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Cheap flights from Buffalo to St. Louis from C$ 166

BUF — STL
21 Sep — 28 Sep1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Buffalo to St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to St. Louis

Mon 14/91:40 p.m. -
2 stops22h 52m
Mon 21/95:19 p.m. -
1 stop23h 30m
Deal found 17/8C$ 377
Tue 8/911:36 a.m. -
1 stop26h 34m
Thu 10/96:39 p.m. -
2 stops17h 16m
Deal found 20/8C$ 389
Mon 14/95:40 a.m. -
1 stop6h 55m
Mon 21/96:05 a.m. -
1 stop3h 40m
Deal found 17/8C$ 425
Sat 26/95:45 a.m. -
2 stops7h 50m
Tue 29/91:20 p.m. -
1 stop7h 35m
Deal found 20/8C$ 432
Fri 6/117:20 a.m. -
1 stop3h 45m
Mon 9/118:30 a.m. -
1 stop5h 45m
Deal found 19/8C$ 436
Wed 21/109:45 a.m. -
2 stops6h 15m
Tue 27/108:30 a.m. -
2 stops8h 50m
Deal found 22/8C$ 439
Tue 22/912:02 p.m. -
1 stop6h 08m
Fri 25/95:59 p.m. -
1 stop4h 54m
Deal found 17/8C$ 443
Fri 16/106:50 a.m. -
1 stop7h 55m
Mon 19/109:00 p.m. -
1 stop10h 25m
Deal found 21/8C$ 450
Tue 6/1012:35 p.m. -
2 stops7h 25m
Tue 13/108:30 a.m. -
2 stops5h 45m
Deal found 22/8C$ 464

Find flight deals from Buffalo to St. Louis

Round-trip from

C$ 377

One-way from

C$ 166

Popular in

March

Cheapest in

January

Average price

C$ 538
Frontier
  • Frontier
  • 14/9-21/9
  • 3 total stops
  • 46h 22m total
  • Buffalo to St. Louis
Search Deals
Frontier
  • Frontier
  • 4/10
  • 2 total stops
  • 25h 21m total
  • Buffalo to St. Louis
Search Deals
Highest demand for flights based on searches. 18% potential increase in price (C$ 182 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease (C$ 45 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Wed 16/9

6:20 a.m.-9:29 a.m.

1 stop4h 09m

Lambert-St Louis

Sat 19/9

4:10 p.m.-10:35 p.m.

1 stop5h 25m

C$ 425

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Mon 14/9

5:40 a.m.-11:35 a.m.

1 stop6h 55m

Lambert-St Louis

Mon 21/9

6:05 a.m.-10:45 a.m.

1 stop3h 40m

C$ 425

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Wed 23/9

3:53 p.m.-8:35 p.m.

1 stop5h 42m

Lambert-St Louis

Sat 26/9

4:10 p.m.-10:35 p.m.

1 stop5h 25m

C$ 425

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Wed 21/10

9:45 a.m.-3:00 p.m.

2 stops6h 15m

Lambert-St Louis

Tue 27/10

8:30 a.m.-6:20 p.m.

2 stops8h 50m

C$ 439

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Tue 6/10

4:00 p.m.-11:10 p.m.

1 stop8h 10m

Lambert-St Louis

Tue 13/10

8:30 a.m.-3:15 p.m.

2 stops5h 45m

C$ 457

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Fri 6/11

3:05 p.m.-9:00 p.m.

2 stops6h 55m

Lambert-St Louis

Mon 9/11

4:40 p.m.-11:45 p.m.

2 stops6h 05m

C$ 457

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Mon 21/9

5:40 a.m.-11:35 a.m.

1 stop6h 55m

Lambert-St Louis

Thu 24/9

6:05 a.m.-10:45 a.m.

1 stop3h 40m

C$ 465

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Fri 16/10

9:40 a.m.-7:05 p.m.

2 stops10h 25m

Lambert-St Louis

Mon 19/10

7:50 p.m.-8:25 a.m.

2 stops11h 35m

C$ 473

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Thu 15/10

6:50 a.m.-1:45 p.m.

1 stop7h 55m

Lambert-St Louis

Sun 18/10

5:50 p.m.-12:10 a.m.

1 stop5h 20m

C$ 486

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Thu 15/10

6:00 a.m.-12:15 p.m.

2 stops7h 15m

Lambert-St Louis

Mon 19/10

7:50 p.m.-8:25 a.m.

2 stops11h 35m

C$ 495

Flights are sorted by cheapest round-trip flights first.

Deals found on 19/8

Showing 1-10 of 22 resultsSorted by cheapest first
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Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, January is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 442). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 930). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to St. Louis?

Airfare is below average for this route at the moment.

Buffalo to St. Louis flights typically cost between C$ 469 and C$ 561 in September.
The cheapest round-trip price found within the last 5 days was C$ 377 on Frontier (14 Sep-21 Sep).

Related info for your journey

  • How long is the flight from Buffalo to St. Louis?

    For as low as C$ 425, Delta can have you in St. Louis from Buffalo in 5h 42m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 442). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 930). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Chesterfield

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Alternative routes for Buffalo to St. Louis

Buffalo to Kansas City flights

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How does Cheapflights help users find flights from Buffalo to St. Louis?

Cheapflights makes it easy to find Buffalo to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

Yes! Start tracking prices for Buffalo to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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