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Cheap flights from Santiago to Panama City from C$ 385

SCL — PTY
10 Oct — 17 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Panama City

Wed 28/1012:23 p.m. -
Nonstop6h 48m
Sun 1/113:08 p.m. -
Nonstop6h 28m
Deal found 9/9C$ 805
Sat 5/125:07 a.m. -
Nonstop6h 56m
Sat 12/1211:48 a.m. -
Nonstop6h 23m
Deal found 6/9C$ 807
Sat 5/123:19 a.m. -
Nonstop6h 57m
Sun 28/29:24 p.m. -
Nonstop6h 32m
Deal found 5/9C$ 827
Fri 30/1012:23 p.m. -
Nonstop6h 48m
Tue 10/113:51 p.m. -
Nonstop6h 28m
Deal found 10/9C$ 844
Sat 24/104:20 p.m. -
1 stop10h 15m
Sat 31/1010:05 a.m. -
1 stop17h 40m
Deal found 9/9C$ 855
Wed 28/102:10 a.m. -
1 stop15h 05m
Wed 4/1110:05 a.m. -
1 stop17h 40m
Deal found 8/9C$ 856
Tue 22/91:06 a.m. -
Nonstop6h 49m
Sat 31/1011:48 a.m. -
Nonstop6h 31m
Deal found 6/9C$ 862
Tue 29/93:14 a.m. -
Nonstop6h 49m
Fri 30/1011:48 a.m. -
Nonstop6h 31m
Deal found 8/9C$ 877
Thu 12/113:48 a.m. -
Nonstop6h 57m
Mon 23/113:51 p.m. -
Nonstop6h 28m
Deal found 7/9C$ 882
Mon 14/93:14 a.m. -
Nonstop6h 49m
Tue 15/123:51 p.m. -
Nonstop6h 27m
Deal found 6/9C$ 889
Mon 14/123:48 a.m. -
Nonstop6h 57m
Tue 22/127:11 p.m. -
Nonstop6h 32m
Deal found 7/9C$ 903

Find flight deals from Santiago to Panama City

Round-trip from

C$ 805

One-way from

C$ 385

Popular in

September

Cheapest in

November

Average price

C$ 918

Good one-way deal

C$ 560 or less
Copa Airlines
  • Copa Airlines
  • 28/10-1/11
  • Nonstop
  • 13h 16m total
  • Santiago to Panama City
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Copa Airlines
  • Copa Airlines
  • 1/11-31/12
  • Nonstop
  • 6h 56m total
  • Santiago to Panama City
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Highest demand for flights based on searches. 8% potential increase in price (C$ 98 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 18 potential savings vs. average RT price).
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Average for round-trip flights in September 2026
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Price to beat on a one-way flight from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Tue 6/10

7:40 a.m.-2:15 p.m.

1 stop8h 35m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 438

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Tue 15/9

4:20 p.m.-12:35 a.m.

1 stop10h 15m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 438

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Wed 27/1

9:02 p.m.-9:10 a.m.

2 stops14h 08m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 513

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Sat 23/1

7:30 a.m.-3:15 p.m.

1 stop9h 45m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 525

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Wed 27/1

4:15 p.m.-1:20 a.m.

1 stop11h 05m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 525

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Mon 7/12

1:07 a.m.-5:59 a.m.

Nonstop6h 52m

Panama City Tocumen Intl

Sat 12/12

7:11 p.m.-3:43 a.m.

Nonstop6h 32m

C$ 807

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Fri 23/10

12:23 p.m.-5:11 p.m.

Nonstop6h 48m

Panama City Tocumen Intl

Wed 28/10

3:51 p.m.-12:22 a.m.

Nonstop6h 31m

C$ 844

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Mon 2/11

1:02 a.m.-5:59 a.m.

Nonstop6h 57m

Panama City Tocumen Intl

Thu 12/11

11:48 a.m.-8:15 p.m.

Nonstop6h 27m

C$ 844

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Wed 7/10

3:15 a.m.-8:03 a.m.

Nonstop6h 48m

Panama City Tocumen Intl

Thu 22/10

9:39 p.m.-6:10 a.m.

Nonstop6h 31m

C$ 882

SantiagoPanama City

SCL Santiago Arturo Merino Benitez - PTY Panama City Tocumen Intl

SCLPTY

Santiago Arturo Merino Benitez

Tue 20/10

1:44 a.m.-6:32 a.m.

Nonstop6h 48m

Panama City Tocumen Intl

Sun 25/10

3:51 p.m.-12:22 a.m.

Nonstop6h 31m

C$ 882

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/9

Showing 1-10 of 20 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santiago with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Panama City

How far ahead should I book a flight from Santiago to Panama City?

The best time to book flights from Santiago to Panama City is 10 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Panama City?

Currently, November is the cheapest month in which you can book a flight from Santiago to Panama City (average of C$ 652). Flying from Santiago to Panama City in September is currently the most expensive (average of C$ 918). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to PTY?

When flying from Santiago to Panama City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Santiago to Panama City?

Airfare is below average for this route at the moment.

Santiago to Panama City flights typically cost between C$ 851 and C$ 1,009 in October.
The cheapest round-trip price found within the last 5 days was C$ 805 on Copa Airlines (28 Oct-1 Nov).

Related info for your journey

  • How popular is this Santiago to Panama City flight route?

    Within the past month, 19 users have taken a look at flights from Santiago Arturo Merino Benitez to Panama City Tocumen Intl.

  • How long is the flight from Santiago to Panama City?

    For as low as C$ 807, Copa Airlines can have you in Panama City from Santiago in 6h 52m. The distance from Santiago to Panama City is about 4806 km. All flights are typically direct.

  • What are the most reliable airlines from Santiago to Panama City?

    Before booking your flight to Panama City from Santiago, check out the most reliable airlines to get you to your destination on time: KLM (90%), Copa Airlines (83%), United Airlines( 82%).

  • Can I find deals for flights from Santiago to Panama City that include hotel bookings?

    Yes. In addition to deals on Santiago to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Panama City.

  • Can I find deals for business class flights from Santiago to Panama City?

    Yes. Cheapflights offers flight deals from Santiago to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Panama City?

    Currently, November is the cheapest month in which you can book a flight from Santiago to Panama City (average of C$ 652). Flying from Santiago to Panama City in September is currently the most expensive (average of C$ 918). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Certainly. Search results for flights to Panama City from Santiago shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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