How long is the flight from Buffalo to South Carolina?

Departing from Buffalo to South Carolina will take you 4h 22m. Airlines will cover a distance of 1221 km. This flight may include one or multiple stops.

What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

The cheapest airlines for a one-way flight from Buffalo to South Carolina are Frontier (C$ 116), JetBlue (C$ 153), and American Airlines (C$ 174).

In terms of precipitation, rainfall in South Carolina ranges from 76.0 - 165.0 mm per month. July is typically the wettest month, when rainfall can reach 165.0 mm. November is typically the driest time to visit South Carolina when rainfall is around 76.0 mm.

If weather is an important factor for your trip to South Carolina, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 26.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 7.0 C).

What are the most popular routes from Buffalo to South Carolina?

When deciding which route to take from Buffalo to South Carolina consider Buffalo - Charlotte Douglas, Buffalo - Myrtle Beach Intl or Buffalo - Savannah/Hilton Head as they are the most popular.

What are the most popular airlines that fly from Buffalo to South Carolina?

The most popular airlines flying from Buffalo to South Carolina are American Airlines, Delta and Southwest. Something to consider prior to booking your flight.

How far in advance should I book a flight from Buffalo to South Carolina?

To save on the cost of your flight from Buffalo to South Carolina, book at least 29 days before your planned departure. Booking around this time can save you about 111% on the cost of this flight compared to booking a flight leaving this week. We have found prices from C$ 482 if you need a flight within two weeks. For flights within the next 72 hours, you can find tickets from as low as C$ 819.

What is the cheapest month to fly from Buffalo to South Carolina?

Flights from Buffalo to South Carolina lean towards being more expensive in April. Prices are generally better when you fly from Buffalo to South Carolina in September, with the cheapest ticket starting at C$ 274.

What airport do you fly from for flights from Buffalo to South Carolina?

For a flight from Buffalo to South Carolina, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.

Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Buffalo to South Carolina?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.

Can I find deals for business class flights from Buffalo to South Carolina?

Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 116+ Cheap Flights from Buffalo to South Carolina

Cheap flight deals from Buffalo to South Carolina

Round-trip from	C$ 250
One-way from	C$ 116
Popular in	April
Cheapest in	September
Average price	C$ 434

JetBlue
22/10-30/10
2 total stops
9h 39m total
Buffalo to South Carolina

Search Deals

Frontier
27/9
1 total stop
12h 44m total
Buffalo to South Carolina

Search Deals

Highest demand for flights based on searches. 8% potential increase in price (C$ 67 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease (C$ 14 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Find flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Wed 22/106:00 a.m.BUF - CHS

1 stop4h 25mJetBlue

Thu 30/106:05 a.m.CHS - BUF

1 stop5h 14mJetBlue

Deal found 15/9C$ 250

Thu 30/107:00 a.m.BUF - CHS

1 stop6h 19mJetBlue

Sun 2/115:05 a.m.CHS - BUF

1 stop5h 14mJetBlue

Deal found 15/9C$ 278

Mon 20/106:00 a.m.BUF - SAV

1 stop5h 40mJetBlue

Tue 28/1011:19 a.m.SAV - BUF

1 stop4h 20mJetBlue

Deal found 14/9C$ 286

Wed 22/106:00 a.m.BUF - SAV

1 stop5h 40mJetBlue

Tue 28/1011:19 a.m.SAV - BUF

1 stop4h 20mJetBlue

Deal found 14/9C$ 296

Sun 21/125:30 a.m.BUF - SAV

1 stop4h 55mSouthwest

Thu 25/121:20 p.m.SAV - BUF

1 stop7h 20mSouthwest

Deal found 15/9C$ 298

Fri 24/107:30 p.m.BUF - SAV

1 stop4h 28mDelta

Wed 29/106:40 a.m.SAV - BUF

1 stop4h 21mDelta

Deal found 14/9C$ 322

Tue 7/106:30 a.m.BUF - SAV

2 stops8h 14mUnited Airlines

Wed 8/101:15 p.m.SAV - BUF

1 stop7h 58mUnited Airlines

Deal found 15/9C$ 329

Sat 4/106:00 a.m.BUF - SAV

1 stop5h 39mJetBlue

Wed 8/104:10 p.m.SAV - BUF

1 stop4h 50mJetBlue

Deal found 14/9C$ 330

Wed 29/107:00 a.m.BUF - CHS

1 stop6h 19mJetBlue

Sat 1/1111:14 a.m.CHS - BUF

1 stop10h 46mJetBlue

Deal found 14/9C$ 334

Mon 24/1110:50 a.m.BUF - MYR

1 stop6h 25mSouthwest

Mon 1/128:15 p.m.MYR - BUF

1 stop3h 50mSouthwest

Deal found 14/9C$ 344

Sat 18/101:05 p.m.BUF - MYR

1 stop6h 15mSouthwest

Wed 22/108:25 a.m.MYR - BUF

1 stop4h 05mSouthwest

Deal found 15/9C$ 347

Sat 11/107:38 p.m.BUF - CHS

1 stop4h 27mAmerican Airlines

Wed 15/106:15 p.m.CHS - BUF

1 stop4h 38mAmerican Airlines

Deal found 14/9C$ 347

Best flights from Buffalo to South Carolina
Discover carefully curated flight deals from Buffalo to South Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 15 September 2025.

Wed 22/106:00 a.m.BUF - CHS

1 stop4h 25mJetBlue

Thu 30/106:05 a.m.CHS - BUF

1 stop5h 14mJetBlue

Deal found 14/9C$ 250

Tue 3/26:16 a.m.BUF - SAV

1 stop5h 21mDelta

Sat 7/25:10 p.m.SAV - BUF

1 stop6h 47mDelta

Deal found 14/9C$ 322

Tue 3/21:31 p.m.BUF - SAV

1 stop4h 22mAmerican Airlines

Sat 7/211:02 a.m.SAV - BUF

1 stop7h 02mAmerican Airlines

Deal found 15/9C$ 322

Sat 18/101:05 p.m.BUF - MYR

1 stop6h 15mSouthwest

Wed 22/108:25 a.m.MYR - BUF

1 stop4h 05mSouthwest

Deal found 15/9C$ 347

Tue 21/107:07 a.m.BUF - MYR

1 stop7h 35mUnited Airlines

Fri 24/105:57 p.m.MYR - BUF

1 stop4h 45mUnited Airlines

Deal found 15/9C$ 366

Thu 30/107:00 a.m.BUF - CHS

1 stop6h 19mJetBlue

Sun 2/115:05 a.m.CHS - BUF

1 stop5h 14mJetBlue

Deal found 14/9C$ 278

Tue 21/106:00 a.m.BUF - SAV

1 stop5h 40mJetBlue

Wed 29/1012:25 p.m.SAV - BUF

1 stop6h 47mJetBlue

Deal found 14/9C$ 286

Tue 3/36:16 a.m.BUF - SAV

1 stop5h 21mDelta

Thu 5/37:25 a.m.SAV - BUF

1 stop7h 11mDelta

Deal found 13/9C$ 322

Tue 21/107:00 a.m.BUF - SAV

1 stop8h 15mJetBlue

Tue 28/1011:19 a.m.SAV - BUF

1 stop4h 20mJetBlue

Deal found 14/9C$ 286

Mon 24/1112:45 p.m.BUF - MYR

2 stops8h 45mSouthwest

Mon 1/128:15 p.m.MYR - BUF

1 stop3h 50mSouthwest

Deal found 14/9C$ 351

Tue 21/105:45 p.m.BUF - SAV

1 stop5h 40mDelta

Mon 27/106:59 p.m.SAV - BUF

1 stop4h 40mDelta

Deal found 14/9C$ 322

Sat 18/104:38 p.m.BUF - CLT

1 stop4h 34mUnited Airlines

Sat 25/1010:25 a.m.CLT - BUF

1 stop6h 28mUnited Airlines

Deal found 15/9C$ 377

Direct flights from Buffalo to South Carolina
Explore direct flight options from Buffalo to South Carolina based on user searches, and compare prices and availability for your desired travel dates. Data last updated 15 September 2025.

Thu 16/107:38 p.m.BUF - CLT

Nonstop1h 56mAmerican Airlines

Sun 19/105:01 p.m.CLT - BUF

Nonstop1h 51mAmerican Airlines

Deal found 13/9C$ 406

Tue 23/121:37 p.m.BUF - CLT

Nonstop2h 03mAmerican Airlines

Sun 28/124:48 p.m.CLT - BUF

Nonstop1h 42mAmerican Airlines

Deal found 14/9C$ 551

Thu 25/97:29 p.m.BUF - CLT

Nonstop1h 59mAmerican Airlines

Sun 28/910:25 p.m.CLT - BUF

Nonstop1h 47mAmerican Airlines

Deal found 14/9C$ 669

Thu 25/911:50 a.m.BUF - CLT

Nonstop2h 00mAmerican Airlines

Sat 27/94:09 p.m.CLT - BUF

Nonstop1h 50mAmerican Airlines

Deal found 14/9C$ 714

Last-minute flights from Buffalo to South Carolina
Discover last-minute flight deals from Buffalo to South Carolina. Data last updated 15 September 2025 and is based on user searches.

Sat 4/106:00 a.m.BUF - SAV

1 stop5h 39mJetBlue

Wed 8/104:10 p.m.SAV - BUF

1 stop4h 50mJetBlue

Deal found 14/9C$ 330

Tue 7/106:30 a.m.BUF - SAV

2 stops8h 14mUnited Airlines

Wed 8/101:15 p.m.SAV - BUF

1 stop7h 58mUnited Airlines

Deal found 15/9C$ 329

Sat 11/107:38 p.m.BUF - CHS

1 stop4h 27mAmerican Airlines

Wed 15/106:15 p.m.CHS - BUF

1 stop4h 38mAmerican Airlines

Deal found 14/9C$ 347

Wed 15/107:00 a.m.BUF - CHS

1 stop5h 10mDelta

Mon 20/107:05 p.m.CHS - BUF

1 stop4h 34mDelta

Deal found 15/9C$ 351

Sat 18/101:05 p.m.BUF - MYR

1 stop6h 15mSouthwest

Wed 22/108:25 a.m.MYR - BUF

1 stop4h 05mSouthwest

Deal found 15/9C$ 347

Mon 20/106:00 a.m.BUF - SAV

1 stop5h 40mJetBlue

Wed 29/1012:25 p.m.SAV - BUF

1 stop6h 47mJetBlue

Deal found 14/9C$ 286

Wed 22/106:00 a.m.BUF - CHS

1 stop4h 25mJetBlue

Thu 30/106:05 a.m.CHS - BUF

1 stop5h 14mJetBlue

Deal found 15/9C$ 250

Wed 22/106:00 a.m.BUF - SAV

1 stop5h 40mJetBlue

Tue 28/1011:19 a.m.SAV - BUF

1 stop4h 20mJetBlue

Deal found 14/9C$ 296

Thu 23/107:30 p.m.BUF - SAV

1 stop4h 28mDelta

Mon 27/106:59 p.m.SAV - BUF

1 stop4h 40mDelta

Deal found 14/9C$ 354

Fri 24/107:30 p.m.BUF - SAV

1 stop4h 28mDelta

Mon 27/106:59 p.m.SAV - BUF

1 stop4h 40mDelta

Deal found 14/9C$ 322

Wed 29/107:00 a.m.BUF - CHS

1 stop6h 19mJetBlue

Sat 1/1111:14 a.m.CHS - BUF

1 stop10h 46mJetBlue

Deal found 14/9C$ 334

Thu 30/107:00 a.m.BUF - CHS

1 stop6h 19mJetBlue

Sun 2/115:05 a.m.CHS - BUF

1 stop5h 14mJetBlue

Deal found 15/9C$ 278

One-way flights from Buffalo to South Carolina
Search for one-way flight options from Buffalo to South Carolina. Find affordable one-way fares based on user searches. Data last updated 15 September 2025.

Sat 27/97:11 p.m.BUF - CLT

1 stop12h 44mFrontier

Deal found 14/9C$ 116

Sat 11/109:45 p.m.BUF - CLT

1 stop10h 15mFrontier

Deal found 14/9C$ 128

Wed 22/106:00 a.m.BUF - SAV

1 stop5h 40mJetBlue

Deal found 15/9C$ 153

Tue 21/106:20 a.m.BUF - MYR

1 stop4h 14mDelta

Deal found 14/9C$ 174

Fri 24/107:30 p.m.BUF - CHS

1 stop4h 29mDelta

Deal found 15/9C$ 178

Sun 12/107:07 a.m.BUF - SAV

1 stop7h 37mUnited Airlines

Deal found 15/9C$ 186

Wed 12/116:00 a.m.BUF - CLT

1 stop4h 15mSouthwest

Deal found 13/9C$ 189

Tue 14/106:03 a.m.BUF - CLT

1 stop5h 07mDelta

Deal found 15/9C$ 192

Fri 24/103:10 p.m.BUF - MYR

1 stop7h 10mSouthwest

Deal found 13/9C$ 193

Sat 13/128:30 a.m.BUF - CLT

2 stops10h 40mSouthwest

Deal found 14/9C$ 196

Wed 3/126:15 a.m.BUF - CLT

2 stops11h 25mSouthwest

Deal found 14/9C$ 203

Sat 11/107:38 p.m.BUF - MYR

1 stop4h 21mAmerican Airlines

Deal found 15/9C$ 206

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Wed 22/10

6:00 a.m.-10:25 a.m.

1 stop4h 25m

Charleston

Thu 30/10

6:05 a.m.-11:19 a.m.

1 stop5h 14m

C$ 250

BuffaloCharleston

BUF - CHS

BUFCHS

Buffalo

Thu 30/10

7:00 a.m.-1:19 p.m.

1 stop6h 19m

Charleston

Sun 2/11

5:05 a.m.-10:19 a.m.

1 stop5h 14m

C$ 278

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 21/10

6:00 a.m.-11:40 a.m.

1 stop5h 40m

Savannah/Hilton Head

Wed 29/10

12:25 p.m.-7:12 p.m.

1 stop6h 47m

C$ 286

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 21/10

7:00 a.m.-3:15 p.m.

1 stop8h 15m

Savannah/Hilton Head

Tue 28/10

11:19 a.m.-3:39 p.m.

1 stop4h 20m

C$ 286

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Mon 20/10

6:00 a.m.-11:40 a.m.

1 stop5h 40m

Savannah/Hilton Head

Tue 28/10

11:19 a.m.-3:39 p.m.

1 stop4h 20m

C$ 286

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Wed 22/10

6:00 a.m.-11:40 a.m.

1 stop5h 40m

Savannah/Hilton Head

Wed 29/10

12:25 p.m.-7:12 p.m.

1 stop6h 47m

C$ 296

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 3/2

6:16 a.m.-11:37 a.m.

1 stop5h 21m

Savannah/Hilton Head

Sat 7/2

5:10 p.m.-11:57 p.m.

1 stop6h 47m

C$ 322

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 3/2

1:31 p.m.-5:53 p.m.

1 stop4h 22m

Savannah/Hilton Head

Sat 7/2

11:02 a.m.-6:04 p.m.

1 stop7h 02m

C$ 322

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 3/3

6:16 a.m.-11:37 a.m.

1 stop5h 21m

Savannah/Hilton Head

Thu 5/3

7:25 a.m.-2:36 p.m.

1 stop7h 11m

C$ 322

BuffaloSavannah

BUF - SAV

BUFSAV

Buffalo

Tue 21/10

5:45 p.m.-11:25 p.m.

1 stop5h 40m

Savannah/Hilton Head

Mon 27/10

6:59 p.m.-11:39 p.m.

1 stop4h 40m

C$ 322

Flights are sorted by cheapest round-trip flights first.

Deals found on 14/9

Showing 1-10 of 60 results

...

Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

What is the cheapest month to book a flight from Buffalo to South Carolina?

Currently, September is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 407). Flying from Buffalo to South Carolina in March is currently the most expensive (average of C$ 507). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SC?

When flying from Buffalo to South Carolina, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Buffalo to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,242 reviews

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Delta

8.0

Very good

7,954 reviews

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

United Airlines

7.4

Good

8,929 reviews

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

What airport do you fly from for flights from Buffalo to South Carolina?
For a flight from Buffalo to South Carolina, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.
How long is the flight from Buffalo to South Carolina?
Departing from Buffalo to South Carolina will take you 4h 22m. Airlines will cover a distance of 1221 km. This flight may include one or multiple stops.
What are the cheapest airlines to fly from Buffalo to South Carolina one-way?
The cheapest airlines for a one-way flight from Buffalo to South Carolina are Frontier (C$ 116), JetBlue (C$ 153), and American Airlines (C$ 174).
What are the most popular routes from Buffalo to South Carolina?
When deciding which route to take from Buffalo to South Carolina consider Buffalo - Charlotte Douglas, Buffalo - Myrtle Beach Intl or Buffalo - Savannah/Hilton Head as they are the most popular.
Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?
Yes. In addition to deals on Buffalo to South Carolina flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Buffalo to South Carolina?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to South Carolina.
Can I find deals for business class flights from Buffalo to South Carolina?
Yes. Cheapflights offers flight deals from Buffalo to South Carolina by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Buffalo to South Carolina?
Currently, September is the cheapest month in which you can book a flight from Buffalo to South Carolina (average of C$ 407). Flying from Buffalo to South Carolina in March is currently the most expensive (average of C$ 507). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Complete your trip

South Carolina car rentals

Charleston Airport car rentals

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Direct flights to United States

Top 4 airlines flying from Buffalo to South Carolina

Airline	Cheapest	Average	Flexibility	On-time
Delta	CheapestC$ 264	AverageC$ 381	FlexibilityNo cancel fee	On-timeN/A	Search Delta flights
Southwest	CheapestC$ 274	AverageC$ 541	FlexibilityNo cancel fee	On-time63%	Search Southwest flights
American Airlines	CheapestC$ 278	AverageC$ 406	FlexibilityNo cancel fee	On-time71%	Search American Airlines flights
United Airlines	CheapestC$ 553	AverageC$ 757	FlexibilityNo cancel fee	On-time69%	Search United Airlines flights

Fly with Cheapflights

How does Cheapflights help users find flights from Buffalo to South Carolina?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Buffalo to South Carolina. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to South Carolina?

Cheapflights taps into our reliable network of hundreds of airlines and travel agencies to find the best deals for flights from Buffalo to South Carolina for you. Better yet — we are completely free to use.

Can Cheapflights find flights from Buffalo to South Carolina with no change fees?

Certainly. Search results for flights to South Carolina from Buffalo shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Buffalo to South Carolina become cheaper?

Yes, Cheapflights offers price alerts on Buffalo to South Carolina flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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Cheap flights from Buffalo to South Carolina from C$ 116

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 27/9. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Buffalo to South Carolina

Keep the following information in mind while searching for Buffalo to South Carolina flight deals. Data was last updated 15 September 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Buffalo to South Carolina

Cheapest flights from Buffalo to South CarolinaExplore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to South Carolina that are best for you.

Best time to book a flight from Buffalo to South Carolina

Have a flexible travel schedule? Discover the best time to fly to South Carolina from Buffalo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to South Carolina

What is the cheapest month to book a flight from Buffalo to South Carolina?

What is the cheapest time of day to fly from BUF to SC?

Find hourly flight availability from Buffalo to South Carolina. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 15 September 2025.

Reviews of airlines servicing South Carolina

Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Buffalo to South Carolina by reading reviews from past customers. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to South Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Buffalo to South Carolina?

How long is the flight from Buffalo to South Carolina?

What are the cheapest airlines to fly from Buffalo to South Carolina one-way?

What are the most popular routes from Buffalo to South Carolina?

Can I find deals for flights from Buffalo to South Carolina that include hotel bookings?

How can I find direct flights from Buffalo to South Carolina?

Can I find deals for business class flights from Buffalo to South Carolina?

What is the cheapest month to book a flight from Buffalo to South Carolina?

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Alternative routes for Buffalo to South Carolina

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Top 4 airlines flying from Buffalo to South Carolina

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Cheapest flights from Buffalo to South Carolina
Explore the most affordable flight options available from Buffalo to South Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.