What’s the top layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Denver (DEN) – chosen by Cheapflights users on 32% of one-stop itineraries from Detroit Metropolitan Wayne County Airport to San Francisco on Cheapflights.

What’s the cheapest layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Atlanta (ATL) is the most affordable 1-stop option, with an average round-trip price of C$ 255.

What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to San Francisco?

Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 7h 48m.

Which airport typically offers the quickest layover for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Flights via Seattle (SEA) offer the fastest connection on this route, with an average layover time of 1h 17m.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to San Francisco

The most flights from DTW to SFO are scheduled on a Monday (13 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (8 on average).

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 112.0 mm per month. January is typically the wettest month, when rainfall can reach 112.0 mm. July is typically the driest time to visit San Francisco when rainfall is around 0.0 mm.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 17.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 11.0 C).

What are the most popular airlines that fly from Detroit Metropolitan Wayne County Airport to San Francisco?

When booking a flight from Detroit Metropolitan Wayne County Airport to San Francisco, you may want to consider flying on Delta, Frontier or United Airlines as they are the most popular for this route.

What is the cheapest day to fly round-trip from Detroit Metropolitan Wayne County Airport to San Francisco?

Flying to your destination on a Monday can be more expensive, but this shouldn’t discourage you from finding affordable options to get to San Francisco. Check prices with Cheapflights to find a great deal for your trip.

What is the cheapest month to fly from Detroit Metropolitan Wayne County Airport to San Francisco?

July can be a great time to fly to San Francisco from Detroit Metropolitan Wayne County Airport with a flight ticket averaging about C$ 700. Cheapflights users have found deals in the month of July for as cheap as C$ 211. The most expensive prices can be found in the month of January.

What airports do I use to fly from Detroit to San Francisco?

To fly from Detroit to San Francisco, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to San Francisco (SFO). Nonstop flights to San Francisco from Detroit Metropolitan Wayne County take 5h 03m on average. When it comes time to book airfare, you have a few options: there are 11 outbound flights from Detroit Metropolitan Wayne County to San Francisco offered by 4 different airlines.

Can I find deals for flights from Detroit to San Francisco that include hotel bookings?

Yes. In addition to deals on Detroit to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to San Francisco.

Can I find deals for business class flights from Detroit to San Francisco?

Yes. Cheapflights offers flight deals from Detroit to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 198+ Flights from Detroit Metropolitan Wayne County Airport to San Francisco

Q: What is the cheapest day to fly from Detroit Metropolitan Wayne County Airport to San Francisco?

Travelers seeking maximum savings on their Detroit Metropolitan Wayne County Airport to San Francisco flight should consider departing on Sunday at noon when fares are most often at their lowest. Tuesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to San Francisco are usually found in July or June, booked 90 days in advance, depart on a Sunday or Wednesday and return on a Tuesday

Cheap flight deals from Detroit to San Francisco

Round-trip from	C$ 414
One-way from	C$ 198
Popular in	January
Cheapest in	July
Average price	C$ 606
Good round-trip deal	C$ 539 or less

United Airlines
24/10-26/10
1 total stop
12h 32m total
Detroit to San Francisco

Search Deals

Southwest
5/1
1 total stop
10h 05m total
Detroit to San Francisco

Search Deals

Highest demand for flights based on searches. 19% potential increase in price (C$ 243 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 3% potential price decrease (C$ 37 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to San Francisco.

Search Deals

Find flight deals from Detroit to San Francisco

Cheapest flights from Detroit to San Francisco
Explore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 September 2025.

Fri 24/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Thu 13/117:00 a.m.SFO - DTW

1 stop6h 45mUnited Airlines

Deal found 11/9C$ 414

Thu 18/126:40 a.m.DTW - SFO

1 stop10h 14mAlaska Airlines

Wed 31/125:42 p.m.SFO - DTW

1 stop8h 38mAlaska Airlines

Deal found 11/9C$ 427

Thu 9/106:05 p.m.DTW - SFO

1 stop7h 26mUnited Airlines

Tue 14/108:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 10/9C$ 428

Wed 22/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Tue 28/106:00 a.m.SFO - DTW

1 stop7h 45mUnited Airlines

Deal found 10/9C$ 432

Tue 7/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Fri 17/1011:00 p.m.SFO - DTW

1 stop8h 07mUnited Airlines

Deal found 10/9C$ 437

Fri 28/116:25 a.m.DTW - SFO

1 stop7h 40mSouthwest

Sat 6/125:30 a.m.SFO - DTW

2 stops11h 20mSouthwest

Deal found 10/9C$ 438

Thu 13/115:35 p.m.DTW - SFO

Nonstop5h 25mUnited Airlines

Sat 15/111:31 p.m.SFO - DTW

1 stop7h 04mUnited Airlines

Deal found 10/9C$ 439

Wed 24/95:32 p.m.DTW - SFO

Nonstop5h 08mUnited Airlines

Sun 12/108:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 10/9C$ 442

Wed 24/127:49 p.m.DTW - SFO

1 stop8h 28mUnited Airlines

Mon 29/127:00 a.m.SFO - DTW

1 stop7h 17mUnited Airlines

Deal found 11/9C$ 443

Fri 21/116:00 a.m.DTW - SFO

1 stop12h 05mSouthwest

Fri 28/111:00 p.m.SFO - DTW

1 stop7h 00mSouthwest

Deal found 11/9C$ 446

Wed 24/127:10 a.m.DTW - SFO

Nonstop5h 25mUnited Airlines

Tue 30/126:00 a.m.SFO - DTW

1 stop8h 17mUnited Airlines

Deal found 11/9C$ 448

Wed 26/115:40 a.m.DTW - SFO

2 stops10h 00mSouthwest

Mon 1/129:25 p.m.SFO - DTW

1 stop12h 00mSouthwest

Deal found 10/9C$ 449

Best flights from Detroit to San Francisco
Discover carefully curated flight deals from Detroit to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 11 September 2025.

Fri 31/105:35 p.m.DTW - SFO

Nonstop5h 25mUnited Airlines

Mon 10/1111:20 p.m.SFO - DTW

1 stop7h 46mUnited Airlines

Deal found 11/9C$ 414

Thu 29/16:50 a.m.DTW - SFO

2 stops11h 05mSouthwest

Sat 14/25:30 a.m.SFO - DTW

1 stop6h 40mSouthwest

Deal found 10/9C$ 414

Wed 22/108:25 p.m.DTW - SFO

Nonstop5h 10mDelta

Sun 26/1010:57 p.m.SFO - DTW

Nonstop4h 30mDelta

Deal found 11/9C$ 455

Thu 2/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Mon 6/1010:45 p.m.SFO - DTW

1 stop8h 16mUnited Airlines

Deal found 11/9C$ 414

Wed 28/16:50 a.m.DTW - SFO

2 stops11h 05mSouthwest

Sat 14/26:40 a.m.SFO - DTW

2 stops12h 05mSouthwest

Deal found 10/9C$ 431

Wed 28/18:20 p.m.DTW - SFO

Nonstop5h 27mDelta

Sat 14/210:45 p.m.SFO - DTW

Nonstop4h 35mDelta

Deal found 10/9C$ 455

Fri 24/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Sun 26/105:10 a.m.SFO - DTW

1 stop8h 35mUnited Airlines

Deal found 11/9C$ 414

Sat 1/115:35 p.m.DTW - SFO

Nonstop5h 25mUnited Airlines

Tue 4/115:10 a.m.SFO - DTW

1 stop8h 35mUnited Airlines

Deal found 10/9C$ 414

Wed 29/109:07 a.m.DTW - SFO

1 stop7h 30mUnited Airlines

Sun 2/118:59 a.m.SFO - DTW

Nonstop4h 40mUnited Airlines

Deal found 10/9C$ 414

Thu 2/107:00 a.m.DTW - SFO

1 stop9h 35mUnited Airlines

Tue 7/108:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 11/9C$ 414

Wed 22/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Tue 28/106:00 a.m.SFO - DTW

1 stop7h 45mUnited Airlines

Deal found 10/9C$ 432

Thu 13/115:35 p.m.DTW - SFO

Nonstop5h 25mUnited Airlines

Mon 17/116:00 a.m.SFO - DTW

1 stop6h 28mUnited Airlines

Deal found 11/9C$ 439

Direct flights from Detroit to San Francisco
Explore direct flight options from Detroit to San Francisco based on user searches, and compare prices and availability for your desired travel dates. Data last updated 11 September 2025.

Wed 24/95:32 p.m.DTW - SFO

Nonstop5h 08mUnited Airlines

Sun 12/108:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 10/9C$ 442

Fri 24/108:25 p.m.DTW - SFO

Nonstop5h 10mDelta

Sun 26/1010:57 p.m.SFO - DTW

Nonstop4h 30mDelta

Deal found 11/9C$ 455

Fri 26/95:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Wed 1/108:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 10/9C$ 464

Fri 24/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Thu 13/118:59 a.m.SFO - DTW

Nonstop4h 40mUnited Airlines

Deal found 11/9C$ 475

Tue 30/97:45 p.m.DTW - SFO

Nonstop5h 03mDelta

Sat 4/1011:00 p.m.SFO - DTW

Nonstop4h 26mDelta

Deal found 11/9C$ 481

Fri 26/95:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Mon 29/98:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 11/9C$ 484

Sun 21/127:10 a.m.DTW - SFO

Nonstop5h 25mUnited Airlines

Fri 2/19:25 p.m.SFO - DTW

Nonstop4h 41mUnited Airlines

Deal found 11/9C$ 489

Thu 20/118:00 p.m.DTW - SFO

Nonstop5h 12mDelta

Wed 10/1210:45 p.m.SFO - DTW

Nonstop4h 27mDelta

Deal found 11/9C$ 497

Fri 3/107:45 p.m.DTW - SFO

Nonstop5h 03mDelta

Sun 5/1011:00 p.m.SFO - DTW

Nonstop4h 26mDelta

Deal found 11/9C$ 524

Mon 29/95:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Wed 12/118:59 a.m.SFO - DTW

Nonstop4h 40mUnited Airlines

Deal found 10/9C$ 525

Wed 15/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Sun 19/108:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 10/9C$ 532

Tue 16/127:05 a.m.DTW - SFO

Nonstop5h 25mUnited Airlines

Mon 5/19:25 p.m.SFO - DTW

Nonstop4h 41mUnited Airlines

Deal found 11/9C$ 539

Last-minute flights from Detroit to San Francisco
Discover last-minute flight deals from Detroit to San Francisco. Data last updated 11 September 2025 and is based on user searches.

Wed 24/95:32 p.m.DTW - SFO

Nonstop5h 08mUnited Airlines

Sun 12/108:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 10/9C$ 442

Fri 26/95:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Wed 1/108:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 10/9C$ 464

Sat 4/1012:16 p.m.DTW - SFO

1 stop11h 47mJetBlue

Tue 7/109:00 p.m.SFO - DTW

1 stop11h 30mJetBlue

Deal found 10/9C$ 453

Tue 7/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Fri 17/1011:00 p.m.SFO - DTW

1 stop8h 07mUnited Airlines

Deal found 10/9C$ 437

Tue 7/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Tue 14/105:15 a.m.SFO - DTW

1 stop8h 36mUnited Airlines

Deal found 11/9C$ 439

Thu 9/106:05 p.m.DTW - SFO

1 stop7h 26mUnited Airlines

Tue 14/108:55 a.m.SFO - DTW

Nonstop4h 45mUnited Airlines

Deal found 10/9C$ 428

Wed 22/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Tue 28/106:00 a.m.SFO - DTW

1 stop7h 45mUnited Airlines

Deal found 10/9C$ 432

Fri 24/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Thu 13/117:00 a.m.SFO - DTW

1 stop6h 45mUnited Airlines

Deal found 11/9C$ 414

Fri 24/108:25 p.m.DTW - SFO

Nonstop5h 10mDelta

Sun 26/1010:57 p.m.SFO - DTW

Nonstop4h 30mDelta

Deal found 11/9C$ 455

Fri 24/105:45 p.m.DTW - SFO

Nonstop5h 14mUnited Airlines

Sun 26/105:00 a.m.SFO - DTW

1 stop6h 58mUnited Airlines

Deal found 11/9C$ 459

One-way flights from Detroit to San Francisco
Search for one-way flight options from Detroit to San Francisco. Find affordable one-way fares based on user searches. Data last updated 11 September 2025.

Mon 5/12:45 p.m.DTW - SFO

1 stop10h 05mSouthwest

Deal found 11/9C$ 198

Tue 10/36:00 a.m.DTW - SFO

1 stop10h 39mJetBlue

Deal found 10/9C$ 204

Thu 25/126:40 a.m.DTW - SFO

1 stop10h 14mHawaiian Airlines

Deal found 11/9C$ 213

Tue 14/108:00 a.m.DTW - SFO

1 stop6h 40mSouthwest

Deal found 11/9C$ 215

Fri 14/116:25 a.m.DTW - SFO

2 stops10h 40mSouthwest

Deal found 11/9C$ 219

Sat 11/101:05 p.m.DTW - SFO

1 stop9h 40mSouthwest

Deal found 11/9C$ 220

Wed 26/115:40 a.m.DTW - SFO

2 stops10h 00mSouthwest

Deal found 11/9C$ 222

Sat 18/1010:25 p.m.DTW - SFO

3 stops52h 49mMultiple Airlines

Deal found 9/9C$ 224

Mon 10/112:45 p.m.DTW - SFO

2 stops10h 35mSouthwest

Deal found 11/9C$ 227

Fri 19/93:42 p.m.DTW - SFO

1 stop8h 39mFrontier

Deal found 10/9C$ 236

Sun 18/16:50 a.m.DTW - SFO

2 stops11h 05mSouthwest

Deal found 9/9C$ 241

Fri 17/1010:25 p.m.DTW - SFO

3 stops26h 04mMultiple Airlines

Deal found 10/9C$ 256

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Fri 31/10

5:35 p.m.-8:00 p.m.

Nonstop5h 25m

San Francisco

Mon 10/11

11:20 p.m.-10:06 a.m.

1 stop7h 46m

C$ 414

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Thu 29/1

6:50 a.m.-2:55 p.m.

2 stops11h 05m

San Francisco

Sat 14/2

5:30 a.m.-3:10 p.m.

1 stop6h 40m

C$ 414

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Thu 2/10

5:45 p.m.-7:59 p.m.

Nonstop5h 14m

San Francisco

Mon 6/10

10:45 p.m.-10:01 a.m.

1 stop8h 16m

C$ 414

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Fri 24/10

5:45 p.m.-7:59 p.m.

Nonstop5h 14m

San Francisco

Sun 26/10

5:10 a.m.-4:45 p.m.

1 stop8h 35m

C$ 414

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sat 1/11

5:35 p.m.-8:00 p.m.

Nonstop5h 25m

San Francisco

Tue 4/11

5:10 a.m.-4:45 p.m.

1 stop8h 35m

C$ 414

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 29/10

9:07 a.m.-1:37 p.m.

1 stop7h 30m

San Francisco

Sun 2/11

8:59 a.m.-4:39 p.m.

Nonstop4h 40m

C$ 414

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Thu 2/10

7:00 a.m.-1:35 p.m.

1 stop9h 35m

San Francisco

Tue 7/10

8:55 a.m.-4:40 p.m.

Nonstop4h 45m

C$ 414

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 28/1

6:50 a.m.-2:55 p.m.

2 stops11h 05m

San Francisco

Sat 14/2

6:40 a.m.-9:45 p.m.

2 stops12h 05m

C$ 431

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Wed 22/10

5:45 p.m.-7:59 p.m.

Nonstop5h 14m

San Francisco

Tue 28/10

6:00 a.m.-4:45 p.m.

1 stop7h 45m

C$ 432

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Thu 13/11

5:35 p.m.-8:00 p.m.

Nonstop5h 25m

San Francisco

Mon 17/11

6:00 a.m.-3:28 p.m.

1 stop6h 28m

C$ 439

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/9

Showing 1-10 of 23 results

Best time to book a flight from Detroit to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Detroit with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to San Francisco

Prices

Airlines

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

The best time to book flights from Detroit Metropolitan Wayne County Airport to San Francisco is 79 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Francisco (average of C$ 276). Flying from Detroit Metropolitan Wayne County Airport to San Francisco in December is currently the most expensive (average of C$ 368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SFO?

A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to San Francisco in the morning. If you’re flexible enough to do this you can expect to save up to 20% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing San Francisco

Check out reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Detroit Metropolitan Wayne County Airport to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,248 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,248 reviews

Southwest

8.0

Very good

4,248 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

8.0

Very good

7,960 reviews

Southwest

8.0

Very good

4,248 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

8,937 reviews

Southwest

8.0

Very good

4,248 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.8

Fair

3,177 reviews

Southwest

8.0

Very good

4,248 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What airports do I use to fly from Detroit to San Francisco?
To fly from Detroit to San Francisco, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to San Francisco (SFO). Nonstop flights to San Francisco from Detroit Metropolitan Wayne County take 5h 03m on average. When it comes time to book airfare, you have a few options: there are 11 outbound flights from Detroit Metropolitan Wayne County to San Francisco offered by 4 different airlines.
How long is the flight from Detroit Metropolitan Wayne County Airport to San Francisco?
There are many flights that can get you from Detroit Metropolitan Wayne County Airport to San Francisco in 5h 25m. Fly via United Airlines or Southwest to get the fastest option. Detroit Metropolitan Wayne County Airport and San Francisco are separated by a distance of 3335 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco round-trip?
Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to San Francisco round-trip from C$ 209. Other airlines that can offer you cheap pricing are Delta, from C$ 400, and Southwest, from C$ 427. These flights start at 71% lower than the current average price 3 months from now.
What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to San Francisco?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to San Francisco on time: KLM (79%), Korean Air (79%), ITA Airways (73%).
What are the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco?
Looking at all options, your cheapest flight can be booked for C$ 539. While the most popular route (Detroit Metropolitan Wayne County - San Francisco) can be booked for C$ 334 on average, our data indicates C$ 892 when flying from Detroit Metropolitan Wayne County Airport to San Francisco.
Can I find deals for flights from Detroit to San Francisco that include hotel bookings?
Yes. In addition to deals on Detroit to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to San Francisco.
Can I find deals for business class flights from Detroit to San Francisco?
Yes. Cheapflights offers flight deals from Detroit to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Francisco (average of C$ 276). Flying from Detroit Metropolitan Wayne County Airport to San Francisco in December is currently the most expensive (average of C$ 368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Richmond

Newark

Alameda

Redwood City

Burlingame

San Bruno

South San Francisco

Scotts Valley

Belmont

Novato

Millbrae

Santa Clara

Vallejo

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Detroit to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Frontier	CheapestC$ 209	AverageC$ 364	FlexibilityNo cancel fee	On-time62%	Search Frontier flights
Delta	CheapestC$ 400	AverageC$ 592	FlexibilityNo cancel fee	On-timeN/A	Search Delta flights
Southwest	CheapestC$ 427	AverageC$ 758	FlexibilityNo cancel fee	On-time63%	Search Southwest flights
United Airlines	CheapestC$ 539	AverageC$ 956	FlexibilityNo cancel fee	On-time69%	Search United Airlines flights

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How does Cheapflights help users find flights from Detroit to San Francisco?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to San Francisco from Detroit today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Detroit to San Francisco?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Detroit to San Francisco.

Can Cheapflights find flights from Detroit to San Francisco with no change fees?

Certainly. Search results for flights to San Francisco from Detroit shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

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Cheap flights from Detroit Metropolitan Wayne County Airport to San Francisco from C$ 198

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/1. Fares are subject to change and may not be available on all flights or dates of travel.

Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to San Francisco are usually found in July or June, booked 90 days in advance, depart on a Sunday or Wednesday and return on a Tuesday

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Find flight deals from Detroit to San Francisco

Cheapest flights from Detroit to San FranciscoExplore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 September 2025.

Explore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 September 2025.

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Best time to book a flight from Detroit to San Francisco

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Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to San Francisco

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

What is the cheapest time of day to fly from DTW to SFO?

Weekly flight availability from Detroit Metropolitan Wayne County Airport to San Francisco

What’s the top layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to San Francisco?

What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to San Francisco?

Which airport typically offers the quickest layover for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Reviews of airlines servicing San Francisco

Related info for your journey

Find useful and relevant information for your journey from Detroit to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

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What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco round-trip?

What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to San Francisco?

What are the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Can I find deals for flights from Detroit to San Francisco that include hotel bookings?

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What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

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Alternative routes for Detroit to San Francisco

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Top 4 airlines flying from Detroit to San Francisco

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Cheapest flights from Detroit to San Francisco
Explore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 11 September 2025.