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Cheap flights from Santa Cruz de la Sierra to Mexico City from C$ 535

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/10. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — MEX
14 Sep — 21 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santa Cruz de la Sierra to Mexico City

Enter your travel dates to find the best prices.

Cheapest flights from Santa Cruz de la Sierra to Mexico City
Explore the most affordable flight options available from Santa Cruz de la Sierra to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 August 2026.

Mon 5/101:12 a.m. -
1 stop25h 48m
Mon 19/101:20 a.m. -
1 stop19h 24m
Deal found 12/8C$ 992
Tue 11/81:12 a.m. -
1 stop12h 58m
Tue 18/82:10 a.m. -
1 stop18h 30m
Deal found 11/8C$ 1,031
Mon 31/811:47 a.m. -
1 stop15h 13m
Tue 1/123:30 p.m. -
1 stop10h 12m
Deal found 12/8C$ 1,042
Thu 24/911:47 a.m. -
1 stop15h 13m
Mon 28/91:20 a.m. -
1 stop19h 24m
Deal found 14/8C$ 1,043
Tue 1/911:47 a.m. -
1 stop12h 18m
Sat 5/92:00 p.m. -
1 stop10h 30m
Deal found 11/8C$ 1,064
Thu 27/81:12 a.m. -
1 stop25h 03m
Sat 29/85:50 a.m. -
1 stop14h 50m
Deal found 13/8C$ 1,071
Thu 15/101:12 a.m. -
1 stop25h 48m
Tue 10/111:10 p.m. -
1 stop12h 27m
Deal found 11/8C$ 1,082
Thu 20/811:47 a.m. -
1 stop14h 28m
Tue 25/81:20 a.m. -
1 stop24h 15m
Deal found 14/8C$ 1,083
Mon 19/1011:47 a.m. -
1 stop14h 28m
Tue 10/111:10 p.m. -
1 stop12h 27m
Deal found 10/8C$ 1,106
Sat 15/81:12 a.m. -
1 stop25h 03m
Sat 29/812:25 a.m. -
1 stop20h 15m
Deal found 14/8C$ 1,145
Mon 24/811:47 a.m. -
1 stop15h 13m
Mon 31/85:50 a.m. -
1 stop14h 50m
Deal found 12/8C$ 1,195

Find flight deals from Santa Cruz de la Sierra to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 15 August 2026.

Round-trip from

C$ 992

One-way from

C$ 535

Popular in

June

Cheapest in

November

Average price

C$ 997
Copa Airlines
  • Copa Airlines
  • 1/10-14/10
  • 2 total stops
  • 33h 47m total
  • Santa Cruz de la Sierra to Mexico City
Search Deals
Copa Airlines
  • Copa Airlines
  • 6/10
  • 1 total stop
  • 15h 13m total
  • Santa Cruz de la Sierra to Mexico City
Search Deals
Highest demand for flights based on searches. 6% potential increase in price (C$ 102 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (C$ 32 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 15 August 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sun 27/9

1:12 a.m.-1:00 a.m.

1 stop25h 48m

Mexico City Benito Juarez

Tue 6/10

1:20 a.m.-3:38 a.m.

1 stop24h 18m

C$ 992

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Wed 11/11

1:08 a.m.-7:20 p.m.

1 stop20h 12m

Mexico City Benito Juarez

Tue 1/12

3:30 p.m.-3:42 a.m.

1 stop10h 12m

C$ 992

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 15/10

11:47 a.m.-12:10 p.m.

1 stop26h 23m

Mexico City Benito Juarez

Tue 20/10

2:10 a.m.-10:44 p.m.

1 stop18h 34m

C$ 992

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 8/10

1:12 a.m.-1:00 a.m.

1 stop25h 48m

Mexico City Benito Juarez

Sun 18/10

1:20 a.m.-3:38 a.m.

1 stop24h 18m

C$ 992

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 15/10

1:12 a.m.-1:00 a.m.

1 stop25h 48m

Mexico City Benito Juarez

Tue 10/11

1:10 p.m.-3:37 a.m.

1 stop12h 27m

C$ 1,031
Quickest round-trip

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 31/8

11:47 a.m.-10:05 p.m.

1 stop12h 18m

Mexico City Benito Juarez

Tue 1/12

1:10 p.m.-3:42 a.m.

1 stop12h 32m

C$ 1,042

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 16/11

1:08 a.m.-12:15 a.m.

1 stop25h 07m

Mexico City Benito Juarez

Sat 28/11

1:20 a.m.-10:38 p.m.

1 stop19h 18m

C$ 1,042

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 15/9

11:47 a.m.-1:00 a.m.

1 stop15h 13m

Mexico City Benito Juarez

Mon 28/9

1:20 a.m.-10:44 p.m.

1 stop19h 24m

C$ 1,042

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sun 31/1

1:18 a.m.-7:20 p.m.

1 stop20h 02m

Mexico City Benito Juarez

Sat 20/2

1:20 a.m.-10:42 p.m.

1 stop19h 22m

C$ 1,042
Cheapest one-way

Santa Cruz de la SierraMexico City

VVI Santa Cruz de la Sierra Viru Viru Intl - MEX Mexico City Benito Juarez

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 6/10

11:47 a.m.-1:00 a.m.

1 stop15h 13m

C$ 535

Flights are sorted by cheapest round-trip flights first.

Deals found on 13/8

Showing 1-10 of 14 resultsSorted by cheapest first
1
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Best time to book a flight from Santa Cruz de la Sierra to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Mexico City

How far ahead should I book a flight from Santa Cruz de la Sierra to Mexico City?

The price you pay for your flight from Santa Cruz de la Sierra to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 30 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of C$ 850). Flying from Santa Cruz de la Sierra to Mexico City in June is currently the most expensive (average of C$ 1,236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Santa Cruz de la Sierra to Mexico City?

Airfare is typical for this route at the moment.

Santa Cruz de la Sierra to Mexico City flights typically cost between C$ 936 and C$ 1,108 in October.
The cheapest round-trip price found within the last 5 days was C$ 992 on Copa Airlines (5 Oct-19 Oct).

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Mexico City?

    For as low as C$ 992, Copa Airlines can have you in Mexico City from Santa Cruz de la Sierra in 25h 48m. Santa Cruz de la Sierra and Mexico City are separated by a distance of 5687 km.

  • Can I find deals for flights from Santa Cruz de la Sierra to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Mexico City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Mexico City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

    Currently, November is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of C$ 850). Flying from Santa Cruz de la Sierra to Mexico City in June is currently the most expensive (average of C$ 1,236). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Why should you use Cheapflights to find cheap flight tickets from Santa Cruz de la Sierra to Mexico City?

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Can Cheapflights find flights from Santa Cruz de la Sierra to Mexico City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Santa Cruz de la Sierra to Mexico City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Santa Cruz de la Sierra to Mexico City become cheaper?

Yes, Cheapflights offers price alerts on Santa Cruz de la Sierra to Mexico City flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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