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Cheap flights from Buffalo to St. Louis from C$ 267

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 25/5. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
24 Apr — 1 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Buffalo to St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 25 March 2026.

Tue 21/46:55 p.m.
BUF
-
STL
1 stop4h 15m
Southwest
Tue 28/45:35 a.m.
STL
-
BUF
1 stop3h 45m
Southwest
Deal found 23/3C$ 334
Tue 14/411:00 a.m.
BUF
-
STL
1 stop5h 15m
Southwest
Sat 18/410:55 a.m.
STL
-
BUF
2 stops6h 05m
Southwest
Deal found 24/3C$ 363
Sat 18/43:01 p.m.
BUF
-
STL
1 stop6h 08m
American Airlines
Mon 20/48:54 a.m.
STL
-
BUF
1 stop4h 27m
American Airlines
Deal found 23/3C$ 364
Mon 13/44:00 p.m.
BUF
-
STL
2 stops7h 45m
Southwest
Wed 22/45:35 a.m.
STL
-
BUF
1 stop3h 45m
Southwest
Deal found 23/3C$ 378
Thu 7/58:00 p.m.
BUF
-
STL
1 stop3h 45m
Southwest
Sat 9/510:55 a.m.
STL
-
BUF
2 stops6h 05m
Southwest
Deal found 24/3C$ 419
Fri 17/412:08 p.m.
BUF
-
STL
1 stop19h 42m
Frontier
Tue 21/44:59 p.m.
STL
-
BUF
2 stops18h 43m
Frontier
Deal found 23/3C$ 422
Wed 10/611:00 a.m.
BUF
-
STL
2 stops7h 30m
Southwest
Sun 14/65:50 a.m.
STL
-
BUF
1 stop3h 30m
Southwest
Deal found 23/3C$ 426
Sat 18/42:00 p.m.
BUF
-
STL
2 stops6h 10m
Southwest
Mon 20/47:45 p.m.
STL
-
BUF
1 stop11h 05m
Southwest
Deal found 23/3C$ 437
Mon 1/68:00 p.m.
BUF
-
STL
1 stop3h 45m
Southwest
Fri 5/65:00 a.m.
STL
-
BUF
1 stop5h 35m
Southwest
Deal found 22/3C$ 451

Find flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 25 March 2026.

Round-trip from

C$ 304

One-way from

C$ 267

Popular in

March

Cheapest in

September

Average price

C$ 791
Southwest
  • Southwest
  • 14/4-21/4
  • 2 total stops
  • 10h 25m total
  • Buffalo to St. Louis
Search Deals
United Airlines
  • United Airlines
  • 25/5
  • 1 total stop
  • 4h 24m total
  • Buffalo to St. Louis
Search Deals
Highest demand for flights based on searches. 21% potential increase in price (C$ 193 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (C$ 37 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 25 March 2026.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 14/4

9:45 a.m.-6:00 p.m.

2 stops9h 15m

Lambert-St Louis

Sat 18/4

6:10 a.m.-4:35 p.m.

2 stops9h 25m

C$ 370
Quickest round-trip

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 21/4

9:25 a.m.-12:50 p.m.

1 stop4h 25m

Lambert-St Louis

Tue 28/4

5:35 a.m.-10:20 a.m.

1 stop3h 45m

C$ 408

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 7/5

8:00 p.m.-10:45 p.m.

1 stop3h 45m

Lambert-St Louis

Sat 9/5

10:55 a.m.-6:00 p.m.

2 stops6h 05m

C$ 419

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 18/4

2:00 p.m.-7:10 p.m.

2 stops6h 10m

Lambert-St Louis

Mon 20/4

7:45 p.m.-7:50 a.m.

1 stop11h 05m

C$ 437

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 4/5

7:02 p.m.-11:57 p.m.

1 stop5h 55m

Lambert-St Louis

Tue 5/5

11:15 a.m.-4:54 p.m.

1 stop4h 39m

C$ 521

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 12/6

7:27 p.m.-11:56 p.m.

1 stop5h 29m

Lambert-St Louis

Wed 17/6

1:59 p.m.-7:17 p.m.

1 stop4h 18m

C$ 536
Cheapest one-way
Quickest one-way

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 25/5

5:52 p.m.-9:16 p.m.

1 stop4h 24m

C$ 267

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 5/4

8:25 a.m.-3:10 p.m.

2 stops7h 45m

C$ 342

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 27/3

5:55 p.m.-12:05 a.m.

2 stops7h 10m

C$ 418

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 15/5

7:50 p.m.-10:48 a.m.

2 stops15h 58m

C$ 552

Flights are sorted by cheapest round-trip flights first.

Deals found on 22/3

Showing 1-10 of 11 resultsSorted by cheapest first
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Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 154). Flying from Buffalo to St. Louis in February is currently the most expensive (average of C$ 429). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to St. Louis?

    For as low as C$ 370, Southwest can have you in St. Louis from Buffalo in 9h 15m. The distance between Buffalo and St. Louis is about 1081 km.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 154). Flying from Buffalo to St. Louis in February is currently the most expensive (average of C$ 429). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Chesterfield

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Alternative routes for Buffalo to St. Louis

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Buffalo to Kansas City flights

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How does Cheapflights help users find flights from Buffalo to St. Louis?

Cheapflights makes it easy to find Buffalo to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

Yes! Start tracking prices for Buffalo to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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