Find flights
When to book
Airlines
FAQs

Cheap flights from Buffalo to St. Louis from C$ 153

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 20/1. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
26 Jan — 2 Feb1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Buffalo to St. Louis

Enter your travel dates to find the best prices.

Best flights from Buffalo to St. Louis
Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 27 December 2025.

Sun 18/16:03 a.m.BUF - STL
1 stop4h 36mDelta
Tue 20/110:19 a.m.STL - BUF
1 stop5h 40mDelta
Deal found 25/12C$ 305
Mon 26/16:20 p.m.BUF - STL
1 stop6h 39mUnited Airlines
Wed 28/13:11 p.m.STL - BUF
1 stop4h 18mUnited Airlines
Deal found 27/12C$ 386
Sun 22/22:19 p.m.BUF - STL
2 stops34h 40mFrontier
Fri 27/28:22 p.m.STL - BUF
1 stop13h 43mFrontier
Deal found 27/12C$ 413
Mon 26/112:20 p.m.BUF - STL
2 stops7h 25mSouthwest
Wed 28/18:20 a.m.STL - BUF
2 stops7h 45mSouthwest
Deal found 27/12C$ 463
Tue 3/25:23 p.m.BUF - STL
1 stop6h 35mUnited Airlines
Wed 4/211:20 a.m.STL - BUF
2 stops10h 11mUnited Airlines
Deal found 24/12C$ 454
Tue 5/512:06 p.m.BUF - STL
1 stop4h 32mDelta
Thu 7/57:20 a.m.STL - BUF
1 stop7h 39mDelta
Deal found 26/12C$ 468
Tue 5/53:10 p.m.BUF - STL
2 stops7h 50mSouthwest
Thu 7/55:00 a.m.STL - BUF
1 stop6h 00mSouthwest
Deal found 26/12C$ 474

Find flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 27 December 2025.

Round-trip from

C$ 305

One-way from

C$ 153

Popular in

March

Cheapest in

September

Average price

C$ 476
Delta
  • Delta
  • 18/1-20/1
  • 2 total stops
  • 10h 16m total
  • Buffalo to St. Louis
Search Deals
Delta
  • Delta
  • 20/1
  • 1 total stop
  • 3h 59m total
  • Buffalo to St. Louis
Search Deals
Highest demand for flights based on searches. 5% potential increase in price (C$ 40 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease (C$ 6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 27 December 2025.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Buffalo

Fly to

St. Louis

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 18/1

6:03 a.m.-9:39 a.m.

1 stop4h 36m

Lambert-St Louis

Tue 20/1

10:19 a.m.-4:59 p.m.

1 stop5h 40m

C$ 305

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 26/1

6:20 p.m.-11:59 p.m.

1 stop6h 39m

Lambert-St Louis

Wed 28/1

3:11 p.m.-8:29 p.m.

1 stop4h 18m

C$ 386

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 22/2

2:19 p.m.-11:59 p.m.

2 stops34h 40m

Lambert-St Louis

Fri 27/2

8:22 p.m.-11:05 a.m.

1 stop13h 43m

C$ 413

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 3/2

5:23 p.m.-10:58 p.m.

1 stop6h 35m

Lambert-St Louis

Wed 4/2

11:20 a.m.-10:31 p.m.

2 stops10h 11m

C$ 454

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 26/1

12:20 p.m.-6:45 p.m.

2 stops7h 25m

Lambert-St Louis

Wed 28/1

8:20 a.m.-5:05 p.m.

2 stops7h 45m

C$ 463

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 5/5

12:06 p.m.-3:38 p.m.

1 stop4h 32m

Lambert-St Louis

Thu 7/5

7:20 a.m.-3:59 p.m.

1 stop7h 39m

C$ 468

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 5/5

3:10 p.m.-10:00 p.m.

2 stops7h 50m

Lambert-St Louis

Thu 7/5

5:00 a.m.-12:00 p.m.

1 stop6h 00m

C$ 474

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 20/1

5:44 p.m.-8:43 p.m.

1 stop3h 59m

C$ 153

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 24/1

5:44 p.m.-8:43 p.m.

1 stop3h 59m

C$ 176

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 21/1

10:37 a.m.-4:39 p.m.

1 stop7h 02m

C$ 176

Flights are sorted by cheapest round-trip flights first.

Deals found on 24/12

Showing 1-10 of 14 results
1
2

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 153). Flying from Buffalo to St. Louis in February is currently the most expensive (average of C$ 421). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated 27 December 2025.
Check out reviews from past customers who have flown with Southwest from Buffalo to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,256 reviews
Check prices

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am
Southwest
8.0
Very good
4,256 reviews
Southwest
8.0
Very good
4,256 reviews
Check prices

Boarding

8.1

Comfort

8.0

Food

7.0

Crew

8.6

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
2.0
Mediocre

Thomas,Dec 2025

SEA - DEN

Plane two hours late in leaving 1:00 pm west coat time got home next day at 2:45am most car rental places are closed and don’t open till 5am

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to St. Louis?

    For as low as C$ 305, Delta can have you in St. Louis from Buffalo in 4h 36m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Buffalo to St. Louis round-trip?

    Currently priced at C$ 350, Southwest will fly you from Buffalo to St. Louis and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. You may be able to fly from Buffalo to St. Louis for 27% less than the average price by searching for this airline.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 153). Flying from Buffalo to St. Louis in February is currently the most expensive (average of C$ 421). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Chesterfield
St. Peters

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Buffalo to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Buffalo to Kansas City flights

Top airline flying from Buffalo to St. Louis

Discover the top airline that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 27 December 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapestC$ 350AverageC$ 576FlexibilityNo cancel feeOn-time63%
Search Southwest flights

Fly with Cheapflights

Find the best flight deals on Cheapflights, where travelers can enjoy low prices and a wide availability of flights to their desired destinations.

How does Cheapflights help users find flights from Buffalo to St. Louis?

Cheapflights makes it easy to find Buffalo to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

Yes! Start tracking prices for Buffalo to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.