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Cheap flights from Panama City to Madrid, Spain

PTY — MAD
4 Aug — 11 Aug1
1 adult

Cheapflights Tip: The best prices from Panama City Tocumen Intl to Madrid Barajas are usually found in March or February, booked 58 days in advance, depart on a Tuesday or Monday and return on a Monday

Cheap flight deals from Panama City to Madrid

Discover tips and strategies to find the most affordable flight options for your journey from Panama City (PTY) to Madrid (MAD). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 30 July 2025.

Round-trip from

C$ 1,025

One-way from

C$ 615

Popular in

July

Cheapest in

March

Average price

C$ 1,222
Air France
  • Air France
  • 15/10-26/10
  • 2 total stops
  • 51h 55m total
  • Panama City to Madrid
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Turkish Airlines
  • Turkish Airlines
  • 1/10
  • 1 total stop
  • 35h 55m total
  • Panama City to Madrid
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Highest demand for flights based on searches. 8% potential increase in price (C$ 138 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease (C$ 21 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Best time to book a flight from Panama City to Madrid

Have a flexible travel schedule? Discover the best time to fly to Madrid from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Madrid

How far ahead should I book a flight from Panama City to Madrid?

Use this chart to determine the optimal time to book a round-trip flight from Panama City to Madrid. Price data was last updated on 25 July 2025.

The best time to book flights from Panama City to Madrid is 58 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Panama City to Madrid?

Currently, November is the cheapest month in which you can book a flight from Panama City to Madrid (average of C$ 658). Flying from Panama City to Madrid in December is currently the most expensive (average of C$ 951). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from PTY to MAD?

Find hourly flight availability from Panama City to Madrid. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 30 July 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City to Madrid as you normally would.

Weekly flight availability from Panama City to Madrid

Explore weekly flight availability from Panama City to Madrid. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated 30 July 2025.

The most flights from PTY to MAD are scheduled on a Monday (10 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (5 on average).

Reviews of airlines servicing Madrid

Get insights into the airlines that provide service to Madrid. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Madrid. Reviews last updated 30 July 2025.
See what other customers who have flown with KLM,Copa Airlines, andUnited Airlines from Panama City to Madrid have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
KLM
7.8
Good
1,383 reviews
Check prices

Food

7.3

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
KLM
7.8
Good
1,383 reviews
KLM
7.8
Good
1,383 reviews
Check prices

Food

7.3

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Copa Airlines
7.5
Good
1,493 reviews
KLM
7.8
Good
1,383 reviews
Check prices

Food

7.3

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
United Airlines
7.4
Good
8,896 reviews
KLM
7.8
Good
1,383 reviews
Check prices

Food

7.3

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Turkish Airlines
7.3
Good
3,928 reviews
KLM
7.8
Good
1,383 reviews
Check prices

Food

7.3

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.
Air Europa
7.0
Good
543 reviews
KLM
7.8
Good
1,383 reviews
Check prices

Food

7.3

Comfort

7.7

Boarding

7.8

Crew

8.4

Entertainment

7.1

Overall

7.8

Reviews

1 / 20
4.0
Okay

Anonymous,Jun 2025

AMS - BOS

A two and half hour delay caused havoc with all connections. Otherwise on board service was great.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Madrid. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Panama City to Madrid?

    To fly from Panama City to Madrid, you need to book a flight from Tocumen Intl (PTY) to Barajas (MAD). Nonstop flights to Madrid Barajas from Panama City Tocumen Intl take 9h 50m on average. When it comes time to book airfare, you have a few options: there are 7 outbound flights from Tocumen Intl to Barajas offered by 1 airline.

  • How popular is this Panama City to Madrid flight route?

    This flight path from Panama City Tocumen Intl to Madrid Barajas was viewed by 7 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • What are the cheapest airlines flying from Panama City to Madrid round-trip?

    Cheapflights users have booked flights from Panama City to Madrid round-trip from C$ 1,036. Other airlines that can offer you cheap pricing are Air Europa, from C$ 1,044, and KLM, from C$ 1,059. Turkish Airlines is currently priced 2% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Panama City to Madrid one-way?

    For one-way options, check prices for Turkish Airlines. According to our data, you can fly for as low as C$ 615. Users have also found prices from C$ 727 and C$ 832 on Air Europa and Copa Airlines, respectively.

  • What are the most reliable airlines from Panama City to Madrid?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Panama City to Madrid on time: Hainan Airlines (100%), Air Europa (86%), Etihad Airways (86%).

  • Can I find deals for flights from Panama City to Madrid that include hotel bookings?

    Yes. In addition to deals on Panama City to Madrid flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Madrid?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Madrid.

  • Can I find deals for business class flights from Panama City to Madrid?

    Yes. Cheapflights offers flight deals from Panama City to Madrid by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City to Madrid?

    Currently, November is the cheapest month in which you can book a flight from Panama City to Madrid (average of C$ 658). Flying from Panama City to Madrid in December is currently the most expensive (average of C$ 951). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Panama City to Madrid

Discover the top airline that operate flights from Panama City to Madrid. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 30 July 2025.
AirlineCheapestAverageFlexibilityOn-time
Air EuropaCheapestC$ 1,448AverageC$ 2,654FlexibilityNo cancel feeOn-time83%
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Fly with Cheapflights

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How does Cheapflights help users find flights from Panama City to Madrid?

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Why should you use Cheapflights to find cheap flight tickets from Panama City to Madrid?

Millions of users choose and trust Cheapflights to book the best flight deals from Panama City to Madrid for free. We help you search and compare prices from hundreds of airlines for the right flight just for you.

Can Cheapflights find flights from Panama City to Madrid with no change fees?

Need flexible booking options for your flight to Madrid from Panama City? Don’t worry, Cheapflights have you covered. Use our search filter to only show flights with no change fees.

Can Cheapflights notify me if prices for flights from Panama City to Madrid become cheaper?

Yes, Cheapflights offers price alerts on Panama City to Madrid flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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