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Cheap flights from Santa Cruz de la Sierra to Mexico City from C$ 528

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/3. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — MEX
4 Apr — 11 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santa Cruz de la Sierra to Mexico City

Enter your travel dates to find the best prices.

Cheapest flights from Santa Cruz de la Sierra to Mexico City
Explore the most affordable flight options available from Santa Cruz de la Sierra to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5 March 2026.

Tue 10/311:54 a.m.
VVI
-
MEX
1 stop12h 11m
Copa Airlines
Sat 4/42:10 a.m.
MEX
-
VVI
1 stop18h 32m
Copa Airlines
Deal found 28/2C$ 936
Mon 2/311:54 a.m.
VVI
-
MEX
1 stop9h 26m
Copa Airlines
Thu 5/39:25 a.m.
MEX
-
VVI
1 stop11h 25m
Copa Airlines
Deal found 1/3C$ 939
Sat 25/45:25 a.m.
VVI
-
MEX
2 stops16h 40m
Multiple Airlines
Wed 13/58:15 p.m.
MEX
-
VVI
2 stops30h 20m
Multiple Airlines
Deal found 4/3C$ 953
Mon 7/125:25 a.m.
VVI
-
MEX
2 stops26h 05m
Multiple Airlines
Sun 13/126:55 p.m.
MEX
-
VVI
2 stops31h 40m
Multiple Airlines
Deal found 2/3C$ 985
Thu 28/51:12 a.m.
VVI
-
MEX
1 stop12h 58m
Copa Airlines
Thu 18/62:10 a.m.
MEX
-
VVI
1 stop18h 28m
Copa Airlines
Deal found 2/3C$ 989
Fri 1/55:25 a.m.
VVI
-
MEX
2 stops25h 30m
Multiple Airlines
Thu 21/53:10 p.m.
MEX
-
VVI
1 stop11h 25m
Multiple Airlines
Deal found 5/3C$ 1,000
Tue 14/411:48 a.m.
VVI
-
MEX
1 stop12h 17m
Copa Airlines
Sat 13/612:25 a.m.
MEX
-
VVI
1 stop20h 13m
Copa Airlines
Deal found 28/2C$ 1,015
Thu 4/61:12 a.m.
VVI
-
MEX
1 stop19h 53m
Copa Airlines
Tue 16/69:50 a.m.
MEX
-
VVI
1 stop10h 48m
Copa Airlines
Deal found 2/3C$ 1,017
Wed 18/31:14 a.m.
VVI
-
MEX
1 stop15h 16m
Copa Airlines
Tue 24/32:00 a.m.
MEX
-
VVI
1 stop18h 50m
Copa Airlines
Deal found 3/3C$ 1,021
Fri 1/55:25 a.m.
VVI
-
MEX
2 stops16h 40m
Multiple Airlines
Fri 15/53:10 p.m.
MEX
-
VVI
1 stop11h 25m
Multiple Airlines
Deal found 2/3C$ 1,026

Find flight deals from Santa Cruz de la Sierra to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 5 March 2026.

Round-trip from

C$ 939

One-way from

C$ 528

Popular in

January

Cheapest in

August

Average price

C$ 910
Copa Airlines
  • Copa Airlines
  • 4/5-15/5
  • 2 total stops
  • 33h 41m total
  • Santa Cruz de la Sierra to Mexico City
Search Deals
Copa Airlines
  • Copa Airlines
  • 21/3
  • 1 total stop
  • 20h 06m total
  • Santa Cruz de la Sierra to Mexico City
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (C$ 66 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (C$ 13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 5 March 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/6

11:47 a.m.-12:15 a.m.

1 stop14h 28m

Mexico City Benito Juarez

Sat 6/6

12:25 a.m.-10:38 p.m.

1 stop20h 13m

C$ 939

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 28/4

1:15 a.m.-7:05 p.m.

1 stop19h 50m

Mexico City Benito Juarez

Sun 17/5

2:10 a.m.-10:38 p.m.

1 stop18h 28m

C$ 939

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 16/6

11:47 a.m.-1:00 a.m.

1 stop15h 13m

Mexico City Benito Juarez

Wed 24/6

3:30 p.m.-3:31 a.m.

1 stop10h 01m

C$ 939

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 28/5

1:12 a.m.-12:10 p.m.

1 stop12h 58m

Mexico City Benito Juarez

Thu 18/6

2:10 a.m.-10:38 p.m.

1 stop18h 28m

C$ 987

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 14/4

11:48 a.m.-10:05 p.m.

1 stop12h 17m

Mexico City Benito Juarez

Sat 13/6

12:25 a.m.-10:38 p.m.

1 stop20h 13m

C$ 989

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/6

1:12 a.m.-7:05 p.m.

1 stop19h 53m

Mexico City Benito Juarez

Mon 15/6

1:20 a.m.-10:38 p.m.

1 stop19h 18m

C$ 1,015

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sun 26/4

1:15 a.m.-12:10 p.m.

1 stop12h 55m

Mexico City Benito Juarez

Sun 10/5

1:20 a.m.-10:38 p.m.

1 stop19h 18m

C$ 1,017

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sat 21/3

1:14 a.m.-7:20 p.m.

1 stop20h 06m

C$ 528

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sat 11/4

11:48 a.m.-1:00 a.m.

1 stop15h 12m

C$ 610

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 9/4

1:15 a.m.-7:05 p.m.

1 stop19h 50m

C$ 712

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/3

Sorted by cheapest first

Best time to book a flight from Santa Cruz de la Sierra to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Mexico City

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

Currently, August is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of C$ 377). Flying from Santa Cruz de la Sierra to Mexico City in November is currently the most expensive (average of C$ 761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to Mexico City?

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Mexico City?

    For as low as C$ 939, Copa Airlines can have you in Mexico City from Santa Cruz de la Sierra in 14h 28m. Santa Cruz de la Sierra and Mexico City are separated by a distance of 5687 km.

  • Can I find deals for flights from Santa Cruz de la Sierra to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Mexico City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Mexico City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

    Currently, August is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of C$ 377). Flying from Santa Cruz de la Sierra to Mexico City in November is currently the most expensive (average of C$ 761). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Can Cheapflights find flights from Santa Cruz de la Sierra to Mexico City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Santa Cruz de la Sierra to Mexico City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Santa Cruz de la Sierra to Mexico City become cheaper?

Yes, Cheapflights offers price alerts on Santa Cruz de la Sierra to Mexico City flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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