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Cheap flights from Madrid, Spain to Santiago from C$ 682

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/11. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
15 Oct — 22 Oct1
1 adult
1 adult, Economy

Cheap flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 15 September 2025.

Round-trip from

C$ 1,196

One-way from

C$ 682

Popular in

December

Cheapest in

March

Average price

C$ 1,469
Delta
  • Delta
  • 29/10-4/11
  • 4 total stops
  • 69h 40m total
  • Madrid to Santiago
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United Airlines
  • United Airlines
  • 19/11
  • 2 total stops
  • 30h 55m total
  • Madrid to Santiago
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Highest demand for flights based on searches. 5% potential increase in price (C$ 112 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease (C$ 52 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Madrid to Santiago

Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Wed 29/106:00 a.m.MAD - SCL
2 stops29h 40mDelta
Tue 4/1111:10 p.m.SCL - MAD
2 stops40h 00mDelta
Deal found 13/9C$ 1,196
Mon 15/910:05 a.m.MAD - SCL
2 stops25h 55mDelta
Mon 22/99:40 p.m.SCL - MAD
2 stops32h 40mDelta
Deal found 14/9C$ 1,197
Sun 14/910:05 a.m.MAD - SCL
1 stop25h 55mDelta
Fri 26/99:40 p.m.SCL - MAD
1 stop30h 55mDelta
Deal found 13/9C$ 1,200
Fri 31/106:00 a.m.MAD - SCL
2 stops29h 40mDelta
Tue 11/1111:10 p.m.SCL - MAD
2 stops36h 10mDelta
Deal found 14/9C$ 1,211
Sat 27/1211:15 a.m.MAD - SCL
1 stop22h 55mDelta
Thu 22/111:15 p.m.SCL - MAD
1 stop29h 45mDelta
Deal found 14/9C$ 1,218
Thu 23/106:00 a.m.MAD - SCL
2 stops30h 00mDelta
Thu 6/1111:10 p.m.SCL - MAD
1 stop30h 05mDelta
Deal found 13/9C$ 1,233
Mon 24/1111:15 a.m.MAD - SCL
1 stop24h 25mDelta
Fri 28/1111:10 p.m.SCL - MAD
1 stop30h 05mDelta
Deal found 13/9C$ 1,235
Mon 10/116:00 a.m.MAD - SCL
2 stops29h 40mDelta
Mon 24/1111:10 p.m.SCL - MAD
2 stops36h 55mDelta
Deal found 13/9C$ 1,240
Wed 26/1112:55 p.m.MAD - SCL
Nonstop13h 20mIberia
Tue 10/211:55 p.m.SCL - MAD
Nonstop12h 40mIberia
Deal found 14/9C$ 1,242
Tue 4/1111:15 a.m.MAD - SCL
1 stop24h 25mDelta
Tue 18/1111:10 p.m.SCL - MAD
2 stops32h 20mDelta
Deal found 13/9C$ 1,244
Wed 19/116:00 a.m.MAD - SCL
2 stops29h 40mDelta
Wed 3/1211:10 p.m.SCL - MAD
1 stop30h 05mDelta
Deal found 14/9C$ 1,248
Thu 2/1012:20 p.m.MAD - SCL
2 stops23h 40mDelta
Mon 20/109:40 p.m.SCL - MAD
2 stops29h 10mDelta
Deal found 14/9C$ 1,251

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 15 September 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Madrid

Fly to

Santiago

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 6/11

11:15 a.m.-7:40 a.m.

1 stop24h 25m

Santiago Arturo Merino Benitez

Tue 2/12

11:10 p.m.-9:15 a.m.

1 stop30h 05m

C$ 1,200

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 4/11

11:15 a.m.-7:40 a.m.

1 stop24h 25m

Santiago Arturo Merino Benitez

Sun 16/11

11:10 p.m.-9:15 a.m.

1 stop30h 05m

C$ 1,200

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 29/1

11:15 a.m.-8:50 a.m.

2 stops49h 35m

Santiago Arturo Merino Benitez

Fri 6/3

10:45 p.m.-8:05 a.m.

2 stops53h 20m

C$ 1,201

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sat 27/12

11:15 a.m.-6:10 a.m.

1 stop22h 55m

Santiago Arturo Merino Benitez

Thu 22/1

11:15 p.m.-9:00 a.m.

1 stop29h 45m

C$ 1,218

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 5/2

6:00 a.m.-7:00 a.m.

2 stops29h 00m

Santiago Arturo Merino Benitez

Mon 23/2

11:15 p.m.-10:15 a.m.

2 stops31h 00m

C$ 1,240

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 4/11

10:00 a.m.-7:40 a.m.

2 stops25h 40m

Santiago Arturo Merino Benitez

Tue 18/11

11:10 p.m.-11:30 a.m.

2 stops32h 20m

C$ 1,244

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 19/11

6:00 a.m.-7:40 a.m.

2 stops29h 40m

Santiago Arturo Merino Benitez

Wed 3/12

11:10 p.m.-9:15 a.m.

1 stop30h 05m

C$ 1,248

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 8/2

11:15 a.m.-8:50 a.m.

2 stops49h 35m

Santiago Arturo Merino Benitez

Sun 1/3

10:45 p.m.-9:15 a.m.

2 stops30h 30m

C$ 1,283

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 6/2

7:05 a.m.-7:00 a.m.

2 stops27h 55m

Santiago Arturo Merino Benitez

Sun 1/3

11:15 p.m.-7:10 p.m.

2 stops39h 55m

C$ 1,293

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 19/11

5:55 a.m.-8:50 a.m.

2 stops30h 55m

C$ 682

Flights are sorted by cheapest round-trip flights first.

Deals found on 14/9

Showing 1-10 of 19 results
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Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santiago. Price data was last updated on 12 September 2025.

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, August is the cheapest month in which you can book a flight from Madrid to Santiago (average of C$ 605). Flying from Madrid to Santiago in December is currently the most expensive (average of C$ 881). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 15 September 2025.

When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Madrid to Santiago?

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Madrid to Santiago flight route?

    The Madrid Barajas to Santiago Arturo Merino Benitez flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 24h 25m. Delta provides one of the quickest options available for as low as C$ 1,200. The distance from Madrid to Santiago is about 10712 km. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most reliable airlines from Madrid to Santiago?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Madrid to Santiago on time: Finnair (90%), Japan Airlines (85%), EL AL (85%).

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, August is the cheapest month in which you can book a flight from Madrid to Santiago (average of C$ 605). Flying from Madrid to Santiago in December is currently the most expensive (average of C$ 881). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?

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Can Cheapflights find flights from Madrid to Santiago with no change fees?

Yes, we can. To see specific flights from Madrid to Santiago with no change fees, users can toggle flexible booking options after using the search form above to find flights.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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