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Cheap flights from Quito to Santiago from C$ 312

UIO — SCL
21 Oct — 28 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Quito to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Quito to Santiago

Wed 2/124:50 p.m. -
1 stop10h 13m
Fri 11/126:07 a.m. -
1 stop11h 57m
Deal found 16/9C$ 561
Wed 2/124:50 p.m. -
1 stop10h 13m
Mon 7/126:07 a.m. -
1 stop11h 57m
Deal found 17/9C$ 562
Mon 2/114:50 p.m. -
1 stop10h 13m
Mon 9/116:07 a.m. -
1 stop11h 57m
Deal found 18/9C$ 607
Fri 6/114:50 p.m. -
1 stop10h 13m
Fri 13/116:07 a.m. -
1 stop11h 57m
Deal found 17/9C$ 618
Mon 23/114:50 p.m. -
1 stop10h 13m
Fri 27/116:07 a.m. -
1 stop11h 57m
Deal found 21/9C$ 619
Fri 30/104:50 p.m. -
1 stop9h 18m
Wed 4/116:07 a.m. -
1 stop11h 57m
Deal found 17/9C$ 621
Sun 15/114:50 p.m. -
1 stop10h 13m
Sun 22/116:07 a.m. -
1 stop11h 57m
Deal found 17/9C$ 625
Wed 23/124:50 p.m. -
1 stop10h 13m
Mon 18/16:07 a.m. -
1 stop11h 57m
Deal found 18/9C$ 638
Wed 4/114:50 p.m. -
1 stop10h 13m
Wed 11/116:07 a.m. -
1 stop11h 57m
Deal found 18/9C$ 649
Fri 23/104:48 p.m. -
1 stop10h 20m
Sun 8/116:07 a.m. -
1 stop11h 57m
Deal found 18/9C$ 653
Mon 5/104:48 p.m. -
1 stop10h 00m
Tue 22/1212:32 p.m. -
1 stop29h 32m
Deal found 16/9C$ 657

Find flight deals from Quito to Santiago

Round-trip from

C$ 561

One-way from

C$ 312

Popular in

February

Cheapest in

June

Average price

C$ 543
JetSMART
  • JetSMART
  • 2/12-11/12
  • 2 total stops
  • 22h 10m total
  • Quito to Santiago
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JetSMART
  • JetSMART
  • 16/12-31/12
  • 1 total stop
  • 10h 13m total
  • Quito to Santiago
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (C$ 84 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (C$ 21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Quito to Santiago that are best for you.

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Quickest round-trip

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 16/12

4:50 p.m.-5:03 a.m.

1 stop10h 13m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 312

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sun 22/11

4:50 p.m.-5:03 a.m.

1 stop10h 13m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 317

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Wed 25/11

4:50 p.m.-5:03 a.m.

1 stop10h 13m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 317

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sun 29/11

4:50 p.m.-5:03 a.m.

1 stop10h 13m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 317

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sun 6/12

4:50 p.m.-2:20 a.m.

2 stops31h 30m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 404

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 16/10

10:25 a.m.-5:45 a.m.

2 stops17h 20m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 515

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Thu 15/10

2:15 p.m.-5:45 a.m.

1 stop13h 30m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 529

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sun 1/11

6:36 p.m.-12:19 a.m.

1 stop27h 43m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 554

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Sun 6/12

4:50 p.m.-10:53 a.m.

1 stop16h 03m

Santiago Arturo Merino Benitez

Fri 11/12

6:07 a.m.-4:04 p.m.

1 stop11h 57m

C$ 561

QuitoSantiago

UIO Quito Mariscal Sucr - SCL Santiago Arturo Merino Benitez

UIOSCL

Quito Mariscal Sucr

Fri 4/12

4:50 p.m.-6:01 p.m.

1 stop23h 11m

Santiago Arturo Merino Benitez

Tue 8/12

12:32 p.m.-4:04 p.m.

1 stop29h 32m

C$ 561

Flights are sorted by cheapest round-trip flights first.

Deals found on 17/9

Showing 1-10 of 21 resultsSorted by cheapest first
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Best time to book a flight from Quito to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Quito with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Quito to Santiago

How far ahead should I book a flight from Quito to Santiago?

To ensure you get the cheapest price possible for a flight from Quito to Santiago, you should look to book at least 68 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Quito to Santiago?

Currently, June is the cheapest month in which you can book a flight from Quito to Santiago (average of C$ 505). Flying from Quito to Santiago in February is currently the most expensive (average of C$ 730). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Quito to Santiago?

Airfare is typical for this route at the moment.

Quito to Santiago flights typically cost between C$ 367 and C$ 774 in December.
The cheapest round-trip price found within the last 5 days was C$ 561 on JetSMART (2 Dec-11 Dec).

Related info for your journey

  • How long is the flight from Quito to Santiago?

    For as low as C$ 561, JetSMART can have you in Santiago from Quito in 16h 03m. The distance from Quito to Santiago is about 3780 km.

  • Can I find deals for flights from Quito to Santiago that include hotel bookings?

    Yes. In addition to deals on Quito to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Quito to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Quito to Santiago.

  • Can I find deals for business class flights from Quito to Santiago?

    Yes. Cheapflights offers flight deals from Quito to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Quito to Santiago?

    Currently, June is the cheapest month in which you can book a flight from Quito to Santiago (average of C$ 505). Flying from Quito to Santiago in February is currently the most expensive (average of C$ 730). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

Book flights to Santiago if you plan to visit one of these locations
Valparaíso
Viña del Mar

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