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Cheap flights from Mexico City to Santa Cruz de la Sierra from C$ 705

MEX — VVI
18 Oct — 25 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Mexico City to Santa Cruz de la Sierra

Enter your travel dates to find the best prices.

Cheapest flights from Mexico City to Santa Cruz de la Sierra

Mon 12/102:10 a.m. -
1 stop18h 34m
Sat 21/1111:41 a.m. -
1 stop9h 39m
Deal found 18/9C$ 938
Mon 9/113:25 a.m. -
1 stop22h 12m
Thu 26/1111:41 a.m. -
1 stop12h 44m
Deal found 17/9C$ 1,106
Sun 29/113:25 a.m. -
1 stop17h 13m
Thu 14/111:53 a.m. -
1 stop14h 22m
Deal found 17/9C$ 1,212
Mon 28/93:10 p.m. -
3 stops38h 46m
Mon 23/115:30 a.m. -
2 stops16h 45m
Deal found 16/9C$ 1,718
Tue 17/115:40 a.m. -
2 stops19h 57m
Sat 21/1111:49 a.m. -
2 stops14h 21m
Deal found 15/9C$ 6,072

Find flight deals from Mexico City to Santa Cruz de la Sierra

Round-trip from

C$ 938

One-way from

C$ 705

Popular in

December

Cheapest in

April

Average price

C$ 852
Copa Airlines
  • Copa Airlines
  • 12/10-21/11
  • 2 total stops
  • 28h 13m total
  • Mexico City to Santa Cruz de la Sierra
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23/9-31/12
  • 23/9-31/12
  • 2 total stops
  • 17h 50m total
  • Mexico City to Santa Cruz de la Sierra
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (C$ 83 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 25 potential savings vs. average RT price).
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Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Mexico City to Santa Cruz de la Sierra that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Wed 23/9

8:45 a.m.-4:35 a.m.

2 stops17h 50m

Santa Cruz de la Sierra Viru Viru Intl

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 705

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Thu 15/10

2:10 a.m.-3:38 a.m.

1 stop23h 28m

Santa Cruz de la Sierra Viru Viru Intl

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 835
Quickest round-trip

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Mon 1/3

1:50 p.m.-2:40 a.m.

1 stop10h 50m

Santa Cruz de la Sierra Viru Viru Intl

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 868

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Tue 2/3

1:50 p.m.-2:40 a.m.

1 stop10h 50m

Santa Cruz de la Sierra Viru Viru Intl

Wed 31/12

12:00 a.m.-10:00 p.m.

Nonstop0h 00m

C$ 868

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Mon 12/10

2:10 a.m.-10:44 p.m.

1 stop18h 34m

Santa Cruz de la Sierra Viru Viru Intl

Sat 21/11

11:41 a.m.-7:20 p.m.

1 stop9h 39m

C$ 938

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Wed 3/2

9:10 a.m.-10:42 p.m.

1 stop11h 32m

Santa Cruz de la Sierra Viru Viru Intl

Thu 11/2

1:18 a.m.-12:15 a.m.

1 stop24h 57m

C$ 974

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Mon 9/11

3:25 a.m.-3:37 a.m.

1 stop22h 12m

Santa Cruz de la Sierra Viru Viru Intl

Thu 26/11

11:41 a.m.-10:25 p.m.

1 stop12h 44m

C$ 1,106

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Sun 29/11

3:25 a.m.-10:38 p.m.

1 stop17h 13m

Santa Cruz de la Sierra Viru Viru Intl

Thu 14/1

11:53 a.m.-12:15 a.m.

1 stop14h 22m

C$ 1,212

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Fri 13/11

1:01 a.m.-4:35 a.m.

2 stops25h 34m

Santa Cruz de la Sierra Viru Viru Intl

Sun 22/11

5:30 a.m.-8:15 p.m.

2 stops16h 45m

C$ 1,241

Mexico CitySanta Cruz de la Sierra

MEX Mexico City Benito Juarez - VVI Santa Cruz de la Sierra Viru Viru Intl

MEXVVI

Mexico City Benito Juarez

Fri 8/1

3:30 p.m.-3:44 a.m.

1 stop10h 14m

Santa Cruz de la Sierra Viru Viru Intl

Sat 9/1

1:14 a.m.-10:25 p.m.

1 stop23h 11m

C$ 1,248

Flights are sorted by cheapest round-trip flights first.

Deals found on 16/9

Sorted by cheapest first

Best time to book a flight from Mexico City to Santa Cruz de la Sierra

Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Mexico City with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Santa Cruz de la Sierra

How far ahead should I book a flight from Mexico City to Santa Cruz de la Sierra?

Booking 84 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mexico City to Santa Cruz de la Sierra. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mexico City to Santa Cruz de la Sierra?

Currently, April is the cheapest month in which you can book a flight from Mexico City to Santa Cruz de la Sierra (average of C$ 838). Flying from Mexico City to Santa Cruz de la Sierra in December is currently the most expensive (average of C$ 1,138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Mexico City to Santa Cruz de la Sierra?

Airfare is typical for this route at the moment.

Mexico City to Santa Cruz de la Sierra flights typically cost between C$ 796 and C$ 964 in October.
The cheapest round-trip price found within the last 5 days was C$ 938 on Copa Airlines (12 Oct-21 Nov).

Related info for your journey

  • How long is the flight from Mexico City to Santa Cruz de la Sierra?

    Copa Airlines can get you from Mexico City to Santa Cruz de la Sierra in just under 18h 34m. Your travel time can differ by up to . Airlines will cover a distance of 5687 km.

  • Can I find deals for flights from Mexico City to Santa Cruz de la Sierra that include hotel bookings?

    Yes. In addition to deals on Mexico City to Santa Cruz de la Sierra flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Santa Cruz de la Sierra?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Santa Cruz de la Sierra.

  • Can I find deals for business class flights from Mexico City to Santa Cruz de la Sierra?

    Yes. Cheapflights offers flight deals from Mexico City to Santa Cruz de la Sierra by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Santa Cruz de la Sierra?

    Currently, April is the cheapest month in which you can book a flight from Mexico City to Santa Cruz de la Sierra (average of C$ 838). Flying from Mexico City to Santa Cruz de la Sierra in December is currently the most expensive (average of C$ 1,138). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Santa Cruz de la Sierra Viru Viru Intl Airport car rentals
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