How long is the flight from Buffalo to St. Louis?

For as low as C$ 379, Delta can have you in St. Louis from Buffalo in 6h 14m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.

In terms of precipitation, rainfall in St. Louis ranges from 56.0 - 119.0 mm per month. May is typically the wettest month, when rainfall can reach 119.0 mm. February is typically the driest time to visit St. Louis when rainfall is around 56.0 mm.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 0.0 C).

What is the cheapest time of day to fly from BUF to STL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to St. Louis as you normally would.

Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Buffalo to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

Can I find deals for business class flights from Buffalo to St. Louis?

Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 268+ Cheap Flights from Buffalo to St. Louis

Cheap flight deals from Buffalo to St. Louis

Enter your travel dates to find the best prices.

Cheapest

Best

Last-minute

One-way

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3 November 2026.

Wed 2/1212:06 p.m. -

1 stop6h 14m

Sat 5/125:31 p.m. -

1 stop5h 33m

Deal found 29/10C$ 379

Tue 24/116:40 p.m. -

1 stop6h 05m

Tue 1/126:35 a.m. -

1 stop4h 30m

Deal found 30/10C$ 432

Wed 2/1212:06 p.m. -

1 stop6h 14m

Sun 6/126:32 a.m. -

1 stop3h 52m

Deal found 29/10C$ 444

Wed 2/1212:45 p.m. -

2 stops7h 40m

Sun 6/123:20 p.m. -

1 stop8h 45m

Deal found 29/10C$ 451

Thu 26/116:30 a.m. -

1 stop5h 02m

Sun 29/116:50 p.m. -

1 stop6h 57m

Deal found 2/11C$ 521

Wed 2/126:00 a.m. -

2 stops9h 41m

Sat 5/123:25 p.m. -

1 stop4h 31m

Deal found 29/10C$ 526

Sat 28/115:45 a.m. -

1 stop4h 35m

Sat 5/125:45 a.m. -

2 stops6h 45m

Deal found 29/10C$ 544

Tue 22/1212:40 p.m. -

1 stop5h 55m

Sun 27/125:30 a.m. -

1 stop3h 35m

Deal found 2/11C$ 563

Fri 20/117:20 a.m. -

1 stop3h 45m

Mon 23/114:40 p.m. -

2 stops6h 10m

Deal found 2/11C$ 579

Thu 3/1210:00 a.m. -

2 stops8h 05m

Sat 5/125:05 p.m. -

1 stop5h 29m

Deal found 29/10C$ 581

Find flight deals from Buffalo to St. Louis

Round-trip from	C$ 379
One-way from	C$ 268
Popular in	March
Cheapest in	December
Average price	C$ 537

Delta
2/12-5/12
2 total stops
11h 47m total
Buffalo to St. Louis

Search Deals

Southwest
20/12-31/12
1 total stop
6h 05m total
Buffalo to St. Louis

Search Deals

Highest demand for flights based on searches. 16% potential increase in price (C$ 161 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease (C$ 44 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in November 2026

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Sun 20/12

6:40 p.m.-11:45 p.m.

1 stop6h 05m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 268

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Sat 28/11

9:10 a.m.-1:23 p.m.

1 stop5h 13m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 306

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Thu 19/11

12:45 p.m.-7:25 p.m.

2 stops7h 40m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 369

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Wed 2/12

12:06 p.m.-5:20 p.m.

1 stop6h 14m

Lambert-St Louis

Sat 5/12

5:31 p.m.-12:04 a.m.

1 stop5h 33m

C$ 379

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Fri 27/11

8:05 a.m.-7:10 p.m.

2 stops12h 05m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 391

Quickest round-trip

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Mon 9/11

7:20 a.m.-10:05 a.m.

1 stop3h 45m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 481

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Wed 3/3

6:00 a.m.-12:32 p.m.

1 stop7h 32m

Lambert-St Louis

Sun 7/3

6:45 a.m.-11:44 a.m.

1 stop3h 59m

C$ 507

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Wed 2/12

6:00 a.m.-2:41 p.m.

2 stops9h 41m

Lambert-St Louis

Sat 5/12

3:25 p.m.-8:56 p.m.

1 stop4h 31m

C$ 526

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Wed 23/12

4:30 p.m.-8:45 p.m.

1 stop5h 15m

Lambert-St Louis

Sun 27/12

5:30 a.m.-10:05 a.m.

1 stop3h 35m

C$ 563

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Fri 20/11

7:20 a.m.-10:05 a.m.

1 stop3h 45m

Lambert-St Louis

Mon 23/11

4:40 p.m.-11:50 p.m.

2 stops6h 10m

C$ 579

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/11

Showing 1-10 of 17 resultsSorted by cheapest first

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.

BUF-STL

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 475). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 945). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to St. Louis?

Airfare is below average for this route at the moment.

Buffalo to St. Louis flights typically cost between C$ 458 and C$ 623 in December.
The cheapest round-trip price found within the last 5 days was C$ 379 on Delta (2 Dec-5 Dec).

Related info for your journey

How long is the flight from Buffalo to St. Louis?
For as low as C$ 379, Delta can have you in St. Louis from Buffalo in 6h 14m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.
Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?
Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Buffalo to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.
Can I find deals for business class flights from Buffalo to St. Louis?
Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Buffalo to St. Louis?
Currently, December is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 475). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 945). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

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Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

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Cheap flights from Buffalo to St. Louis from C$ 268

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 20/12. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. LouisExplore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3 November 2026.

Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3 November 2026.

Best flights from Buffalo to St. LouisDiscover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 3 November 2026.

Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 3 November 2026.

Last-minute flights from Buffalo to St. LouisDiscover last-minute flight deals from Buffalo to St. Louis. Data last updated 3 November 2026 and is based on user searches.

Discover last-minute flight deals from Buffalo to St. Louis. Data last updated 3 November 2026 and is based on user searches.

One-way flights from Buffalo to St. LouisSearch for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated 3 November 2026.

Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated 3 November 2026.

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Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.

Cheapflights Insights

What is the cheapest month to book a flight from Buffalo to St. Louis?

How much does it cost to fly round-trip from Buffalo to St. Louis?

Airfare is below average for this route at the moment.

Buffalo to St. Louis flights typically cost between C$ 458 and C$ 623 in December.The cheapest round-trip price found within the last 5 days was C$ 379 on Delta (2 Dec-5 Dec).

Related info for your journey

How long is the flight from Buffalo to St. Louis?

Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

How can I find direct flights from Buffalo to St. Louis?

Can I find deals for business class flights from Buffalo to St. Louis?

What is the cheapest month to book a flight from Buffalo to St. Louis?

Travelling to a place near St. Louis?

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Direct flights to Missouri

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Buffalo and St. Louis flights

Browse other Buffalo and St. Louis flight options. Last updated on 3 November 2026.

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Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

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Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 3 November 2026.

Best flights from Buffalo to St. Louis
Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 3 November 2026.

Last-minute flights from Buffalo to St. Louis
Discover last-minute flight deals from Buffalo to St. Louis. Data last updated 3 November 2026 and is based on user searches.

One-way flights from Buffalo to St. Louis
Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated 3 November 2026.

Buffalo to St. Louis flights typically cost between C$ 458 and C$ 623 in December.
The cheapest round-trip price found within the last 5 days was C$ 379 on Delta (2 Dec-5 Dec).