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Cheap flights from Santiago to Cusco from C$ 150

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/3. Fares are subject to change and may not be available on all flights or dates of travel.
SCL — CUZ
27 Nov — 4 Dec1
1 adult
1 adult, Economy, 0 bags

Find flight deals from Santiago to Cuzco

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Cuzco
Explore the most affordable flight options available from Santiago to Cuzco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 October 2025.

Sun 30/111:35 a.m.SCL - CUZ
2 stops16h 30mSky Airline
Thu 4/127:05 a.m.CUZ - SCL
1 stop13h 10mSky Airline
Deal found 28/10C$ 295
Tue 11/111:35 a.m.SCL - CUZ
2 stops20h 10mSky Airline
Wed 19/117:10 a.m.CUZ - SCL
1 stop13h 05mSky Airline
Deal found 27/10C$ 297
Fri 7/119:05 p.m.SCL - CUZ
1 stop11h 25mSky Airline
Wed 12/118:30 p.m.CUZ - SCL
2 stops13h 45mSky Airline
Deal found 26/10C$ 334
Wed 19/111:30 a.m.SCL - CUZ
2 stops20h 50mSky Airline
Wed 3/126:30 p.m.CUZ - SCL
2 stops15h 45mSky Airline
Deal found 28/10C$ 341
Thu 11/125:59 a.m.SCL - CUZ
1 stop18h 27mJetSMART
Thu 18/127:12 a.m.CUZ - SCL
1 stop20h 02mJetSMART
Deal found 27/10C$ 351
Wed 3/121:30 a.m.SCL - CUZ
2 stops16h 35mSky Airline
Mon 8/128:30 p.m.CUZ - SCL
1 stop16h 10mSky Airline
Deal found 28/10C$ 354
Fri 7/115:50 a.m.SCL - CUZ
1 stop13h 55mSky Airline
Fri 14/118:30 p.m.CUZ - SCL
1 stop16h 10mSky Airline
Deal found 27/10C$ 355
Wed 3/121:30 a.m.SCL - CUZ
2 stops20h 15mSky Airline
Fri 5/128:30 p.m.CUZ - SCL
2 stops13h 45mSky Airline
Deal found 27/10C$ 372
Wed 10/1211:05 p.m.SCL - CUZ
1 stop9h 20mSky Airline
Mon 15/128:30 p.m.CUZ - SCL
2 stops13h 45mSky Airline
Deal found 28/10C$ 378
Sat 8/119:05 p.m.SCL - CUZ
1 stop12h 15mSky Airline
Fri 14/118:30 p.m.CUZ - SCL
2 stops13h 45mSky Airline
Deal found 27/10C$ 379
Thu 6/111:35 a.m.SCL - CUZ
2 stops18h 10mSky Airline
Thu 13/116:30 p.m.CUZ - SCL
1 stop9h 20mSky Airline
Deal found 27/10C$ 380

Cheap flight deals from Santiago to Cuzco

Discover tips and strategies to find the most affordable flight options for your journey from Santiago (SCL) to Cuzco (CUZ). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 October 2025.

Round-trip from

C$ 288

One-way from

C$ 150

Popular in

January

Cheapest in

March

Average price

C$ 385
JetSMART
  • JetSMART
  • 14/3-17/3
  • 2 total stops
  • 23h 09m total
  • Santiago to Cusco
Search Deals
JetSMART
  • JetSMART
  • 28/3
  • 1 total stop
  • 7h 07m total
  • Santiago to Cusco
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (C$ 18 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease (C$ 5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santiago to Cuzco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 28 October 2025.
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Santiago

Fly to

Cuzco

Route

Depart

Return

Price

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 19/3

12:30 p.m.-9:05 p.m.

1 stop10h 35m

Cusco Velazco Astete

Sun 22/3

12:10 p.m.-2:40 p.m.

1 stop24h 30m

C$ 292

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 12/3

1:35 a.m.-4:05 p.m.

2 stops16h 30m

Cusco Velazco Astete

Sun 22/3

12:10 p.m.-10:15 p.m.

1 stop8h 05m

C$ 294

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 13/3

1:35 a.m.-5:55 p.m.

2 stops18h 20m

Cusco Velazco Astete

Tue 17/3

12:10 p.m.-10:15 p.m.

1 stop8h 05m

C$ 294

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 23/2

12:35 p.m.-9:05 p.m.

1 stop10h 30m

Cusco Velazco Astete

Wed 4/3

9:45 p.m.-2:40 p.m.

1 stop14h 55m

C$ 295

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Mon 1/12

9:10 p.m.-6:25 a.m.

1 stop11h 15m

Cusco Velazco Astete

Thu 4/12

8:30 p.m.-2:40 p.m.

1 stop16h 10m

C$ 295

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Wed 12/11

9:05 p.m.-6:10 a.m.

1 stop11h 05m

Cusco Velazco Astete

Wed 19/11

7:10 a.m.-10:15 p.m.

1 stop13h 05m

C$ 297

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Fri 7/11

9:05 p.m.-6:30 a.m.

1 stop11h 25m

Cusco Velazco Astete

Wed 12/11

8:30 p.m.-12:15 p.m.

2 stops13h 45m

C$ 334

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sun 8/3

1:35 a.m.-5:55 p.m.

2 stops18h 20m

Cusco Velazco Astete

Sun 15/3

7:05 a.m.-10:15 p.m.

1 stop13h 10m

C$ 340

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Sat 28/3

11:24 a.m.-4:31 p.m.

1 stop7h 07m

C$ 150

SantiagoCusco

SCL - CUZ

SCLCUZ

Santiago Arturo Merino Benitez

Thu 13/11

12:30 p.m.-7:45 p.m.

1 stop9h 15m

C$ 158

Flights are sorted by cheapest round-trip flights first.

Deals found on 27/10

Showing 1-10 of 13 results
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Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

Use this chart to determine the optimal time to book a round-trip flight from Santiago to Cuzco. Price data was last updated on 24 October 2025.

The best time to book flights from Santiago to Cusco is 81 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of C$ 246). Flying from Santiago to Cusco in September is currently the most expensive (average of C$ 316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

Find hourly flight availability from Santiago to Cuzco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 28 October 2025.

A simple way to save on the total cost of your ticket is to fly from Santiago to Cusco in the evening. If you’re flexible enough to do this you can expect to save up to 35% on your trip compared to booking a flight in the morning.

How much does it cost to fly round-trip from Santiago to Cusco?

Reviews of airlines servicing Cuzco

Get insights into the airlines that provide service to Cuzco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Cuzco. Reviews last updated 28 October 2025.
Get a feel of what it's like to fly with LATAM Airlines from Santiago to Cusco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
LATAM Airlines
7.5
Good
1,871 reviews
Check prices

Overall

7.5

Food

6.7

Boarding

7.5

Entertainment

7.0

Comfort

7.3

Crew

8.0

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!
LATAM Airlines
7.5
Good
1,871 reviews
LATAM Airlines
7.5
Good
1,871 reviews
Check prices

Overall

7.5

Food

6.7

Boarding

7.5

Entertainment

7.0

Comfort

7.3

Crew

8.0

Reviews

1 / 20
8.0
Excellent

LUIS JOSE,Oct 2025

LIM - AEP

Smiles because se upgraded to premiums economy. That was similar to LAN economy years ahí!

Related info for your journey

Find useful and relevant information for your journey from Santiago to Cuzco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santiago to Cusco?

    Sky Airline can get you from Santiago to Cusco in just under 10h 35m. Your travel time can differ by up to . The distance from Santiago to Cusco is about 2210 km.

  • What is the cheapest airline to fly from Santiago to Cusco round-trip?

    Currently priced at C$ 314, LATAM Airlines will fly you from Santiago to Cusco and back. In addition to LATAM Airlines, many other airlines offer competitively priced options for your trip. LATAM Airlines is currently priced 19% below the average price you’ll pay for this route.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of C$ 246). Flying from Santiago to Cusco in September is currently the most expensive (average of C$ 316). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Urubamba

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Alternative routes for Santiago to Cuzco

See prices for flight routes from nearby airports that may be better suited for you.
Santiago to Lima flights

Top airline flying from Santiago to Cuzco

Discover the top airline that operate flights from Santiago to Cuzco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 28 October 2025.
AirlineCheapestAverageFlexibilityOn-time
LATAM AirlinesCheapestC$ 314AverageC$ 432FlexibilityNo cancel feeOn-time81%
Search LATAM Airlines flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Santiago to Cuzco?

Cheapflights helps you search for flights from Santiago to Cuzco via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Santiago to Cuzco?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Santiago to Cuzco.

Can Cheapflights find flights from Santiago to Cuzco with no change fees?

Yes, we can. To see specific flights from Santiago to Cuzco with no change fees, users can toggle flexible booking options after using the search form above to find flights.

Can Cheapflights notify me if prices for flights from Santiago to Cuzco become cheaper?

Yes! Start tracking prices for Santiago to Cuzco flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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