Cheap flights from Mexico City to Santa Cruz de la Sierra from C$ 477
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 23/9. Fares are subject to change and may not be available on all flights or dates of travel.
Cheap flight deals from Mexico City to Santa Cruz de la Sierra
Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Santa Cruz de la Sierra (VVI). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 5 September 2025.
Round-trip from | C$ 709 |
---|---|
One-way from | C$ 477 |
Popular in | December |
Cheapest in | May |
Average price | C$ 808 |
Find flight deals from Mexico City to Santa Cruz de la Sierra
Cheapest flights from Mexico City to Santa Cruz de la SierraExplore the most affordable flight options available from Mexico City to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5 September 2025.
Explore the most affordable flight options available from Mexico City to Santa Cruz de la Sierra. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5 September 2025.
Cheapflights Fare Finder
Use the filters below to find and compare flights from Mexico City to Santa Cruz de la Sierra that are best for you.
Fly from
Fly to
Route
Depart
Return
Price
Mexico CitySanta Cruz de la Sierra
MEX - VVI
MEXVVI
Mexico City Benito Juarez
Tue 3/3
4:00 p.m.-4:35 a.m.
1 stop10h 35m
Santa Cruz de la Sierra Viru Viru Intl
Sat 21/3
5:25 a.m.-8:00 p.m.
2 stops16h 35m
Mexico CitySanta Cruz de la Sierra
MEX - VVI
MEXVVI
Mexico City Benito Juarez
Sun 30/11
10:05 p.m.-4:35 a.m.
2 stops28h 30m
Santa Cruz de la Sierra Viru Viru Intl
Sun 14/12
5:25 a.m.-1:50 p.m.
1 stop10h 25m
Mexico CitySanta Cruz de la Sierra
MEX - VVI
MEXVVI
Mexico City Benito Juarez
Tue 14/10
8:40 a.m.-4:35 a.m.
2 stops17h 55m
Santa Cruz de la Sierra Viru Viru Intl
Tue 21/10
5:20 a.m.-1:50 p.m.
1 stop10h 30m
Mexico CitySanta Cruz de la Sierra
MEX - VVI
MEXVVI
Mexico City Benito Juarez
Wed 1/10
3:30 p.m.-3:36 a.m.
1 stop10h 06m
Santa Cruz de la Sierra Viru Viru Intl
Thu 16/10
11:59 a.m.-1:00 a.m.
1 stop15h 01m
Mexico CitySanta Cruz de la Sierra
MEX - VVI
MEXVVI
Mexico City Benito Juarez
Wed 8/10
3:10 p.m.-4:35 a.m.
1 stop11h 25m
Santa Cruz de la Sierra Viru Viru Intl
Wed 15/10
5:20 a.m.-4:55 a.m.
2 stops25h 35m
Mexico CitySanta Cruz de la Sierra
MEX - VVI
MEXVVI
Mexico City Benito Juarez
Thu 2/10
5:50 a.m.-10:40 p.m.
1 stop14h 50m
Santa Cruz de la Sierra Viru Viru Intl
Tue 14/10
11:59 a.m.-12:15 a.m.
1 stop14h 16m
Mexico CitySanta Cruz de la Sierra
MEX - VVI
MEXVVI
Mexico City Benito Juarez
Sat 4/10
5:50 a.m.-10:40 p.m.
1 stop14h 50m
Santa Cruz de la Sierra Viru Viru Intl
Tue 14/10
11:59 a.m.-12:15 a.m.
1 stop14h 16m
Mexico CitySanta Cruz de la Sierra
MEX - VVI
MEXVVI
Mexico City Benito Juarez
Sat 4/10
9:40 p.m.-4:35 a.m.
2 stops28h 55m
Santa Cruz de la Sierra Viru Viru Intl
Wed 8/10
5:20 a.m.-4:55 a.m.
2 stops25h 35m
Mexico CitySanta Cruz de la Sierra
MEX - VVI
MEXVVI
Mexico City Benito Juarez
Tue 23/9
1:40 a.m.-10:25 p.m.
1 stop18h 45m
Best time to book a flight from Mexico City to Santa Cruz de la Sierra
Have a flexible travel schedule? Discover the best time to fly to Santa Cruz de la Sierra from Mexico City with our price prediction graph.
Cheapflights Insights
Everything you need to know about your flight from Mexico City to Santa Cruz de la Sierra
How far ahead should I book a flight from Mexico City to Santa Cruz de la Sierra?
Booking 56 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mexico City to Santa Cruz de la Sierra. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
Related info for your journey
Find useful and relevant information for your journey from Mexico City to Santa Cruz de la Sierra. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Why should you use Cheapflights to find cheap flight tickets from Mexico City to Santa Cruz de la Sierra?
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