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Cheap flights from Panama City to Mexico City

PTY — MEX
11 Oct — 18 Oct1
1 adult
1 adult, Economy

Cheap flight deals from Panama City to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 11 September 2025.

Popular in

October

Cheapest in

July

Average price

C$ 588

Good round-trip deal

C$ 242 or less
Highest demand for flights based on searches. 4% potential increase in price (C$ 38 potential increase over avg. RT price).
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Cheapest flight prices on average. 0% potential price decrease (C$ 6 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Panama City Tocumen Intl to Mexico City Benito Juarez.
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Best time to book a flight from Panama City to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico City

How far ahead should I book a flight from Panama City to Mexico City?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Mexico City. Price data was last updated on 29 August 2025.

To ensure you get the cheapest price possible for a flight from Panama City to Mexico City, you should look to book at least 69 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Panama City to Mexico City?

Currently, April is the cheapest month in which you can book a flight from Panama City to Mexico City (average of C$ 437). Flying from Panama City to Mexico City in December is currently the most expensive (average of C$ 820). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MEX?

Find hourly flight availability from Panama City to Mexico City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 11 September 2025.

When flying from Panama City to Mexico City, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 47% versus a flight at noon.

Reviews of airlines servicing Mexico City

Get insights into the airlines that provide service to Mexico City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico City. Reviews last updated 11 September 2025.
Read reviews from past customers who have flown Copa Airlines from Panama City to Mexico City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Copa Airlines
7.6
Good
1,531 reviews
Check prices

Entertainment

6.8

Food

6.8

Overall

7.6

Comfort

7.4

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip
Copa Airlines
7.6
Good
1,531 reviews
Copa Airlines
7.6
Good
1,531 reviews
Check prices

Entertainment

6.8

Food

6.8

Overall

7.6

Comfort

7.4

Crew

8.1

Boarding

7.8

Reviews

1 / 20
4.0
Okay

Juan Pablo,Sep 2025

PTY - VVI

not a good expirience, the plane was packed, the seats wear very unconftrable, coudent conect with the entratainmente service on the plane, the onboarding was in charge of a very angry lady i really had a unplesent trip

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Panama City to Mexico City flight route?

    Flights from Panama City Tocumen Intl to Mexico City Benito Juarez have been viewed 2 times in the past calendar month.

  • What is the cheapest airline to fly from Panama City to Mexico City round-trip?

    Cheapflights users have booked flights from Panama City to Mexico City round-trip from C$ 338. Copa Airlines is priced at 40% lower than the current average price of a flight leaving 3 months from now.

  • What are the most reliable airlines from Panama City to Mexico City?

    The top 3 most reliable airlines when flying from Panama City to Mexico City are AeroMexico Connect (100%), Emirates (96%) and Copa Airlines (90%).

  • Can I find deals for flights from Panama City to Mexico City that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico City.

  • Can I find deals for business class flights from Panama City to Mexico City?

    Yes. Cheapflights offers flight deals from Panama City to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Mexico City?

    Currently, April is the cheapest month in which you can book a flight from Panama City to Mexico City (average of C$ 437). Flying from Panama City to Mexico City in December is currently the most expensive (average of C$ 820). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama City to Mexico City

Discover the top airline that operate flights from Panama City to Mexico City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 11 September 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapestC$ 338AverageC$ 608FlexibilityNo cancel feeOn-time70%
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Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City to Mexico City?

Cheapflights helps you search for flights from Panama City to Mexico City via 900+ travel sites so you don’t have to. After performing a flight search, users can also filter their flight selection by filtering for price, number of stops, airlines, and so on.

Why should you use Cheapflights to find cheap flight tickets from Panama City to Mexico City?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Panama City to Mexico City.

Can Cheapflights find flights from Panama City to Mexico City with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Panama City to Mexico City, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Panama City to Mexico City become cheaper?

Not ready to book yet? You can track prices for flights from Panama City to Mexico City on Cheapflights with our Price Alert feature and get notified when better prices are available.

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