What’s the top layover airport for flights from Buffalo to San Francisco?

Denver (DEN) – chosen by Cheapflights users on 30% of one-stop itineraries from Buffalo to San Francisco on Cheapflights.

What’s the fastest layover option from Buffalo to San Francisco?

Flights via Chicago (MDW) have the shortest average one-way travel time for 1-stop routes: 7h 45m.

Which airport typically offers the quickest layover for flights from Buffalo to San Francisco?

Flights via Chicago (MDW) offer the fastest connection on this route, with an average layover time of 1h 10m.

What’s the cheapest layover airport for flights from Buffalo to San Francisco?

Atlanta (ATL) is the most affordable 1-stop option, with an average round-trip price of C$ 382.

How long is the flight from Buffalo to San Francisco?

Frontier can get you from Buffalo to San Francisco in just under 12h 04m. Your travel time can differ by up to . Airlines will cover a distance of 3705 km.

What are the cheapest airlines flying from Buffalo to San Francisco round-trip?

Delta, at C$ 192, was found to be the cheapest airline from Buffalo to San Francisco.Alternate airlines to your destination round-trip include Frontier and Southwest. Users have found that Delta is 60% cheaper than the other options available to this destination.

What are the cheapest airlines to fly from Buffalo to San Francisco one-way?

One-way options have recently been found by users for as low as C$ 166 on Frontier. Other airlines that offer cheap prices include Southwest from C$ 181 and Delta from C$ 192 one-way.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 112.0 mm per month. January is typically the wettest month, when rainfall can reach 112.0 mm. July is typically the driest time to visit San Francisco when rainfall is around 0.0 mm.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 17.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 11.0 C).

What are the most popular airlines that fly from Buffalo to San Francisco?

American Airlines, JetBlue and Delta are the most popular airlines when flying from Buffalo to San Francisco.

What is the cheapest day to fly round-trip from Buffalo to San Francisco?

Users have found that leaving on a Tuesday can be a cost-effective option. It’s possible to save up to 49% on your flight compared to booking on days when demand is much higher.

How far in advance should I book a flight from Buffalo to San Francisco?

Find a great deal and save up to 202% by booking at least 57 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Buffalo to San Francisco within the next two weeks, with the cheapest ticket starting at C$ 493.

What is the cheapest month to fly from Buffalo to San Francisco?

Our data shows that August tends to be the cheapest month to fly to San Francisco from Buffalo. Users have commonly found prices around C$ 489 for the month, but tickets can be as low as C$ 232. Due to multiple factors, prepare for potentially higher prices in December.

Can I find deals for flights from Buffalo to San Francisco that include hotel bookings?

Yes. In addition to deals on Buffalo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Buffalo to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to San Francisco.

Can I find deals for business class flights from Buffalo to San Francisco?

Yes. Cheapflights offers flight deals from Buffalo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 166+ Cheap Flights from Buffalo to San Francisco

Cheapflights Tip: The best prices from Buffalo to San Francisco are usually found in August or January, booked 56 days in advance, depart on a Wednesday or Saturday and return on a Monday

Cheap flight deals from Buffalo to San Francisco

Round-trip from	C$ 218
One-way from	C$ 166
Popular in	December
Cheapest in	August
Average price	C$ 503

Frontier
3/10-5/10
2 total stops
16h 52m total
Buffalo to San Francisco

Search Deals

Frontier
2/10
1 total stop
12h 04m total
Buffalo to San Francisco

Search Deals

High demand for flights, 0% potential price rise

Search Deals

Cheapest flight prices on average. 1% potential price decrease (C$ 9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2025

Search Deals

Find flight deals from Buffalo to San Francisco

Cheapest flights from Buffalo to San Francisco
Explore the most affordable flight options available from Buffalo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Fri 3/104:57 p.m.BUF - SFO

1 stop10h 19mFrontier

Sun 5/106:29 a.m.SFO - BUF

1 stop6h 33mFrontier

Deal found 15/9C$ 218

Thu 2/1012:17 p.m.BUF - SFO

1 stop12h 04mFrontier

Sun 5/106:29 a.m.SFO - BUF

1 stop6h 33mFrontier

Deal found 15/9C$ 224

Fri 3/104:57 p.m.BUF - SFO

1 stop10h 19mFrontier

Mon 6/106:29 a.m.SFO - BUF

1 stop6h 34mFrontier

Deal found 13/9C$ 246

Thu 2/1012:17 p.m.BUF - SFO

1 stop12h 04mFrontier

Mon 6/106:29 a.m.SFO - BUF

1 stop6h 34mFrontier

Deal found 13/9C$ 290

Sat 18/101:02 p.m.BUF - SFO

1 stop11h 21mFrontier

Mon 27/106:34 a.m.SFO - BUF

1 stop6h 55mFrontier

Deal found 13/9C$ 298

Fri 17/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Sun 26/108:21 p.m.SFO - BUF

1 stop17h 08mFrontier

Deal found 13/9C$ 320

Fri 17/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Mon 20/106:34 a.m.SFO - BUF

1 stop6h 55mFrontier

Deal found 14/9C$ 322

Fri 10/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Sun 19/108:21 p.m.SFO - BUF

1 stop17h 08mFrontier

Deal found 14/9C$ 332

Sat 18/101:02 p.m.BUF - SFO

1 stop11h 21mFrontier

Sat 25/1010:23 p.m.SFO - BUF

1 stop9h 56mFrontier

Deal found 13/9C$ 350

Thu 20/118:05 a.m.BUF - SFO

1 stop8h 15mSouthwest

Mon 24/115:15 a.m.SFO - BUF

1 stop11h 05mSouthwest

Deal found 14/9C$ 365

Best flights from Buffalo to San Francisco
Discover carefully curated flight deals from Buffalo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 15 September 2025.

Thu 2/1012:17 p.m.BUF - SFO

1 stop12h 04mFrontier

Sun 5/106:29 a.m.SFO - BUF

1 stop6h 33mFrontier

Deal found 15/9C$ 224

Thu 20/118:05 a.m.BUF - SFO

1 stop8h 15mSouthwest

Mon 24/115:15 a.m.SFO - BUF

1 stop11h 05mSouthwest

Deal found 14/9C$ 365

Wed 15/105:31 p.m.BUF - SFO

1 stop10h 28mJetBlue

Mon 20/109:00 p.m.SFO - BUF

1 stop8h 59mJetBlue

Deal found 13/9C$ 399

Fri 3/104:57 p.m.BUF - SFO

1 stop10h 19mFrontier

Sun 5/106:29 a.m.SFO - BUF

1 stop6h 33mFrontier

Deal found 13/9C$ 246

Fri 17/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Mon 20/106:34 a.m.SFO - BUF

1 stop6h 55mFrontier

Deal found 13/9C$ 320

Fri 17/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Mon 27/106:34 a.m.SFO - BUF

1 stop6h 55mFrontier

Deal found 13/9C$ 320

Tue 24/212:45 p.m.BUF - SFO

1 stop13h 04mJetBlue

Thu 26/29:35 p.m.SFO - BUF

1 stop7h 54mJetBlue

Deal found 14/9C$ 399

Mon 15/126:15 a.m.BUF - SFO

1 stop7h 45mSouthwest

Mon 26/19:30 p.m.SFO - BUF

1 stop7h 35mSouthwest

Deal found 13/9C$ 399

Thu 11/128:05 a.m.BUF - SFO

1 stop8h 15mSouthwest

Mon 15/1210:35 a.m.SFO - BUF

1 stop7h 30mSouthwest

Deal found 13/9C$ 399

Fri 9/15:50 a.m.BUF - SFO

1 stop10h 35mSouthwest

Mon 12/19:30 p.m.SFO - BUF

1 stop7h 35mSouthwest

Deal found 15/9C$ 399

Last-minute flights from Buffalo to San Francisco
Discover last-minute flight deals from Buffalo to San Francisco. Data last updated 15 September 2025 and is based on user searches.

Thu 2/1012:17 p.m.BUF - SFO

1 stop12h 04mFrontier

Sun 5/106:29 a.m.SFO - BUF

1 stop6h 33mFrontier

Deal found 15/9C$ 224

Fri 3/104:57 p.m.BUF - SFO

1 stop10h 19mFrontier

Sun 5/106:29 a.m.SFO - BUF

1 stop6h 33mFrontier

Deal found 15/9C$ 218

Fri 10/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Sun 19/108:21 p.m.SFO - BUF

1 stop17h 08mFrontier

Deal found 14/9C$ 332

Fri 17/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Sun 26/108:21 p.m.SFO - BUF

1 stop17h 08mFrontier

Deal found 13/9C$ 320

Fri 17/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Mon 20/106:34 a.m.SFO - BUF

1 stop6h 55mFrontier

Deal found 14/9C$ 322

Fri 17/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Sat 25/1010:23 p.m.SFO - BUF

1 stop9h 56mFrontier

Deal found 13/9C$ 372

Sat 18/101:02 p.m.BUF - SFO

1 stop11h 21mFrontier

Mon 27/106:34 a.m.SFO - BUF

1 stop6h 55mFrontier

Deal found 13/9C$ 298

Sat 18/101:02 p.m.BUF - SFO

1 stop11h 21mFrontier

Sat 25/1010:23 p.m.SFO - BUF

1 stop9h 56mFrontier

Deal found 13/9C$ 350

One-way flights from Buffalo to San Francisco
Search for one-way flight options from Buffalo to San Francisco. Find affordable one-way fares based on user searches. Data last updated 15 September 2025.

Thu 2/1012:17 p.m.BUF - SFO

1 stop12h 04mFrontier

Deal found 15/9C$ 166

Wed 26/113:20 p.m.BUF - SFO

1 stop11h 35mSouthwest

Deal found 14/9C$ 181

Wed 29/1012:49 p.m.BUF - SFO

1 stop8h 02mDelta

Deal found 15/9C$ 192

Wed 29/105:30 p.m.BUF - SFO

1 stop9h 29mJetBlue

Deal found 14/9C$ 200

Mon 9/312:05 p.m.BUF - SFO

2 stops11h 00mSouthwest

Deal found 13/9C$ 207

Thu 30/109:04 p.m.BUF - SFO

2 stops30h 10mFrontier

Deal found 15/9C$ 221

Wed 29/101:05 p.m.BUF - SFO

2 stops11h 05mSouthwest

Deal found 13/9C$ 222

Sat 27/97:11 p.m.BUF - SFO

2 stops42h 32mFrontier

Deal found 13/9C$ 235

Thu 11/127:09 p.m.BUF - SFO

2 stops52h 59mFrontier

Deal found 12/9C$ 238

Fri 17/105:24 p.m.BUF - SFO

1 stop9h 50mFrontier

Deal found 14/9C$ 239

Sun 16/117:00 a.m.BUF - SFO

1 stop9h 07mJetBlue

Deal found 15/9C$ 254

Tue 21/107:10 a.m.BUF - SFO

2 stops10h 50mSouthwest

Deal found 13/9C$ 269

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Thu 2/10

12:17 p.m.-9:21 p.m.

1 stop12h 04m

San Francisco

Sun 5/10

6:29 a.m.-4:02 p.m.

1 stop6h 33m

C$ 224

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Fri 3/10

4:57 p.m.-12:16 a.m.

1 stop10h 19m

San Francisco

Sun 5/10

6:29 a.m.-4:02 p.m.

1 stop6h 33m

C$ 246

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Fri 17/10

5:24 p.m.-12:14 a.m.

1 stop9h 50m

San Francisco

Mon 20/10

6:34 a.m.-4:29 p.m.

1 stop6h 55m

C$ 320

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Fri 17/10

5:24 p.m.-12:14 a.m.

1 stop9h 50m

San Francisco

Mon 27/10

6:34 a.m.-4:29 p.m.

1 stop6h 55m

C$ 320

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Thu 20/11

8:05 a.m.-1:20 p.m.

1 stop8h 15m

San Francisco

Mon 24/11

5:15 a.m.-7:20 p.m.

1 stop11h 05m

C$ 365

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Wed 15/10

5:31 p.m.-12:59 a.m.

1 stop10h 28m

San Francisco

Mon 20/10

9:00 p.m.-8:59 a.m.

1 stop8h 59m

C$ 399

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Tue 24/2

12:45 p.m.-10:49 p.m.

1 stop13h 04m

San Francisco

Thu 26/2

9:35 p.m.-8:29 a.m.

1 stop7h 54m

C$ 399

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Mon 15/12

6:15 a.m.-11:00 a.m.

1 stop7h 45m

San Francisco

Mon 26/1

9:30 p.m.-8:05 a.m.

1 stop7h 35m

C$ 399

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Thu 11/12

8:05 a.m.-1:20 p.m.

1 stop8h 15m

San Francisco

Mon 15/12

10:35 a.m.-9:05 p.m.

1 stop7h 30m

C$ 399

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Fri 9/1

5:50 a.m.-1:25 p.m.

1 stop10h 35m

San Francisco

Mon 12/1

9:30 p.m.-8:05 a.m.

1 stop7h 35m

C$ 399

Flights are sorted by cheapest round-trip flights first.

Deals found on 15/9

Showing 1-10 of 20 results

Best time to book a flight from Buffalo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Buffalo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to San Francisco

Prices

How far ahead should I book a flight from Buffalo to San Francisco?

To ensure you get the cheapest price possible for a flight from Buffalo to San Francisco, you should look to book at least 56 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Buffalo to San Francisco?

Currently, January is the cheapest month in which you can book a flight from Buffalo to San Francisco (average of C$ 276). Flying from Buffalo to San Francisco in December is currently the most expensive (average of C$ 368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to SFO?

It’s typically best to fly out from Buffalo to San Francisco in the evening. Doing so could potentially save you 17% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Buffalo to San Francisco?

Travelers seeking maximum savings on their Buffalo to San Francisco flight should consider departing on Monday evenings when fares are most often at their lowest. Monday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Buffalo to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,242 reviews

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

8.0

Very good

7,954 reviews

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

8,929 reviews

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.8

Fair

3,172 reviews

Southwest

8.0

Very good

4,242 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

How long is the flight from Buffalo to San Francisco?
Frontier can get you from Buffalo to San Francisco in just under 12h 04m. Your travel time can differ by up to . Airlines will cover a distance of 3705 km.
What are the cheapest airlines flying from Buffalo to San Francisco round-trip?
Delta, at C$ 192, was found to be the cheapest airline from Buffalo to San Francisco.Alternate airlines to your destination round-trip include Frontier and Southwest. Users have found that Delta is 60% cheaper than the other options available to this destination.
What are the cheapest airlines to fly from Buffalo to San Francisco one-way?
One-way options have recently been found by users for as low as C$ 166 on Frontier. Other airlines that offer cheap prices include Southwest from C$ 181 and Delta from C$ 192 one-way.
Can I find deals for flights from Buffalo to San Francisco that include hotel bookings?
Yes. In addition to deals on Buffalo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Buffalo to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to San Francisco.
Can I find deals for business class flights from Buffalo to San Francisco?
Yes. Cheapflights offers flight deals from Buffalo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Buffalo to San Francisco?
Currently, January is the cheapest month in which you can book a flight from Buffalo to San Francisco (average of C$ 276). Flying from Buffalo to San Francisco in December is currently the most expensive (average of C$ 368). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Richmond

Newark

Alameda

Redwood City

Burlingame

San Bruno

South San Francisco

Scotts Valley

Belmont

Novato

Millbrae

Santa Clara

Vallejo

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Top 6 airlines flying from Buffalo to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Delta	CheapestC$ 192	AverageC$ 454	FlexibilityNo cancel fee	On-timeN/A	Search Delta flights
Frontier	CheapestC$ 203	AverageC$ 401	FlexibilityNo cancel fee	On-time62%	Search Frontier flights
Southwest	CheapestC$ 277	AverageC$ 510	FlexibilityNo cancel fee	On-time63%	Search Southwest flights
American Airlines	CheapestC$ 314	AverageC$ 384	FlexibilityNo cancel fee	On-time71%	Search American Airlines flights
JetBlue	CheapestC$ 356	AverageC$ 439	FlexibilityNo cancel fee	On-time62%	Search JetBlue flights
United Airlines	CheapestC$ 474	AverageC$ 733	FlexibilityNo cancel fee	On-time69%	Search United Airlines flights

Fly with Cheapflights

How does Cheapflights help users find flights from Buffalo to San Francisco?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to San Francisco from Buffalo today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Buffalo to San Francisco?

Cheapflights simply makes it quick and affordable to book flights from Buffalo to San Francisco by bringing together all flight options from hundreds of airlines and agencies online — and put it in one place for you to choose from. Plus, Cheapflights is 100% free to use for all.

Can Cheapflights find flights from Buffalo to San Francisco with no change fees?

Need flexible booking options for your flight to San Francisco from Buffalo? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Buffalo to San Francisco become cheaper?

Of course! You can now track prices for flights from Buffalo to San Francisco and get an alert from Cheapflights when they change. Have a valid email address ready and click the bell icon next to the flight deals above to set up your price alerts.

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Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

Cheap flights from Buffalo to San Francisco from C$ 166

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/10. Fares are subject to change and may not be available on all flights or dates of travel.

Cheapflights Tip: The best prices from Buffalo to San Francisco are usually found in August or January, booked 56 days in advance, depart on a Wednesday or Saturday and return on a Monday

Cheap flight deals from Buffalo to San Francisco

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Buffalo to San Francisco

Cheapest flights from Buffalo to San FranciscoExplore the most affordable flight options available from Buffalo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Explore the most affordable flight options available from Buffalo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to San Francisco that are best for you.

Best time to book a flight from Buffalo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Buffalo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to San Francisco

How far ahead should I book a flight from Buffalo to San Francisco?

What is the cheapest month to book a flight from Buffalo to San Francisco?

What is the cheapest time of day to fly from BUF to SFO?

What is the cheapest day to fly from Buffalo to San Francisco?

What’s the top layover airport for flights from Buffalo to San Francisco?

What’s the fastest layover option from Buffalo to San Francisco?

What’s the fastest layover option from Buffalo to San Francisco?

Which airport typically offers the quickest layover for flights from Buffalo to San Francisco?

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Buffalo to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Buffalo to San Francisco?

What are the cheapest airlines flying from Buffalo to San Francisco round-trip?

What are the cheapest airlines to fly from Buffalo to San Francisco one-way?

Can I find deals for flights from Buffalo to San Francisco that include hotel bookings?

How can I find direct flights from Buffalo to San Francisco?

Can I find deals for business class flights from Buffalo to San Francisco?

What is the cheapest month to book a flight from Buffalo to San Francisco?

Travelling to a place near San Francisco?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Buffalo to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 6 airlines flying from Buffalo to San Francisco

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How does Cheapflights help users find flights from Buffalo to San Francisco?

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Can Cheapflights find flights from Buffalo to San Francisco with no change fees?

Can Cheapflights notify me if prices for flights from Buffalo to San Francisco become cheaper?

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Cheapest flights from Buffalo to San Francisco
Explore the most affordable flight options available from Buffalo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 15 September 2025.