Cheap flights from Madrid, Spain to Santiago from C$ 801

MAD — SCL
29 Nov — 6 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Madrid to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Madrid to Santiago

Thu 12/119:20 a.m. -
2 stops26h 20m
Wed 25/1111:10 p.m. -
2 stops28h 10m
Deal found 30/10C$ 1,260
Thu 26/113:50 p.m. -
1 stop22h 00m
Wed 9/1212:50 p.m. -
Nonstop12h 35m
Deal found 30/10C$ 1,292
Thu 29/106:05 a.m. -
2 stops29h 35m
Sun 8/1111:10 p.m. -
2 stops28h 10m
Deal found 28/10C$ 1,308
Mon 7/129:20 a.m. -
2 stops26h 20m
Tue 19/111:00 p.m. -
2 stops28h 20m
Deal found 29/10C$ 1,340
Sat 14/119:20 a.m. -
2 stops50h 20m
Thu 26/1111:10 p.m. -
2 stops28h 10m
Deal found 29/10C$ 1,341
Fri 13/119:20 a.m. -
2 stops26h 20m
Sat 21/1111:10 p.m. -
2 stops28h 10m
Deal found 30/10C$ 1,343

Find flight deals from Madrid to Santiago

Round-trip from

C$ 1,243

One-way from

C$ 801

Popular in

July

Cheapest in

May

Average price

C$ 1,659
Avianca
  • Avianca
  • 9/3-6/4
  • 2 total stops
  • 41h 20m total
  • Madrid to Santiago
United Airlines
  • United Airlines
  • 8/2-31/12
  • 2 total stops
  • 30h 45m total
  • Madrid to Santiago
Highest demand for flights based on searches. 11% potential increase in price (C$ 283 potential increase over avg. RT price).
Cheapest flight prices on average. 3% potential price decrease (C$ 65 potential savings vs. average RT price).
Average for round-trip flights in October 2026

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Madrid to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Tue 8/12

11:15 a.m.-8:50 a.m.

2 stops49h 35m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 923

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Thu 5/11

11:15 a.m.-8:50 a.m.

2 stops49h 35m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 930

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Sat 6/3

8:00 p.m.-1:05 a.m.

2 stops57h 05m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 947
Quickest round-trip

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Tue 24/11

1:00 p.m.-10:20 p.m.

Nonstop13h 20m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 1,035

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Thu 19/11

1:00 p.m.-10:20 p.m.

Nonstop13h 20m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 1,035

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Sun 3/1

11:59 p.m.-9:20 a.m.

Nonstop13h 21m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 1,045

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Fri 13/11

9:20 a.m.-7:40 a.m.

2 stops26h 20m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 1,080

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Wed 18/11

12:20 p.m.-7:40 a.m.

1 stop23h 20m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 1,080

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Sat 7/11

12:20 p.m.-7:40 a.m.

1 stop23h 20m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 1,080

MadridSantiago

MAD Madrid Barajas - SCL Santiago Arturo Merino Benitez

MADSCL

Madrid Barajas

Tue 12/1

1:55 p.m.-7:40 a.m.

1 stop21h 45m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-4:00 a.m.

Nonstop0h 00m

C$ 1,080

Flights are sorted by cheapest round-trip flights first.

Deals found on 29/10

Showing 1-10 of 21 resultsSorted by cheapest first
1
2
3

Best time to book a flight from Madrid to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Madrid with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Madrid to Santiago

How far ahead should I book a flight from Madrid to Santiago?

The price you pay for your flight from Madrid to Santiago may vary depending on when you book. For the best chance of a lower fare, look to book 51 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Madrid to Santiago?

Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of C$ 1,278). Flying from Madrid to Santiago in July is currently the most expensive (average of C$ 2,059). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MAD to SCL?

When flying from Madrid to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Madrid to Santiago?

Airfare is typical for this route at the moment.

Madrid to Santiago flights typically cost between C$ 1,220 and C$ 1,722 in March.
The cheapest round-trip price found within the last 5 days was C$ 1,243 on Avianca (9 Mar-6 Apr).

Related info for your journey

  • How popular is this Madrid to Santiago flight route?

  • How long is the flight from Madrid to Santiago?

    A quick flight from Madrid to Santiago can take about 13h 20m. Delta provides one of the quickest options available for as low as C$ 1,351. The distance from Madrid to Santiago is about 10712 km. Both multi-stop and direct flights can be found to your destination and back.

  • What are the most reliable airlines from Madrid to Santiago?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Madrid to Santiago on time: Japan Airlines (90%), Finnair (90%), EL AL (90%).

  • Can I find deals for flights from Madrid to Santiago that include hotel bookings?

    Yes. In addition to deals on Madrid to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madrid to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madrid to Santiago.

  • Can I find deals for business class flights from Madrid to Santiago?

    Yes. Cheapflights offers flight deals from Madrid to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madrid to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Madrid to Santiago (average of C$ 1,278). Flying from Madrid to Santiago in July is currently the most expensive (average of C$ 2,059). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Valparaíso
Viña del Mar

Browse thousands of different options on Cheapflights for your next trip

Fly with Cheapflights

How does Cheapflights help users find flights from Madrid to Santiago?

Cheapflights goes through 900+ travel sites to look for the best flight deals for flights from Madrid to Santiago. Too many options? Cheapflights also provides filters for things like airlines, price ranges, and number of stops to help you make a decision easily.

Why should you use Cheapflights to find cheap flight tickets from Madrid to Santiago?

Cheapflights simply makes it quick and affordable to book flights from Madrid to Santiago by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Madrid to Santiago with no change fees?

Yes, we can. To see specific flights from Madrid to Santiago with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Madrid to Santiago become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.