Cheap flights from Detroit Metropolitan Wayne County Airport to San Francisco from C$ 224
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 19/12. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — SFO
27 Nov — 4 Dec1
Round-trip
1 adult
Economy
Round-trip
1 adult, Economy, 0 bags
Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to San Francisco are usually found in July or June, booked 79 days in advance, depart on a Sunday or Wednesday and return on a Tuesday
Cheap flight deals from Detroit to San Francisco
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to San Francisco (SFO). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 28 October 2025.
Explore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 28 October 2025.
Thu 27/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Wed 10/1211:25 a.m.SFO - DTW
Nonstop4h 39mUnited Airlines
Deal found 26/10C$ 427
Thu 4/127:25 a.m.DTW - SFO
1 stop9h 10mUnited Airlines
Sun 21/1211:35 p.m.SFO - DTW
1 stop7h 58mUnited Airlines
Deal found 28/10C$ 432
Fri 19/125:10 a.m.DTW - SFO
1 stop13h 50mSouthwest
Fri 9/15:30 a.m.SFO - DTW
1 stop9h 20mSouthwest
Deal found 27/10C$ 439
Sat 8/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Sat 15/118:59 a.m.SFO - DTW
Nonstop4h 40mUnited Airlines
Deal found 25/10C$ 446
Wed 12/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Fri 9/111:56 p.m.SFO - DTW
1 stop7h 14mUnited Airlines
Deal found 25/10C$ 460
Sat 20/127:50 a.m.DTW - SFO
1 stop26h 58mMultiple Airlines
Wed 24/129:30 p.m.SFO - DTW
1 stop29h 00mMultiple Airlines
Deal found 26/10C$ 462
Tue 25/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Fri 28/117:00 a.m.SFO - DTW
1 stop6h 45mUnited Airlines
Deal found 27/10C$ 470
Tue 11/118:00 a.m.DTW - SFO
1 stop9h 40mSouthwest
Fri 5/1210:50 a.m.SFO - DTW
1 stop6h 50mSouthwest
Deal found 26/10C$ 474
Wed 12/112:31 p.m.DTW - SFO
1 stop12h 28mJetBlue
Sun 16/119:10 p.m.SFO - DTW
1 stop10h 39mJetBlue
Deal found 28/10C$ 480
Fri 12/127:05 a.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 15/1211:25 a.m.SFO - DTW
Nonstop4h 39mUnited Airlines
Deal found 26/10C$ 481
Thu 20/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 1/1211:50 p.m.SFO - DTW
1 stop7h 05mUnited Airlines
Deal found 27/10C$ 484
Thu 4/127:00 a.m.DTW - SFO
2 stops10h 25mSouthwest
Mon 8/125:20 a.m.SFO - DTW
2 stops9h 30mSouthwest
Deal found 26/10C$ 488
Best flights from Detroit to San Francisco
Discover carefully curated flight deals from Detroit to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 28 October 2025.
Fri 14/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 17/118:59 a.m.SFO - DTW
Nonstop4h 40mUnited Airlines
Deal found 26/10C$ 446
Mon 12/19:30 a.m.DTW - SFO
2 stops10h 25mSouthwest
Mon 19/17:50 a.m.SFO - DTW
2 stops9h 35mSouthwest
Deal found 27/10C$ 446
Sat 15/114:51 p.m.DTW - SFO
2 stops19h 04mAlaska Airlines
Tue 18/114:39 p.m.SFO - DTW
1 stop20h 16mAlaska Airlines
Deal found 26/10C$ 533
Tue 25/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Fri 28/117:00 a.m.SFO - DTW
1 stop6h 45mUnited Airlines
Deal found 27/10C$ 470
Sun 23/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 1/1211:50 p.m.SFO - DTW
1 stop7h 05mUnited Airlines
Deal found 27/10C$ 492
Mon 15/128:00 a.m.DTW - SFO
2 stops9h 25mSouthwest
Thu 25/128:20 a.m.SFO - DTW
2 stops10h 05mSouthwest
Deal found 26/10C$ 551
Fri 12/127:05 a.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Sun 4/19:25 p.m.SFO - DTW
Nonstop4h 41mUnited Airlines
Deal found 27/10C$ 544
Thu 22/17:10 a.m.DTW - SFO
Nonstop5h 21mUnited Airlines
Sun 25/14:10 p.m.SFO - DTW
Nonstop4h 38mUnited Airlines
Deal found 28/10C$ 544
Sat 24/17:10 a.m.DTW - SFO
Nonstop5h 21mUnited Airlines
Sat 31/11:40 p.m.SFO - DTW
Nonstop4h 34mUnited Airlines
Deal found 26/10C$ 544
Thu 4/127:05 a.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Sun 7/126:00 a.m.SFO - DTW
1 stop8h 07mUnited Airlines
Deal found 26/10C$ 558
Sat 22/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Thu 4/1211:55 p.m.SFO - DTW
1 stop8h 31mUnited Airlines
Deal found 25/10C$ 558
Direct flights from Detroit to San Francisco
Explore direct flight options from Detroit to San Francisco based on user searches, and compare prices and availability for your desired travel dates. Data last updated 28 October 2025.
Thu 27/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Wed 10/1211:25 a.m.SFO - DTW
Nonstop4h 39mUnited Airlines
Deal found 26/10C$ 427
Sat 8/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Sat 15/118:59 a.m.SFO - DTW
Nonstop4h 40mUnited Airlines
Deal found 25/10C$ 446
Fri 12/127:05 a.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 15/1211:25 a.m.SFO - DTW
Nonstop4h 39mUnited Airlines
Deal found 26/10C$ 481
Mon 8/127:05 a.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 5/19:25 p.m.SFO - DTW
Nonstop4h 41mUnited Airlines
Deal found 27/10C$ 544
Thu 20/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Thu 27/118:54 a.m.SFO - DTW
Nonstop4h 40mUnited Airlines
Deal found 28/10C$ 545
Tue 18/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Wed 3/1211:25 a.m.SFO - DTW
Nonstop4h 39mUnited Airlines
Deal found 27/10C$ 564
Sat 15/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Tue 18/118:59 a.m.SFO - DTW
Nonstop4h 40mUnited Airlines
Deal found 28/10C$ 586
Wed 24/127:10 a.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Thu 1/19:25 p.m.SFO - DTW
Nonstop4h 41mUnited Airlines
Deal found 25/10C$ 607
Tue 23/127:10 a.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Tue 30/129:25 p.m.SFO - DTW
Nonstop4h 41mUnited Airlines
Deal found 26/10C$ 611
Tue 23/127:10 a.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 29/129:25 p.m.SFO - DTW
Nonstop4h 41mUnited Airlines
Deal found 27/10C$ 615
Fri 5/127:05 a.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 8/1211:25 a.m.SFO - DTW
Nonstop4h 39mUnited Airlines
Deal found 28/10C$ 621
Last-minute flights from Detroit to San Francisco
Discover last-minute flight deals from Detroit to San Francisco. Data last updated 28 October 2025 and is based on user searches.
Fri 7/115:14 p.m.DTW - SFO
1 stop10h 00mMultiple Airlines
Sun 9/116:34 a.m.SFO - DTW
2 stops22h 09mMultiple Airlines
Deal found 27/10C$ 526
Sat 8/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Sat 15/118:59 a.m.SFO - DTW
Nonstop4h 40mUnited Airlines
Deal found 25/10C$ 446
Tue 11/118:00 a.m.DTW - SFO
1 stop9h 40mSouthwest
Fri 5/1210:50 a.m.SFO - DTW
1 stop6h 50mSouthwest
Deal found 26/10C$ 474
Wed 12/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Fri 9/111:56 p.m.SFO - DTW
1 stop7h 14mUnited Airlines
Deal found 25/10C$ 460
Wed 12/112:31 p.m.DTW - SFO
1 stop12h 28mJetBlue
Sun 16/119:10 p.m.SFO - DTW
1 stop10h 39mJetBlue
Deal found 28/10C$ 480
Thu 13/116:25 a.m.DTW - SFO
2 stops10h 25mSouthwest
Wed 19/115:25 a.m.SFO - DTW
2 stops9h 25mSouthwest
Deal found 26/10C$ 530
Sat 15/114:51 p.m.DTW - SFO
1 stop8h 19mAlaska Airlines
Tue 18/116:59 p.m.SFO - DTW
2 stops17h 56mAlaska Airlines
Deal found 28/10C$ 533
Thu 20/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 1/1211:50 p.m.SFO - DTW
1 stop7h 05mUnited Airlines
Deal found 27/10C$ 484
Mon 24/114:30 p.m.DTW - SFO
1 stop9h 25mUnited Airlines
Thu 4/1211:25 a.m.SFO - DTW
Nonstop4h 39mUnited Airlines
Deal found 28/10C$ 432
Tue 25/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Fri 28/117:00 a.m.SFO - DTW
1 stop6h 45mUnited Airlines
Deal found 27/10C$ 470
Tue 25/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Mon 1/1210:40 p.m.SFO - DTW
1 stop8h 15mUnited Airlines
Deal found 27/10C$ 492
Thu 27/115:35 p.m.DTW - SFO
Nonstop5h 25mUnited Airlines
Wed 10/1211:25 a.m.SFO - DTW
Nonstop4h 39mUnited Airlines
Deal found 26/10C$ 427
One-way flights from Detroit to San Francisco
Search for one-way flight options from Detroit to San Francisco. Find affordable one-way fares based on user searches. Data last updated 28 October 2025.
Fri 19/125:10 a.m.DTW - SFO
1 stop13h 50mSouthwest
Deal found 28/10C$ 224
Thu 1/110:49 a.m.DTW - SFO
2 stops38h 00mFrontier
Deal found 27/10C$ 227
Fri 19/1210:15 p.m.DTW - SFO
1 stop27h 39mSun Country Air
Deal found 27/10C$ 235
Wed 26/116:35 a.m.DTW - SFO
1 stop12h 30mSouthwest
Deal found 27/10C$ 243
Fri 14/114:51 p.m.DTW - SFO
1 stop9h 59mAlaska Airlines
Deal found 26/10C$ 257
Thu 25/126:10 a.m.DTW - SFO
1 stop7h 50mSouthwest
Deal found 26/10C$ 259
Sat 24/15:15 p.m.DTW - SFO
2 stops31h 40mAlaska Airlines
Deal found 26/10C$ 270
Tue 11/117:00 a.m.DTW - SFO
1 stop7h 00mSouthwest
Deal found 28/10C$ 273
Sun 9/116:45 p.m.DTW - SFO
1 stop25h 33mSun Country Air
Deal found 27/10C$ 277
Wed 7/15:15 p.m.DTW - SFO
2 stops28h 29mAlaska Airlines
Deal found 25/10C$ 283
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to San Francisco that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 28 October 2025.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.
Fly from
Detroit
Fly to
San Francisco
Route
Depart
Return
Price
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Fri 14/11
5:35 p.m.-8:00 p.m.
Nonstop5h 25m
San Francisco
Mon 17/11
8:59 a.m.-4:39 p.m.
Nonstop4h 40m
C$ 446
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Mon 12/1
9:30 a.m.-4:55 p.m.
2 stops10h 25m
San Francisco
Mon 19/1
7:50 a.m.-8:25 p.m.
2 stops9h 35m
C$ 446
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Tue 25/11
5:35 p.m.-8:00 p.m.
Nonstop5h 25m
San Francisco
Fri 28/11
7:00 a.m.-4:45 p.m.
1 stop6h 45m
C$ 470
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Sun 23/11
5:35 p.m.-8:00 p.m.
Nonstop5h 25m
San Francisco
Mon 1/12
11:50 p.m.-9:55 a.m.
1 stop7h 05m
C$ 492
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Sat 15/11
4:51 p.m.-8:55 a.m.
2 stops19h 04m
San Francisco
Tue 18/11
4:39 p.m.-3:55 p.m.
1 stop20h 16m
C$ 533
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Fri 12/12
7:05 a.m.-9:30 a.m.
Nonstop5h 25m
San Francisco
Sun 4/1
9:25 p.m.-5:06 a.m.
Nonstop4h 41m
C$ 544
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Thu 22/1
7:10 a.m.-9:31 a.m.
Nonstop5h 21m
San Francisco
Sun 25/1
4:10 p.m.-11:48 p.m.
Nonstop4h 38m
C$ 544
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Sat 24/1
7:10 a.m.-9:31 a.m.
Nonstop5h 21m
San Francisco
Sat 31/1
1:40 p.m.-9:14 p.m.
Nonstop4h 34m
C$ 544
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Mon 15/12
8:00 a.m.-2:25 p.m.
2 stops9h 25m
San Francisco
Thu 25/12
8:20 a.m.-9:25 p.m.
2 stops10h 05m
C$ 551
DetroitSan Francisco
DTW - SFO
DTWSFO
Detroit Metropolitan Wayne County
Thu 4/12
7:05 a.m.-9:30 a.m.
Nonstop5h 25m
San Francisco
Sun 7/12
6:00 a.m.-5:07 p.m.
1 stop8h 07m
C$ 558
Flights are sorted by cheapest round-trip flights first.
Deals found on 26/10
Showing 1-10 of 21 results
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Best time to book a flight from Detroit to San Francisco
Have a flexible travel schedule? Discover the best time to fly to San Francisco from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to San Francisco
Prices
More
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?
Use this chart to determine the optimal time to book a round-trip flight from Detroit to San Francisco. Price data was last updated on 24 October 2025.
The best time to book flights from Detroit Metropolitan Wayne County Airport to San Francisco is 79 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?
Currently, March is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Francisco (average of C$ 182). Flying from Detroit Metropolitan Wayne County Airport to San Francisco in August is currently the most expensive (average of C$ 358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to SFO?
Find hourly flight availability from Detroit to San Francisco. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 28 October 2025.
A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to San Francisco at noon. If you’re flexible enough to do this you can expect to save up to 37% on your trip compared to booking a flight in the evening.
What’s the top layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?
Share of one-stop round-trip flights from Detroit Metropolitan Wayne County Airport to San Francisco chosen by Cheapflights users in the past 12 months, using the same layover each way.
Minneapolis (MSP) – chosen by Cheapflights users on 29% of one-stop itineraries from Detroit Metropolitan Wayne County Airport to San Francisco on Cheapflights.
What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to San Francisco?
Shortest average travel time for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to San Francisco, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 7h 48m.
What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to San Francisco?
Shortest average travel time for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to San Francisco, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.
Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 7h 48m.
Which airport typically offers the quickest layover for flights from Detroit Metropolitan Wayne County Airport to San Francisco?
Average layover duration for 1-stop one-way flights from Detroit Metropolitan Wayne County Airport to San Francisco, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.
Flights via Seattle (SEA) offer the fastest connection on this route, with an average layover time of 1h 17m.
Reviews of airlines servicing San Francisco
Get insights into the airlines that provide service to San Francisco. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Francisco. Reviews last updated 28 October 2025.
Check out reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Detroit Metropolitan Wayne County Airport to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Related info for your journey
Find useful and relevant information for your journey from Detroit to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
What airports do I use to fly from Detroit to San Francisco?
To fly from Detroit to San Francisco, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to San Francisco (SFO). Nonstop flights to San Francisco from Detroit Metropolitan Wayne County take 5h 08m on average. When it comes time to book airfare, you have a few options: there are 9 outbound flights from Detroit Metropolitan Wayne County to San Francisco offered by 4 different airlines.
How long is the flight from Detroit Metropolitan Wayne County Airport to San Francisco?
There are many flights that can get you from Detroit Metropolitan Wayne County Airport to San Francisco in 5h 25m. Fly via United Airlines, Southwest, or Alaska Airlines to get the fastest option. Detroit Metropolitan Wayne County Airport and San Francisco are separated by a distance of 3335 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco round-trip?
Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to San Francisco round-trip from C$ 211. Other airlines that can offer you cheap pricing are Delta, from C$ 296, and Southwest, from C$ 431. These flights start at 70% lower than the current average price 3 months from now.
What are the cheapest airlines to fly from Detroit Metropolitan Wayne County Airport to San Francisco one-way?
For one-way options, check prices for Southwest. According to our data, you can fly for as low as C$ 224. Users have also found prices from C$ 235 and C$ 257 on Sun Country Air and Alaska Airlines, respectively.
What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to San Francisco?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to San Francisco on time: ITA Airways (94%), Air France (93%), Korean Air (92%).
What are the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco?
Looking at all options, your cheapest flight can be booked for C$ 452. While the most popular route (Detroit Metropolitan Wayne County - San Francisco) can be booked for C$ 243 on average, our data indicates C$ 703 when flying from Detroit Metropolitan Wayne County Airport to San Francisco.
Can I find deals for business class flights from Detroit to San Francisco?
Yes. Cheapflights offers flight deals from Detroit to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?
Currently, March is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Francisco (average of C$ 182). Flying from Detroit Metropolitan Wayne County Airport to San Francisco in August is currently the most expensive (average of C$ 358). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Explore flights to San Francisco departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 28 October 2025.
Top 4 airlines flying from Detroit to San Francisco
Discover the top 4 airlines that operate flights from Detroit to San Francisco. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 28 October 2025.
Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.
How does Cheapflights help users find flights from Detroit to San Francisco?
900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to San Francisco from Detroit today with Cheapflights!
Why should you use Cheapflights to find cheap flight tickets from Detroit to San Francisco?
It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Detroit to San Francisco.
Can Cheapflights find flights from Detroit to San Francisco with no change fees?
Certainly. Search results for flights to San Francisco from Detroit shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.
Can Cheapflights notify me if prices for flights from Detroit to San Francisco become cheaper?
Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!
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