Cheap flights from Detroit Metropolitan Wayne County Airport to San Francisco from C$ 223
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/7. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SFO
26 May — 2 Jun1
Round-trip
1 adult
Economy
Round-trip
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to San Francisco are usually found in January or July, booked 79 days in advance, depart on a Wednesday or Thursday and return on a Monday
Cheap flight deals from Detroit to San Francisco
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Cheapest flights from Detroit to San Francisco
Explore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 April 2026.
Thu 18/612:30 p.m.
DTW
-
SFO
1 stop25h 04m
Frontier
Tue 23/67:17 p.m.
SFO
-
DTW
1 stop9h 05m
Frontier
Deal found 21/4C$ 406
Wed 8/71:22 p.m.
DTW
-
SFO
1 stop14h 00m
Frontier
Mon 13/77:12 p.m.
SFO
-
DTW
1 stop9h 09m
Frontier
Deal found 21/4C$ 407
Mon 4/510:27 p.m.
DTW
-
SFO
1 stop28h 56m
Frontier
Fri 8/510:40 p.m.
SFO
-
DTW
2 stops22h 19m
Frontier
Deal found 21/4C$ 410
Tue 18/87:00 a.m.
DTW
-
SFO
2 stops8h 35m
Southwest
Sat 22/85:00 a.m.
SFO
-
DTW
1 stop8h 50m
Southwest
Deal found 23/4C$ 414
Tue 7/712:37 p.m.
DTW
-
SFO
1 stop24h 38m
Frontier
Mon 13/79:39 p.m.
SFO
-
DTW
1 stop11h 55m
Frontier
Deal found 25/4C$ 415
Tue 18/87:00 a.m.
DTW
-
SFO
2 stops8h 35m
Southwest
Mon 24/811:55 a.m.
SFO
-
DTW
2 stops8h 40m
Southwest
Deal found 23/4C$ 422
Wed 8/78:52 a.m.
DTW
-
SFO
2 stops26h 51m
Frontier
Tue 14/77:11 p.m.
SFO
-
DTW
1 stop9h 10m
Frontier
Deal found 25/4C$ 430
Thu 21/51:20 p.m.
DTW
-
SFO
1 stop21h 41m
Frontier
Tue 26/57:15 p.m.
SFO
-
DTW
1 stop9h 07m
Frontier
Deal found 24/4C$ 440
Wed 11/114:46 p.m.
DTW
-
SFO
1 stop8h 23m
Alaska Airlines
Mon 16/119:15 a.m.
SFO
-
DTW
1 stop27h 33m
Alaska Airlines
Deal found 21/4C$ 450
Mon 6/78:01 p.m.
DTW
-
SFO
1 stop23h 05m
Frontier
Sun 12/712:33 p.m.
SFO
-
DTW
1 stop8h 26m
Frontier
Deal found 25/4C$ 456
Best flights from Detroit to San Francisco
Discover carefully curated flight deals from Detroit to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 26 April 2026.
Tue 14/78:25 p.m.
DTW
-
SFO
Nonstop4h 59m
Delta
Mon 20/710:55 p.m.
SFO
-
DTW
Nonstop4h 32m
Delta
Deal found 25/4C$ 477
Thu 17/97:00 a.m.
DTW
-
SFO
1 stop10h 27m
Alaska Airlines
Thu 24/97:00 a.m.
SFO
-
DTW
1 stop19h 23m
Alaska Airlines
Deal found 23/4C$ 477
Tue 2/65:40 p.m.
DTW
-
SFO
2 stops8h 35m
Southwest
Sat 6/66:10 a.m.
SFO
-
DTW
2 stops9h 30m
Southwest
Deal found 21/4C$ 526
Wed 27/55:29 p.m.
DTW
-
SFO
Nonstop5h 08m
United Airlines
Sun 31/59:30 p.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 21/4C$ 629
Wed 8/78:25 p.m.
DTW
-
SFO
Nonstop4h 59m
Delta
Mon 13/711:56 p.m.
SFO
-
DTW
Nonstop4h 31m
Delta
Deal found 25/4C$ 477
Wed 27/58:25 p.m.
DTW
-
SFO
Nonstop4h 56m
Delta
Mon 1/611:59 p.m.
SFO
-
DTW
Nonstop4h 34m
Delta
Deal found 25/4C$ 477
Thu 22/107:00 a.m.
DTW
-
SFO
1 stop9h 48m
Alaska Airlines
Tue 27/108:00 a.m.
SFO
-
DTW
2 stops18h 05m
Alaska Airlines
Deal found 21/4C$ 542
Wed 27/51:40 p.m.
DTW
-
SFO
2 stops11h 25m
Southwest
Sun 31/51:10 p.m.
SFO
-
DTW
1 stop6h 55m
Southwest
Deal found 21/4C$ 619
Wed 24/61:25 p.m.
DTW
-
SFO
2 stops9h 30m
Southwest
Wed 1/710:25 a.m.
SFO
-
DTW
2 stops10h 40m
Southwest
Deal found 25/4C$ 627
Wed 8/78:20 p.m.
DTW
-
SFO
1 stop6h 32m
Delta
Sun 12/710:30 p.m.
SFO
-
DTW
Nonstop4h 32m
Delta
Deal found 21/4C$ 593
Direct flights from Detroit to San Francisco
Explore direct flight options from Detroit to San Francisco based on user searches, and compare prices and availability for your desired travel dates. Data last updated 26 April 2026.
Wed 22/76:55 p.m.
DTW
-
SFO
Nonstop5h 00m
Delta
Wed 29/711:32 p.m.
SFO
-
DTW
Nonstop4h 31m
Delta
Deal found 21/4C$ 477
Sat 23/55:29 p.m.
DTW
-
SFO
Nonstop5h 11m
United Airlines
Wed 27/58:35 a.m.
SFO
-
DTW
Nonstop4h 48m
United Airlines
Deal found 23/4C$ 512
Thu 25/66:34 a.m.
DTW
-
SFO
Nonstop5h 06m
United Airlines
Sat 4/78:55 a.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 22/4C$ 514
Fri 5/66:34 a.m.
DTW
-
SFO
Nonstop5h 06m
United Airlines
Sun 7/69:30 p.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 23/4C$ 526
Thu 21/56:34 a.m.
DTW
-
SFO
Nonstop5h 06m
United Airlines
Sun 24/59:30 p.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 21/4C$ 532
Mon 13/78:25 p.m.
DTW
-
SFO
Nonstop4h 57m
Delta
Sun 19/710:30 p.m.
SFO
-
DTW
Nonstop4h 32m
Delta
Deal found 21/4C$ 552
Sat 23/55:29 p.m.
DTW
-
SFO
Nonstop5h 11m
United Airlines
Tue 26/58:35 a.m.
SFO
-
DTW
Nonstop4h 48m
United Airlines
Deal found 23/4C$ 567
Thu 7/58:35 a.m.
DTW
-
SFO
Nonstop5h 23m
United Airlines
Thu 28/59:30 p.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 22/4C$ 568
Wed 20/58:35 a.m.
DTW
-
SFO
Nonstop5h 23m
United Airlines
Sun 31/59:30 p.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 22/4C$ 578
Tue 12/58:25 p.m.
DTW
-
SFO
Nonstop4h 56m
Delta
Tue 19/511:59 p.m.
SFO
-
DTW
Nonstop4h 34m
Delta
Deal found 24/4C$ 579
Fri 26/66:34 a.m.
DTW
-
SFO
Nonstop5h 06m
United Airlines
Tue 7/78:35 a.m.
SFO
-
DTW
Nonstop4h 52m
United Airlines
Deal found 22/4C$ 581
Tue 9/65:29 p.m.
DTW
-
SFO
Nonstop5h 11m
United Airlines
Sat 13/69:30 p.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 23/4C$ 586
Last-minute flights from Detroit to San Francisco
Discover last-minute flight deals from Detroit to San Francisco. Data last updated 26 April 2026 and is based on user searches.
Mon 4/510:27 p.m.
DTW
-
SFO
1 stop28h 56m
Frontier
Fri 8/510:40 p.m.
SFO
-
DTW
2 stops22h 19m
Frontier
Deal found 21/4C$ 410
Tue 12/51:40 p.m.
DTW
-
SFO
2 stops11h 25m
Southwest
Tue 19/510:30 a.m.
SFO
-
DTW
2 stops9h 35m
Southwest
Deal found 22/4C$ 519
Tue 19/56:35 a.m.
DTW
-
SFO
2 stops10h 55m
Southwest
Tue 26/510:40 p.m.
SFO
-
DTW
1 stop11h 00m
Southwest
Deal found 21/4C$ 534
Wed 20/56:00 a.m.
DTW
-
SFO
1 stop8h 24m
United Airlines
Sun 24/59:30 p.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 24/4C$ 536
Thu 21/51:20 p.m.
DTW
-
SFO
1 stop21h 41m
Frontier
Tue 26/57:15 p.m.
SFO
-
DTW
1 stop9h 07m
Frontier
Deal found 24/4C$ 440
Thu 21/56:34 a.m.
DTW
-
SFO
Nonstop5h 06m
United Airlines
Sun 24/59:30 p.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 21/4C$ 532
Fri 22/56:05 p.m.
DTW
-
SFO
2 stops25h 36m
Frontier
Fri 29/512:52 p.m.
SFO
-
DTW
1 stop8h 07m
Frontier
Deal found 22/4C$ 430
Fri 22/56:25 a.m.
DTW
-
SFO
2 stops9h 10m
Southwest
Wed 27/55:25 a.m.
SFO
-
DTW
1 stop7h 10m
Southwest
Deal found 22/4C$ 538
Sat 23/55:29 p.m.
DTW
-
SFO
Nonstop5h 11m
United Airlines
Wed 27/58:35 a.m.
SFO
-
DTW
Nonstop4h 48m
United Airlines
Deal found 23/4C$ 512
Sat 23/55:29 p.m.
DTW
-
SFO
Nonstop5h 11m
United Airlines
Tue 26/511:30 p.m.
SFO
-
DTW
1 stop7h 27m
United Airlines
Deal found 23/4C$ 526
Wed 27/55:29 p.m.
DTW
-
SFO
Nonstop5h 08m
United Airlines
Sun 31/59:30 p.m.
SFO
-
DTW
Nonstop4h 50m
United Airlines
Deal found 21/4C$ 477
Fri 29/56:34 a.m.
DTW
-
SFO
Nonstop5h 06m
United Airlines
Mon 1/610:38 p.m.
SFO
-
DTW
1 stop8h 19m
United Airlines
Deal found 21/4C$ 491
One-way flights from Detroit to San Francisco
Search for one-way flight options from Detroit to San Francisco. Find affordable one-way fares based on user searches. Data last updated 26 April 2026.
Wed 8/712:35 p.m.
DTW
-
SFO
1 stop24h 54m
Frontier
Deal found 21/4C$ 223
Tue 20/107:00 a.m.
DTW
-
SFO
1 stop8h 07m
Alaska Airlines
Deal found 21/4C$ 225
Tue 7/78:01 p.m.
DTW
-
SFO
2 stops17h 24m
Frontier
Deal found 23/4C$ 230
Mon 8/67:55 a.m.
DTW
-
SFO
2 stops18h 09m
Frontier
Deal found 24/4C$ 231
Sun 7/67:53 p.m.
DTW
-
SFO
2 stops15h 56m
Frontier
Deal found 22/4C$ 239
Thu 25/68:30 p.m.
DTW
-
SFO
1 stop6h 40m
Southwest
Deal found 21/4C$ 253
Sat 9/57:55 a.m.
DTW
-
SFO
2 stops13h 07m
Frontier
Deal found 21/4C$ 258
Wed 30/91:45 p.m.
DTW
-
SFO
2 stops8h 20m
Southwest
Deal found 23/4C$ 260
Find flight deals from Detroit to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 26 April 2026.
Customize your flight search to find flights from Detroit to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 26 April 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Cheapest round-trip
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Tue 14/7
8:25 p.m.-10:24 p.m.
Nonstop4h 59m
San Francisco
Mon 20/7
10:55 p.m.-6:27 a.m.
Nonstop4h 32m
C$ 477
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Thu 17/9
7:00 a.m.-2:27 p.m.
1 stop10h 27m
San Francisco
Thu 24/9
7:00 a.m.-5:23 a.m.
1 stop19h 23m
C$ 477
Quickest round-trip
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Wed 8/7
8:25 p.m.-10:24 p.m.
Nonstop4h 59m
San Francisco
Mon 13/7
11:56 p.m.-7:27 a.m.
Nonstop4h 31m
C$ 477
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Wed 27/5
8:25 p.m.-10:21 p.m.
Nonstop4h 56m
San Francisco
Mon 1/6
11:59 p.m.-7:33 a.m.
Nonstop4h 34m
C$ 477
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Tue 2/6
5:40 p.m.-11:15 p.m.
2 stops8h 35m
San Francisco
Sat 6/6
6:10 a.m.-6:40 p.m.
2 stops9h 30m
C$ 526
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Thu 22/10
7:00 a.m.-1:48 p.m.
1 stop9h 48m
San Francisco
Tue 27/10
8:00 a.m.-5:05 a.m.
2 stops18h 05m
C$ 542
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Wed 8/7
8:20 p.m.-11:52 p.m.
1 stop6h 32m
San Francisco
Sun 12/7
10:30 p.m.-6:02 a.m.
Nonstop4h 32m
C$ 593
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Wed 27/5
1:40 p.m.-10:05 p.m.
2 stops11h 25m
San Francisco
Sun 31/5
1:10 p.m.-11:05 p.m.
1 stop6h 55m
C$ 619
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Wed 24/6
1:25 p.m.-7:55 p.m.
2 stops9h 30m
San Francisco
Wed 1/7
10:25 a.m.-12:05 a.m.
2 stops10h 40m
C$ 627
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Wed 27/5
5:29 p.m.-7:37 p.m.
Nonstop5h 08m
San Francisco
Sun 31/5
9:30 p.m.-5:20 a.m.
Nonstop4h 50m
C$ 629
Flights are sorted by cheapest round-trip flights first.
Deals found on 21/4
Showing 1-10 of 20 resultsSorted by cheapest first
1
2
Best time to book a flight from Detroit to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Detroit with our price prediction graph.
DTW-SFO
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to San Francisco
Prices
Airlines
More
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?
The best time to book flights from Detroit Metropolitan Wayne County Airport to San Francisco is 78 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Francisco (average of C$ 532). Flying from Detroit Metropolitan Wayne County Airport to San Francisco in March is currently the most expensive (average of C$ 702). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to SFO?
Find hourly flight availability from Detroit to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 26 April 2026.
A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to San Francisco in the morning. If you’re flexible enough to do this you can expect to save up to 40% on your trip compared to booking a flight in the evening.
How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to San Francisco?
Weekly flight availability from Detroit Metropolitan Wayne County Airport to San Francisco
Explore weekly flight availability from Detroit to San Francisco. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 26 April 2026.
The most flights from DTW to SFO are scheduled on a Monday (11 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (7 on average).
What’s the top layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?
Share of one-stop round-trip flights from Detroit Metropolitan Wayne County Airport to San Francisco chosen by Cheapflights users in the past 12 months, using the same layover each way.
Chicago (ORD) – chosen by Cheapflights users on 56% of one-stop itineraries from Detroit Metropolitan Wayne County Airport to San Francisco on Cheapflights.
What’s the cheapest layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?
Average round-trip fare for 1-stop flights from Detroit Metropolitan Wayne County Airport to San Francisco, chosen by Cheapflights users in the past 12 months, with the same layover each way.
Minneapolis (MSP) is the most affordable 1-stop option, with an average round-trip price of C$ 394.
What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to San Francisco?
Shortest average travel time for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to San Francisco, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Minneapolis (MSP) have the shortest average one-way travel time for 1-stop routes: 6h 44m.
Which airport typically offers the quickest layover for flights from Detroit Metropolitan Wayne County Airport to San Francisco?
Average layover duration for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to San Francisco, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Charlotte (CLT) offer the fastest connection on this route, with an average layover time of 0h 49m.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated 26 April 2026.
Check out reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Detroit Metropolitan Wayne County Airport to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
I had to try and sleep on the floor of the Austin airport. I spent 12 hours there. The airline policies were so poor, that a near violent argument broke out between the people in front of me and the flight attendants - making for a super stressful situation at 30,000 feet. Garbage airline choice by Kayak Garbage idea to book a flight with a layover. Next time I will pay for a quality booking myself, and somehow force the company to reimburse it.
Related info for your journey
Find useful and relevant information for your journey from Detroit to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Detroit to San Francisco?
To fly from Detroit to San Francisco, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to San Francisco (SFO). Nonstop flights to San Francisco from Detroit Metropolitan Wayne County take 5h 00m on average. When it comes time to book airfare, you have a few options: there are 10 outbound flights from Detroit Metropolitan Wayne County to San Francisco offered by 5 different airlines.
How long is the flight from Detroit Metropolitan Wayne County Airport to San Francisco?
There are many flights that can get you from Detroit Metropolitan Wayne County Airport to San Francisco in 4h 59m. Fly via Delta, Alaska Airlines, or Southwest to get the fastest option. Detroit Metropolitan Wayne County Airport and San Francisco are separated by a distance of 3335 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco round-trip?
Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to San Francisco round-trip from C$ 218. Other airlines that can offer you cheap pricing are Delta, from C$ 289, and United Airlines, from C$ 382. These flights start at 63% lower than the current average price 3 months from now.
What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to San Francisco?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to San Francisco on time: Asiana Airlines (77%), Air New Zealand (77%), United Airlines (77%).
What are the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco?
Looking at all options, your cheapest flight can be booked for C$ 380. While the most popular route (Detroit Metropolitan Wayne County - San Francisco) can be booked for C$ 477 on average, our data indicates C$ 978 when flying from Detroit Metropolitan Wayne County Airport to San Francisco.
Can I find deals for business class flights from Detroit to San Francisco?
Yes. Cheapflights offers flight deals from Detroit to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Francisco (average of C$ 532). Flying from Detroit Metropolitan Wayne County Airport to San Francisco in March is currently the most expensive (average of C$ 702). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 26 April 2026.
Top 5 airlines flying from Detroit to San Francisco
Discover the top 5 airlines that operate flights from Detroit to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 26 April 2026.
Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Detroit to San Francisco?
900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to San Francisco from Detroit today with Cheapflights!
Why should you use Cheapflights to find cheap flight tickets from Detroit to San Francisco?
It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Detroit to San Francisco.
Can Cheapflights find flights from Detroit to San Francisco with no change fees?
Certainly. Search results for flights to San Francisco from Detroit shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Detroit to San Francisco become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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