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Cheap flights from Buffalo to St. Louis from C$ 181

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 13/4. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
28 Mar — 4 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Buffalo to St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 February 2026.

Tue 14/45:57 p.m.
BUF
-
STL
1 stop4h 11m
United Airlines
Wed 15/49:10 a.m.
STL
-
BUF
1 stop7h 06m
United Airlines
Deal found 25/2C$ 324
Mon 13/44:59 p.m.
BUF
-
STL
1 stop7h 37m
Delta
Wed 15/46:48 a.m.
STL
-
BUF
1 stop3h 51m
Delta
Deal found 25/2C$ 342
Tue 14/44:00 p.m.
BUF
-
STL
2 stops7h 10m
Southwest
Wed 15/45:35 a.m.
STL
-
BUF
1 stop3h 45m
Southwest
Deal found 25/2C$ 345
Sun 5/46:00 a.m.
BUF
-
STL
1 stop6h 09m
Delta
Mon 13/45:59 p.m.
STL
-
BUF
1 stop3h 40m
Delta
Deal found 24/2C$ 426
Mon 16/35:59 p.m.
BUF
-
STL
1 stop6h 45m
American Airlines
Fri 20/36:40 p.m.
STL
-
BUF
1 stop4h 00m
American Airlines
Deal found 23/2C$ 427
Sat 4/46:08 p.m.
BUF
-
STL
1 stop6h 50m
Delta
Tue 14/49:59 a.m.
STL
-
BUF
1 stop4h 54m
Delta
Deal found 24/2C$ 446
Wed 23/97:03 p.m.
BUF
-
STL
1 stop5h 24m
United Airlines
Mon 28/91:27 p.m.
STL
-
BUF
1 stop6h 04m
United Airlines
Deal found 23/2C$ 468
Mon 13/44:00 p.m.
BUF
-
STL
2 stops8h 15m
Southwest
Wed 15/47:35 a.m.
STL
-
BUF
2 stops6h 00m
Southwest
Deal found 25/2C$ 474
Mon 13/44:00 p.m.
BUF
-
STL
2 stops8h 15m
Southwest
Fri 17/42:25 p.m.
STL
-
BUF
2 stops7h 55m
Southwest
Deal found 25/2C$ 476
Fri 13/37:38 p.m.
BUF
-
STL
1 stop5h 20m
Delta
Tue 17/35:21 p.m.
STL
-
BUF
1 stop5h 25m
Delta
Deal found 24/2C$ 482

Find flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 26 February 2026.

Round-trip from

C$ 324

One-way from

C$ 181

Popular in

February

Cheapest in

September

Average price

C$ 669
United Airlines
  • United Airlines
  • 14/4-15/4
  • 2 total stops
  • 11h 17m total
  • Buffalo to St. Louis
Search Deals
Delta
  • Delta
  • 13/4
  • 1 total stop
  • 7h 37m total
  • Buffalo to St. Louis
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (C$ 101 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (C$ 23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in February 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 26 February 2026.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 5/4

6:00 a.m.-11:09 a.m.

1 stop6h 09m

Lambert-St Louis

Mon 13/4

5:59 p.m.-10:39 p.m.

1 stop3h 40m

C$ 426

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 13/3

7:38 p.m.-11:58 p.m.

1 stop5h 20m

Lambert-St Louis

Tue 17/3

5:21 p.m.-11:46 p.m.

1 stop5h 25m

C$ 482

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 13/3

5:29 p.m.-9:42 p.m.

1 stop5h 13m

Lambert-St Louis

Tue 17/3

6:25 a.m.-2:14 p.m.

2 stops6h 49m

C$ 545

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 12/3

7:00 a.m.-10:36 a.m.

1 stop4h 36m

Lambert-St Louis

Tue 17/3

10:00 a.m.-6:42 p.m.

2 stops7h 42m

C$ 546

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 16/3

7:56 p.m.-4:32 p.m.

2 stops21h 36m

Lambert-St Louis

Fri 20/3

6:10 a.m.-2:19 p.m.

1 stop7h 09m

C$ 554

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 12/7

6:10 a.m.-11:05 a.m.

1 stop5h 55m

Lambert-St Louis

Sat 18/7

5:05 a.m.-5:45 p.m.

1 stop11h 40m

C$ 564

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 10/3

6:00 a.m.-11:09 a.m.

1 stop6h 09m

Lambert-St Louis

Sat 14/3

10:07 a.m.-4:56 p.m.

1 stop5h 49m

C$ 612

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 10/3

10:45 a.m.-3:30 p.m.

1 stop5h 45m

Lambert-St Louis

Sat 14/3

7:40 p.m.-7:50 a.m.

1 stop11h 10m

C$ 619

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 5/4

6:09 a.m.-12:22 p.m.

2 stops7h 13m

Lambert-St Louis

Sat 11/4

7:45 a.m.-6:14 p.m.

2 stops9h 29m

C$ 632

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 13/4

4:00 p.m.-11:15 p.m.

2 stops8h 15m

C$ 215

Flights are sorted by cheapest round-trip flights first.

Deals found on 25/2

Showing 1-10 of 16 resultsSorted by cheapest first
1
2

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 153). Flying from Buffalo to St. Louis in February is currently the most expensive (average of C$ 428). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated 26 February 2026.
Check out reviews from past customers who have flown with Southwest from Buffalo to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,299 reviews
Check prices

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.
Southwest
8.0
Very good
4,299 reviews
Southwest
8.0
Very good
4,299 reviews
Check prices

Boarding

8.1

Food

7.0

Entertainment

7.5

Crew

8.6

Overall

8.0

Comfort

8.0

Reviews

1 / 20
6.0
Good

Scott,Feb 2026

HOU - FLL

Delayed by 45 minutes leaving Houston, making a 3.5 hour layover that much longer.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to St. Louis?

    For as low as C$ 545, Delta can have you in St. Louis from Buffalo in 5h 13m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Buffalo to St. Louis round-trip?

    Currently priced at C$ 351, Southwest will fly you from Buffalo to St. Louis and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. You may be able to fly from Buffalo to St. Louis for 28% less than the average price by searching for this airline.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 153). Flying from Buffalo to St. Louis in February is currently the most expensive (average of C$ 428). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Chesterfield

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Alternative routes for Buffalo to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Buffalo to Kansas City flights

Top airline flying from Buffalo to St. Louis

Discover the top airline that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 26 February 2026.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapestC$ 351AverageC$ 611FlexibilityNo cancel feeOn-time63%
Search Southwest flights

Fly with Cheapflights

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How does Cheapflights help users find flights from Buffalo to St. Louis?

Cheapflights makes it easy to find Buffalo to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

Yes! Start tracking prices for Buffalo to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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