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Cheap flights from Cali to Santo Domingo from C$ 458

CLO — SDQ
10 Oct — 17 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Cali to Santo Domingo

Enter your travel dates to find the best prices.

Cheapest flights from Cali to Santo Domingo

Thu 24/912:08 p.m. -
1 stop22h 34m
Sun 25/107:07 p.m. -
1 stop16h 55m
Deal found 9/9C$ 583
Thu 29/104:40 a.m. -
1 stop7h 32m
Thu 29/107:07 p.m. -
1 stop16h 55m
Deal found 7/9C$ 598
Sun 20/912:08 p.m. -
1 stop21h 47m
Thu 1/108:47 a.m. -
1 stop15h 50m
Deal found 9/9C$ 633
Thu 10/93:12 p.m. -
1 stop21h 01m
Mon 14/912:12 p.m. -
1 stop6h 09m
Deal found 7/9C$ 652
Mon 14/912:08 p.m. -
1 stop9h 48m
Fri 18/912:12 p.m. -
1 stop6h 09m
Deal found 10/9C$ 654
Mon 5/106:36 p.m. -
1 stop6h 49m
Mon 12/106:41 p.m. -
1 stop17h 25m
Deal found 7/9C$ 676
Mon 5/1012:06 p.m. -
1 stop9h 50m
Sun 11/106:06 a.m. -
1 stop9h 04m
Deal found 9/9C$ 767
Tue 6/108:46 a.m. -
1 stop6h 28m
Mon 12/106:41 p.m. -
1 stop20h 29m
Deal found 7/9C$ 768

Find flight deals from Cali to Santo Domingo

Round-trip from

C$ 583

One-way from

C$ 458

Popular in

April

Cheapest in

February

Average price

C$ 550
Copa Airlines
  • Copa Airlines
  • 5/11-9/11
  • 2 total stops
  • 16h 04m total
  • Cali to Santo Domingo
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Copa Airlines
  • Copa Airlines
  • 3/10-31/12
  • 1 total stop
  • 22h 35m total
  • Cali to Santo Domingo
Search Deals
Highest demand for flights based on searches. 3% potential increase in price (C$ 27 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease (C$ 6 potential savings vs. average RT price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Cali to Santo Domingo that are best for you.

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Route

Depart

Return

Price

Cheapest round-trip

CaliSanto Domingo

CLO Cali Alfonso B. Aragon Intl - SDQ Santo Domingo Las Americas

CLOSDQ

Cali Alfonso B. Aragon Intl

Sat 3/10

12:06 p.m.-11:41 a.m.

1 stop22h 35m

Santo Domingo Las Americas

Wed 31/12

12:00 a.m.-11:30 p.m.

Nonstop0h 00m

C$ 458

CaliSanto Domingo

CLO Cali Alfonso B. Aragon Intl - SDQ Santo Domingo Las Americas

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 24/9

12:08 p.m.-11:42 a.m.

1 stop22h 34m

Santo Domingo Las Americas

Wed 30/9

2:16 p.m.-11:06 a.m.

1 stop21h 50m

C$ 583

CaliSanto Domingo

CLO Cali Alfonso B. Aragon Intl - SDQ Santo Domingo Las Americas

CLOSDQ

Cali Alfonso B. Aragon Intl

Mon 9/11

3:14 p.m.-1:10 p.m.

1 stop20h 56m

Santo Domingo Las Americas

Mon 16/11

8:55 a.m.-5:32 p.m.

1 stop9h 37m

C$ 583

CaliSanto Domingo

CLO Cali Alfonso B. Aragon Intl - SDQ Santo Domingo Las Americas

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 24/9

12:08 p.m.-11:42 a.m.

1 stop22h 34m

Santo Domingo Las Americas

Sun 25/10

7:07 p.m.-11:02 a.m.

1 stop16h 55m

C$ 583
Quickest round-trip

CaliSanto Domingo

CLO Cali Alfonso B. Aragon Intl - SDQ Santo Domingo Las Americas

CLOSDQ

Cali Alfonso B. Aragon Intl

Fri 30/10

12:09 p.m.-10:56 p.m.

1 stop9h 47m

Santo Domingo Las Americas

Fri 6/11

7:06 p.m.-11:32 p.m.

1 stop5h 26m

C$ 583

CaliSanto Domingo

CLO Cali Alfonso B. Aragon Intl - SDQ Santo Domingo Las Americas

CLOSDQ

Cali Alfonso B. Aragon Intl

Tue 22/9

3:12 p.m.-10:56 p.m.

1 stop6h 44m

Santo Domingo Las Americas

Mon 5/10

12:42 p.m.-11:06 a.m.

1 stop23h 24m

C$ 583

CaliSanto Domingo

CLO Cali Alfonso B. Aragon Intl - SDQ Santo Domingo Las Americas

CLOSDQ

Cali Alfonso B. Aragon Intl

Wed 14/10

6:06 a.m.-2:25 a.m.

1 stop19h 19m

Santo Domingo Las Americas

Fri 16/10

8:47 a.m.-5:52 p.m.

1 stop10h 05m

C$ 583

CaliSanto Domingo

CLO Cali Alfonso B. Aragon Intl - SDQ Santo Domingo Las Americas

CLOSDQ

Cali Alfonso B. Aragon Intl

Thu 8/10

6:25 p.m.-1:12 p.m.

1 stop17h 47m

Santo Domingo Las Americas

Wed 14/10

6:41 p.m.-11:06 a.m.

1 stop17h 25m

C$ 583

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/9

Sorted by cheapest first

Best time to book a flight from Cali to Santo Domingo

Have a flexible travel schedule? Discover the best time to fly to Santo Domingo from Cali with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Cali to Santo Domingo

How far ahead should I book a flight from Cali to Santo Domingo?

The price you pay for your flight from Cali to Santo Domingo may vary depending on when you book. For the best chance of a lower fare, look to book 11 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Cali to Santo Domingo?

Currently, February is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of C$ 505). Flying from Cali to Santo Domingo in April is currently the most expensive (average of C$ 601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Cali to Santo Domingo?

Airfare is above average for this route at the moment.

Cali to Santo Domingo flights typically cost between C$ 518 and C$ 572 in September.
The cheapest round-trip price found within the last 5 days was C$ 583 on Copa Airlines (24 Sep-25 Oct).

Related info for your journey

  • How long is the flight from Cali to Santo Domingo?

    Airlines like Copa Airlines fly from Cali to Santo Domingo in about 22h 34m. The time it takes to get you to your destination can typically vary by up to . The distance from Cali to Santo Domingo is about 1807 km.

  • Can I find deals for flights from Cali to Santo Domingo that include hotel bookings?

    Yes. In addition to deals on Cali to Santo Domingo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cali to Santo Domingo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cali to Santo Domingo.

  • Can I find deals for business class flights from Cali to Santo Domingo?

    Yes. Cheapflights offers flight deals from Cali to Santo Domingo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cali to Santo Domingo?

    Currently, February is the cheapest month in which you can book a flight from Cali to Santo Domingo (average of C$ 505). Flying from Cali to Santo Domingo in April is currently the most expensive (average of C$ 601). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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