What’s the cheapest layover airport for flights from Buffalo to San Francisco?

Atlanta (ATL) is the most affordable 1-stop option, with an average round-trip price of C$ 321.

What’s the fastest layover option from Buffalo to San Francisco?

Flights via Chicago (ORD) have the shortest average one-way travel time for 1-stop routes: 7h 35m.

Which airport typically offers the quickest layover for flights from Buffalo to San Francisco?

Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 05m.

What’s the top layover airport for flights from Buffalo to San Francisco?

Atlanta (ATL) – chosen by Cheapflights users on 27% of one-stop itineraries from Buffalo to San Francisco on Cheapflights.

How long is the flight from Buffalo to San Francisco?

Frontier, United Airlines, and Delta can get you from Buffalo to San Francisco in just under 9h 07m. Your travel time can differ by up to 2h 03m. Airlines will cover a distance of 3705 km. This flight may include one or multiple stops.

What are the cheapest airlines flying from Buffalo to San Francisco round-trip?

Frontier, at C$ 154, was found to be the cheapest airline from Buffalo to San Francisco.Alternate airlines to your destination round-trip include United Airlines and Delta. Users have found that Frontier is 67% cheaper than the other options available to this destination.

In terms of precipitation, rainfall in San Francisco ranges from 0.0 - 112.0 mm per month. January is typically the wettest month, when rainfall can reach 112.0 mm. July is typically the driest time to visit San Francisco when rainfall is around 0.0 mm.

If weather is an important factor for your trip to San Francisco, use this chart to help with planning. For those seeking warmer temperatures, September is the ideal time of year to visit, when temperatures reach an average of 17.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 11.0 C).

What are the most popular airlines that fly from Buffalo to San Francisco?

Southwest, Frontier and American Airlines are the most popular airlines when flying from Buffalo to San Francisco.

What is the cheapest time of day to fly from BUF to SFO?

When flying from Buffalo to San Francisco, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Can I find deals for flights from Buffalo to San Francisco that include hotel bookings?

Yes. In addition to deals on Buffalo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Buffalo to San Francisco?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to San Francisco.

Can I find deals for business class flights from Buffalo to San Francisco?

Yes. Cheapflights offers flight deals from Buffalo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 182+ Flights from Buffalo to San Francisco

Q: How much does it cost to fly round-trip from Buffalo to San Francisco?

Airfare is typical for this route at the moment. Buffalo to San Francisco flights typically cost between C$ 335 and C$ 653 in February. The cheapest round-trip price found within the last 3 days was C$ 347 on Frontier (20 Feb-1 Mar).

Cheap flight deals from Buffalo to San Francisco

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to San Francisco
Explore the most affordable flight options available from Buffalo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 January 2026.

Fri 20/21:29 p.m.

BUF

SFO

1 stop11h 10m

Frontier

Sun 1/311:09 p.m.

SFO

BUF

1 stop10h 44m

Frontier

Deal found 21/1C$ 347

Tue 24/26:15 a.m.

BUF

SFO

1 stop7h 49m

Delta

Wed 25/25:45 a.m.

SFO

BUF

1 stop8h 14m

Delta

Deal found 23/1C$ 355

Tue 21/47:00 a.m.

BUF

SFO

1 stop9h 27m

United Airlines

Sat 25/411:52 p.m.

SFO

BUF

1 stop7h 13m

United Airlines

Deal found 21/1C$ 358

Tue 31/36:15 a.m.

BUF

SFO

1 stop7h 30m

Delta

Thu 16/46:00 a.m.

SFO

BUF

1 stop6h 13m

Delta

Deal found 22/1C$ 363

Thu 26/212:26 p.m.

BUF

SFO

1 stop9h 10m

Delta

Mon 2/310:45 p.m.

SFO

BUF

1 stop9h 58m

Delta

Deal found 20/1C$ 366

Fri 20/24:25 p.m.

BUF

SFO

1 stop9h 16m

American Airlines

Sun 1/311:35 p.m.

SFO

BUF

2 stops10h 16m

American Airlines

Deal found 21/1C$ 372

Mon 13/48:00 p.m.

BUF

SFO

1 stop7h 20m

Southwest

Thu 16/411:25 p.m.

SFO

BUF

1 stop7h 50m

Southwest

Deal found 23/1C$ 395

Tue 28/41:10 p.m.

BUF

SFO

2 stops9h 45m

Southwest

Sun 3/511:25 p.m.

SFO

BUF

1 stop7h 50m

Southwest

Deal found 21/1C$ 402

Tue 21/43:10 p.m.

BUF

SFO

1 stop11h 25m

Southwest

Sun 26/49:15 p.m.

SFO

BUF

1 stop7h 35m

Southwest

Deal found 21/1C$ 403

Sun 22/26:15 a.m.

BUF

SFO

1 stop7h 49m

Delta

Wed 25/25:45 a.m.

SFO

BUF

1 stop8h 14m

Delta

Deal found 23/1C$ 412

Thu 26/26:00 a.m.

BUF

SFO

1 stop9h 57m

JetBlue

Mon 2/37:00 a.m.

SFO

BUF

1 stop8h 35m

JetBlue

Deal found 22/1C$ 414

Tue 7/77:35 p.m.

BUF

SFO

1 stop7h 10m

Delta

Fri 31/711:45 p.m.

SFO

BUF

1 stop8h 55m

Delta

Deal found 22/1C$ 416

Best flights from Buffalo to San Francisco
Discover carefully curated flight deals from Buffalo to San Francisco that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 23 January 2026.

Tue 3/37:00 a.m.

BUF

SFO

1 stop10h 07m

United Airlines

Tue 10/36:45 a.m.

SFO

BUF

1 stop6h 57m

United Airlines

Deal found 21/1C$ 355

Tue 24/26:15 a.m.

BUF

SFO

1 stop7h 49m

Delta

Wed 25/25:45 a.m.

SFO

BUF

1 stop8h 14m

Delta

Deal found 23/1C$ 355

Fri 22/512:25 p.m.

BUF

SFO

1 stop11h 48m

JetBlue

Mon 25/511:59 p.m.

SFO

BUF

1 stop8h 30m

JetBlue

Deal found 23/1C$ 363

Tue 21/43:10 p.m.

BUF

SFO

1 stop11h 25m

Southwest

Sun 26/49:15 p.m.

SFO

BUF

1 stop7h 35m

Southwest

Deal found 21/1C$ 403

Wed 22/47:00 a.m.

BUF

SFO

1 stop9h 27m

United Airlines

Mon 27/411:52 p.m.

SFO

BUF

1 stop7h 20m

United Airlines

Deal found 21/1C$ 358

Wed 8/77:35 p.m.

BUF

SFO

1 stop7h 10m

Delta

Tue 28/76:15 a.m.

SFO

BUF

1 stop9h 18m

Delta

Deal found 22/1C$ 363

Mon 13/46:00 a.m.

BUF

SFO

1 stop10h 56m

JetBlue

Fri 17/48:00 a.m.

SFO

BUF

1 stop10h 59m

JetBlue

Deal found 23/1C$ 363

Thu 19/31:00 p.m.

BUF

SFO

1 stop9h 07m

Delta

Mon 23/311:35 p.m.

SFO

BUF

1 stop8h 26m

Delta

Deal found 21/1C$ 363

Thu 23/47:45 p.m.

BUF

SFO

1 stop8h 32m

United Airlines

Tue 28/410:50 p.m.

SFO

BUF

1 stop8h 22m

United Airlines

Deal found 20/1C$ 363

Thu 9/410:32 a.m.

BUF

SFO

1 stop7h 10m

Delta

Sun 19/49:35 p.m.

SFO

BUF

1 stop10h 26m

Delta

Deal found 22/1C$ 363

Thu 26/212:26 p.m.

BUF

SFO

1 stop9h 10m

Delta

Mon 2/310:45 p.m.

SFO

BUF

1 stop9h 58m

Delta

Deal found 20/1C$ 366

Sun 22/26:15 a.m.

BUF

SFO

1 stop7h 49m

Delta

Wed 25/25:45 a.m.

SFO

BUF

1 stop8h 14m

Delta

Deal found 23/1C$ 412

Last-minute flights from Buffalo to San Francisco
Discover last-minute flight deals from Buffalo to San Francisco. Data last updated 23 January 2026 and is based on user searches.

Wed 4/29:30 a.m.

BUF

SFO

1 stop28h 00m

JetBlue

Wed 18/26:30 a.m.

SFO

BUF

1 stop11h 11m

JetBlue

Deal found 22/1C$ 518

Sat 7/27:00 a.m.

BUF

SFO

1 stop10h 07m

JetBlue

Wed 11/211:59 p.m.

SFO

BUF

1 stop9h 14m

JetBlue

Deal found 23/1C$ 493

Fri 20/21:29 p.m.

BUF

SFO

1 stop11h 10m

Frontier

Sun 1/311:09 p.m.

SFO

BUF

1 stop10h 44m

Frontier

Deal found 21/1C$ 347

Fri 20/24:25 p.m.

BUF

SFO

1 stop9h 16m

American Airlines

Sun 1/311:35 p.m.

SFO

BUF

2 stops10h 16m

American Airlines

Deal found 21/1C$ 372

Fri 20/25:44 p.m.

BUF

SFO

1 stop8h 41m

Delta

Sat 21/25:45 a.m.

SFO

BUF

1 stop8h 14m

Delta

Deal found 22/1C$ 471

Sun 22/26:15 a.m.

BUF

SFO

1 stop7h 49m

Delta

Wed 25/25:45 a.m.

SFO

BUF

1 stop8h 14m

Delta

Deal found 23/1C$ 412

Sun 22/26:15 a.m.

BUF

SFO

1 stop7h 49m

Delta

Thu 26/212:14 p.m.

SFO

BUF

1 stop7h 43m

Delta

Deal found 23/1C$ 468

Tue 24/26:15 a.m.

BUF

SFO

1 stop7h 49m

Delta

Wed 25/25:45 a.m.

SFO

BUF

1 stop8h 14m

Delta

Deal found 23/1C$ 355

Tue 24/28:00 a.m.

BUF

SFO

1 stop9h 15m

JetBlue

Thu 26/28:20 a.m.

SFO

BUF

1 stop10h 05m

JetBlue

Deal found 23/1C$ 363

Thu 26/212:26 p.m.

BUF

SFO

1 stop9h 10m

Delta

Mon 2/310:45 p.m.

SFO

BUF

1 stop9h 58m

Delta

Deal found 20/1C$ 366

Thu 26/26:00 a.m.

BUF

SFO

1 stop9h 57m

JetBlue

Mon 2/37:00 a.m.

SFO

BUF

1 stop8h 35m

JetBlue

Deal found 22/1C$ 414

One-way flights from Buffalo to San Francisco
Search for one-way flight options from Buffalo to San Francisco. Find affordable one-way fares based on user searches. Data last updated 23 January 2026.

Sun 22/25:40 a.m.

BUF

SFO

1 stop8h 15m

Southwest

Deal found 23/1C$ 182

Wed 13/51:10 p.m.

BUF

SFO

2 stops9h 45m

Southwest

Deal found 21/1C$ 189

Mon 6/47:35 p.m.

BUF

SFO

1 stop7h 30m

Southwest

Deal found 23/1C$ 214

Sun 22/26:07 p.m.

BUF

SFO

3 stops54h 32m

Multiple Airlines

Deal found 23/1C$ 250

Sat 7/39:25 p.m.

BUF

SFO

2 stops50h 13m

Frontier

Deal found 21/1C$ 254

Sun 22/26:07 p.m.

BUF

SFO

2 stops54h 32m

Frontier

Deal found 23/1C$ 261

Thu 5/36:10 a.m.

BUF

SFO

2 stops10h 40m

Southwest

Deal found 21/1C$ 273

Sun 26/47:50 p.m.

BUF

SFO

1 stop7h 20m

Southwest

Deal found 22/1C$ 276

Wed 4/21:59 p.m.

BUF

SFO

1 stop8h 10m

United Airlines

Deal found 21/1C$ 280

Tue 17/210:30 a.m.

BUF

SFO

2 stops11h 20m

Southwest

Deal found 21/1C$ 311

Sat 14/25:44 p.m.

BUF

SFO

1 stop8h 41m

Delta

Deal found 21/1C$ 344

Thu 29/111:24 a.m.

BUF

SFO

1 stop9h 10m

United Airlines

Deal found 22/1C$ 351

Find flight deals from Buffalo to San Francisco

Round-trip from	C$ 347
One-way from	C$ 182
Popular in	December
Cheapest in	January
Average price	C$ 362

Frontier
20/2-1/3
2 total stops
21h 54m total
Buffalo to San Francisco

Search Deals

United Airlines
6/3
1 total stop
8h 58m total
Buffalo to San Francisco

Search Deals

High demand for flights, 0% potential price rise

Search Deals

Cheapest flight prices on average. 1% potential price decrease (C$ 10 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in January 2026

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to San Francisco that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Tue 3/3

7:00 a.m.-2:07 p.m.

1 stop10h 07m

San Francisco

Tue 10/3

6:45 a.m.-4:42 p.m.

1 stop6h 57m

C$ 355

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Tue 24/2

6:15 a.m.-11:04 a.m.

1 stop7h 49m

San Francisco

Wed 25/2

5:45 a.m.-4:59 p.m.

1 stop8h 14m

C$ 355

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Wed 22/4

7:00 a.m.-1:27 p.m.

1 stop9h 27m

San Francisco

Mon 27/4

11:52 p.m.-10:12 a.m.

1 stop7h 20m

C$ 358

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Fri 22/5

12:25 p.m.-9:13 p.m.

1 stop11h 48m

San Francisco

Mon 25/5

11:59 p.m.-11:29 a.m.

1 stop8h 30m

C$ 363

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Wed 8/7

7:35 p.m.-11:45 p.m.

1 stop7h 10m

San Francisco

Tue 28/7

6:15 a.m.-6:33 p.m.

1 stop9h 18m

C$ 363

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Mon 13/4

6:00 a.m.-1:56 p.m.

1 stop10h 56m

San Francisco

Fri 17/4

8:00 a.m.-9:59 p.m.

1 stop10h 59m

C$ 363

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Thu 19/3

1:00 p.m.-7:07 p.m.

1 stop9h 07m

San Francisco

Mon 23/3

11:35 p.m.-11:01 a.m.

1 stop8h 26m

C$ 363

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Thu 23/4

7:45 p.m.-1:17 a.m.

1 stop8h 32m

San Francisco

Tue 28/4

10:50 p.m.-10:12 a.m.

1 stop8h 22m

C$ 363

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Thu 9/4

10:32 a.m.-2:42 p.m.

1 stop7h 10m

San Francisco

Sun 19/4

9:35 p.m.-11:01 a.m.

1 stop10h 26m

C$ 363

BuffaloSan Francisco

BUF - SFO

BUFSFO

Buffalo

Thu 26/2

12:26 p.m.-6:36 p.m.

1 stop9h 10m

San Francisco

Mon 2/3

10:45 p.m.-11:43 a.m.

1 stop9h 58m

C$ 366

Flights are sorted by cheapest round-trip flights first.

Deals found on 23/1

Showing 1-10 of 24 results

Best time to book a flight from Buffalo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Buffalo with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to San Francisco

Prices

How far ahead should I book a flight from Buffalo to San Francisco?

To ensure you get the cheapest price possible for a flight from Buffalo to San Francisco, you should look to book at least 56 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Buffalo to San Francisco?

Currently, March is the cheapest month in which you can book a flight from Buffalo to San Francisco (average of C$ 204). Flying from Buffalo to San Francisco in December is currently the most expensive (average of C$ 333). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to San Francisco?

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Buffalo to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,267 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Southwest

8.0

Very good

4,267 reviews

Southwest

8.0

Very good

4,267 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Delta

7.9

Good

8,093 reviews

Southwest

8.0

Very good

4,267 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

United Airlines

7.4

Good

9,195 reviews

Southwest

8.0

Very good

4,267 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

American Airlines

7.2

Good

11,176 reviews

Southwest

8.0

Very good

4,267 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Frontier

5.7

Fair

3,057 reviews

Southwest

8.0

Very good

4,267 reviews

Check prices

Reviews

1 / 20

8.0

Excellent

Walter,Aug 2025

OAK - SAN

Related info for your journey

How long is the flight from Buffalo to San Francisco?
Frontier, United Airlines, and Delta can get you from Buffalo to San Francisco in just under 9h 07m. Your travel time can differ by up to 2h 03m. Airlines will cover a distance of 3705 km. This flight may include one or multiple stops.
What are the cheapest airlines flying from Buffalo to San Francisco round-trip?
Frontier, at C$ 154, was found to be the cheapest airline from Buffalo to San Francisco.Alternate airlines to your destination round-trip include United Airlines and Delta. Users have found that Frontier is 67% cheaper than the other options available to this destination.
Can I find deals for flights from Buffalo to San Francisco that include hotel bookings?
Yes. In addition to deals on Buffalo to San Francisco flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Buffalo to San Francisco?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to San Francisco.
Can I find deals for business class flights from Buffalo to San Francisco?
Yes. Cheapflights offers flight deals from Buffalo to San Francisco by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Buffalo to San Francisco?
Currently, March is the cheapest month in which you can book a flight from Buffalo to San Francisco (average of C$ 204). Flying from Buffalo to San Francisco in December is currently the most expensive (average of C$ 333). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from Buffalo to San Francisco

Airline	Cheapest	Average	Flexibility	On-time
Frontier	CheapestC$ 154	AverageC$ 396	FlexibilityNo cancel fee	On-time62%	Search Frontier flights
United Airlines	CheapestC$ 166	AverageC$ 567	FlexibilityNo cancel fee	On-time69%	Search United Airlines flights
Delta	CheapestC$ 191	AverageC$ 440	FlexibilityNo cancel fee	On-timeN/A	Search Delta flights
Southwest	CheapestC$ 225	AverageC$ 420	FlexibilityNo cancel fee	On-time63%	Search Southwest flights
American Airlines	CheapestC$ 263	AverageC$ 384	FlexibilityNo cancel fee	On-time71%	Search American Airlines flights

Fly with Cheapflights

How does Cheapflights help users find flights from Buffalo to San Francisco?

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Can Cheapflights find flights from Buffalo to San Francisco with no change fees?

Need flexible booking options for your flight to San Francisco from Buffalo? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

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Cheap flights from Buffalo to San Francisco from C$ 182

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/4. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Buffalo to San Francisco

Cheapest flights from Buffalo to San FranciscoExplore the most affordable flight options available from Buffalo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 January 2026.

Explore the most affordable flight options available from Buffalo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 January 2026.

Find flight deals from Buffalo to San Francisco

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to San Francisco that are best for you.

Best time to book a flight from Buffalo to San Francisco

Have a flexible travel schedule? Discover the best time to fly to San Francisco from Buffalo with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to San Francisco

How far ahead should I book a flight from Buffalo to San Francisco?

What is the cheapest month to book a flight from Buffalo to San Francisco?

How much does it cost to fly round-trip from Buffalo to San Francisco?

What’s the top layover airport for flights from Buffalo to San Francisco?

What’s the cheapest layover airport for flights from Buffalo to San Francisco?

What’s the fastest layover option from Buffalo to San Francisco?

Which airport typically offers the quickest layover for flights from Buffalo to San Francisco?

Reviews of airlines servicing San Francisco

Get a feel of what it's like to fly with Southwest,Delta, andUnited Airlines from Buffalo to San Francisco by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to San Francisco. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Buffalo to San Francisco?

What are the cheapest airlines flying from Buffalo to San Francisco round-trip?

Can I find deals for flights from Buffalo to San Francisco that include hotel bookings?

How can I find direct flights from Buffalo to San Francisco?

Can I find deals for business class flights from Buffalo to San Francisco?

What is the cheapest month to book a flight from Buffalo to San Francisco?

Travelling to a place near San Francisco?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Buffalo to San Francisco

See prices for flight routes from nearby airports that may be better suited for you.

Top 5 airlines flying from Buffalo to San Francisco

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Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

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Cheapest flights from Buffalo to San Francisco
Explore the most affordable flight options available from Buffalo to San Francisco. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 January 2026.