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Cheap flights from Santiago to Cusco from C$ 237

SCL — CUZ
25 Nov — 2 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Cuzco

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Cuzco

Fri 13/118:35 p.m. -
1 stop16h 55m
Fri 20/113:10 p.m. -
1 stop12h 15m
Deal found 23/10C$ 476
Wed 18/117:00 a.m. -
1 stop16h 00m
Mon 23/1112:10 p.m. -
1 stop15h 15m
Deal found 21/10C$ 479
Tue 1/128:35 p.m. -
1 stop16h 55m
Sun 6/127:55 p.m. -
1 stop7h 30m
Deal found 21/10C$ 487
Sun 15/118:35 p.m. -
1 stop11h 40m
Thu 19/116:55 a.m. -
1 stop13h 40m
Deal found 24/10C$ 492
Wed 18/116:07 a.m. -
1 stop16h 38m
Mon 23/1110:55 a.m. -
1 stop16h 05m
Deal found 23/10C$ 515
Sat 5/126:07 a.m. -
1 stop26h 33m
Sat 12/1210:55 a.m. -
1 stop16h 10m
Deal found 21/10C$ 528
Mon 9/118:35 p.m. -
1 stop11h 40m
Sat 14/111:20 p.m. -
1 stop7h 15m
Deal found 23/10C$ 539
Sun 6/126:07 a.m. -
1 stop17h 43m
Sun 13/1210:55 a.m. -
1 stop22h 00m
Deal found 22/10C$ 541
Sat 31/108:38 p.m. -
1 stop11h 37m
Sat 7/117:50 p.m. -
1 stop7h 35m
Deal found 22/10C$ 542
Fri 6/118:35 p.m. -
1 stop12h 50m
Fri 13/115:30 p.m. -
1 stop9h 55m
Deal found 21/10C$ 543
Mon 7/126:07 a.m. -
1 stop16h 38m
Mon 14/1210:55 a.m. -
1 stop22h 00m
Deal found 23/10C$ 545

Find flight deals from Santiago to Cuzco

Round-trip from

C$ 410

One-way from

C$ 237

Popular in

July

Cheapest in

March

Average price

C$ 451
Sky Airline
  • Sky Airline
  • 22/2-26/2
  • 1 total stop
  • 12h 16m total
  • Santiago to Cusco
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JetSMART
  • JetSMART
  • 2/12-31/12
  • 1 total stop
  • 7h 53m total
  • Santiago to Cusco
Search Deals
Highest demand for flights based on searches. 2% potential increase in price (C$ 15 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease (C$ 6 potential savings vs. average RT price).
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Average for round-trip flights in October 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Wed 11/11

8:35 p.m.-6:15 a.m.

1 stop11h 40m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 251

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 22/11

8:35 p.m.-7:40 a.m.

1 stop13h 05m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 261

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 5/12

9:36 a.m.-10:20 a.m.

1 stop26h 44m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 283

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 5/12

8:35 p.m.-6:15 a.m.

1 stop11h 40m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 294

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 26/12

6:07 a.m.-6:40 a.m.

1 stop26h 33m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 322

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 27/12

6:07 a.m.-9:50 p.m.

1 stop17h 43m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 375

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 22/2

1:38 p.m.-8:25 p.m.

1 stop8h 47m

Cusco Velazco Astete

Fri 26/2

6:25 p.m.-11:54 p.m.

Nonstop3h 29m

C$ 410

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 12/4

4:56 a.m.-11:15 a.m.

1 stop7h 19m

Cusco Velazco Astete

Mon 19/4

4:20 p.m.-3:56 a.m.

1 stop10h 36m

C$ 434
Quickest round-trip

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 6/2

3:10 p.m.-4:40 p.m.

Nonstop3h 30m

Cusco Velazco Astete

Thu 11/2

6:25 p.m.-11:54 p.m.

Nonstop3h 29m

C$ 447

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 9/1

3:10 p.m.-4:40 p.m.

Nonstop3h 30m

Cusco Velazco Astete

Thu 14/1

6:25 p.m.-11:54 p.m.

Nonstop3h 29m

C$ 447

Flights are sorted by cheapest round-trip flights first.

Deals found on 22/10

Showing 1-10 of 16 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

The best time to book flights from Santiago to Cusco is 75 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of C$ 385). Flying from Santiago to Cusco in July is currently the most expensive (average of C$ 466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to Cusco as you normally would.

How much does it cost to fly round-trip from Santiago to Cusco?

Airfare is typical for this route at the moment.

Santiago to Cusco flights typically cost between C$ 361 and C$ 499 in February.
The cheapest round-trip price found within the last 5 days was C$ 410 on Sky Airline (22 Feb-26 Feb).

Related info for your journey

  • How long is the flight from Santiago to Cusco?

    Sky Airline and JetSMART can get you from Santiago to Cusco in just under 7h 19m. Your travel time can differ by up to 1h 28m. The distance from Santiago to Cusco is about 2210 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Cusco (average of C$ 385). Flying from Santiago to Cusco in July is currently the most expensive (average of C$ 466). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Urubamba
Ollantaytambo

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santiago to Cuzco

Santiago to Lima flights

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