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Cheap flights from Cusco to Santiago from C$ 241

CUZ — SCL
27 Nov — 4 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Cuzco to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Cuzco to Santiago

Thu 19/1112:55 p.m. -
1 stop14h 05m
Sun 22/116:07 a.m. -
1 stop26h 23m
Deal found 23/10C$ 556
Thu 19/116:55 a.m. -
1 stop13h 40m
Sun 22/117:00 a.m. -
1 stop12h 55m
Deal found 26/10C$ 563

Find flight deals from Cuzco to Santiago

Round-trip from

C$ 556

One-way from

C$ 241

Popular in

November

Cheapest in

December

Average price

C$ 518
JetSMART
  • JetSMART
  • 19/11-22/11
  • 2 total stops
  • 40h 28m total
  • Cusco to Santiago
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Sky Airline
  • Sky Airline
  • 19/2-31/12
  • Nonstop
  • 3h 29m total
  • Cusco to Santiago
Search Deals
Highest demand for flights based on searches. 8% potential increase in price (C$ 63 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease (C$ 38 potential savings vs. average RT price).
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Average for round-trip flights in October 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Cusco to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Fri 19/2

6:25 p.m.-11:54 p.m.

Nonstop3h 29m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 241

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Fri 20/11

12:10 p.m.-10:35 p.m.

1 stop8h 25m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 255

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Thu 19/11

6:55 a.m.-10:35 p.m.

1 stop13h 40m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 255

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Thu 19/11

12:55 p.m.-5:00 a.m.

1 stop14h 05m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 258

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Thu 19/11

12:05 a.m.-9:48 p.m.

2 stops19h 43m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 288
Quickest round-trip

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Fri 20/11

11:30 a.m.-4:45 p.m.

Nonstop3h 15m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 306

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Fri 19/2

9:30 p.m.-10:46 p.m.

1 stop23h 16m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 307

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Thu 19/11

12:55 p.m.-5:00 a.m.

1 stop14h 05m

Santiago Arturo Merino Benitez

Sun 22/11

6:07 a.m.-6:30 a.m.

1 stop26h 23m

C$ 556

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Thu 19/11

6:55 a.m.-10:35 p.m.

1 stop13h 40m

Santiago Arturo Merino Benitez

Sun 22/11

7:00 a.m.-5:55 p.m.

1 stop12h 55m

C$ 563

CuscoSantiago

CUZ Cusco Velazco Astete - SCL Santiago Arturo Merino Benitez

CUZSCL

Cusco Velazco Astete

Tue 16/2

10:00 a.m.-1:12 a.m.

2 stops37h 12m

Santiago Arturo Merino Benitez

Tue 23/2

9:13 a.m.-8:45 p.m.

2 stops37h 32m

C$ 780

Flights are sorted by cheapest round-trip flights first.

Deals found on 27/10

Sorted by cheapest first

Best time to book a flight from Cuzco to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Cuzco with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Cusco to Santiago

How far ahead should I book a flight from Cusco to Santiago?

The best time to book flights from Cusco to Santiago is 47 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Cusco to Santiago?

Currently, December is the cheapest month in which you can book a flight from Cusco to Santiago (average of C$ 330). Flying from Cusco to Santiago in November is currently the most expensive (average of C$ 779). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CUZ to SCL?

When flying from Cusco to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Cusco to Santiago?

Airfare is typical for this route at the moment.

Cusco to Santiago flights typically cost between C$ 417 and C$ 804 in November.
The cheapest round-trip price found within the last 5 days was C$ 556 on JetSMART (19 Nov-22 Nov).

Related info for your journey

  • How popular is this Cusco to Santiago flight route?

    This flight path from Cusco Velazco Astete to Santiago Arturo Merino Benitez was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Cusco to Santiago?

    JetSMART and Sky Airline can get you from Cusco to Santiago in just under 13h 40m. Your travel time can differ by up to 25m. Airlines will cover a distance of 2210 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • Can I find deals for flights from Cuzco to Santiago that include hotel bookings?

    Yes. In addition to deals on Cuzco to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cuzco to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cuzco to Santiago.

  • Can I find deals for business class flights from Cuzco to Santiago?

    Yes. Cheapflights offers flight deals from Cuzco to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cusco to Santiago?

    Currently, December is the cheapest month in which you can book a flight from Cusco to Santiago (average of C$ 330). Flying from Cusco to Santiago in November is currently the most expensive (average of C$ 779). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

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Alternative routes for Cuzco to Santiago

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