How often are flights from Mexico City to Panama City delayed?

About 4% of weekly flights between Mexico City and Panama City have experienced delays in the past year, with the average delay time being 119 minutes.

What is the most punctual flight time for Mexico City to Panama City flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Saturday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Mexico City to Panama City flights?

Over the past year, Copa Airlines has had the lowest number of delays on this route, with just 4% of flights being delayed.

How popular is this Mexico City to Panama City flight route?

Flights from Mexico City Benito Juarez to Panama City Tocumen Intl have been viewed 5 times in the past calendar month.

How long is the flight from Mexico City to Panama City?

There are many flights that can get you from Mexico City to Panama City in 3h 41m. Fly via Aeromexico or Copa Airlines to get the fastest option. The distance between Mexico City and Panama City is about 2409 km. Most flights are nonstop.

What is the cheapest airline to fly from Mexico City to Panama City round-trip?

Flying on Copa Airlines is currently your cheapest option to Panama City, with prices starting at C$ 502. Users have found that Copa Airlines is 9% cheaper than the other options available to this destination.

Weekly flight availability from Mexico City to Panama City

The most flights from MEX to PTY are scheduled on a Monday (9 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (6 on average).

In terms of precipitation, rainfall in Panama City ranges from 10.0 - 340.0 mm per month. October is typically the wettest month, when rainfall can reach 340.0 mm. February is typically the driest time to visit Panama City when rainfall is around 10.0 mm.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 26.0 C).

What are the cheapest flights from Mexico City to Panama City?

The cheapest flight price from Mexico City to Panama City is C$ 471. On average you can expect to pay C$ 799. The most popular route, (Mexico City Benito Juarez - Panama City Tocumen Intl), can usually be booked for C$ 691.

What are the most reliable airlines from Mexico City to Panama City?

Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mexico City to Panama City on time: Emirates (95%), Aeromexico (95%), AeroMexico Connect (95%).

What airports do I use to fly from Mexico City to Panama City?

Booking a flight from Mexico City Benito Juarez (MEX) to Panama City Tocumen Intl (PTY) is your only option if you wish to fly from Mexico City to Panama City. On a typical day, there are 8 flights from Benito Juarez to Tocumen Intl, all of which are around 3h 43m for a nonstop flight. You can also purchase a plane ticket from 1 airline when you book a flight from Benito Juarez to Panama City.

Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Mexico City to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

Can I find deals for business class flights from Mexico City to Panama City?

Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 234+ Cheap Flights from Mexico City to Panama City

Cheapflights Tip: The best prices from Mexico City Benito Juarez to Panama City Tocumen Intl are usually found in February or January, booked 90 days in advance, depart on a Monday or Saturday and return on a Monday

Cheap flight deals from Mexico City to Panama City

Enter your travel dates to find the best prices.

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Direct

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Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 September 2026.

Sun 4/109:05 a.m. -

Nonstop3h 50m

Sun 11/103:05 p.m. -

Nonstop3h 55m

Deal found 5/9C$ 489

Fri 25/123:30 p.m. -

Nonstop3h 50m

Wed 30/1211:44 a.m. -

Nonstop3h 46m

Deal found 7/9C$ 525

Thu 24/92:10 a.m. -

Nonstop3h 41m

Mon 5/107:12 p.m. -

Nonstop3h 53m

Deal found 8/9C$ 545

Wed 4/111:20 a.m. -

Nonstop3h 44m

Sun 15/114:29 p.m. -

Nonstop3h 51m

Deal found 10/9C$ 560

Wed 23/129:10 a.m. -

Nonstop3h 51m

Sat 26/129:19 a.m. -

Nonstop3h 51m

Deal found 7/9C$ 600

Fri 18/123:30 p.m. -

Nonstop3h 50m

Wed 23/129:19 a.m. -

Nonstop3h 51m

Deal found 7/9C$ 614

Fri 6/114:55 p.m. -

1 stop8h 15m

Tue 10/116:10 p.m. -

1 stop10h 00m

Deal found 9/9C$ 678

Tue 27/102:00 a.m. -

Nonstop3h 41m

Sun 1/117:18 p.m. -

Nonstop4h 07m

Deal found 10/9C$ 684

Mon 21/129:10 a.m. -

Nonstop3h 51m

Mon 4/19:21 a.m. -

Nonstop3h 49m

Deal found 6/9C$ 721

Sun 11/109:50 a.m. -

Nonstop3h 48m

Sun 11/109:28 p.m. -

Nonstop3h 47m

Deal found 7/9C$ 740

Fri 25/121:10 p.m. -

Nonstop3h 50m

Fri 1/19:27 p.m. -

Nonstop3h 48m

Deal found 8/9C$ 750

Find flight deals from Mexico City to Panama City

Round-trip from	C$ 489
One-way from	C$ 234
Popular in	July
Cheapest in	February
Average price	C$ 580
Good round-trip deal	C$ 601 or less

Aeromexico
4/10-11/10
Nonstop
7h 45m total
Mexico City to Panama City

Search Deals

Copa Airlines
25/12-31/12
Nonstop
3h 50m total
Mexico City to Panama City

Search Deals

Highest demand for flights based on searches. 2% potential increase in price (C$ 16 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease (C$ 9 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2026

Search Deals

Price to beat on a round-trip flight from Mexico City Benito Juarez to Panama City Tocumen Intl.

Search Deals

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Fri 25/12

3:30 p.m.-8:20 p.m.

Nonstop3h 50m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 234

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Mon 2/11

8:50 a.m.-1:46 p.m.

Nonstop3h 56m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 334

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Fri 19/2

1:10 p.m.-5:52 p.m.

Nonstop3h 42m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 349

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Sun 8/11

9:10 a.m.-2:03 p.m.

Nonstop3h 53m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 349

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Wed 6/1

3:25 a.m.-8:05 a.m.

Nonstop3h 40m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 349

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Sun 15/11

1:20 a.m.-6:04 a.m.

Nonstop3h 44m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 349

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Tue 26/1

3:30 p.m.-8:17 p.m.

Nonstop3h 47m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 349

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Wed 10/2

5:55 a.m.-10:40 a.m.

Nonstop3h 45m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 349

Quickest round-trip

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Fri 5/3

2:00 a.m.-6:34 a.m.

Nonstop3h 34m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 349

Mexico CityPanama City

MEX Mexico City Benito Juarez - PTY Panama City Tocumen Intl

MEXPTY

Mexico City Benito Juarez

Wed 6/1

1:10 p.m.-5:58 p.m.

Nonstop3h 48m

Panama City Tocumen Intl

Wed 31/12

12:00 a.m.-11:00 p.m.

Nonstop0h 00m

C$ 349

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 21 resultsSorted by cheapest first

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.

MEX-PTY

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Panama City

Prices

Airlines

Delays

How far ahead should I book a flight from Mexico City to Panama City?

To ensure you get the cheapest price possible for a flight from Mexico City to Panama City, you should look to book at least 89 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mexico City to Panama City?

Currently, February is the cheapest month in which you can book a flight from Mexico City to Panama City (average of C$ 503). Flying from Mexico City to Panama City in July is currently the most expensive (average of C$ 615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to PTY?

It’s typically best to fly out from Mexico City to Panama City at noon. Doing so could potentially save you 38% on the flight price compared to flying in the afternoon, which is usually more expensive.

How much does it cost to fly round-trip from Mexico City to Panama City?

Airfare is below average for this route at the moment.

Mexico City to Panama City flights typically cost between C$ 517 and C$ 797 in October.
The cheapest round-trip price found within the last 5 days was C$ 489 on Aeromexico (4 Oct-11 Oct).

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Copa Airlines from Mexico City to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Copa Airlines

7.6

Good

1,546 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Anonymous,Jul 2026

BOS - PTY

Airline was delayed 1 hour, that made my layover flight be missed, gave wrong information about gates, they closed the gates in my face, rebooked me, and had business class, and rebooked me not business class

Copa Airlines

7.6

Good

1,546 reviews

Copa Airlines

7.6

Good

1,546 reviews

Check prices

Reviews

1 / 20

2.0

Mediocre

Anonymous,Jul 2026

BOS - PTY

Related info for your journey

What airports do I use to fly from Mexico City to Panama City?
Booking a flight from Mexico City Benito Juarez (MEX) to Panama City Tocumen Intl (PTY) is your only option if you wish to fly from Mexico City to Panama City. On a typical day, there are 8 flights from Benito Juarez to Tocumen Intl, all of which are around 3h 43m for a nonstop flight. You can also purchase a plane ticket from 1 airline when you book a flight from Benito Juarez to Panama City.
How popular is this Mexico City to Panama City flight route?
Flights from Mexico City Benito Juarez to Panama City Tocumen Intl have been viewed 5 times in the past calendar month.
How long is the flight from Mexico City to Panama City?
There are many flights that can get you from Mexico City to Panama City in 3h 41m. Fly via Aeromexico or Copa Airlines to get the fastest option. The distance between Mexico City and Panama City is about 2409 km. Most flights are nonstop.
What is the cheapest airline to fly from Mexico City to Panama City round-trip?
Flying on Copa Airlines is currently your cheapest option to Panama City, with prices starting at C$ 502. Users have found that Copa Airlines is 9% cheaper than the other options available to this destination.
What are the most reliable airlines from Mexico City to Panama City?
Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mexico City to Panama City on time: Emirates (95%), Aeromexico (95%), AeroMexico Connect (95%).
What are the cheapest flights from Mexico City to Panama City?
The cheapest flight price from Mexico City to Panama City is C$ 471. On average you can expect to pay C$ 799. The most popular route, (Mexico City Benito Juarez - Panama City Tocumen Intl), can usually be booked for C$ 691.
Can I find deals for flights from Mexico City to Panama City that include hotel bookings?
Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Mexico City to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.
Can I find deals for business class flights from Mexico City to Panama City?
Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Mexico City to Panama City?
Currently, February is the cheapest month in which you can book a flight from Mexico City to Panama City (average of C$ 503). Flying from Mexico City to Panama City in July is currently the most expensive (average of C$ 615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Complete your trip

Direct flights to Panama

Flights by cabin class

Other flight options

Other flights from Mexico City

Panama City flight routes

Popular flights

Complete your trip

Panama City car rentals

Panama City Tocumen Intl Airport car rentals

Casco Viejo car rentals

Ancón car rentals

San Francisco car rentals

Bella Vista car rentals

Bethania car rentals

Parque Lefevre car rentals

Juan Diaz car rentals

Calidonia car rentals

Santa Ana car rentals

Pueblo Nuevo car rentals

Top airline flying from Mexico City to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Copa Airlines	CheapestC$ 502	AverageC$ 596	FlexibilityNo cancel fee	On-time70%	Search Copa Airlines flights

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How does Cheapflights help users find flights from Mexico City to Panama City?

Cheapflights makes it easy to find Mexico City to Panama City flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Mexico City to Panama City?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Mexico City to Panama City.

Can Cheapflights find flights from Mexico City to Panama City with no change fees?

Yes! Cheapflights helps users easily find flights from Mexico City to Panama City with no change fees.

Can Cheapflights notify me if prices for flights from Mexico City to Panama City become cheaper?

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Cheap flights from Mexico City to Panama City from C$ 234

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/12. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama CityExplore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 September 2026.

Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 September 2026.

Best flights from Mexico City to Panama CityDiscover carefully curated flight deals from Mexico City to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 10 September 2026.

Discover carefully curated flight deals from Mexico City to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 10 September 2026.

Direct flights from Mexico City to Panama CityExplore direct flight options from Mexico City to Panama City based on user searches, and compare prices and availability for your desired travel dates. Data last updated 10 September 2026.

Explore direct flight options from Mexico City to Panama City based on user searches, and compare prices and availability for your desired travel dates. Data last updated 10 September 2026.

Last-minute flights from Mexico City to Panama CityDiscover last-minute flight deals from Mexico City to Panama City. Data last updated 10 September 2026 and is based on user searches.

Discover last-minute flight deals from Mexico City to Panama City. Data last updated 10 September 2026 and is based on user searches.

One-way flights from Mexico City to Panama CitySearch for one-way flight options from Mexico City to Panama City. Find affordable one-way fares based on user searches. Data last updated 10 September 2026.

Search for one-way flight options from Mexico City to Panama City. Find affordable one-way fares based on user searches. Data last updated 10 September 2026.

Find flight deals from Mexico City to Panama City

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One-way from

Popular in

Cheapest in

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Good round-trip deal

Cheapflights Fare Finder

Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.

Cheapflights Insights

How far ahead should I book a flight from Mexico City to Panama City?

To ensure you get the cheapest price possible for a flight from Mexico City to Panama City, you should look to book at least 89 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mexico City to Panama City?

What is the cheapest time of day to fly from MEX to PTY?

It’s typically best to fly out from Mexico City to Panama City at noon. Doing so could potentially save you 38% on the flight price compared to flying in the afternoon, which is usually more expensive.

How much does it cost to fly round-trip from Mexico City to Panama City?

Airfare is below average for this route at the moment.

Mexico City to Panama City flights typically cost between C$ 517 and C$ 797 in October.The cheapest round-trip price found within the last 5 days was C$ 489 on Aeromexico (4 Oct-11 Oct).

Weekly flight availability from Mexico City to Panama City

The most flights from MEX to PTY are scheduled on a Monday (9 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (6 on average).

How often are flights from Mexico City to Panama City delayed?

About 4% of weekly flights between Mexico City and Panama City have experienced delays in the past year, with the average delay time being 119 minutes.

What is the most punctual flight time for Mexico City to Panama City flights?

Historically, flights departing at night are less likely to be delayed, whereas flights leaving in the early afternoon tend to experience delays more often.

What day of the week experiences the fewest flight delays on this route?

Saturday tends to have the lowest number of delays on this route, whereas Wednesday has historically faced a higher average of delays compared to other days of the week.

Which airline has the best punctuality record on Mexico City to Panama City flights?

Over the past year, Copa Airlines has had the lowest number of delays on this route, with just 4% of flights being delayed.

Reviews of airlines servicing Panama City

Get a feel of what it's like to fly with Copa Airlines from Mexico City to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airports do I use to fly from Mexico City to Panama City?

How popular is this Mexico City to Panama City flight route?

How long is the flight from Mexico City to Panama City?

What is the cheapest airline to fly from Mexico City to Panama City round-trip?

What are the most reliable airlines from Mexico City to Panama City?

What are the cheapest flights from Mexico City to Panama City?

Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

How can I find direct flights from Mexico City to Panama City?

Can I find deals for business class flights from Mexico City to Panama City?

What is the cheapest month to book a flight from Mexico City to Panama City?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Complete your trip

Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.

Direct flights to Panama

Book a non-stop flight to one of these other cities located in Panama.

Search flights from Mexico City to Panama City by cabin class

Find flights from Mexico City to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Mexico City and Panama City flights

Browse other Mexico City and Panama City flight options. Last updated on 10 September 2026.

Other flights from Mexico City

Browse through other flights departing from Mexico City. Flights are based on user searches made on Cheapflights and were last updated on 10 September 2026.

Other flights to Panama City

Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 10 September 2026.

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Top airline flying from Mexico City to Panama City

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How does Cheapflights help users find flights from Mexico City to Panama City?

Why should you use Cheapflights to find cheap flight tickets from Mexico City to Panama City?

Can Cheapflights find flights from Mexico City to Panama City with no change fees?

Can Cheapflights notify me if prices for flights from Mexico City to Panama City become cheaper?

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Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 10 September 2026.

Best flights from Mexico City to Panama City
Discover carefully curated flight deals from Mexico City to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 10 September 2026.

Direct flights from Mexico City to Panama City
Explore direct flight options from Mexico City to Panama City based on user searches, and compare prices and availability for your desired travel dates. Data last updated 10 September 2026.

Last-minute flights from Mexico City to Panama City
Discover last-minute flight deals from Mexico City to Panama City. Data last updated 10 September 2026 and is based on user searches.

One-way flights from Mexico City to Panama City
Search for one-way flight options from Mexico City to Panama City. Find affordable one-way fares based on user searches. Data last updated 10 September 2026.

Mexico City to Panama City flights typically cost between C$ 517 and C$ 797 in October.
The cheapest round-trip price found within the last 5 days was C$ 489 on Aeromexico (4 Oct-11 Oct).