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Cheap flights from Buffalo to St. Louis from C$ 233

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 14/5. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
22 May — 29 May1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Buffalo to St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 22 April 2026.

Thu 14/511:36 a.m.
BUF
-
STL
1 stop6h 18m
Frontier
Sat 16/54:19 p.m.
STL
-
BUF
1 stop25h 27m
Frontier
Deal found 20/4C$ 233
Tue 15/97:40 p.m.
BUF
-
STL
1 stop4h 57m
Delta
Fri 18/93:42 p.m.
STL
-
BUF
1 stop7h 16m
Delta
Deal found 22/4C$ 360
Mon 11/58:00 p.m.
BUF
-
STL
1 stop3h 45m
Southwest
Wed 13/51:15 p.m.
STL
-
BUF
1 stop4h 00m
Southwest
Deal found 20/4C$ 392
Tue 15/96:00 a.m.
BUF
-
STL
2 stops7h 10m
Southwest
Fri 18/95:10 a.m.
STL
-
BUF
1 stop5h 40m
Southwest
Deal found 22/4C$ 400
Wed 3/67:00 a.m.
BUF
-
STL
1 stop6h 11m
United Airlines
Sat 6/61:13 p.m.
STL
-
BUF
1 stop6h 50m
United Airlines
Deal found 20/4C$ 441
Tue 12/51:10 p.m.
BUF
-
STL
2 stops7h 50m
Southwest
Wed 13/57:35 a.m.
STL
-
BUF
2 stops6h 00m
Southwest
Deal found 21/4C$ 466
Fri 29/52:47 p.m.
BUF
-
STL
1 stop6h 52m
Delta
Sun 31/55:20 p.m.
STL
-
BUF
1 stop5h 39m
Delta
Deal found 21/4C$ 474
Sat 9/51:57 p.m.
BUF
-
STL
1 stop5h 19m
United Airlines
Tue 12/59:21 a.m.
STL
-
BUF
1 stop6h 33m
United Airlines
Deal found 17/4C$ 501

Find flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 22 April 2026.

Round-trip from

C$ 233

Popular in

March

Cheapest in

December

Average price

C$ 537
Frontier
  • Frontier
  • 14/5-16/5
  • 2 total stops
  • 31h 45m total
  • Buffalo to St. Louis
Search Deals
Highest demand for flights based on searches. 24% potential increase in price (C$ 227 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease (C$ 44 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 22 April 2026.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 11/5

8:00 p.m.-10:45 p.m.

1 stop3h 45m

Lambert-St Louis

Wed 13/5

1:15 p.m.-6:15 p.m.

1 stop4h 00m

C$ 392

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 3/6

7:00 a.m.-12:11 p.m.

1 stop6h 11m

Lambert-St Louis

Sat 6/6

1:13 p.m.-9:03 p.m.

1 stop6h 50m

C$ 441

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 12/5

1:10 p.m.-8:00 p.m.

2 stops7h 50m

Lambert-St Louis

Wed 13/5

7:35 a.m.-2:35 p.m.

2 stops6h 00m

C$ 466

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 27/6

7:00 a.m.-10:34 a.m.

1 stop4h 34m

Lambert-St Louis

Tue 30/6

6:00 a.m.-2:25 p.m.

2 stops7h 25m

C$ 501

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 9/5

1:57 p.m.-6:16 p.m.

1 stop5h 19m

Lambert-St Louis

Tue 12/5

9:21 a.m.-4:54 p.m.

1 stop6h 33m

C$ 501

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 26/5

1:10 p.m.-8:00 p.m.

2 stops7h 50m

Lambert-St Louis

Mon 1/6

2:25 p.m.-11:20 p.m.

2 stops7h 55m

C$ 527

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 27/6

6:00 a.m.-12:55 p.m.

2 stops7h 55m

Lambert-St Louis

Tue 30/6

5:40 a.m.-2:20 p.m.

2 stops7h 40m

C$ 542

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 23/7

5:55 p.m.-12:35 a.m.

2 stops7h 40m

Lambert-St Louis

Sun 26/7

8:00 p.m.-8:10 a.m.

1 stop11h 10m

C$ 543

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Thu 20/8

6:30 a.m.-6:05 p.m.

2 stops12h 35m

Lambert-St Louis

Sun 30/8

6:00 a.m.-12:25 p.m.

1 stop5h 25m

C$ 543
Cheapest one-way

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 27/9

6:25 a.m.-9:30 a.m.

1 stop4h 05m

C$ 265

Flights are sorted by cheapest round-trip flights first.

Deals found on 20/4

Showing 1-10 of 15 resultsSorted by cheapest first
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Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, December is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 436). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 870). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to St. Louis?

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to St. Louis?

    For as low as C$ 392, Southwest can have you in St. Louis from Buffalo in 3h 45m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, December is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 436). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 870). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Chesterfield

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Alternative routes for Buffalo to St. Louis

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Buffalo to Kansas City flights

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How does Cheapflights help users find flights from Buffalo to St. Louis?

Cheapflights makes it easy to find Buffalo to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

Yes! Start tracking prices for Buffalo to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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