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Cheap flights from Santiago to Cusco from C$ 167

SCL — CUZ
7 Oct — 14 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Cuzco

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Cuzco

Tue 1/1210:12 p.m. -
1 stop14h 11m
Tue 8/128:51 p.m. -
1 stop22h 12m
Deal found 4/9C$ 343
Sun 18/106:53 a.m. -
1 stop15h 42m
Mon 26/109:15 p.m. -
1 stop13h 26m
Deal found 2/9C$ 353
Mon 7/1210:12 p.m. -
1 stop12h 16m
Wed 9/127:56 a.m. -
1 stop11h 07m
Deal found 4/9C$ 362
Sat 17/106:12 a.m. -
1 stop16h 48m
Sat 24/107:10 a.m. -
1 stop19h 58m
Deal found 3/9C$ 364
Fri 30/108:33 p.m. -
1 stop13h 07m
Tue 3/1112:10 p.m. -
1 stop8h 25m
Deal found 7/9C$ 365
Thu 22/106:17 a.m. -
1 stop15h 23m
Thu 29/107:15 a.m. -
1 stop19h 48m
Deal found 7/9C$ 368
Fri 16/106:12 a.m. -
1 stop11h 23m
Thu 22/108:35 a.m. -
1 stop18h 33m
Deal found 3/9C$ 369
Wed 4/117:00 a.m. -
1 stop9h 25m
Tue 10/1112:10 p.m. -
1 stop8h 25m
Deal found 7/9C$ 371
Wed 23/91:55 a.m. -
2 stops19h 55m
Thu 1/1010:45 a.m. -
1 stop9h 51m
Deal found 3/9C$ 375
Sun 1/116:07 a.m. -
1 stop17h 43m
Sun 8/1110:25 p.m. -
1 stop28h 38m
Deal found 3/9C$ 386
Sun 4/106:12 a.m. -
1 stop11h 38m
Fri 9/1010:30 p.m. -
1 stop28h 38m
Deal found 3/9C$ 398
Tue 20/105:52 a.m. -
1 stop16h 03m
Tue 27/107:55 a.m. -
1 stop18h 33m
Deal found 5/9C$ 403

Find flight deals from Santiago to Cuzco

Round-trip from

C$ 343

One-way from

C$ 167

Popular in

July

Cheapest in

November

Average price

C$ 448
JetSMART
  • JetSMART
  • 1/12-10/12
  • 2 total stops
  • 29h 08m total
  • Santiago to Cusco
Search Deals
JetSMART
  • JetSMART
  • 1/12-31/12
  • 1 total stop
  • 11h 11m total
  • Santiago to Cusco
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (C$ 30 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (C$ 8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Cusco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Tue 1/12

10:12 p.m.-7:23 a.m.

1 stop11h 11m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 167

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sun 22/11

8:35 p.m.-7:35 a.m.

1 stop13h 00m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 170

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Sat 21/11

8:35 p.m.-6:15 a.m.

1 stop11h 40m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 170

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Thu 28/1

11:27 a.m.-12:08 p.m.

1 stop26h 41m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 205

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Wed 23/12

10:12 p.m.-12:03 p.m.

1 stop15h 51m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 273
Quickest round-trip

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Tue 15/9

5:47 a.m.-10:40 a.m.

1 stop6h 53m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 284

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Mon 21/12

10:12 p.m.-8:28 a.m.

1 stop12h 16m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 284

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Tue 17/11

9:13 a.m.-8:45 p.m.

2 stops37h 32m

Cusco Velazco Astete

Wed 31/12

12:00 a.m.-2:00 a.m.

Nonstop0h 00m

C$ 296

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Fri 16/10

6:12 a.m.-3:35 p.m.

1 stop11h 23m

Cusco Velazco Astete

Thu 22/10

8:35 a.m.-5:08 a.m.

1 stop18h 33m

C$ 369

SantiagoCusco

SCL Santiago Arturo Merino Benitez - CUZ Cusco Velazco Astete

SCLCUZ

Santiago Arturo Merino Benitez

Tue 22/9

1:35 a.m.-4:55 p.m.

2 stops17h 20m

Cusco Velazco Astete

Mon 28/9

8:30 p.m.-2:35 p.m.

1 stop16h 05m

C$ 418

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/9

Showing 1-10 of 16 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Cuzco

Have a flexible travel schedule? Discover the best time to fly to Cuzco from Santiago with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Cusco

How far ahead should I book a flight from Santiago to Cusco?

The best time to book flights from Santiago to Cusco is 75 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Santiago to Cusco?

Currently, November is the cheapest month in which you can book a flight from Santiago to Cusco (average of C$ 351). Flying from Santiago to Cusco in July is currently the most expensive (average of C$ 457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to CUZ?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to Cusco as you normally would.

How much does it cost to fly round-trip from Santiago to Cusco?

Airfare is below average for this route at the moment.

Santiago to Cusco flights typically cost between C$ 398 and C$ 528 in December.
The cheapest round-trip price found within the last 5 days was C$ 343 on JetSMART (1 Dec-10 Dec).

Related info for your journey

  • How long is the flight from Santiago to Cusco?

    JetSMART can get you from Santiago to Cusco in just under 17h 43m. Your travel time can differ by up to . The distance from Santiago to Cusco is about 2210 km.

  • Can I find deals for flights from Santiago to Cuzco that include hotel bookings?

    Yes. In addition to deals on Santiago to Cuzco flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Cuzco?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Cuzco.

  • Can I find deals for business class flights from Santiago to Cuzco?

    Yes. Cheapflights offers flight deals from Santiago to Cuzco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Cusco?

    Currently, November is the cheapest month in which you can book a flight from Santiago to Cusco (average of C$ 351). Flying from Santiago to Cusco in July is currently the most expensive (average of C$ 457). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Cusco?

Book flights to Cusco if you plan to visit one of these locations
Urubamba
Ollantaytambo

Browse thousands of different options on Cheapflights for your next trip

Alternative routes for Santiago to Cuzco

Santiago to Lima flights

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