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Cheap flights from Santa Cruz de la Sierra to Panama City from C$ 676

VVI — PTY
5 Dec — 12 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santa Cruz de la Sierra to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Santa Cruz de la Sierra to Panama City

Mon 30/111:10 a.m. -
Nonstop4h 54m
Wed 13/19:45 p.m. -
Nonstop4h 59m
Deal found 5/11C$ 1,093
Mon 2/113:45 a.m. -
1 stop14h 30m
Tue 10/1110:05 a.m. -
1 stop15h 35m
Deal found 2/11C$ 1,125
Thu 19/1111:41 a.m. -
Nonstop4h 58m
Mon 23/114:40 p.m. -
Nonstop4h 58m
Deal found 2/11C$ 1,205
Fri 20/111:08 a.m. -
Nonstop4h 56m
Fri 27/114:40 p.m. -
Nonstop4h 58m
Deal found 5/11C$ 1,206
Thu 24/121:10 a.m. -
Nonstop4h 54m
Fri 1/14:40 p.m. -
Nonstop5h 06m
Deal found 2/11C$ 1,216
Thu 10/1211:34 a.m. -
Nonstop5h 05m
Thu 17/124:40 p.m. -
Nonstop5h 08m
Deal found 1/11C$ 1,254
Thu 3/121:10 a.m. -
Nonstop4h 54m
Fri 11/124:40 p.m. -
Nonstop5h 08m
Deal found 4/11C$ 1,274
Sun 8/111:08 a.m. -
Nonstop4h 56m
Mon 16/114:40 p.m. -
Nonstop4h 58m
Deal found 1/11C$ 1,278
Tue 10/111:08 a.m. -
Nonstop4h 56m
Fri 20/119:45 p.m. -
Nonstop4h 52m
Deal found 4/11C$ 1,279
Fri 20/111:08 a.m. -
Nonstop4h 56m
Fri 4/124:40 p.m. -
Nonstop5h 08m
Deal found 2/11C$ 1,308
Thu 3/121:10 a.m. -
Nonstop4h 54m
Fri 8/14:40 p.m. -
Nonstop5h 06m
Deal found 1/11C$ 1,331

Find flight deals from Santa Cruz de la Sierra to Panama City

Round-trip from

C$ 1,093

One-way from

C$ 676

Popular in

February

Cheapest in

April

Average price

C$ 1,095
Copa Airlines
  • Copa Airlines
  • 18/12-27/12
  • Nonstop
  • 10h 02m total
  • Santa Cruz de la Sierra to Panama City
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Avianca
  • Avianca
  • 24/11-31/12
  • 1 total stop
  • 14h 30m total
  • Santa Cruz de la Sierra to Panama City
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Highest demand for flights based on searches. 5% potential increase in price (C$ 92 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease (C$ 32 potential savings vs. average RT price).
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Average for round-trip flights in November 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Mon 23/11

3:45 a.m.-3:15 p.m.

1 stop12h 30m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 714

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Fri 20/11

3:45 a.m.-1:20 a.m.

1 stop22h 35m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 714

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Thu 19/11

3:45 a.m.-5:15 p.m.

1 stop14h 30m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 813

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Wed 18/11

3:45 a.m.-5:15 p.m.

1 stop14h 30m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 924
Quickest round-trip

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/1

11:53 a.m.-3:47 p.m.

Nonstop4h 54m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 927

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Tue 12/1

11:53 a.m.-3:47 p.m.

Nonstop4h 54m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 929

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Mon 30/11

1:10 a.m.-5:04 a.m.

Nonstop4h 54m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 929

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Fri 18/12

1:10 a.m.-5:04 a.m.

Nonstop4h 54m

Panama City Tocumen Intl

Sun 27/12

4:40 p.m.-10:48 p.m.

Nonstop5h 08m

C$ 1,093

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Thu 14/1

1:14 a.m.-5:04 a.m.

Nonstop4h 50m

Panama City Tocumen Intl

Fri 22/1

9:45 p.m.-3:44 a.m.

Nonstop4h 59m

C$ 1,093

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Fri 12/2

1:18 a.m.-5:04 a.m.

Nonstop4h 46m

Panama City Tocumen Intl

Fri 19/2

4:40 p.m.-10:42 p.m.

Nonstop5h 02m

C$ 1,093

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/11

Showing 1-10 of 15 resultsSorted by cheapest first
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Best time to book a flight from Santa Cruz de la Sierra to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Panama City

How far ahead should I book a flight from Santa Cruz de la Sierra to Panama City?

The price you pay for your flight from Santa Cruz de la Sierra to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 39 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Panama City?

Currently, April is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Panama City (average of C$ 867). Flying from Santa Cruz de la Sierra to Panama City in February is currently the most expensive (average of C$ 1,308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from VVI to PTY?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santa Cruz de la Sierra to Panama City as you normally would.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to Panama City?

Airfare is typical for this route at the moment.

Santa Cruz de la Sierra to Panama City flights typically cost between C$ 1,093 and C$ 1,112 in February.
The cheapest round-trip price found within the last 5 days was C$ 1,093 on Copa Airlines (4 Feb-14 Feb).

Related info for your journey

  • How popular is this Santa Cruz de la Sierra to Panama City flight route?

    Flights from Santa Cruz de la Sierra Viru Viru Intl to Panama City Tocumen Intl have been viewed 6 times in the past calendar month.

  • How long is the flight from Santa Cruz de la Sierra to Panama City?

    Departing from Santa Cruz de la Sierra to Panama City will take you 4h 54m. There are 3463 km between Santa Cruz de la Sierra and Panama City. All flights are typically direct.

  • Can I find deals for flights from Santa Cruz de la Sierra to Panama City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Panama City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Panama City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Panama City?

    Currently, April is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Panama City (average of C$ 867). Flying from Santa Cruz de la Sierra to Panama City in February is currently the most expensive (average of C$ 1,308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Users can book flights with no change fees policies with our dedicated filters. Book flights from Santa Cruz de la Sierra to Panama City flexibly with Cheapflights today.

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Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Panama City from Santa Cruz de la Sierra today and book when prices fit your budget.

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