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Cheap flights from Santiago to Santo Domingo from C$ 429
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/11. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — SDQ
9 Nov — 16 Nov1
Cheap flight deals from Santiago to Santo Domingo
Enter your travel dates to find the best prices.
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Best
Last-minute
One-way
Cheapest flights from Santiago to Santo DomingoExplore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 October 2026.
Explore the most affordable flight options available from Santiago to Santo Domingo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 October 2026.
Wed 9/121:27 a.m. -
1 stop10h 35m
Thu 24/128:55 a.m. -
1 stop13h 40m
Deal found 8/10C$ 817
Sat 19/125:07 a.m. -
1 stop12h 06m
Sun 10/17:05 p.m. -
1 stop28h 18m
Deal found 8/10C$ 850
Mon 21/121:27 a.m. -
1 stop22h 31m
Fri 15/18:52 a.m. -
1 stop10h 26m
Deal found 7/10C$ 883
Wed 21/105:22 a.m. -
1 stop18h 34m
Wed 28/102:25 p.m. -
1 stop14h 30m
Deal found 5/10C$ 921
Thu 31/1210:00 a.m. -
1 stop12h 40m
Thu 7/12:05 p.m. -
1 stop12h 30m
Deal found 7/10C$ 924
Wed 16/123:48 a.m. -
1 stop20h 10m
Mon 1/38:48 a.m. -
1 stop13h 51m
Deal found 6/10C$ 929
Sun 25/105:22 a.m. -
1 stop13h 45m
Sun 1/115:55 a.m. -
1 stop17h 24m
Deal found 8/10C$ 954
Tue 1/1212:20 p.m. -
1 stop28h 53m
Sun 10/17:05 p.m. -
1 stop24h 13m
Deal found 8/10C$ 966
Sat 26/1212:20 p.m. -
1 stop14h 48m
Thu 18/25:53 a.m. -
1 stop13h 26m
Deal found 7/10C$ 987
Tue 15/1212:20 p.m. -
1 stop11h 38m
Sat 2/112:06 p.m. -
1 stop16h 51m
Deal found 8/10C$ 998
Tue 13/103:57 a.m. -
1 stop19h 59m
Wed 21/108:47 a.m. -
1 stop10h 45m
Deal found 9/10C$ 1,025
Thu 17/125:07 a.m. -
1 stop12h 06m
Sat 30/112:06 p.m. -
1 stop13h 47m
Deal found 8/10C$ 1,031
Best flights from Santiago to Santo DomingoDiscover carefully curated flight deals from Santiago to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 10 October 2026.
Discover carefully curated flight deals from Santiago to Santo Domingo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 10 October 2026.
Wed 9/121:27 a.m. -
1 stop10h 35m
Thu 24/128:55 a.m. -
1 stop13h 40m
Deal found 8/10C$ 817
Sat 12/1212:20 p.m. -
1 stop14h 48m
Sat 26/128:55 a.m. -
1 stop10h 16m
Deal found 5/10C$ 817
Sat 19/1212:20 p.m. -
1 stop24h 22m
Sun 10/17:05 p.m. -
1 stop28h 18m
Deal found 8/10C$ 850
Sun 13/121:07 a.m. -
1 stop26h 01m
Wed 6/12:19 p.m. -
1 stop12h 27m
Deal found 5/10C$ 850
Sat 19/125:07 a.m. -
1 stop22h 01m
Sat 26/1212:43 p.m. -
1 stop10h 35m
Deal found 9/10C$ 850
Mon 21/121:07 a.m. -
1 stop22h 51m
Tue 29/125:53 a.m. -
1 stop19h 55m
Deal found 9/10C$ 850
Tue 15/1212:20 p.m. -
1 stop11h 38m
Fri 1/112:42 p.m. -
1 stop9h 58m
Deal found 8/10C$ 850
Sat 5/121:07 a.m. -
1 stop11h 35m
Sun 6/127:03 p.m. -
1 stop24h 08m
Deal found 6/10C$ 850
Mon 21/123:19 a.m. -
1 stop20h 39m
Fri 15/17:05 p.m. -
1 stop28h 18m
Deal found 8/10C$ 883
Wed 23/125:07 a.m. -
1 stop22h 01m
Thu 21/18:52 a.m. -
1 stop13h 48m
Deal found 5/10C$ 883
Tue 22/121:27 a.m. -
1 stop22h 31m
Sun 31/17:05 p.m. -
1 stop27h 36m
Deal found 8/10C$ 883
Last-minute flights from Santiago to Santo DomingoDiscover last-minute flight deals from Santiago to Santo Domingo. Data last updated 10 October 2026 and is based on user searches.
Discover last-minute flight deals from Santiago to Santo Domingo. Data last updated 10 October 2026 and is based on user searches.
Sun 11/103:15 a.m. -
1 stop24h 10m
Tue 27/105:55 a.m. -
1 stop23h 00m
Deal found 5/10C$ 1,104
Sun 11/101:07 a.m. -
1 stop26h 18m
Mon 19/1012:42 p.m. -
1 stop10h 40m
Deal found 5/10C$ 1,136
Tue 13/103:57 a.m. -
1 stop19h 59m
Wed 21/108:47 a.m. -
1 stop10h 45m
Deal found 9/10C$ 1,025
Fri 16/105:00 a.m. -
1 stop11h 45m
Fri 23/108:55 a.m. -
1 stop14h 00m
Deal found 7/10C$ 1,152
Wed 21/105:22 a.m. -
1 stop18h 34m
Wed 28/102:25 p.m. -
1 stop14h 30m
Deal found 5/10C$ 921
Fri 23/1012:23 p.m. -
1 stop24h 18m
Fri 30/108:57 a.m. -
1 stop14h 25m
Deal found 6/10C$ 850
Fri 23/105:00 a.m. -
1 stop11h 45m
Fri 30/108:55 a.m. -
1 stop14h 00m
Deal found 8/10C$ 1,067
Fri 23/101:07 a.m. -
1 stop11h 34m
Sat 31/1012:12 p.m. -
1 stop10h 27m
Deal found 8/10C$ 1,099
Sun 25/105:22 a.m. -
1 stop13h 45m
Sun 1/115:55 a.m. -
1 stop17h 24m
Deal found 8/10C$ 954
Thu 26/111:22 a.m. -
1 stop22h 36m
Fri 8/112:42 p.m. -
1 stop13h 11m
Deal found 8/10C$ 817
Fri 27/111:22 a.m. -
1 stop11h 23m
Sat 28/117:06 p.m. -
1 stop27h 30m
Deal found 9/10C$ 998
Sun 29/115:07 a.m. -
1 stop18h 51m
Sun 6/125:53 a.m. -
1 stop17h 25m
Deal found 8/10C$ 966
One-way flights from Santiago to Santo DomingoSearch for one-way flight options from Santiago to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated 10 October 2026.
Search for one-way flight options from Santiago to Santo Domingo. Find affordable one-way fares based on user searches. Data last updated 10 October 2026.
Sat 7/119:25 a.m. -
1 stop13h 15m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 5/10C$ 429
Wed 25/115:00 a.m. -
1 stop12h 20m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 8/10C$ 494
Fri 11/1212:20 p.m. -
1 stop23h 42m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 9/10C$ 517
Mon 28/1212:20 p.m. -
1 stop24h 22m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 8/10C$ 550
Fri 23/105:00 a.m. -
1 stop11h 45m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 9/10C$ 551
Sun 27/1212:20 p.m. -
1 stop28h 53m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 6/10C$ 594
Fri 16/105:00 a.m. -
1 stop11h 45m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 5/10C$ 637
Sun 18/103:15 a.m. -
1 stop24h 10m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 5/10C$ 641
Thu 15/1012:23 p.m. -
1 stop11h 33m
Wed 31/1212:00 a.m. -
Nonstop0h 00m
Deal found 5/10C$ 699
Find flight deals from Santiago to Santo Domingo
Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Santo Domingo (SDQ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 10 October 2026.
Cheapflights Fare Finder
Customize your flight search to find flights from Santiago to Santo Domingo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated 10 October 2026.
Use the filters below to find and compare flights from Santiago to Santo Domingo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Mon 21/12
6:00 a.m.-4:45 p.m.
1 stop11h 45m
Santo Domingo Las Americas
Wed 31/12
12:00 a.m.-1:30 a.m.
Nonstop0h 00m
C$ 447
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Sat 7/11
9:25 a.m.-9:40 p.m.
1 stop13h 15m
Santo Domingo Las Americas
Wed 31/12
12:00 a.m.-1:30 a.m.
Nonstop0h 00m
C$ 447
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Fri 11/12
12:20 p.m.-11:02 a.m.
1 stop23h 42m
Santo Domingo Las Americas
Wed 31/12
12:00 a.m.-1:30 a.m.
Nonstop0h 00m
C$ 517
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Wed 28/10
5:22 a.m.-2:11 a.m.
1 stop21h 49m
Santo Domingo Las Americas
Wed 31/12
12:00 a.m.-1:30 a.m.
Nonstop0h 00m
C$ 517
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Wed 24/3
4:06 p.m.-1:29 p.m.
1 stop22h 23m
Santo Domingo Las Americas
Wed 31/12
12:00 a.m.-1:30 a.m.
Nonstop0h 00m
C$ 517
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Mon 23/11
12:15 p.m.-1:10 p.m.
1 stop25h 55m
Santo Domingo Las Americas
Wed 31/12
12:00 a.m.-1:30 a.m.
Nonstop0h 00m
C$ 517
Quickest round-trip
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Thu 25/3
12:30 p.m.-10:22 p.m.
1 stop10h 52m
Santo Domingo Las Americas
Wed 31/12
12:00 a.m.-1:30 a.m.
Nonstop0h 00m
C$ 517
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Fri 23/10
12:23 p.m.-11:41 a.m.
1 stop24h 18m
Santo Domingo Las Americas
Wed 31/12
12:00 a.m.-1:30 a.m.
Nonstop0h 00m
C$ 517
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Wed 9/12
1:27 a.m.-11:02 a.m.
1 stop10h 35m
Santo Domingo Las Americas
Thu 24/12
8:55 a.m.-11:35 p.m.
1 stop13h 40m
C$ 817
SantiagoSanto Domingo
SCL Santiago Arturo Merino Benitez - SDQ Santo Domingo Las Americas
SCLSDQ
Santiago Arturo Merino Benitez
Sat 12/12
12:20 p.m.-2:08 a.m.
1 stop14h 48m
Santo Domingo Las Americas
Sat 26/12
8:55 a.m.-8:11 p.m.
1 stop10h 16m
C$ 817
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Santiago to Santo Domingo
Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Santiago with our price prediction graph.
SCL-SDQ
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santiago to Santo Domingo
How far ahead should I book a flight from Santiago to Santo Domingo?
Booking 41 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Santo Domingo. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from Santiago to Santo Domingo?
Currently, November is the cheapest month in which you can book a flight from Santiago to Santo Domingo (average of C$ 785). Flying from Santiago to Santo Domingo in January is currently the most expensive (average of C$ 1,014). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Santiago to Santo Domingo?
Airfare is typical for this route at the moment.
Santiago to Santo Domingo flights typically cost between C$ 758 and C$ 940 in December.The cheapest round-trip price found within the last 5 days was C$ 817 on Copa Airlines (9 Dec-24 Dec).
Related info for your journey
Find useful and relevant information for your journey from Santiago to Santo Domingo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Santo Domingo flight routes
Complete your trip
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Direct flights to Dominican Republic
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Santiago and Santo Domingo flights
Browse other Santiago and Santo Domingo flight options. Last updated on 10 October 2026.
Other flights from Santiago
Browse through other flights departing from Santiago. Flights are based on user searches made on Cheapflights and were last updated on 10 October 2026.
Popular flight searches
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Other flights to Santo Domingo
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Fly with Cheapflights
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How does Cheapflights help users find flights from Santiago to Santo Domingo?
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Why should you use Cheapflights to find cheap flight tickets from Santiago to Santo Domingo?
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Can Cheapflights find flights from Santiago to Santo Domingo with no change fees?
Yes! Cheapflights helps users easily find flights from Santiago to Santo Domingo with no change fees.
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Of course! You can now track prices for flights from Santiago to Santo Domingo and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.