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Cheap flights from Santa Cruz de la Sierra to Mexico City from C$ 548

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 23/7. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — MEX
8 Jun — 15 Jun1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santa Cruz de la Sierra to Mexico City

Enter your travel dates to find the best prices.

Cheapest flights from Santa Cruz de la Sierra to Mexico City
Explore the most affordable flight options available from Santa Cruz de la Sierra to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 9 May 2026.

Tue 4/811:47 a.m.
VVI
-
MEX
1 stop15h 13m
Copa Airlines
Mon 24/81:20 a.m.
MEX
-
VVI
1 stop19h 20m
Copa Airlines
Deal found 8/5C$ 982
Wed 10/61:12 a.m.
VVI
-
MEX
1 stop19h 53m
Copa Airlines
Sat 20/612:25 a.m.
MEX
-
VVI
1 stop20h 13m
Copa Airlines
Deal found 8/5C$ 1,013
Tue 4/811:47 a.m.
VVI
-
MEX
1 stop14h 28m
Copa Airlines
Mon 10/81:20 a.m.
MEX
-
VVI
1 stop19h 20m
Copa Airlines
Deal found 8/5C$ 1,032
Thu 4/611:47 a.m.
VVI
-
MEX
1 stop14h 28m
Copa Airlines
Tue 9/65:50 a.m.
MEX
-
VVI
1 stop14h 48m
Copa Airlines
Deal found 6/5C$ 1,061
Mon 1/611:47 a.m.
VVI
-
MEX
1 stop15h 13m
Copa Airlines
Sun 7/61:10 p.m.
MEX
-
VVI
1 stop12h 21m
Copa Airlines
Deal found 6/5C$ 1,110
Tue 6/1011:47 a.m.
VVI
-
MEX
1 stop15h 13m
Copa Airlines
Mon 2/111:20 a.m.
MEX
-
VVI
1 stop19h 30m
Copa Airlines
Deal found 8/5C$ 1,294
Wed 8/71:12 a.m.
VVI
-
MEX
1 stop19h 53m
Copa Airlines
Wed 15/71:20 a.m.
MEX
-
VVI
1 stop19h 20m
Copa Airlines
Deal found 9/5C$ 1,326

Find flight deals from Santa Cruz de la Sierra to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 9 May 2026.

Round-trip from

C$ 982

One-way from

C$ 548

Popular in

January

Cheapest in

September

Average price

C$ 922
Copa Airlines
  • Copa Airlines
  • 3/8-10/8
  • 2 total stops
  • 45h 08m total
  • Santa Cruz de la Sierra to Mexico City
Search Deals
Copa Airlines
  • Copa Airlines
  • 23/7
  • 1 total stop
  • 15h 13m total
  • Santa Cruz de la Sierra to Mexico City
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (C$ 52 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease (C$ 13 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 9 May 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 3/8

1:12 a.m.-1:00 a.m.

1 stop25h 48m

Mexico City Benito Juarez

Mon 10/8

1:20 a.m.-10:40 p.m.

1 stop19h 20m

C$ 982

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 4/8

11:47 a.m.-12:15 a.m.

1 stop14h 28m

Mexico City Benito Juarez

Mon 24/8

1:20 a.m.-10:40 p.m.

1 stop19h 20m

C$ 982

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sun 4/10

1:12 a.m.-7:05 p.m.

1 stop19h 53m

Mexico City Benito Juarez

Tue 13/10

1:20 a.m.-10:44 p.m.

1 stop19h 24m

C$ 982

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/6

11:47 a.m.-12:15 a.m.

1 stop14h 28m

Mexico City Benito Juarez

Mon 8/6

1:20 a.m.-10:38 p.m.

1 stop19h 18m

C$ 982
Quickest round-trip

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/8

11:47 a.m.-12:15 a.m.

1 stop14h 28m

Mexico City Benito Juarez

Mon 17/8

5:50 a.m.-10:40 p.m.

1 stop14h 50m

C$ 982

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 11/8

11:47 a.m.-12:15 a.m.

1 stop14h 28m

Mexico City Benito Juarez

Sat 15/8

12:25 a.m.-10:40 p.m.

1 stop20h 15m

C$ 982

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Wed 10/6

1:12 a.m.-7:05 p.m.

1 stop19h 53m

Mexico City Benito Juarez

Mon 15/6

9:50 a.m.-10:38 p.m.

1 stop10h 48m

C$ 982

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 10/9

11:47 a.m.-12:15 a.m.

1 stop14h 28m

Mexico City Benito Juarez

Wed 30/9

5:50 a.m.-3:38 a.m.

1 stop19h 48m

C$ 982
Cheapest one-way

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 23/7

11:47 a.m.-1:00 a.m.

1 stop15h 13m

C$ 548

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Fri 7/8

1:12 a.m.-7:05 p.m.

1 stop19h 53m

C$ 733

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/5

Showing 1-10 of 11 resultsSorted by cheapest first
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Best time to book a flight from Santa Cruz de la Sierra to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Mexico City

How far ahead should I book a flight from Santa Cruz de la Sierra to Mexico City?

The price you pay for your flight from Santa Cruz de la Sierra to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 86 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of C$ 825). Flying from Santa Cruz de la Sierra to Mexico City in January is currently the most expensive (average of C$ 1,035). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to Mexico City?

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Mexico City?

    For as low as C$ 982, Copa Airlines can have you in Mexico City from Santa Cruz de la Sierra in 25h 48m. Santa Cruz de la Sierra and Mexico City are separated by a distance of 5687 km.

  • Can I find deals for flights from Santa Cruz de la Sierra to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Mexico City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Mexico City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

    Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of C$ 825). Flying from Santa Cruz de la Sierra to Mexico City in January is currently the most expensive (average of C$ 1,035). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Why should you use Cheapflights to find cheap flight tickets from Santa Cruz de la Sierra to Mexico City?

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Can Cheapflights find flights from Santa Cruz de la Sierra to Mexico City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Santa Cruz de la Sierra to Mexico City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Santa Cruz de la Sierra to Mexico City become cheaper?

Yes, Cheapflights offers price alerts on Santa Cruz de la Sierra to Mexico City flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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