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Cheap flights from Buffalo to St. Louis from C$ 123

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 28/9. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
21 Aug — 28 Aug1
1 adult

Cheapflights Tip: The best prices from Buffalo to Lambert-St Louis are usually found in September or July, booked 35 days in advance, depart on a Thursday or Tuesday and return on a Monday

Cheap flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 16 August 2025.

Round-trip from

C$ 327

One-way from

C$ 123

Popular in

October

Cheapest in

September

Average price

C$ 505
Delta
  • Delta
  • 13/9-15/9
  • 2 total stops
  • 10h 25m total
  • Buffalo to St. Louis
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Frontier
  • Frontier
  • 28/9
  • 1 total stop
  • 18h 21m total
  • Buffalo to St. Louis
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 0% potential price decrease (C$ 6 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 16 August 2025.

Sat 13/912:06 p.m.BUF - STL
1 stop4h 59mDelta
Mon 15/95:11 p.m.STL - BUF
1 stop5h 26mDelta
Deal found 14/8C$ 327
Tue 30/97:07 a.m.BUF - STL
1 stop4h 42mUnited Airlines
Fri 3/103:23 p.m.STL - BUF
1 stop4h 50mUnited Airlines
Deal found 15/8C$ 346
Thu 25/97:07 a.m.BUF - STL
1 stop4h 42mUnited Airlines
Sun 28/93:23 p.m.STL - BUF
1 stop4h 50mUnited Airlines
Deal found 14/8C$ 358
Fri 5/94:25 p.m.BUF - STL
2 stops7h 10mSouthwest
Sun 7/93:35 p.m.STL - BUF
1 stop7h 30mSouthwest
Deal found 14/8C$ 403
Tue 7/107:10 a.m.BUF - STL
2 stops8h 00mSouthwest
Thu 9/106:15 a.m.STL - BUF
1 stop7h 20mSouthwest
Deal found 15/8C$ 413
Sat 13/96:00 a.m.BUF - STL
2 stops9h 19mUnited Airlines
Mon 15/93:20 p.m.STL - BUF
1 stop4h 56mUnited Airlines
Deal found 14/8C$ 431
Thu 25/910:30 a.m.BUF - STL
2 stops7h 55mSouthwest
Sun 28/97:30 a.m.STL - BUF
1 stop4h 30mSouthwest
Deal found 14/8C$ 435
Tue 30/912:00 p.m.BUF - STL
1 stop4h 45mSouthwest
Fri 3/101:15 p.m.STL - BUF
2 stops8h 15mSouthwest
Deal found 15/8C$ 438
Fri 29/812:02 p.m.BUF - STL
1 stop5h 04mDelta
Sun 31/85:25 p.m.STL - BUF
1 stop4h 53mDelta
Deal found 13/8C$ 445

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 16 August 2025.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Buffalo

Fly to

St. Louis

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 13/9

12:06 p.m.-4:05 p.m.

1 stop4h 59m

Lambert-St Louis

Mon 15/9

5:11 p.m.-11:37 p.m.

1 stop5h 26m

C$ 327

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 30/9

7:07 a.m.-10:49 a.m.

1 stop4h 42m

Lambert-St Louis

Fri 3/10

3:23 p.m.-9:13 p.m.

1 stop4h 50m

C$ 346

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 7/10

6:00 a.m.-10:26 a.m.

1 stop5h 26m

Lambert-St Louis

Thu 9/10

3:59 p.m.-11:39 p.m.

1 stop6h 40m

C$ 346

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 25/9

7:07 a.m.-10:49 a.m.

1 stop4h 42m

Lambert-St Louis

Sun 28/9

3:23 p.m.-9:13 p.m.

1 stop4h 50m

C$ 358

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 30/9

12:00 p.m.-3:45 p.m.

1 stop4h 45m

Lambert-St Louis

Fri 3/10

9:50 a.m.-4:35 p.m.

1 stop5h 45m

C$ 403

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 5/9

4:25 p.m.-10:35 p.m.

2 stops7h 10m

Lambert-St Louis

Sun 7/9

3:35 p.m.-12:05 a.m.

1 stop7h 30m

C$ 403

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 7/10

7:10 a.m.-2:10 p.m.

2 stops8h 00m

Lambert-St Louis

Thu 9/10

6:15 a.m.-2:35 p.m.

1 stop7h 20m

C$ 413

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 13/9

6:00 a.m.-2:19 p.m.

2 stops9h 19m

Lambert-St Louis

Mon 15/9

3:20 p.m.-9:16 p.m.

1 stop4h 56m

C$ 431

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 25/9

10:30 a.m.-5:25 p.m.

2 stops7h 55m

Lambert-St Louis

Sun 28/9

7:30 a.m.-1:00 p.m.

1 stop4h 30m

C$ 435

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 29/8

12:02 p.m.-4:06 p.m.

1 stop5h 04m

Lambert-St Louis

Sun 31/8

5:25 p.m.-11:18 p.m.

1 stop4h 53m

C$ 445

Flights are sorted by cheapest round-trip flights first.

Deals found on 13/8

Showing 1-10 of 14 results
1
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Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

How far ahead should I book a flight from Buffalo to St. Louis?

Use this chart to determine the optimal time to book a round-trip flight from Buffalo to St. Louis. Price data was last updated on 8 August 2025.

The best time to book flights from Buffalo to St. Louis is 35 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, January is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 365). Flying from Buffalo to St. Louis in September is currently the most expensive (average of C$ 491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to STL?

Find hourly flight availability from Buffalo to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated 16 August 2025.

It’s optimal to fly from Buffalo to St. Louis in the afternoon. By choosing this option you can save up to 44% on the cost of your flight, compared to a flight at noon.

What’s the top layover airport for flights from Buffalo to St. Louis?

Share of one-stop round-trip flights from Buffalo to St. Louis chosen by Cheapflights users in the past 12 months, using the same layover each way.

Chicago (MDW) – chosen by Cheapflights users on 69% of one-stop itineraries from Buffalo to St. Louis on Cheapflights.

What’s the cheapest layover airport for flights from Buffalo to St. Louis?

Average round-trip fare for 1-stop flights from Buffalo to St. Louis, chosen by Cheapflights users in the past 12 months, with the same layover each way.

Denver (DEN) is the most affordable 1-stop option, with an average round-trip price of C$ 302.

What’s the fastest layover option from Buffalo to St. Louis?

Shortest average travel time for 1-stop one-way flights from Buffalo to St. Louis, based on itineraries clicked by Cheapflights users over the past 12 months, grouped by layover airport.

Flights via Chicago (MDW) have the shortest average one-way travel time for 1-stop routes: 4h 29m.

Which airport typically offers the quickest layover for flights from Buffalo to St. Louis?

Average layover duration for 1-stop one-way flights from Buffalo to St. Louis, chosen by Cheapflights users in the last 12 months, grouped by stopover airport.

Flights via Chicago (ORD) offer the fastest connection on this route, with an average layover time of 1h 15m.

Reviews of airlines servicing St. Louis

Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated 16 August 2025.
Check out reviews from past customers who have flown with Southwest from Buffalo to St. Louis to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,246 reviews
Check prices

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.
Southwest
8.0
Very good
4,246 reviews
Southwest
8.0
Very good
4,246 reviews
Check prices

Boarding

8.1

Crew

8.6

Overall

8.0

Food

7.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Walter,Aug 2025

OAK - SAN

Dozens of flights and I've never seen a row's beverages forgotten. I even went back and asked the attendant to check on them and nothing. I really hope it didn't have something to do with the Black mother with her kid in the row. Otherwise it was a typical Southwest flight, rapid boarding, tolerable leg room.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What is the cheapest airline to fly from Buffalo to St. Louis round-trip?

    Currently priced at C$ 409, Southwest will fly you from Buffalo to St. Louis and back. In addition to Southwest, many other airlines offer competitively priced options for your trip. You may be able to fly from Buffalo to St. Louis for 18% less than the average price by searching for this airline.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, January is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 365). Flying from Buffalo to St. Louis in September is currently the most expensive (average of C$ 491). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Chesterfield
St. Peters

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Alternative routes for Buffalo to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.
Buffalo to Kansas City flights

Top airline flying from Buffalo to St. Louis

Discover the top airline that operate flights from Buffalo to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 16 August 2025.
AirlineCheapestAverageFlexibilityOn-time
SouthwestCheapestC$ 409AverageC$ 520FlexibilityNo cancel feeOn-time63%
Search Southwest flights

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How does Cheapflights help users find flights from Buffalo to St. Louis?

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It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

Yes! Start tracking prices for Buffalo to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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