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Cheap flights from Madrid, Spain to Santiago from C$ 736

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 15/4. Fares are subject to change and may not be available on all flights or dates of travel.
MAD — SCL
28 Feb — 7 Mar1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Madrid to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Madrid to Santiago
Explore the most affordable flight options available from Madrid to Santiago. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 29 January 2026.

Wed 15/412:45 p.m.
MAD
-
SCL
1 stop24h 30m
Delta
Sun 26/48:40 p.m.
SCL
-
MAD
1 stop33h 35m
Delta
Deal found 27/1C$ 1,125
Tue 3/211:15 a.m.
MAD
-
SCL
1 stop24h 25m
Delta
Mon 23/211:10 p.m.
SCL
-
MAD
1 stop30h 05m
Delta
Deal found 27/1C$ 1,127
Tue 3/211:15 a.m.
MAD
-
SCL
1 stop24h 25m
Delta
Thu 19/211:10 p.m.
SCL
-
MAD
1 stop30h 05m
Delta
Deal found 28/1C$ 1,132
Wed 15/42:35 p.m.
MAD
-
SCL
2 stops46h 40m
Delta
Tue 28/48:40 p.m.
SCL
-
MAD
2 stops31h 15m
Delta
Deal found 28/1C$ 1,135
Tue 3/210:00 a.m.
MAD
-
SCL
2 stops25h 40m
Delta
Sun 15/211:10 p.m.
SCL
-
MAD
2 stops52h 50m
Delta
Deal found 29/1C$ 1,136
Wed 16/99:50 a.m.
MAD
-
SCL
1 stop27h 25m
Delta
Sun 18/108:40 p.m.
SCL
-
MAD
1 stop34h 35m
Delta
Deal found 29/1C$ 1,139
Sun 1/210:00 a.m.
MAD
-
SCL
2 stops25h 40m
Delta
Sun 8/211:10 p.m.
SCL
-
MAD
2 stops38h 30m
Delta
Deal found 27/1C$ 1,154
Mon 2/210:00 a.m.
MAD
-
SCL
2 stops25h 40m
Delta
Sun 15/211:10 p.m.
SCL
-
MAD
2 stops38h 30m
Delta
Deal found 27/1C$ 1,159
Wed 4/1111:50 a.m.
MAD
-
SCL
1 stop31h 35m
British Airways
Fri 13/111:05 p.m.
SCL
-
MAD
1 stop18h 50m
British Airways
Deal found 27/1C$ 1,169
Thu 22/1011:50 a.m.
MAD
-
SCL
1 stop28h 30m
British Airways
Sun 1/111:05 p.m.
SCL
-
MAD
1 stop23h 50m
British Airways
Deal found 27/1C$ 1,173
Tue 3/36:00 a.m.
MAD
-
SCL
2 stops29h 40m
Delta
Tue 26/58:40 p.m.
SCL
-
MAD
2 stops27h 40m
Delta
Deal found 27/1C$ 1,176

Find flight deals from Madrid to Santiago

Discover tips and strategies to find the most affordable flight options for your journey from Madrid (MAD) to Santiago (SCL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 29 January 2026.

Round-trip from

C$ 1,125

One-way from

C$ 736

Popular in

July

Cheapest in

March

Average price

C$ 1,405
Delta
  • Delta
  • 16/4-26/4
  • 2 total stops
  • 58h 05m total
  • Madrid to Santiago
Search Deals
Iberia
  • Iberia
  • 15/4
  • Nonstop
  • 13h 20m total
  • Madrid to Santiago
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (C$ 261 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (C$ 45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madrid to Santiago that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 29 January 2026.
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Madrid

Fly to

Santiago

Route

Depart

Return

Price

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 13/4

2:35 p.m.-7:15 a.m.

2 stops46h 40m

Santiago Arturo Merino Benitez

Sun 26/4

8:40 p.m.-9:55 a.m.

2 stops55h 15m

C$ 1,127

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Mon 13/4

2:35 p.m.-7:15 a.m.

2 stops46h 40m

Santiago Arturo Merino Benitez

Tue 28/4

8:40 p.m.-9:55 a.m.

2 stops31h 15m

C$ 1,135

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 16/4

12:45 p.m.-7:15 a.m.

1 stop24h 30m

Santiago Arturo Merino Benitez

Wed 29/4

8:40 p.m.-9:55 a.m.

2 stops55h 15m

C$ 1,135

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Wed 29/4

12:45 p.m.-7:15 a.m.

1 stop24h 30m

Santiago Arturo Merino Benitez

Sun 7/6

8:40 p.m.-6:20 a.m.

2 stops51h 40m

C$ 1,208

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Tue 14/4

2:35 p.m.-7:15 a.m.

2 stops46h 40m

Santiago Arturo Merino Benitez

Mon 27/4

8:40 p.m.-9:55 a.m.

2 stops31h 15m

C$ 1,208

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 12/3

6:00 a.m.-7:50 a.m.

2 stops29h 50m

Santiago Arturo Merino Benitez

Mon 16/3

9:45 p.m.-9:15 a.m.

2 stops31h 30m

C$ 1,241

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 6/3

11:15 a.m.-8:50 a.m.

2 stops25h 35m

Santiago Arturo Merino Benitez

Mon 16/3

9:45 p.m.-9:15 a.m.

2 stops31h 30m

C$ 1,272

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Sun 26/4

2:35 p.m.-7:15 a.m.

2 stops46h 40m

Santiago Arturo Merino Benitez

Sun 7/6

8:40 p.m.-12:15 p.m.

1 stop33h 35m

C$ 1,288

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Fri 17/4

12:45 p.m.-7:15 a.m.

1 stop24h 30m

Santiago Arturo Merino Benitez

Sun 26/4

8:40 p.m.-12:15 p.m.

1 stop33h 35m

C$ 1,294

MadridSantiago

MAD - SCL

MADSCL

Madrid Barajas

Thu 19/3

10:05 a.m.-7:40 a.m.

1 stop25h 35m

Santiago Arturo Merino Benitez

Wed 8/4

8:40 p.m.-12:15 p.m.

1 stop33h 35m

C$ 1,296

Flights are sorted by cheapest round-trip flights first.

Deals found on 27/1

Showing 1-10 of 22 results
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Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

Use this chart to determine the optimal time to book a round-trip flight from Madrid to Santiago. Price data was last updated on 23 January 2026.

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 72 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of C$ 701). Flying from Madrid to Santiago in July is currently the most expensive (average of C$ 1,301). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

Find hourly flight availability from Madrid to Santiago. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 29 January 2026.

When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Madrid to Santiago?

Related info for your journey

Find useful and relevant information for your journey from Madrid to Santiago. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Madrid to Santiago flight route?

    The Madrid Barajas to Santiago Arturo Merino Benitez flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 24h 30m. Delta provides one of the quickest options available for as low as C$ 1,125. The distance from Madrid to Santiago is about 10712 km.

  • What are the most reliable airlines from Madrid to Santiago?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Madrid to Santiago on time: Japan Airlines (88%), Finnair (88%), EL AL (88%).

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, March is the cheapest month in which you can book a flight from Madrid to Santiago (average of C$ 701). Flying from Madrid to Santiago in July is currently the most expensive (average of C$ 1,301). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Viña del Mar

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Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?

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Yes, we can. To see specific flights from Madrid to Santiago with no change fees, users can toggle flexible booking options after using the search form above to find flights.

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Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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