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Cheap flights from Mexico City to Panama City from C$ 194

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/10. Fares are subject to change and may not be available on all flights or dates of travel.
MEX — PTY
3 Aug — 10 Aug1
1 adult

Cheapflights Tip: The best prices from Mexico City Benito Juarez to Panama City Tocumen Intl are usually found in July or June, booked 85 days in advance, depart on a Wednesday or Sunday and return on a Monday

Cheap flight deals from Mexico City to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Mexico City (MEX) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 29 July 2025.

Round-trip from

C$ 451

One-way from

C$ 194

Popular in

September

Cheapest in

July

Average price

C$ 484

Good one-way deal

C$ 286 or less
Copa Airlines
  • Copa Airlines
  • 1/10-8/10
  • Nonstop
  • 7h 24m total
  • Mexico City to Panama City
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Avianca
  • Avianca
  • 13/10
  • 1 total stop
  • 19h 30m total
  • Mexico City to Panama City
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Highest demand for flights based on searches. 8% potential increase in price (C$ 75 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 10 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Price to beat on a one-way flight from Mexico City Benito Juarez to Panama City Tocumen Intl.
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Find flight deals from Mexico City to Panama City

Cheapest flights from Mexico City to Panama City
Explore the most affordable flight options available from Mexico City to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 29 July 2025.

Wed 1/101:05 p.m.MEX - PTY
Nonstop3h 45mCopa Airlines
Wed 8/1010:21 p.m.PTY - MEX
Nonstop3h 39mCopa Airlines
Deal found 28/7C$ 451
Thu 16/1012:40 a.m.MEX - PTY
1 stop8h 30mAvianca
Thu 23/1011:20 a.m.PTY - MEX
1 stop15h 35mAvianca
Deal found 28/7C$ 535
Thu 16/1012:40 a.m.MEX - PTY
1 stop8h 30mMultiple Airlines
Thu 23/1010:21 p.m.PTY - MEX
Nonstop3h 39mMultiple Airlines
Deal found 28/7C$ 779

Cheapflights Fare Finder

 
Customize your flight search to find flights from Mexico City to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 29 July 2025.
Use the filters below to find and compare flights from Mexico City to Panama City that are best for you.

Fly from

Mexico City

Fly to

Panama City

Route

Depart

Return

Price

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Wed 1/10

1:05 p.m.-5:50 p.m.

Nonstop3h 45m

Panama City Tocumen Intl

Wed 8/10

10:21 p.m.-1:00 a.m.

Nonstop3h 39m

C$ 451

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Thu 16/10

12:40 a.m.-10:10 a.m.

1 stop8h 30m

Panama City Tocumen Intl

Thu 23/10

11:20 a.m.-1:55 a.m.

1 stop15h 35m

C$ 535

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Thu 16/10

12:40 a.m.-10:10 a.m.

1 stop8h 30m

Panama City Tocumen Intl

Thu 23/10

10:21 p.m.-1:00 a.m.

Nonstop3h 39m

C$ 779

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Mon 13/10

12:40 a.m.-9:10 p.m.

1 stop19h 30m

C$ 194

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Fri 29/8

11:15 p.m.-9:10 p.m.

2 stops20h 55m

C$ 282

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Thu 28/8

1:05 p.m.-5:49 p.m.

Nonstop3h 44m

C$ 472

Mexico CityPanama City

MEX - PTY

MEXPTY

Mexico City Benito Juarez

Mon 25/8

4:40 a.m.-7:29 p.m.

2 stops13h 49m

C$ 1,305

Flights are sorted by cheapest round-trip flights first.

Deals found on 28/7

Best time to book a flight from Mexico City to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Mexico City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mexico City to Panama City

How far ahead should I book a flight from Mexico City to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Mexico City to Panama City. Price data was last updated on 25 July 2025.

To ensure you get the cheapest price possible for a flight from Mexico City to Panama City, you should look to book at least 85 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Mexico City to Panama City?

Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City (average of C$ 542). Flying from Mexico City to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MEX to PTY?

Find hourly flight availability from Mexico City to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 29 July 2025.

It’s typically best to fly out from Mexico City to Panama City in the evening. Doing so could potentially save you 47% on the flight price compared to flying at noon, which is usually more expensive.

Weekly flight availability from Mexico City to Panama City

Explore weekly flight availability from Mexico City to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 29 July 2025.

The most flights from MEX to PTY are scheduled on a Wednesday (9 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (2 on average).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated 29 July 2025.
Get a feel of what it's like to fly with Copa Airlines,United Airlines, andAvianca from Mexico City to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.5
Good
1,493 reviews
Check prices

Comfort

7.4

Boarding

7.8

Overall

7.5

Entertainment

6.8

Food

6.8

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Copa Airlines
7.5
Good
1,493 reviews
Copa Airlines
7.5
Good
1,493 reviews
Check prices

Comfort

7.4

Boarding

7.8

Overall

7.5

Entertainment

6.8

Food

6.8

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
United Airlines
7.4
Good
8,896 reviews
Copa Airlines
7.5
Good
1,493 reviews
Check prices

Comfort

7.4

Boarding

7.8

Overall

7.5

Entertainment

6.8

Food

6.8

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.
Avianca
6.7
Okay
2,387 reviews
Copa Airlines
7.5
Good
1,493 reviews
Check prices

Comfort

7.4

Boarding

7.8

Overall

7.5

Entertainment

6.8

Food

6.8

Crew

8.1

Reviews

1 / 20
6.0
Good

Paul,May 2025

PTY - AUA

Had to use my phone for entertainment? Once we landed people were already out their seats and standing in the isles while the plane was still taxiing to the gate. This is unsafe and flight crew had a responsibility to ensure that people remain seated until the pilots turn off the seatbelt sign.

Related info for your journey

Find useful and relevant information for your journey from Mexico City to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Mexico City to Panama City?

    Booking a flight from Mexico City Benito Juarez (MEX) to Panama City Tocumen Intl (PTY) is your only option if you wish to fly from Mexico City to Panama City. On a typical day, there are 5 flights from Benito Juarez to Tocumen Intl, all of which are around 3h 44m for a nonstop flight. You can also purchase a plane ticket from 1 airline when you book a flight from Benito Juarez to Panama City.

  • How popular is this Mexico City to Panama City flight route?

    Flights from Mexico City Benito Juarez to Panama City Tocumen Intl have been viewed 10 times in the past calendar month.

  • What are the cheapest airlines flying from Mexico City to Panama City round-trip?

    Flying on Copa Airlines is currently your cheapest option to Panama City, with prices starting at C$ 451. Another option worth looking into is Avianca, starting at C$ 535 round trip. Users have found that Copa Airlines is 25% cheaper than the other options available to this destination.

  • What are the cheapest airlines to fly from Mexico City to Panama City one-way?

    C$ 194 is the cheapest one-way deal found within the past few days, from Avianca. You may also be able to find cheap deals on Copa Airlines and United Airlines, with prices starting from C$ 472 and C$ 1,305, respectively.

  • What are the most reliable airlines from Mexico City to Panama City?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mexico City to Panama City on time: Emirates (98%), Copa Airlines (97%), Aeromexico (91%).

  • What are the cheapest flights from Mexico City to Panama City?

    The cheapest flight price from Mexico City to Panama City is C$ 286. On average you can expect to pay C$ 550. The most popular route, (Mexico City Benito Juarez - Panama City Tocumen Intl), can usually be booked for C$ 516.

  • Can I find deals for flights from Mexico City to Panama City that include hotel bookings?

    Yes. In addition to deals on Mexico City to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mexico City to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mexico City to Panama City.

  • Can I find deals for business class flights from Mexico City to Panama City?

    Yes. Cheapflights offers flight deals from Mexico City to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mexico City to Panama City?

    Currently, January is the cheapest month in which you can book a flight from Mexico City to Panama City (average of C$ 542). Flying from Mexico City to Panama City in December is currently the most expensive (average of C$ 874). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Mexico City to Panama City

Discover the top airline that operate flights from Mexico City to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 29 July 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapestC$ 486AverageC$ 599FlexibilityNo cancel feeOn-time70%
Search Copa Airlines flights

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How does Cheapflights help users find flights from Mexico City to Panama City?

Cheapflights makes it easy to find Mexico City to Panama City flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Mexico City to Panama City?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Mexico City to Panama City.

Can Cheapflights find flights from Mexico City to Panama City with no change fees?

Yes! Cheapflights helps users easily find flights from Mexico City to Panama City with no change fees.

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