What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to San Francisco?

Flights via Minneapolis (MSP) have the shortest average one-way travel time for 1-stop routes: 6h 44m.

What’s the cheapest layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Atlanta (ATL) is the most affordable 1-stop option, with an average round-trip price of C$ 322.

What’s the top layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Chicago (ORD) – chosen by Cheapflights users on 45% of one-stop itineraries from Detroit Metropolitan Wayne County Airport to San Francisco on Cheapflights.

Which airport typically offers the quickest layover for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Flights via Charlotte (CLT) offer the fastest connection on this route, with an average layover time of 0h 49m.

Weekly flight availability from Detroit Metropolitan Wayne County Airport to San Francisco

The most flights from DTW to SFO are scheduled on a Monday (13 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (7 on average).

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 112.0 mm per month. January is typically the wettest month, when rainfall can reach 112.0 mm. July is typically the driest time to visit San Francisco when rainfall is around 0.0 mm.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 17.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 11.0 C).

What are the most popular airlines that fly from Detroit Metropolitan Wayne County Airport to San Francisco?

When booking a flight from Detroit Metropolitan Wayne County Airport to San Francisco, you may want to consider flying on United Airlines, Delta or Frontier as they are the most popular for this route.

What airports do I use to fly from Detroit to San Francisco?

To fly from Detroit to San Francisco, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to San Francisco (SFO). Nonstop flights to San Francisco from Detroit Metropolitan Wayne County take 4h 56m on average. When it comes time to book airfare, you have a few options: there are 11 outbound flights from Detroit Metropolitan Wayne County to San Francisco offered by 5 different airlines.

Can I find deals for flights from Detroit to San Francisco that include hotel bookings?

Yes. In addition to deals on Detroit to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Detroit to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to San Francisco.

Can I find deals for business class flights from Detroit to San Francisco?

Yes. Cheapflights offers flight deals from Detroit to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 153+ Cheap Flights from Detroit Metropolitan Wayne County Airport to San Francisco

Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to San Francisco are usually found in July or January, booked 62 days in advance, depart on a Wednesday or Thursday and return on a Monday

Cheap flight deals from Detroit to San Francisco

Enter your travel dates to find the best prices.

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One-way

Cheapest flights from Detroit to San Francisco
Explore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 March 2026.

Wed 19/85:40 p.m.

DTW

SFO

1 stop8h 24m

Frontier

Sat 22/86:00 a.m.

SFO

DTW

1 stop11h 59m

Frontier

Deal found 7/3C$ 396

Wed 25/39:02 a.m.

DTW

SFO

1 stop13h 12m

Frontier

Wed 1/44:01 p.m.

SFO

DTW

1 stop11h 59m

Frontier

Deal found 7/3C$ 403

Tue 24/39:02 a.m.

DTW

SFO

1 stop13h 12m

Frontier

Fri 3/49:00 p.m.

SFO

DTW

1 stop10h 58m

Frontier

Deal found 8/3C$ 406

Thu 2/411:54 a.m.

DTW

SFO

1 stop15h 29m

Frontier

Mon 6/410:50 p.m.

SFO

DTW

2 stops55h 49m

Frontier

Deal found 5/3C$ 407

Tue 10/39:02 a.m.

DTW

SFO

1 stop13h 12m

Frontier

Tue 17/39:04 p.m.

SFO

DTW

1 stop10h 55m

Frontier

Deal found 8/3C$ 411

Mon 16/39:02 a.m.

DTW

SFO

1 stop13h 12m

Frontier

Wed 18/36:00 a.m.

SFO

DTW

1 stop25h 59m

Frontier

Deal found 8/3C$ 413

Tue 31/36:05 a.m.

DTW

SFO

2 stops15h 32m

Multiple Airlines

Wed 1/44:01 p.m.

SFO

DTW

1 stop11h 59m

Multiple Airlines

Deal found 7/3C$ 414

Fri 3/47:10 a.m.

DTW

SFO

Nonstop5h 20m

United Airlines

Sat 25/41:30 p.m.

SFO

DTW

Nonstop4h 55m

United Airlines

Deal found 8/3C$ 419

Wed 25/39:02 a.m.

DTW

SFO

1 stop13h 12m

Frontier

Mon 30/38:14 p.m.

SFO

DTW

2 stops26h 11m

Frontier

Deal found 8/3C$ 421

Mon 30/39:02 a.m.

DTW

SFO

1 stop13h 17m

Frontier

Mon 30/310:38 p.m.

SFO

DTW

1 stop14h 39m

Frontier

Deal found 8/3C$ 425

Tue 10/311:54 a.m.

DTW

SFO

1 stop15h 34m

Frontier

Wed 18/36:00 a.m.

SFO

DTW

1 stop25h 59m

Frontier

Deal found 9/3C$ 427

Find flight deals from Detroit to San Francisco

Round-trip from	C$ 396
One-way from	C$ 153
Popular in	March
Cheapest in	July
Average price	C$ 704
Good round-trip deal	C$ 609 or less

Frontier
19/8-22/8
2 total stops
20h 23m total
Detroit to San Francisco

Search Deals

Frontier
21/4
2 total stops
31h 21m total
Detroit to San Francisco

Search Deals

Highest demand for flights based on searches. 3% potential increase in price (C$ 25 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease (C$ 16 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in March 2026

Search Deals

Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to San Francisco.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sat 18/4

4:55 p.m.-10:27 p.m.

1 stop8h 32m

San Francisco

Sat 25/4

2:00 p.m.-5:44 a.m.

1 stop12h 44m

C$ 446

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Tue 7/4

1:40 p.m.-10:05 p.m.

2 stops11h 25m

San Francisco

Wed 8/4

11:25 a.m.-11:05 p.m.

2 stops8h 40m

C$ 493

Quickest round-trip

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Tue 7/4

8:22 p.m.-10:36 p.m.

Nonstop5h 14m

San Francisco

Mon 13/4

10:55 p.m.-6:30 a.m.

Nonstop4h 35m

C$ 541

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sat 18/4

7:10 a.m.-9:30 a.m.

Nonstop5h 20m

San Francisco

Sat 25/4

1:30 p.m.-9:25 p.m.

Nonstop4h 55m

C$ 556

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Fri 26/6

8:30 p.m.-12:10 a.m.

1 stop6h 40m

San Francisco

Wed 1/7

10:30 a.m.-12:05 a.m.

2 stops10h 35m

C$ 562

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Sun 5/4

7:10 a.m.-9:30 a.m.

Nonstop5h 20m

San Francisco

Fri 24/4

12:35 p.m.-11:59 p.m.

1 stop8h 24m

C$ 569

Cheapest one-way

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Fri 3/4

6:40 p.m.-12:50 a.m.

2 stops9h 10m

C$ 231

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Mon 20/4

8:40 a.m.-3:25 p.m.

2 stops9h 45m

C$ 285

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Tue 28/4

7:10 a.m.-9:30 a.m.

Nonstop5h 20m

C$ 297

DetroitSan Francisco

DTW - SFO

DTWSFO

Detroit Metropolitan Wayne County

Mon 6/4

7:10 a.m.-9:30 a.m.

Nonstop5h 20m

C$ 297

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/3

Showing 1-10 of 18 resultsSorted by cheapest first

Best time to book a flight from Detroit to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Detroit with our price prediction graph.

DTW-SFO

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to San Francisco

Prices

Airlines

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

The best time to book flights from Detroit Metropolitan Wayne County Airport to San Francisco is 62 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

Currently, September is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Francisco (average of C$ 213). Flying from Detroit Metropolitan Wayne County Airport to San Francisco in November is currently the most expensive (average of C$ 402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to SFO?

A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to San Francisco in the morning. If you’re flexible enough to do this you can expect to save up to 40% on your trip compared to booking a flight in the evening.

Reviews of airlines servicing San Francisco

Check out reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Detroit Metropolitan Wayne County Airport to San Francisco to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,317 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,317 reviews

Southwest

8.0

Very good

4,317 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

7.9

Good

8,276 reviews

Southwest

8.0

Very good

4,317 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

9,409 reviews

Southwest

8.0

Very good

4,317 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.1

Good

11,414 reviews

Southwest

8.0

Very good

4,317 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.7

Fair

3,033 reviews

Southwest

8.0

Very good

4,317 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

What airports do I use to fly from Detroit to San Francisco?
To fly from Detroit to San Francisco, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to San Francisco (SFO). Nonstop flights to San Francisco from Detroit Metropolitan Wayne County take 4h 56m on average. When it comes time to book airfare, you have a few options: there are 11 outbound flights from Detroit Metropolitan Wayne County to San Francisco offered by 5 different airlines.
How long is the flight from Detroit Metropolitan Wayne County Airport to San Francisco?
There are many flights that can get you from Detroit Metropolitan Wayne County Airport to San Francisco in 8h 32m. Fly via Alaska Airlines or Southwest to get the fastest option. Detroit Metropolitan Wayne County Airport and San Francisco are separated by a distance of 3335 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.
What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco round-trip?
Cheapflights users have booked flights from Detroit Metropolitan Wayne County Airport to San Francisco round-trip from C$ 217. Other airlines that can offer you cheap pricing are Delta, from C$ 287, and United Airlines, from C$ 379. These flights start at 63% lower than the current average price 3 months from now.
What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to San Francisco?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to San Francisco on time: Virgin Atlantic (66%), Asiana Airlines (64%), Air New Zealand (64%).
What are the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco?
Looking at all options, your cheapest flight can be booked for C$ 560. While the most popular route (Detroit Metropolitan Wayne County - San Francisco) can be booked for C$ 361 on average, our data indicates C$ 1,776 when flying from Detroit Metropolitan Wayne County Airport to San Francisco.
Can I find deals for flights from Detroit to San Francisco that include hotel bookings?
Yes. In addition to deals on Detroit to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Detroit to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to San Francisco.
Can I find deals for business class flights from Detroit to San Francisco?
Yes. Cheapflights offers flight deals from Detroit to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?
Currently, September is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to San Francisco (average of C$ 213). Flying from Detroit Metropolitan Wayne County Airport to San Francisco in November is currently the most expensive (average of C$ 402). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Detroit to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Frontier	CheapestC$ 217	AverageC$ 368	FlexibilityNo cancel fee	On-time62%	Search Frontier flights
Delta	CheapestC$ 287	AverageC$ 472	FlexibilityNo cancel fee	On-timeN/A	Search Delta flights
United Airlines	CheapestC$ 379	AverageC$ 630	FlexibilityNo cancel fee	On-time69%	Search United Airlines flights
American Airlines	CheapestC$ 396	AverageC$ 474	FlexibilityNo cancel fee	On-time71%	Search American Airlines flights
Southwest	CheapestC$ 418	AverageC$ 506	FlexibilityNo cancel fee	On-time63%	Search Southwest flights

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How does Cheapflights help users find flights from Detroit to San Francisco?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to San Francisco from Detroit today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Detroit to San Francisco?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Detroit to San Francisco.

Can Cheapflights find flights from Detroit to San Francisco with no change fees?

Certainly. Search results for flights to San Francisco from Detroit shown to you on Cheapflights can be narrowed down with different useful search filters, which includes flexible booking options.

Can Cheapflights notify me if prices for flights from Detroit to San Francisco become cheaper?

Yes, and it’s super simple to set up. Click the bell icon next to the flight deals above and provide a valid email address to enable Price Alerts. That’s it!

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Cheap flights from Detroit Metropolitan Wayne County Airport to San Francisco from C$ 153

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/4. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Detroit to San Francisco

Cheapest flights from Detroit to San FranciscoExplore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 March 2026.

Explore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 March 2026.

Best flights from Detroit to San FranciscoDiscover carefully curated flight deals from Detroit to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 10 March 2026.

Discover carefully curated flight deals from Detroit to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 10 March 2026.

Direct flights from Detroit to San FranciscoExplore direct flight options from Detroit to San Francisco based on user searches, and compare prices and availability for your desired travel dates. Data last updated 10 March 2026.

Explore direct flight options from Detroit to San Francisco based on user searches, and compare prices and availability for your desired travel dates. Data last updated 10 March 2026.

Last-minute flights from Detroit to San FranciscoDiscover last-minute flight deals from Detroit to San Francisco. Data last updated 10 March 2026 and is based on user searches.

Discover last-minute flight deals from Detroit to San Francisco. Data last updated 10 March 2026 and is based on user searches.

One-way flights from Detroit to San FranciscoSearch for one-way flight options from Detroit to San Francisco. Find affordable one-way fares based on user searches. Data last updated 10 March 2026.

Search for one-way flight options from Detroit to San Francisco. Find affordable one-way fares based on user searches. Data last updated 10 March 2026.

Find flight deals from Detroit to San Francisco

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to San Francisco that are best for you.

Best time to book a flight from Detroit to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Detroit with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to San Francisco

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

What is the cheapest time of day to fly from DTW to SFO?

Weekly flight availability from Detroit Metropolitan Wayne County Airport to San Francisco

What’s the top layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

What’s the cheapest layover airport for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

What’s the fastest layover option from Detroit Metropolitan Wayne County Airport to San Francisco?

Which airport typically offers the quickest layover for flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Reviews of airlines servicing San Francisco

Related info for your journey

Find useful and relevant information for your journey from Detroit to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airports do I use to fly from Detroit to San Francisco?

How long is the flight from Detroit Metropolitan Wayne County Airport to San Francisco?

What are the cheapest airlines flying from Detroit Metropolitan Wayne County Airport to San Francisco round-trip?

What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to San Francisco?

What are the cheapest flights from Detroit Metropolitan Wayne County Airport to San Francisco?

Can I find deals for flights from Detroit to San Francisco that include hotel bookings?

How can I find direct flights from Detroit to San Francisco?

Can I find deals for business class flights from Detroit to San Francisco?

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to San Francisco?

Travelling to a place near San Francisco?

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Alternative routes for Detroit to San Francisco

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Complete your trip

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Direct flights to California

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Search flights from Detroit to San Francisco by cabin class

Find flights from Detroit to San Francisco, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Detroit and San Francisco flights

Browse other Detroit and San Francisco flight options. Last updated on 10 March 2026.

Other flights from Detroit

Browse through other flights departing from Detroit. Flights are based on user searches made on Cheapflights and were last updated on 10 March 2026.

Popular flight searches

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Other flights to San Francisco

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Top 5 airlines flying from Detroit to San Francisco

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Can Cheapflights find flights from Detroit to San Francisco with no change fees?

Can Cheapflights notify me if prices for flights from Detroit to San Francisco become cheaper?

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Cheapest flights from Detroit to San Francisco
Explore the most affordable flight options available from Detroit to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 March 2026.

Best flights from Detroit to San Francisco
Discover carefully curated flight deals from Detroit to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 10 March 2026.

Direct flights from Detroit to San Francisco
Explore direct flight options from Detroit to San Francisco based on user searches, and compare prices and availability for your desired travel dates. Data last updated 10 March 2026.

Last-minute flights from Detroit to San Francisco
Discover last-minute flight deals from Detroit to San Francisco. Data last updated 10 March 2026 and is based on user searches.

One-way flights from Detroit to San Francisco
Search for one-way flight options from Detroit to San Francisco. Find affordable one-way fares based on user searches. Data last updated 10 March 2026.