:50 p.m.BUF - CHS

1 stop4h 14mUnited Airlines

Wed 31/1211:40 a.m.CHS - BUF

1 stop5h 14mUnited Airlines

Deal found 17/12C$ 277

Sat 20/129:28 a.m.BUF - CLT

1 stop10h 41mFrontier

Wed 24/129:04 p.m.CLT - BUF

1 stop16h 08mFrontier

Deal found 16/12C$ 344

Mon 22/1210:43 a.m.BUF - CLT

1 stop10h 15mFrontier

Wed 24/129:04 p.m.CLT - BUF

1 stop16h 08mFrontier

Deal found 16/12C$ 373

Wed 24/125:52 p.m.BUF - CLT

1 stop3h 58mDelta

Thu 25/121:05 p.m.CLT - BUF

1 stop4h 07mDelta

Deal found 16/12C$ 376

Fri 19/129:42 a.m.BUF - CLT

1 stop10h 27mFrontier

Wed 24/122:51 p.m.CLT - BUF

1 stop5h 49mFrontier

Deal found 16/12C$ 473

Wed 17/127:00 a.m.BUF - CLT

1 stop6h 28mDelta

Tue 6/17:35 p.m.CLT - BUF

1 stop14h 19mDelta

Deal found 15/12C$ 517

Sat 20/129:28 a.m.BUF - CLT

1 stop5h 33mFrontier

Tue 23/129:24 p.m.CLT - BUF

1 stop23h 16mFrontier

Deal found 16/12C$ 519

Wed 17/129:14 a.m.BUF - CLT

1 stop6h 59mDelta

Mon 5/19:59 a.m.CLT - BUF

1 stop12h 53mDelta

Deal found 15/12C$ 537

Wed 24/125:52 p.m.BUF - CLT

1 stop3h 58mDelta

Sun 28/126:00 a.m.CLT - BUF

1 stop5h 21mDelta

Deal found 16/12C$ 555

Thu 25/127:00 a.m.BUF - CHS

2 stops10h 05mSouthwest

Sun 28/128:05 p.m.CHS - BUF

1 stop4h 00mSouthwest

Deal found 17/12C$ 562

Sat 20/127:15 p.m.BUF - CLT

Nonstop2h 09mAmerican Airlines

Wed 24/124:48 p.m.CLT - BUF

Nonstop1h 43mAmerican Airlines

Deal found 16/12C$ 572

Thu 25/126:00 a.m.BUF - MYR

1 stop4h 26mDelta

Sun 28/1211:09 a.m.MYR - BUF

1 stop6h 38mDelta

Deal found 17/12C$ 573

Best flights from Buffalo to South Carolina
Discover carefully curated flight deals from Buffalo to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 18 December 2025.

Thu 15/19:55 a.m.BUF - SAV

1 stop4h 52mUnited Airlines

Thu 22/19:45 a.m.SAV - BUF

1 stop4h 29mUnited Airlines

Deal found 16/12C$ 276

Sun 24/56:16 a.m.BUF - CHS

1 stop6h 33mDelta

Wed 27/510:20 a.m.CHS - BUF

1 stop5h 39mDelta

Deal found 17/12C$ 277

Tue 3/27:00 a.m.BUF - SAV

1 stop7h 24mAmerican Airlines

Sat 7/27:34 a.m.SAV - BUF

1 stop4h 24mAmerican Airlines

Deal found 17/12C$ 280

Tue 26/512:25 p.m.BUF - CHS

1 stop6h 40mJetBlue

Fri 29/53:30 p.m.CHS - BUF

1 stop8h 25mJetBlue

Deal found 17/12C$ 292

Tue 3/25:50 a.m.BUF - CLT

1 stop4h 30mSouthwest

Tue 3/26:05 p.m.CLT - BUF

1 stop3h 50mSouthwest

Deal found 17/12C$ 376

Sat 23/512:07 p.m.BUF - CHS

1 stop4h 44mDelta

Thu 28/510:20 a.m.CHS - BUF

1 stop5h 39mDelta

Deal found 17/12C$ 277

Tue 26/56:00 a.m.BUF - CHS

1 stop4h 55mJetBlue

Tue 26/53:30 p.m.CHS - BUF

1 stop8h 25mJetBlue

Deal found 17/12C$ 295

Sun 24/512:07 p.m.BUF - CHS

1 stop4h 44mDelta

Thu 28/510:20 a.m.CHS - BUF

1 stop5h 39mDelta

Deal found 17/12C$ 277

Fri 2/16:30 a.m.BUF - CHS

1 stop7h 39mUnited Airlines

Tue 6/111:00 a.m.CHS - BUF

1 stop6h 40mUnited Airlines

Deal found 16/12C$ 320

Mon 25/59:45 a.m.BUF - CHS

1 stop4h 55mJetBlue

Fri 29/53:30 p.m.CHS - BUF

1 stop8h 25mJetBlue

Deal found 17/12C$ 303

Sat 23/512:07 p.m.BUF - CHS

1 stop4h 44mDelta

Fri 29/510:20 a.m.CHS - BUF

1 stop5h 39mDelta

Deal found 17/12C$ 277

Fri 2/16:30 a.m.BUF - CHS

1 stop7h 39mUnited Airlines

Wed 7/12:58 p.m.CHS - BUF

2 stops7h 33mUnited Airlines

Deal found 16/12C$ 327

Tue 3/27:00 a.m.BUF - SAV

1 stop4h 48mDelta

Sat 7/26:50 a.m.SAV - BUF

1 stop6h 19mDelta

Deal found 16/12C$ 280

Thu 29/112:14 p.m.BUF - SAV

1 stop4h 48mDelta

Sun 1/25:30 a.m.SAV - BUF

1 stop5h 38mDelta

Deal found 16/12C$ 280

Wed 13/57:40 a.m.BUF - SAV

2 stops9h 45mSouthwest

Mon 18/58:05 a.m.SAV - BUF

1 stop8h 35mSouthwest

Deal found 16/12C$ 427

Sun 18/12:49 p.m.BUF - SAV

1 stop4h 36mUnited Airlines

Thu 22/110:10 a.m.SAV - BUF

1 stop6h 34mUnited Airlines

Deal found 17/12C$ 372

Sat 7/211:24 a.m.BUF - CLT

1 stop5h 15mUnited Airlines

Sat 14/22:54 p.m.CLT - BUF

1 stop6h 08mUnited Airlines

Deal found 16/12C$ 376

Sat 28/34:57 p.m.BUF - CHS

1 stop4h 18mDelta

Thu 2/45:20 a.m.CHS - BUF

1 stop5h 41mDelta

Deal found 16/12C$ 322

Thu 8/19:55 a.m.BUF - SAV

2 stops11h 41mUnited Airlines

Thu 15/19:45 a.m.SAV - BUF

1 stop4h 29mUnited Airlines

Deal found 16/12C$ 379

Wed 8/47:30 p.m.BUF - SAV

1 stop4h 29mDelta

Mon 13/48:45 a.m.SAV - BUF

1 stop7h 14mDelta

Deal found 17/12C$ 329

Sat 24/12:49 p.m.BUF - CLT

1 stop4h 08mUnited Airlines

Mon 26/111:15 a.m.CLT - BUF

1 stop6h 25mUnited Airlines

Deal found 16/12C$ 404

Wed 4/32:58 p.m.BUF - SAV

1 stop6h 47mDelta

Sun 8/37:00 a.m.SAV - BUF

1 stop4h 01mDelta

Deal found 16/12C$ 346

Wed 29/46:00 a.m.BUF - CLT

2 stops11h 07mUnited Airlines

Mon 4/57:30 a.m.CLT - BUF

1 stop5h 56mUnited Airlines

Deal found 17/12C$ 411

Wed 13/512:07 p.m.BUF - SAV

1 stop6h 40mDelta

Mon 18/57:50 p.m.SAV - BUF

1 stop4h 07mDelta

Deal found 16/12C$ 346

Fri 30/19:55 a.m.BUF - CLT

1 stop4h 18mUnited Airlines

Mon 2/29:55 a.m.CLT - BUF

1 stop4h 19mUnited Airlines

Deal found 15/12C$ 431

Sat 28/34:57 p.m.BUF - CHS

1 stop4h 18mDelta

Fri 3/49:30 a.m.CHS - BUF

1 stop6h 29mDelta

Deal found 16/12C$ 364

Tue 13/16:00 a.m.BUF - MYR

1 stop5h 35mDelta

Tue 20/14:07 p.m.MYR - BUF

1 stop7h 21mDelta

Deal found 16/12C$ 376

Wed 4/210:37 a.m.BUF - CLT

1 stop5h 30mDelta

Sat 7/26:00 a.m.CLT - BUF

1 stop5h 45mDelta

Deal found 17/12C$ 376

Wed 15/43:50 p.m.BUF - CLT

1 stop5h 55mDelta

Mon 20/46:59 p.m.CLT - BUF

1 stop4h 57mDelta

Deal found 17/12C$ 404

Mon 1/66:16 a.m.BUF - CLT

1 stop4h 53mDelta

Sat 6/65:24 p.m.CLT - BUF

1 stop5h 39mDelta

Deal found 15/12C$ 404

Last-minute flights from Buffalo to South Carolina
Discover last-minute flight deals from Buffalo to South Carolina. Data last updated 18 December 2025 and is based on user searches.

Sat 20/129:28 a.m.BUF - CLT

1 stop10h 41mFrontier

Wed 24/129:04 p.m.CLT - BUF

1 stop16h 08mFrontier

Deal found 16/12C$ 344

Mon 22/1210:43 a.m.BUF - CLT

1 stop10h 15mFrontier

Wed 24/129:04 p.m.CLT - BUF

1 stop16h 08mFrontier

Deal found 16/12C$ 373

Wed 24/122:50 p.m.BUF - CHS

1 stop4h 14mUnited Airlines

Wed 31/1211:40 a.m.CHS - BUF

1 stop5h 14mUnited Airlines

Deal found 17/12C$ 277

Wed 24/125:52 p.m.BUF - CLT

1 stop3h 58mDelta

Thu 25/121:05 p.m.CLT - BUF

1 stop4h 07mDelta

Deal found 16/12C$ 376

Fri 2/16:30 a.m.BUF - CHS

1 stop7h 39mUnited Airlines

Wed 7/110:15 a.m.CHS - BUF

1 stop6h 29mUnited Airlines

Deal found 16/12C$ 320

Fri 2/16:30 a.m.BUF - CHS

1 stop7h 39mUnited Airlines

Tue 6/110:15 a.m.CHS - BUF

2 stops9h 10mUnited Airlines

Deal found 16/12C$ 327

Thu 8/18:30 a.m.BUF - SAV

1 stop6h 08mUnited Airlines

Thu 15/19:45 a.m.SAV - BUF

1 stop4h 29mUnited Airlines

Deal found 16/12C$ 372

Tue 13/16:00 a.m.BUF - MYR

1 stop5h 35mDelta

Tue 20/14:07 p.m.MYR - BUF

1 stop7h 21mDelta

Deal found 17/12C$ 376

Thu 15/19:55 a.m.BUF - SAV

1 stop4h 52mUnited Airlines

Thu 22/19:45 a.m.SAV - BUF

1 stop4h 29mUnited Airlines

Deal found 16/12C$ 276

Sun 25/16:20 p.m.BUF - CHS

1 stop5h 24mUnited Airlines

Thu 29/16:05 a.m.CHS - BUF

2 stops8h 09mUnited Airlines

Deal found 16/12C$ 380

Sun 25/16:00 a.m.BUF - CHS

1 stop6h 40mJetBlue

Thu 29/112:09 p.m.CHS - BUF

1 stop6h 38mJetBlue

Deal found 16/12C$ 382

Thu 29/112:14 p.m.BUF - SAV

1 stop4h 48mDelta

Sun 1/25:30 a.m.SAV - BUF

1 stop5h 38mDelta

Deal found 16/12C$ 280

One-way flights from Buffalo to South Carolina
Search for one-way flight options from Buffalo to South Carolina. Find affordable one-way fares based on user searches. Data last updated 18 December 2025.

Sat 18/412:50 p.m.BUF - SAV

1 stop6h 09mJetBlue

Deal found 16/12C$ 125

Thu 15/19:55 a.m.BUF - CHS

1 stop4h 53mUnited Airlines

Deal found 17/12C$ 136

Fri 17/44:57 p.m.BUF - SAV

1 stop7h 07mDelta

Deal found 16/12C$ 179

Sat 31/110:00 a.m.BUF - MYR

1 stop11h 04mMultiple Airlines

Deal found 17/12C$ 180

Thu 16/47:55 p.m.BUF - SAV

1 stop4h 04mUnited Airlines

Deal found 16/12C$ 189

Tue 3/25:50 a.m.BUF - CLT

1 stop4h 30mSouthwest

Deal found 17/12C$ 189

Fri 16/11:05 p.m.BUF - CLT

1 stop5h 45mSouthwest

Deal found 17/12C$ 216

Tue 17/31:20 p.m.BUF - CLT

2 stops8h 45mSouthwest

Deal found 17/12C$ 223

Wed 24/123:40 p.m.BUF - SAV

1 stop4h 40mSouthwest

Deal found 17/12C$ 237

Sun 15/36:02 a.m.BUF - MYR

1 stop5h 46mDelta

Deal found 16/12C$ 254

Sat 17/110:00 a.m.BUF - CLT

2 stops9h 35mSouthwest

Deal found 17/12C$ 265

Fri 17/49:25 a.m.BUF - SAV

2 stops9h 00mSouthwest

Deal found 16/12C$ 267

Find flight deals from Buffalo to South Carolina

Round-trip from	C$ 260
One-way from	C$ 125
Popular in	April
Cheapest in	October
Average price	C$ 532

JetBlue
26/5-28/5
2 total stops
13h 20m total
Buffalo to South Carolina

Search Deals

JetBlue
18/4
1 total stop
6h 09m total
Buffalo to South Carolina

Search Deals

Highest demand for flights based on searches. 10% potential increase in price (C$ 81 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease (C$ 18 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Thu 15/1

9:55 a.m.-2:47 p.m.

1 stop4h 52m

Savannah/Hilton Head

Thu 22/1

9:45 a.m.-2:14 p.m.

1 stop4h 29m

C$ 276

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Sun 24/5

6:16 a.m.-12:49 p.m.

1 stop6h 33m

Charleston

Wed 27/5

10:20 a.m.-3:59 p.m.

1 stop5h 39m

C$ 277

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Sat 23/5

12:07 p.m.-4:51 p.m.

1 stop4h 44m

Charleston

Thu 28/5

10:20 a.m.-3:59 p.m.

1 stop5h 39m

C$ 277

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Sun 24/5

12:07 p.m.-4:51 p.m.

1 stop4h 44m

Charleston

Thu 28/5

10:20 a.m.-3:59 p.m.

1 stop5h 39m

C$ 277

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Sat 23/5

12:07 p.m.-4:51 p.m.

1 stop4h 44m

Charleston

Fri 29/5

10:20 a.m.-3:59 p.m.

1 stop5h 39m

C$ 277

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 3/2

7:00 a.m.-2:24 p.m.

1 stop7h 24m

Savannah/Hilton Head

Sat 7/2

7:34 a.m.-11:58 a.m.

1 stop4h 24m

C$ 280

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 3/2

7:00 a.m.-11:48 a.m.

1 stop4h 48m

Savannah/Hilton Head

Sat 7/2

6:50 a.m.-1:09 p.m.

1 stop6h 19m

C$ 280

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Thu 29/1

12:14 p.m.-5:02 p.m.

1 stop4h 48m

Savannah/Hilton Head

Sun 1/2

5:30 a.m.-11:08 a.m.

1 stop5h 38m

C$ 280

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Tue 26/5

12:25 p.m.-7:05 p.m.

1 stop6h 40m

Charleston

Fri 29/5

3:30 p.m.-11:55 p.m.

1 stop8h 25m

C$ 292

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Tue 26/5

6:00 a.m.-10:55 a.m.

1 stop4h 55m

Charleston

Tue 26/5

3:30 p.m.-11:55 p.m.

1 stop8h 25m

C$ 295

Flights are sorted by cheapest round-trip flights first.

Deals found on 16/12

Showing 1-10 of 51 results

...

Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, April is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 65). Flying from Buffalo to South Carolina in March is currently the most expensive (average of C$ 180). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SC?

One of the essential ways to save on airfare from Buffalo to South Carolina is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the afternoon could potentially save you up to 24% on airfare.

What is the cheapest day to fly from Buffalo to South Carolina?

Travelers seeking maximum savings on their Buffalo to South Carolina flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Buffalo to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

7.9

Good

4,250 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Southwest

7.9

Good

4,250 reviews

Southwest

7.9

Good

4,250 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Delta

7.9

Good

8,005 reviews

Southwest

7.9

Good

4,250 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

American Airlines

7.2

Good

11,054 reviews

Southwest

7.9

Good

4,250 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

What airport do you fly from for flights from Buffalo to South Carolina?
For a flight from Buffalo to South Carolina, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.
How long is the flight from Buffalo to South Carolina?
Departing from Buffalo to South Carolina will take you 4h 52m. Airlines will cover a distance of 1221 km. This flight may include one or multiple stops.
What are the most popular routes from Buffalo to South Carolina?
When deciding which route to take from Buffalo to South Carolina consider Buffalo - Charlotte Douglas, Buffalo - Savannah/Hilton Head or Buffalo - Myrtle Beach Intl as they are the most popular.
Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?
Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Buffalo to South Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.
Can I find deals for business class flights from Buffalo to South Carolina?
Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Buffalo to South Carolina?
Currently, April is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 65). Flying from Buffalo to South Carolina in March is currently the most expensive (average of C$ 180). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

South Carolina car rentals

Charleston Airport car rentals

Myrtle Beach Intl Airport car rentals

Greenville Airport car rentals

Columbia Metropolitan Airport car rentals

Hilton Head Island Airport car rentals

Florence Airport car rentals

Myrtle Beach car rentals

Charleston car rentals

Greenville car rentals

Hilton Head Island car rentals

Columbia car rentals

Direct flights to United States

Top 3 airlines flying from Buffalo to South Carolina

Airline	Cheapest	Average	Flexibility	On-time
Delta	CheapestC$ 263	AverageC$ 381	FlexibilityNo cancel fee	On-timeN/A	Search Delta flights
Southwest	CheapestC$ 273	AverageC$ 556	FlexibilityNo cancel fee	On-time63%	Search Southwest flights
American Airlines	CheapestC$ 300	AverageC$ 500	FlexibilityNo cancel fee	On-time71%	Search American Airlines flights

Fly with Cheapflights

How does Cheapflights help users find flights from Buffalo to South Carolina?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Buffalo to South Carolina. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to South Carolina?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Buffalo to South Carolina for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Buffalo to South Carolina with no change fees?

Certainly. Search results for flights to South Carolina from Buffalo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Buffalo to South Carolina become cheaper?

Yes, Cheapflights offers price alerts on Buffalo to South Carolina flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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Cheap flights from Buffalo to South Carolina from C$ 125

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 18/4. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South CarolinaExplore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 December 2025.

Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 December 2025.

Find flight deals from Buffalo to South Carolina

Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated 18 December 2025.

Round-trip from

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Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.

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Everything you need to know about your flight from Buffalo to South Carolina

What is the cheapest month to book a flight from Buffalo to South Carolina?

What is the cheapest time of day to fly from BUF to SC?

Find hourly flight availability from Buffalo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 18 December 2025.

What is the cheapest day to fly from Buffalo to South Carolina?

Use this chart to determine the cheapest time to fly round-trip from Buffalo to South Carolina. Price data was last updated on 16 December 2024.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Southwest,Delta, andAmerican Airlines from Buffalo to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Buffalo to South Carolina?

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What are the most popular routes from Buffalo to South Carolina?

Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

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Can I find deals for business class flights from Buffalo to South Carolina?

What is the cheapest month to book a flight from Buffalo to South Carolina?

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Alternative routes for Buffalo to South Carolina

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Top 3 airlines flying from Buffalo to South Carolina

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Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 18 December 2025.