Find flights
Deals
When to book
Airlines
FAQs

Cheap flights from Panama City to Madrid, Spain from C$ 595

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 21/9. Fares are subject to change and may not be available on all flights or dates of travel.
PTY — MAD
17 Jun — 24 Jun1
1 adult

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Madrid Barajas are usually found in March or February, booked 58 days in advance, depart on a Tuesday or Monday and return on a Monday

Cheap flight deals from Panama City to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 12 June 2025.

Round-trip from

C$ 978

One-way from

C$ 595

Popular in

July

Cheapest in

March

Average price

C$ 1,077
KLM
  • KLM
  • 5/7-26/9
  • 2 total stops
  • 51h 10m total
  • Panama City to Madrid
Search Deals
Turkish Airlines
  • Turkish Airlines
  • 21/9
  • 1 total stop
  • 32h 40m total
  • Panama City to Madrid
Search Deals
Highest demand for flights based on searches. 9% potential increase in price (C$ 143 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease (C$ 22 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2025
Search Deals

Find flight deals from Panama City to Madrid

Cheapest flights from Panama City to Madrid
Explore the most affordable flight options available from Panama City to Madrid. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 12 June 2025.

Sat 5/77:55 p.m.PTY - MAD
1 stop16h 25mMultiple Airlines
Fri 26/91:05 p.m.MAD - PTY
1 stop34h 45mMultiple Airlines
Deal found 11/6C$ 978
Sun 12/108:25 p.m.PTY - MAD
Nonstop9h 50mAir Europa
Mon 27/103:10 p.m.MAD - PTY
Nonstop10h 35mAir Europa
Deal found 11/6C$ 990
Wed 17/99:55 p.m.PTY - MAD
1 stop29h 30mTurkish Airlines
Tue 7/1012:00 p.m.MAD - PTY
1 stop39h 00mTurkish Airlines
Deal found 12/6C$ 1,012
Tue 4/116:45 p.m.PTY - MAD
1 stop15h 20mKLM
Tue 18/118:35 p.m.MAD - PTY
1 stop25h 50mKLM
Deal found 11/6C$ 1,025
Thu 30/103:19 a.m.PTY - MAD
1 stop13h 16mAvianca
Wed 5/1110:55 a.m.MAD - PTY
1 stop16h 05mAvianca
Deal found 11/6C$ 1,092
Sun 5/109:45 a.m.PTY - MAD
1 stop16h 15mUnited Airlines
Wed 15/1011:15 a.m.MAD - PTY
2 stops38h 22mUnited Airlines
Deal found 12/6C$ 1,155

Cheapflights Fare Finder

Customize your flight search to find flights from Panama City to Madrid that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 12 June 2025.
Use the filters below to find and compare flights from Panama City to Madrid that are best for you.

Fly from

Panama City

Fly to

Madrid

Route

Depart

Return

Price

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sat 5/7

7:55 p.m.-7:20 p.m.

1 stop16h 25m

Madrid Barajas

Fri 26/9

1:05 p.m.-4:50 p.m.

1 stop34h 45m

C$ 978

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 12/10

8:25 p.m.-1:15 p.m.

Nonstop9h 50m

Madrid Barajas

Mon 27/10

3:10 p.m.-7:45 p.m.

Nonstop10h 35m

C$ 990

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Wed 17/9

9:55 p.m.-10:25 a.m.

1 stop29h 30m

Madrid Barajas

Tue 7/10

12:00 p.m.-8:00 p.m.

1 stop39h 00m

C$ 1,012

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 4/11

6:45 p.m.-4:05 p.m.

1 stop15h 20m

Madrid Barajas

Tue 18/11

8:35 p.m.-4:25 p.m.

1 stop25h 50m

C$ 1,025

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Thu 30/10

3:19 a.m.-10:35 p.m.

1 stop13h 16m

Madrid Barajas

Wed 5/11

10:55 a.m.-9:00 p.m.

1 stop16h 05m

C$ 1,092

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 5/10

9:45 a.m.-9:00 a.m.

1 stop16h 15m

Madrid Barajas

Wed 15/10

11:15 a.m.-6:37 p.m.

2 stops38h 22m

C$ 1,155

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Sun 21/9

9:55 p.m.-1:35 p.m.

1 stop32h 40m

C$ 595

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Mon 13/10

1:30 p.m.-2:05 p.m.

2 stops17h 35m

C$ 658

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Tue 8/7

6:50 p.m.-12:05 p.m.

1 stop34h 15m

C$ 693

Panama CityMadrid

PTY - MAD

PTYMAD

Panama City Tocumen Intl

Thu 3/7

8:25 p.m.-1:15 p.m.

Nonstop9h 50m

C$ 721

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/6

Showing 1-10 of 13 results
1
2

Best time to book a flight from Panama City to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Madrid

How far ahead should I book a flight from Panama City to Madrid?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Madrid. Price data was last updated on 9 June 2025.

The best time to book flights from Panama City to Madrid is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Madrid?

Currently, November is the cheapest month in which you can book a flight from Panama City to Madrid (average of C$ 658). Flying from Panama City to Madrid in December is currently the most expensive (average of C$ 951). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MAD?

Find hourly flight availability from Panama City to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 12 June 2025.

Unlike at noon, when flights are generally more expensive, you can save up to 11% on flights from Panama City to Madrid by exploring options for tickets in the morning.

Weekly flight availability from Panama City to Madrid

Explore weekly flight availability from Panama City to Madrid. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 12 June 2025.

The most flights from PTY to MAD are scheduled on a Saturday (9 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (3 on average).

Rainfall in Madrid by month

Plan your trip to Madrid by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Madrid ranges from 10.0 - 60.0 mm per month. November is typically the wettest month, when rainfall can reach 60.0 mm. July is typically the driest time to visit Madrid when rainfall is around 10.0 mm.

Temperature in Madrid by month

Plan your trip to Madrid by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Madrid, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 25.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 5.0 C).

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated 12 June 2025.
To help decide which airline to fly from Panama City to Madrid, see what other customers have to say about KLM, United Airlines and Turkish Airlines. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,358 reviews
Check prices

Food

7.2

Boarding

7.8

Entertainment

7.1

Overall

7.8

Comfort

7.7

Crew

8.4

Reviews

1 / 20
8.0
Excellent

Allan,Jun 2025

YYZ - AMS

I always enjoy flying KLM. Service is attentive, friendly and professional. The seat, when fully reclined is a little hard; some kind of mattress or topper would be helpful here. The dinner was really not very good …. “Meatless meatballs” tasted quite peculiar. Breakfast which consisted of an egg white omelette in flour tortilla was also rather tasteless.
KLM
7.8
Good
1,358 reviews
KLM
7.8
Good
1,358 reviews
Check prices

Food

7.2

Boarding

7.8

Entertainment

7.1

Overall

7.8

Comfort

7.7

Crew

8.4

Reviews

1 / 20
8.0
Excellent

Allan,Jun 2025

YYZ - AMS

I always enjoy flying KLM. Service is attentive, friendly and professional. The seat, when fully reclined is a little hard; some kind of mattress or topper would be helpful here. The dinner was really not very good …. “Meatless meatballs” tasted quite peculiar. Breakfast which consisted of an egg white omelette in flour tortilla was also rather tasteless.
United Airlines
7.4
Good
8,790 reviews
KLM
7.8
Good
1,358 reviews
Check prices

Food

7.2

Boarding

7.8

Entertainment

7.1

Overall

7.8

Comfort

7.7

Crew

8.4

Reviews

1 / 20
8.0
Excellent

Allan,Jun 2025

YYZ - AMS

I always enjoy flying KLM. Service is attentive, friendly and professional. The seat, when fully reclined is a little hard; some kind of mattress or topper would be helpful here. The dinner was really not very good …. “Meatless meatballs” tasted quite peculiar. Breakfast which consisted of an egg white omelette in flour tortilla was also rather tasteless.
Turkish Airlines
7.3
Good
3,848 reviews
KLM
7.8
Good
1,358 reviews
Check prices

Food

7.2

Boarding

7.8

Entertainment

7.1

Overall

7.8

Comfort

7.7

Crew

8.4

Reviews

1 / 20
8.0
Excellent

Allan,Jun 2025

YYZ - AMS

I always enjoy flying KLM. Service is attentive, friendly and professional. The seat, when fully reclined is a little hard; some kind of mattress or topper would be helpful here. The dinner was really not very good …. “Meatless meatballs” tasted quite peculiar. Breakfast which consisted of an egg white omelette in flour tortilla was also rather tasteless.
Iberia
7.0
Good
2,776 reviews
KLM
7.8
Good
1,358 reviews
Check prices

Food

7.2

Boarding

7.8

Entertainment

7.1

Overall

7.8

Comfort

7.7

Crew

8.4

Reviews

1 / 20
8.0
Excellent

Allan,Jun 2025

YYZ - AMS

I always enjoy flying KLM. Service is attentive, friendly and professional. The seat, when fully reclined is a little hard; some kind of mattress or topper would be helpful here. The dinner was really not very good …. “Meatless meatballs” tasted quite peculiar. Breakfast which consisted of an egg white omelette in flour tortilla was also rather tasteless.
Air Europa
6.9
Okay
529 reviews
KLM
7.8
Good
1,358 reviews
Check prices

Food

7.2

Boarding

7.8

Entertainment

7.1

Overall

7.8

Comfort

7.7

Crew

8.4

Reviews

1 / 20
8.0
Excellent

Allan,Jun 2025

YYZ - AMS

I always enjoy flying KLM. Service is attentive, friendly and professional. The seat, when fully reclined is a little hard; some kind of mattress or topper would be helpful here. The dinner was really not very good …. “Meatless meatballs” tasted quite peculiar. Breakfast which consisted of an egg white omelette in flour tortilla was also rather tasteless.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Madrid?

    To fly from Panama City to Madrid, you need to book a flight from Tocumen Intl (PTY) to Barajas (MAD). Nonstop flights to Madrid Barajas from Panama City Tocumen Intl take 9h 50m on average. When it comes time to book airfare, you have a few options: there are 4 outbound flights from Tocumen Intl to Barajas offered by 1 airline.

  • How popular is this Panama City to Madrid flight route?

    This flight path from Panama City Tocumen Intl to Madrid Barajas was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Panama City to Madrid round-trip?

    Cheapflights users have booked flights from Panama City to Madrid round-trip from C$ 990. Other airlines that can offer you cheap pricing are Turkish Airlines, from C$ 1,012, and KLM, from C$ 1,025. Air Europa is currently priced 6% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City to Madrid one-way?

    For one-way options, check prices for Turkish Airlines. According to our data, you can fly for as low as C$ 595. Users have also found prices from C$ 658 and C$ 693 on Avianca and KLM, respectively.

  • What are the most reliable airlines from Panama City to Madrid?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Panama City to Madrid on time: Air Europa (88%), Etihad Airways (88%), China Eastern (88%).

  • Can I find deals for flights from Panama City to Madrid that include hotel bookings?

    Yes. In addition to deals on Panama City to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Madrid.

  • Can I find deals for business class flights from Panama City to Madrid?

    Yes. Cheapflights offers flight deals from Panama City to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Madrid (average of C$ 658). Flying from Panama City to Madrid in December is currently the most expensive (average of C$ 951). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Panama City to Madrid

Discover the top airline that operate flights from Panama City to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 12 June 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapestC$ 1,035AverageC$ 2,630FlexibilityNo cancel feeOn-time83%
Search Air Europa flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Panama City to Madrid?

900+ travel sites are searched through when a user searches for a flight using Cheapflights. From the search interface, users can use filters to choose airlines, airports, flight times, cabin classes and more to their preference. Book your flight to Madrid from Panama City today with Cheapflights!

Why should you use Cheapflights to find cheap flight tickets from Panama City to Madrid?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City to Madrid for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City to Madrid with no change fees?

Need flexible booking options for your flight to Madrid from Panama City? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Panama City to Madrid become cheaper?

Yes, Cheapflights offers price alerts on Panama City to Madrid flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.