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Cheap flights from Santiago to Mexico City from C$ 382

SCL — MEX
11 Oct — 18 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Mexico City

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Mexico City

Sun 27/91:06 a.m. -
1 stop20h 59m
Wed 21/102:10 a.m. -
1 stop15h 22m
Deal found 10/9C$ 738
Thu 24/1212:20 p.m. -
1 stop13h 05m
Wed 6/11:20 a.m. -
1 stop15h 58m
Deal found 7/9C$ 759
Wed 16/95:14 a.m. -
1 stop22h 46m
Thu 24/95:50 a.m. -
1 stop15h 32m
Deal found 6/9C$ 834
Sun 13/125:07 a.m. -
1 stop19h 58m
Wed 13/13:25 a.m. -
1 stop17h 15m
Deal found 11/9C$ 869
Mon 21/93:14 a.m. -
1 stop22h 46m
Wed 7/105:50 a.m. -
1 stop14h 49m
Deal found 7/9C$ 871
Fri 18/91:30 a.m. -
1 stop13h 40m
Mon 5/104:55 a.m. -
1 stop16h 25m
Deal found 7/9C$ 885
Thu 31/1212:20 p.m. -
1 stop13h 05m
Fri 8/13:25 a.m. -
1 stop20h 28m
Deal found 11/9C$ 903
Tue 8/95:14 a.m. -
1 stop16h 51m
Tue 22/93:30 p.m. -
1 stop29h 52m
Deal found 7/9C$ 906
Thu 10/93:14 a.m. -
1 stop18h 51m
Fri 18/91:10 p.m. -
1 stop11h 46m
Deal found 10/9C$ 941
Fri 16/1012:23 p.m. -
1 stop15h 37m
Sat 24/101:20 a.m. -
1 stop19h 19m
Deal found 10/9C$ 991
Sun 20/123:19 a.m. -
1 stop19h 01m
Tue 5/15:55 a.m. -
1 stop14h 45m
Deal found 11/9C$ 998

Find flight deals from Santiago to Mexico City

Round-trip from

C$ 738

One-way from

C$ 382

Popular in

June

Cheapest in

March

Average price

C$ 937
Copa Airlines
  • Copa Airlines
  • 21/10-27/10
  • 2 total stops
  • 40h 40m total
  • Santiago to Mexico City
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Copa Airlines
  • Copa Airlines
  • 23/12-31/12
  • 1 total stop
  • 21h 17m total
  • Santiago to Mexico City
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (C$ 129 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Mon 16/11

3:19 a.m.-12:10 p.m.

1 stop11h 51m

Mexico City Benito Juarez

Wed 31/12

12:00 a.m.-3:00 a.m.

Nonstop0h 00m

C$ 446

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Sat 7/11

3:19 a.m.-10:05 p.m.

1 stop21h 46m

Mexico City Benito Juarez

Wed 31/12

12:00 a.m.-3:00 a.m.

Nonstop0h 00m

C$ 446

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Mon 23/11

5:07 a.m.-12:15 a.m.

1 stop22h 08m

Mexico City Benito Juarez

Wed 31/12

12:00 a.m.-3:00 a.m.

Nonstop0h 00m

C$ 446

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Wed 18/11

3:19 a.m.-12:15 a.m.

1 stop23h 56m

Mexico City Benito Juarez

Wed 31/12

12:00 a.m.-3:00 a.m.

Nonstop0h 00m

C$ 446

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Tue 17/11

1:22 a.m.-10:05 p.m.

1 stop23h 43m

Mexico City Benito Juarez

Wed 31/12

12:00 a.m.-3:00 a.m.

Nonstop0h 00m

C$ 446

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Thu 17/9

3:56 a.m.-10:05 p.m.

1 stop21h 09m

Mexico City Benito Juarez

Wed 31/12

12:00 a.m.-3:00 a.m.

Nonstop0h 00m

C$ 522

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Tue 20/10

3:57 a.m.-10:05 p.m.

1 stop21h 08m

Mexico City Benito Juarez

Tue 27/10

9:25 a.m.-2:46 a.m.

1 stop14h 21m

C$ 738

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Sun 8/11

5:07 a.m.-10:05 p.m.

1 stop19h 58m

Mexico City Benito Juarez

Sat 14/11

1:20 a.m.-5:46 a.m.

1 stop25h 26m

C$ 738

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Sat 7/11

5:07 a.m.-10:05 p.m.

1 stop19h 58m

Mexico City Benito Juarez

Sat 14/11

1:20 a.m.-11:36 p.m.

1 stop19h 16m

C$ 738

SantiagoMexico City

SCL Santiago Arturo Merino Benitez - MEX Mexico City Benito Juarez

SCLMEX

Santiago Arturo Merino Benitez

Sun 27/9

1:06 a.m.-7:05 p.m.

1 stop20h 59m

Mexico City Benito Juarez

Thu 1/10

3:30 p.m.-11:39 p.m.

1 stop29h 09m

C$ 738

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/9

Showing 1-10 of 17 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santiago with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Mexico City

How far ahead should I book a flight from Santiago to Mexico City?

To ensure you get the cheapest price possible for a flight from Santiago to Mexico City, you should look to book at least 82 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Santiago to Mexico City?

Currently, March is the cheapest month in which you can book a flight from Santiago to Mexico City (average of C$ 795). Flying from Santiago to Mexico City in June is currently the most expensive (average of C$ 1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to MEX?

When flying from Santiago to Mexico City, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Santiago to Mexico City?

Airfare is below average for this route at the moment.

Santiago to Mexico City flights typically cost between C$ 770 and C$ 1,039 in September.
The cheapest round-trip price found within the last 5 days was C$ 738 on Copa Airlines (27 Sep-21 Oct).

Related info for your journey

  • How popular is this Santiago to Mexico City flight route?

    Flights from Santiago Arturo Merino Benitez to Mexico City Benito Juarez have been viewed 2 times in the past calendar month.

  • How long is the flight from Santiago to Mexico City?

    For as low as C$ 738, Copa Airlines can have you in Mexico City from Santiago in 21h 53m. Airlines will cover a distance of 6592 km.

  • Can I find deals for flights from Santiago to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santiago to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Mexico City.

  • Can I find deals for business class flights from Santiago to Mexico City?

    Yes. Cheapflights offers flight deals from Santiago to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Mexico City?

    Currently, March is the cheapest month in which you can book a flight from Santiago to Mexico City (average of C$ 795). Flying from Santiago to Mexico City in June is currently the most expensive (average of C$ 1,058). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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