How long is the flight from Buffalo to St. Louis?

For as low as C$ 378, Southwest can have you in St. Louis from Buffalo in 5h 23m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.

In terms of precipitation, rainfall in St. Louis ranges from 56.0 - 119.0 mm per month. May is typically the wettest month, when rainfall can reach 119.0 mm. February is typically the driest time to visit St. Louis when rainfall is around 56.0 mm.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 0.0 C).

What is the cheapest time of day to fly from BUF to STL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to St. Louis as you normally would.

Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Buffalo to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

Can I find deals for business class flights from Buffalo to St. Louis?

Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 134+ Cheap Flights from Buffalo to St. Louis

Cheap flight deals from Buffalo to St. Louis

Enter your travel dates to find the best prices.

Cheapest

Best

Last-minute

One-way

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 October 2026.

Thu 12/115:30 p.m. -

1 stop7h 40m

Mon 16/116:20 a.m. -

1 stop3h 20m

Deal found 21/10C$ 335

Fri 13/119:00 a.m. -

1 stop5h 23m

Mon 16/116:00 p.m. -

1 stop4h 58m

Deal found 21/10C$ 378

Tue 24/117:20 a.m. -

1 stop4h 45m

Tue 1/122:25 p.m. -

1 stop5h 30m

Deal found 25/10C$ 380

Sat 12/126:00 a.m. -

2 stops8h 40m

Mon 14/126:20 a.m. -

1 stop3h 20m

Deal found 25/10C$ 387

Fri 11/1212:40 p.m. -

1 stop8h 20m

Mon 14/126:20 a.m. -

1 stop3h 20m

Deal found 25/10C$ 408

Fri 18/127:25 p.m. -

1 stop4h 20m

Fri 19/25:30 a.m. -

1 stop3h 50m

Deal found 22/10C$ 443

Thu 5/1112:39 p.m. -

1 stop11h 37m

Sat 7/114:26 p.m. -

1 stop24h 26m

Deal found 22/10C$ 447

Fri 25/123:55 p.m. -

1 stop7h 20m

Wed 30/123:55 p.m. -

1 stop5h 40m

Deal found 25/10C$ 455

Find flight deals from Buffalo to St. Louis

Round-trip from	C$ 335
One-way from	C$ 134
Popular in	March
Cheapest in	December
Average price	C$ 555

Southwest
12/11-16/11
2 total stops
11h 00m total
Buffalo to St. Louis

Search Deals

Frontier
7/12-31/12
1 total stop
10h 42m total
Buffalo to St. Louis

Search Deals

Highest demand for flights based on searches. 15% potential increase in price (C$ 161 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease (C$ 43 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2026

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Mon 7/12

2:30 p.m.-12:12 a.m.

1 stop10h 42m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 134

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Sat 14/11

1:10 p.m.-7:20 p.m.

1 stop7h 10m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 168

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Tue 8/12

3:00 p.m.-10:15 p.m.

2 stops8h 15m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 175

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Mon 7/12

3:55 p.m.-10:00 p.m.

2 stops7h 05m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 175

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Sat 12/12

6:00 a.m.-2:10 p.m.

2 stops9h 10m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 175

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Thu 19/11

7:05 a.m.-5:25 p.m.

2 stops11h 20m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 235

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Thu 12/11

3:05 p.m.-9:00 p.m.

2 stops6h 55m

Lambert-St Louis

Mon 16/11

6:20 a.m.-10:40 a.m.

1 stop3h 20m

C$ 342

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Fri 6/11

11:00 a.m.-7:10 p.m.

2 stops9h 10m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 370

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Fri 13/11

9:00 a.m.-1:23 p.m.

1 stop5h 23m

Lambert-St Louis

Mon 16/11

6:00 p.m.-11:58 p.m.

1 stop4h 58m

C$ 378

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Tue 3/11

5:00 p.m.-9:55 p.m.

1 stop5h 55m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 388

Flights are sorted by cheapest round-trip flights first.

Deals found on 23/10

Showing 1-10 of 22 resultsSorted by cheapest first

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.

BUF-STL

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 476). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 947). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to St. Louis?

Airfare is below average for this route at the moment.

Buffalo to St. Louis flights typically cost between C$ 445 and C$ 659 in November.
The cheapest round-trip price found within the last 5 days was C$ 335 on Southwest (12 Nov-16 Nov).

Related info for your journey

How long is the flight from Buffalo to St. Louis?
For as low as C$ 378, Southwest can have you in St. Louis from Buffalo in 5h 23m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.
Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?
Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Buffalo to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.
Can I find deals for business class flights from Buffalo to St. Louis?
Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Buffalo to St. Louis?
Currently, December is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 476). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 947). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Chesterfield

Browse thousands of different options on Cheapflights for your next trip

Alternative routes

Complete your trip

Direct flights to Missouri

Flights by cabin class

Other flight options

Popular flights

St. Louis flight routes

Alternative routes for Buffalo to St. Louis

Buffalo to Kansas City flights

Fly with Cheapflights

How does Cheapflights help users find flights from Buffalo to St. Louis?

Cheapflights makes it easy to find Buffalo to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

Yes! Start tracking prices for Buffalo to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

Cheap flights from Buffalo to St. Louis from C$ 134

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/12. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. LouisExplore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 October 2026.

Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 October 2026.

Best flights from Buffalo to St. LouisDiscover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 26 October 2026.

Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 26 October 2026.

Last-minute flights from Buffalo to St. LouisDiscover last-minute flight deals from Buffalo to St. Louis. Data last updated 26 October 2026 and is based on user searches.

Discover last-minute flight deals from Buffalo to St. Louis. Data last updated 26 October 2026 and is based on user searches.

One-way flights from Buffalo to St. LouisSearch for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated 26 October 2026.

Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated 26 October 2026.

Find flight deals from Buffalo to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.

Cheapflights Insights

What is the cheapest month to book a flight from Buffalo to St. Louis?

How much does it cost to fly round-trip from Buffalo to St. Louis?

Airfare is below average for this route at the moment.

Buffalo to St. Louis flights typically cost between C$ 445 and C$ 659 in November.The cheapest round-trip price found within the last 5 days was C$ 335 on Southwest (12 Nov-16 Nov).

Related info for your journey

How long is the flight from Buffalo to St. Louis?

Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

How can I find direct flights from Buffalo to St. Louis?

Can I find deals for business class flights from Buffalo to St. Louis?

What is the cheapest month to book a flight from Buffalo to St. Louis?

Travelling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Buffalo to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.

Direct flights to Missouri

Book a non-stop flight to one of these other cities located in Missouri.

Search flights from Buffalo to St. Louis by cabin class

Find flights from Buffalo to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Buffalo and St. Louis flights

Browse other Buffalo and St. Louis flight options. Last updated on 26 October 2026.

Popular flight searches

Check out other popular destinations found by fellow travellers in 2026

Other flights to St. Louis

Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 26 October 2026.

Fly with Cheapflights

How does Cheapflights help users find flights from Buffalo to St. Louis?

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 26 October 2026.

Best flights from Buffalo to St. Louis
Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 26 October 2026.

Last-minute flights from Buffalo to St. Louis
Discover last-minute flight deals from Buffalo to St. Louis. Data last updated 26 October 2026 and is based on user searches.

One-way flights from Buffalo to St. Louis
Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated 26 October 2026.

Buffalo to St. Louis flights typically cost between C$ 445 and C$ 659 in November.
The cheapest round-trip price found within the last 5 days was C$ 335 on Southwest (12 Nov-16 Nov).