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Cheap flights from Madrid, Spain to Santiago from C$ 790

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/2. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
29 Nov — 6 Dec1
1 adult
1 adult, Economy, 0 bags

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Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 October 2025.

Tue 23/1211:15 a.m.MAD - SCL
1 stop22h 55mDelta
Mon 12/111:10 p.m.SCL - MAD
2 stops34h 10mDelta
Deal found 29/10C$ 1,160
Mon 8/1211:15 a.m.MAD - SCL
1 stop24h 25mDelta
Sun 15/311:15 p.m.SCL - MAD
2 stops38h 25mDelta
Deal found 30/10C$ 1,165
Sun 23/1111:15 a.m.MAD - SCL
1 stop24h 25mDelta
Sat 6/1211:10 p.m.SCL - MAD
2 stops32h 20mDelta
Deal found 29/10C$ 1,167
Fri 5/126:00 a.m.MAD - SCL
2 stops29h 40mDelta
Tue 20/111:10 p.m.SCL - MAD
2 stops28h 50mDelta
Deal found 30/10C$ 1,172
Wed 26/116:00 a.m.MAD - SCL
2 stops29h 40mDelta
Wed 3/1211:10 p.m.SCL - MAD
2 stops28h 50mDelta
Deal found 29/10C$ 1,174
Thu 27/116:00 a.m.MAD - SCL
2 stops29h 40mDelta
Thu 4/129:30 p.m.SCL - MAD
2 stops30h 30mDelta
Deal found 30/10C$ 1,187
Sat 22/1112:35 p.m.MAD - SCL
2 stops47h 05mDelta
Thu 4/1211:10 p.m.SCL - MAD
1 stop30h 05mDelta
Deal found 30/10C$ 1,190
Wed 12/1111:15 a.m.MAD - SCL
1 stop24h 25mDelta
Tue 10/311:15 p.m.SCL - MAD
2 stops32h 55mDelta
Deal found 30/10C$ 1,195
Mon 8/1211:15 a.m.MAD - SCL
1 stop24h 25mDelta
Wed 11/211:10 p.m.SCL - MAD
2 stops31h 05mDelta
Deal found 29/10C$ 1,198
Sun 23/116:00 a.m.MAD - SCL
2 stops29h 40mDelta
Sun 7/1211:10 p.m.SCL - MAD
2 stops32h 20mDelta
Deal found 29/10C$ 1,201
Mon 24/1111:15 a.m.MAD - SCL
1 stop24h 25mDelta
Sun 7/1211:10 p.m.SCL - MAD
1 stop30h 05mDelta
Deal found 30/10C$ 1,202

Cheap flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 October 2025.

Round-trip from

C$ 1,153

One-way from

C$ 790

Popular in

December

Cheapest in

March

Average price

C$ 1,497
Delta
  • Delta
  • 11/11-17/11
  • 4 total stops
  • 57h 00m total
  • Madrid to Santiago
Search Deals
Avianca
  • Avianca
  • 1/2
  • 1 total stop
  • 26h 55m total
  • Madrid to Santiago
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (C$ 112 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (C$ 54 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 30 October 2025.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Madrid

Fly to

Santiago

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 11/11

7:30 a.m.-7:40 a.m.

2 stops28h 10m

Santiago Arturo Merino Benitez

Mon 17/11

11:10 p.m.-8:00 a.m.

2 stops28h 50m

C$ 1,153

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 18/1

10:00 a.m.-7:40 a.m.

2 stops25h 40m

Santiago Arturo Merino Benitez

Tue 3/2

11:10 p.m.-9:15 a.m.

1 stop30h 05m

C$ 1,204

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 19/11

6:00 a.m.-7:40 a.m.

2 stops29h 40m

Santiago Arturo Merino Benitez

Sun 7/12

11:10 p.m.-7:10 p.m.

2 stops40h 00m

C$ 1,215

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 30/12

10:00 a.m.-6:10 a.m.

2 stops48h 10m

Santiago Arturo Merino Benitez

Sat 24/1

11:10 p.m.-8:00 a.m.

2 stops28h 50m

C$ 1,219

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 5/12

10:00 a.m.-7:40 a.m.

2 stops25h 40m

Santiago Arturo Merino Benitez

Wed 21/1

11:10 p.m.-8:00 a.m.

2 stops28h 50m

C$ 1,222

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 23/11

11:15 a.m.-7:40 a.m.

1 stop24h 25m

Santiago Arturo Merino Benitez

Thu 22/1

9:30 p.m.-9:15 a.m.

1 stop31h 45m

C$ 1,222

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 13/11

11:15 a.m.-7:40 a.m.

1 stop24h 25m

Santiago Arturo Merino Benitez

Mon 17/11

11:10 p.m.-8:00 a.m.

2 stops28h 50m

C$ 1,237

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 31/3

12:20 p.m.-8:00 a.m.

2 stops24h 40m

Santiago Arturo Merino Benitez

Tue 21/4

8:40 p.m.-7:50 a.m.

2 stops29h 10m

C$ 1,254

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 4/12

11:15 a.m.-7:40 a.m.

1 stop24h 25m

Santiago Arturo Merino Benitez

Sat 27/12

9:30 p.m.-4:05 p.m.

2 stops38h 35m

C$ 1,283

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 12/11

10:00 a.m.-7:40 a.m.

2 stops49h 40m

Santiago Arturo Merino Benitez

Sun 8/3

11:15 p.m.-7:00 a.m.

2 stops27h 45m

C$ 1,301

Flights are sorted by cheapest round-trip flights first.

Deals found on 30/10

Showing 1-10 of 22 results
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Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santiago. Price data was last updated on 24 October 2025.

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 88 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, January is the cheapest month in which you can book a flight from Madrid to Santiago (average of C$ 797). Flying from Madrid to Santiago in July is currently the most expensive (average of C$ 1,240). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 October 2025.

When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Madrid to Santiago?

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Madrid to Santiago flight route?

    The Madrid Barajas to Santiago Arturo Merino Benitez flight path was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 28h 10m. Delta provides one of the quickest options available for as low as C$ 1,153. The distance from Madrid to Santiago is about 10712 km.

  • What are the cheapest airlines to fly from Madrid to Santiago one-way?

    For one-way options, check prices for United Airlines. According to our data, you can fly for as low as C$ 873. Users have also found prices from C$ 948 and C$ 973 on Avianca and Iberia, respectively.

  • What are the most reliable airlines from Madrid to Santiago?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Madrid to Santiago on time: Japan Airlines (97%), Finnair (97%), EL AL (97%).

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, January is the cheapest month in which you can book a flight from Madrid to Santiago (average of C$ 797). Flying from Madrid to Santiago in July is currently the most expensive (average of C$ 1,240). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?

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Can Cheapflights find flights from Madrid to Santiago with no change fees?

Yes, we can. To see specific flights from Madrid to Santiago with no change fees, users can toggle flexible booking options after using the search form above to find flights.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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