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Cheap flights from Buffalo to Missouri from C$ 141

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 20/11. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
29 Nov — 6 Dec1
1 adult
1 adult, Economy, 0 bags

Find flight deals from Buffalo to Missouri

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to Missouri
Explore the most affordable flight options available from Buffalo to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 30 October 2025.

Wed 19/1112:05 p.m.BUF - STL
1 stop6h 20mSouthwest
Wed 26/115:40 a.m.STL - BUF
1 stop5h 20mSouthwest
Deal found 28/10C$ 402
Wed 26/113:20 p.m.BUF - STL
1 stop10h 15mSouthwest
Wed 3/121:15 p.m.STL - BUF
2 stops7h 45mSouthwest
Deal found 29/10C$ 409
Fri 14/119:53 p.m.BUF - MCI
1 stop15h 35mMultiple Airlines
Sun 16/118:28 p.m.MCI - BUF
2 stops16h 09mMultiple Airlines
Deal found 29/10C$ 412
Thu 11/126:12 a.m.BUF - SGF
2 stops10h 11mDelta
Mon 15/124:08 p.m.SGF - BUF
1 stop6h 51mDelta
Deal found 30/10C$ 445
Tue 16/121:50 p.m.BUF - MCI
1 stop4h 35mUnited Airlines
Fri 2/17:40 a.m.MCI - BUF
1 stop4h 44mUnited Airlines
Deal found 30/10C$ 471
Sat 6/126:55 a.m.BUF - STL
1 stop6h 50mSouthwest
Fri 12/122:30 p.m.STL - BUF
2 stops8h 10mSouthwest
Deal found 28/10C$ 473
Fri 12/123:40 p.m.BUF - STL
2 stops8h 30mSouthwest
Sun 14/126:40 a.m.STL - BUF
2 stops8h 40mSouthwest
Deal found 28/10C$ 526
Tue 23/128:40 p.m.BUF - STL
1 stop4h 25mSouthwest
Sat 27/121:15 p.m.STL - BUF
1 stop9h 05mSouthwest
Deal found 29/10C$ 532
Fri 12/123:40 p.m.BUF - STL
2 stops8h 30mSouthwest
Fri 19/126:45 a.m.STL - BUF
2 stops6h 50mSouthwest
Deal found 30/10C$ 582
Fri 14/1112:05 p.m.BUF - STL
1 stop5h 02mDelta
Tue 18/116:40 a.m.STL - BUF
1 stop4h 51mDelta
Deal found 30/10C$ 624
Thu 13/118:10 a.m.BUF - MCI
1 stop8h 55mUnited Airlines
Fri 14/111:47 p.m.MCI - BUF
1 stop8h 05mUnited Airlines
Deal found 30/10C$ 652
Fri 14/1110:50 a.m.BUF - MCI
1 stop4h 31mUnited Airlines
Tue 18/1112:45 p.m.MCI - BUF
2 stops9h 13mUnited Airlines
Deal found 30/10C$ 659

Cheap flight deals from Buffalo to Missouri

Keep the following information in mind while searching for Buffalo to Missouri flight deals. Data was last updated 30 October 2025.

Round-trip from

C$ 402

One-way from

C$ 141

Popular in

January

Cheapest in

September

Average price

C$ 580
Southwest
  • Southwest
  • 19/11-26/11
  • 2 total stops
  • 11h 40m total
  • Buffalo to Missouri
Search Deals
20/11
  • 20/11
  • 1 total stop
  • 25h 23m total
  • Buffalo to Missouri
Search Deals
Highest demand for flights based on searches. 21% potential increase in price (C$ 222 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 10% potential price decrease (C$ 83 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 30 October 2025.
Use the filters below to find and compare flights from Buffalo to Missouri that are best for you.

Fly from

Buffalo

Fly to

Missouri

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 19/11

12:05 p.m.-5:25 p.m.

1 stop6h 20m

Lambert-St Louis

Wed 26/11

5:40 a.m.-12:00 p.m.

1 stop5h 20m

C$ 402

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 26/11

3:20 p.m.-12:35 a.m.

1 stop10h 15m

Lambert-St Louis

Wed 3/12

2:00 p.m.-10:25 p.m.

1 stop7h 25m

C$ 402

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 26/2

6:50 p.m.-11:40 p.m.

1 stop5h 50m

Lambert-St Louis

Sun 1/3

6:45 a.m.-11:51 a.m.

1 stop4h 06m

C$ 436

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 6/2

2:54 p.m.-8:06 p.m.

1 stop6h 12m

Lambert-St Louis

Sat 7/2

7:10 a.m.-1:11 p.m.

1 stop5h 01m

C$ 436

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 2/3

12:35 p.m.-4:40 p.m.

1 stop5h 05m

Lambert-St Louis

Thu 12/3

5:30 a.m.-10:30 a.m.

1 stop4h 00m

C$ 436

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 4/2

12:20 p.m.-7:00 p.m.

1 stop7h 40m

Lambert-St Louis

Fri 6/2

4:30 p.m.-9:15 p.m.

1 stop3h 45m

C$ 436

BuffaloSpringfield

BUF - SGF

BUFSGF

Buffalo

Thu 11/12

6:12 a.m.-3:23 p.m.

2 stops10h 11m

Springfield-Branson

Mon 15/12

4:08 p.m.-11:59 p.m.

1 stop6h 51m

C$ 445

BuffaloSpringfield

BUF - SGF

BUFSGF

Buffalo

Sat 28/2

6:00 a.m.-12:04 p.m.

1 stop7h 04m

Springfield-Branson

Wed 4/3

11:45 a.m.-10:58 p.m.

2 stops10h 13m

C$ 445

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Tue 16/12

1:50 p.m.-5:25 p.m.

1 stop4h 35m

Kansas City

Fri 2/1

7:40 a.m.-1:24 p.m.

1 stop4h 44m

C$ 471

BuffaloKansas City

BUF - MCI

BUFMCI

Buffalo

Mon 15/12

1:16 p.m.-5:00 p.m.

1 stop4h 44m

Kansas City

Sat 3/1

6:30 a.m.-11:21 a.m.

1 stop3h 51m

C$ 471

Flights are sorted by cheapest round-trip flights first.

Deals found on 30/10

Showing 1-10 of 30 results
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Best time to book a flight from Buffalo to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Missouri

What is the cheapest month to book a flight from Buffalo to Missouri?

Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of C$ 156). Flying from Buffalo to Missouri in December is currently the most expensive (average of C$ 387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to MO?

Find hourly flight availability from Buffalo to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 October 2025.

One of the essential ways to save on airfare from Buffalo to Missouri is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 17% on airfare.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated 30 October 2025.
Check out reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Buffalo to Missouri to help guide your decision. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,243 reviews
Check prices

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,243 reviews
Southwest
8.0
Very good
4,243 reviews
Check prices

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,243 reviews
Check prices

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,035 reviews
Southwest
8.0
Very good
4,243 reviews
Check prices

Crew

8.6

Comfort

8.0

Food

7.0

Entertainment

7.5

Boarding

8.1

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Buffalo to Missouri?

    For a flight from Buffalo to Missouri, you will be flying from Buffalo. Buffalo (BUF) is just 13.4 km from the centre of the city.

  • How long is the flight from Buffalo to Missouri?

    Departing from Buffalo to Missouri will take you 4h 35m. Buffalo and Missouri are separated by a distance of 1395 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the cheapest airlines to fly from Buffalo to Missouri one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as C$ 197. Users have also found prices from C$ 236 and C$ 341 on United Airlines and Southwest, respectively.

  • What are the most popular routes from Buffalo to Missouri?

    When deciding which route to take from Buffalo to Missouri consider Buffalo - Lambert-St Louis, Buffalo - Joplin or Buffalo - Kansas City as they are the most popular.

  • Can I find deals for flights from Buffalo to Missouri that include hotel bookings?

    Yes. In addition to deals on Buffalo to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Missouri.

  • Can I find deals for business class flights from Buffalo to Missouri?

    Yes. Cheapflights offers flight deals from Buffalo to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to Missouri (average of C$ 156). Flying from Buffalo to Missouri in December is currently the most expensive (average of C$ 387). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Buffalo to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from Buffalo to Missouri

Discover the top 3 airlines that operate flights from Buffalo to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 30 October 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapestC$ 310AverageC$ 442FlexibilityNo cancel feeOn-time71%
Search American Airlines flights
DeltaCheapestC$ 317AverageC$ 454FlexibilityNo cancel feeOn-timeN/A
Search Delta flights
SouthwestCheapestC$ 358AverageC$ 542FlexibilityNo cancel feeOn-time63%
Search Southwest flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Buffalo to Missouri?

Deals for Buffalo to Missouri flights are sourced from 900+ travel sites when you use Cheapflights. When all flight results come back, Cheapflights lets you sort and filter flights using different criteria to choose better, like price, airport, cabin class, and plenty of other options.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to Missouri?

Cheapflights helps you find that perfect flight to Missouri from Buffalo by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Buffalo to Missouri with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Buffalo to Missouri flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Buffalo to Missouri become cheaper?

Yes, Cheapflights offers price alerts on Buffalo to Missouri flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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