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Cheap flights from Santa Cruz de la Sierra to Panama City from C$ 698

VVI — PTY
20 Oct — 27 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santa Cruz de la Sierra to Panama City

Enter your travel dates to find the best prices.

Cheapest flights from Santa Cruz de la Sierra to Panama City

Wed 21/101:12 a.m. -
Nonstop4h 52m
Mon 26/104:40 p.m. -
Nonstop5h 04m
Deal found 17/9C$ 1,093
Wed 14/101:12 a.m. -
Nonstop4h 52m
Sat 24/104:40 p.m. -
Nonstop5h 04m
Deal found 17/9C$ 1,105
Mon 12/101:12 a.m. -
Nonstop4h 52m
Tue 20/104:40 p.m. -
Nonstop5h 04m
Deal found 18/9C$ 1,106
Sun 1/111:08 a.m. -
Nonstop4h 56m
Mon 16/114:40 p.m. -
Nonstop4h 58m
Deal found 17/9C$ 1,107
Wed 16/93:35 a.m. -
1 stop6h 40m
Wed 23/93:10 p.m. -
1 stop10h 20m
Deal found 15/9C$ 1,173
Fri 30/103:45 a.m. -
1 stop14h 30m
Sat 14/114:10 p.m. -
1 stop9h 30m
Deal found 17/9C$ 1,184
Sat 31/103:45 a.m. -
1 stop12h 30m
Sat 14/1110:05 a.m. -
1 stop15h 35m
Deal found 19/9C$ 1,187
Tue 29/91:12 a.m. -
Nonstop4h 52m
Sat 10/104:40 p.m. -
Nonstop5h 04m
Deal found 16/9C$ 1,216
Wed 30/1211:42 a.m. -
Nonstop5h 05m
Wed 6/19:45 p.m. -
Nonstop4h 59m
Deal found 15/9C$ 1,222
Tue 27/103:45 a.m. -
1 stop14h 30m
Sun 15/112:30 a.m. -
1 stop23h 10m
Deal found 15/9C$ 1,249

Find flight deals from Santa Cruz de la Sierra to Panama City

Round-trip from

C$ 1,093

One-way from

C$ 698

Popular in

July

Cheapest in

November

Average price

C$ 1,029
Copa Airlines
  • Copa Airlines
  • 21/10-26/10
  • Nonstop
  • 9h 56m total
  • Santa Cruz de la Sierra to Panama City
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Avianca
  • Avianca
  • 26/2-31/12
  • 1 total stop
  • 12h 30m total
  • Santa Cruz de la Sierra to Panama City
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Highest demand for flights based on searches. 8% potential increase in price (C$ 122 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 15 potential savings vs. average RT price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Fri 26/2

3:45 a.m.-3:15 p.m.

1 stop12h 30m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 698

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Tue 1/12

11:34 a.m.-3:39 p.m.

Nonstop5h 05m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 931

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Sat 17/10

1:12 a.m.-5:04 a.m.

Nonstop4h 52m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 941

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Fri 20/11

1:08 a.m.-5:04 a.m.

Nonstop4h 56m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 941
Quickest round-trip

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Tue 26/1

1:14 a.m.-5:04 a.m.

Nonstop4h 50m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 941

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Tue 1/12

11:34 a.m.-3:39 p.m.

Nonstop5h 05m

Panama City Tocumen Intl

Wed 13/1

4:40 p.m.-10:46 p.m.

Nonstop5h 06m

C$ 1,093

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Tue 27/10

11:55 a.m.-3:47 p.m.

Nonstop4h 52m

Panama City Tocumen Intl

Mon 2/11

4:40 p.m.-10:38 p.m.

Nonstop4h 58m

C$ 1,093

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Thu 22/10

11:47 a.m.-3:39 p.m.

Nonstop4h 52m

Panama City Tocumen Intl

Mon 26/10

4:40 p.m.-10:44 p.m.

Nonstop5h 04m

C$ 1,098

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Wed 14/10

1:12 a.m.-5:04 a.m.

Nonstop4h 52m

Panama City Tocumen Intl

Sat 24/10

4:40 p.m.-10:44 p.m.

Nonstop5h 04m

C$ 1,105

Santa Cruz de la SierraPanama City

VVI Santa Cruz de la Sierra Viru Viru Intl - PTY Panama City Tocumen Intl

VVIPTY

Santa Cruz de la Sierra Viru Viru Intl

Sat 17/10

1:12 a.m.-5:04 a.m.

Nonstop4h 52m

Panama City Tocumen Intl

Sun 25/10

9:45 p.m.-3:40 a.m.

Nonstop4h 55m

C$ 1,107

Flights are sorted by cheapest round-trip flights first.

Deals found on 16/9

Showing 1-10 of 15 resultsSorted by cheapest first
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Best time to book a flight from Santa Cruz de la Sierra to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Panama City

How far ahead should I book a flight from Santa Cruz de la Sierra to Panama City?

The price you pay for your flight from Santa Cruz de la Sierra to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 42 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Panama City?

Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Panama City (average of C$ 831). Flying from Santa Cruz de la Sierra to Panama City in July is currently the most expensive (average of C$ 1,102). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from VVI to PTY?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santa Cruz de la Sierra to Panama City as you normally would.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to Panama City?

Airfare is above average for this route at the moment.

Santa Cruz de la Sierra to Panama City flights typically cost between C$ 849 and C$ 1,081 in October.
The cheapest round-trip price found within the last 5 days was C$ 1,093 on Copa Airlines (21 Oct-26 Oct).

Related info for your journey

  • How popular is this Santa Cruz de la Sierra to Panama City flight route?

    Flights from Santa Cruz de la Sierra Viru Viru Intl to Panama City Tocumen Intl have been viewed 6 times in the past calendar month.

  • How long is the flight from Santa Cruz de la Sierra to Panama City?

    Departing from Santa Cruz de la Sierra to Panama City will take you 4h 52m. There are 3463 km between Santa Cruz de la Sierra and Panama City. All flights are typically direct.

  • Can I find deals for flights from Santa Cruz de la Sierra to Panama City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Panama City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Panama City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Panama City?

    Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Panama City (average of C$ 831). Flying from Santa Cruz de la Sierra to Panama City in July is currently the most expensive (average of C$ 1,102). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Users can book flights with no change fees policies with our dedicated filters. Book flights from Santa Cruz de la Sierra to Panama City flexibly with Cheapflights today.

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Yes, Cheapflights has a feature called Price Alert, which notifies users when flight prices change. Track prices for your flight to Panama City from Santa Cruz de la Sierra today and book when prices fit your budget.

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