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Cheap flights from Buffalo to St. Louis from C$ 176

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/4. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — STL
4 Apr — 11 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Buffalo to St. Louis

Enter your travel dates to find the best prices.

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 5 March 2026.

Sat 11/41:09 p.m.
BUF
-
STL
1 stop22h 29m
Frontier
Wed 15/48:23 p.m.
STL
-
BUF
1 stop14h 17m
Frontier
Deal found 1/3C$ 331
Sun 12/48:59 p.m.
BUF
-
STL
1 stop11h 52m
Frontier
Wed 15/48:23 p.m.
STL
-
BUF
1 stop14h 17m
Frontier
Deal found 1/3C$ 339
Tue 14/46:55 p.m.
BUF
-
STL
1 stop4h 15m
Southwest
Tue 21/410:25 a.m.
STL
-
BUF
1 stop3h 55m
Southwest
Deal found 27/2C$ 351
Sat 18/46:00 a.m.
BUF
-
STL
1 stop5h 00m
Southwest
Sat 25/45:40 a.m.
STL
-
BUF
2 stops7h 35m
Southwest
Deal found 4/3C$ 358
Wed 1/45:29 a.m.
BUF
-
STL
1 stop4h 37m
American Airlines
Tue 14/44:30 p.m.
STL
-
BUF
1 stop4h 06m
American Airlines
Deal found 4/3C$ 379
Wed 8/46:02 a.m.
BUF
-
STL
1 stop7h 20m
Delta
Mon 13/45:59 p.m.
STL
-
BUF
1 stop3h 40m
Delta
Deal found 27/2C$ 381
Mon 4/54:00 p.m.
BUF
-
STL
2 stops7h 45m
Southwest
Wed 6/57:35 a.m.
STL
-
BUF
2 stops6h 00m
Southwest
Deal found 3/3C$ 395
Fri 27/35:29 p.m.
BUF
-
STL
1 stop5h 29m
United Airlines
Wed 1/410:00 a.m.
STL
-
BUF
1 stop6h 10m
United Airlines
Deal found 1/3C$ 407
Wed 1/46:42 p.m.
BUF
-
STL
1 stop6h 16m
Delta
Wed 24/65:30 p.m.
STL
-
BUF
1 stop5h 28m
Delta
Deal found 4/3C$ 418

Find flight deals from Buffalo to St. Louis

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to St. Louis (STL). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 5 March 2026.

Round-trip from

C$ 331

One-way from

C$ 176

Popular in

February

Cheapest in

September

Average price

C$ 627
Frontier
  • Frontier
  • 11/4-15/4
  • 2 total stops
  • 36h 46m total
  • Buffalo to St. Louis
Search Deals
United Airlines
  • United Airlines
  • 7/4
  • 1 total stop
  • 4h 11m total
  • Buffalo to St. Louis
Search Deals
Highest demand for flights based on searches. 14% potential increase in price (C$ 113 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease (C$ 23 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 5 March 2026.
Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 8/4

6:02 a.m.-12:22 p.m.

1 stop7h 20m

Lambert-St Louis

Mon 13/4

5:59 p.m.-10:39 p.m.

1 stop3h 40m

C$ 381

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Wed 1/4

6:42 p.m.-11:58 p.m.

1 stop6h 16m

Lambert-St Louis

Wed 24/6

5:30 p.m.-11:58 p.m.

1 stop5h 28m

C$ 418

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 11/4

12:30 p.m.-7:10 p.m.

2 stops7h 40m

Lambert-St Louis

Wed 15/4

5:35 a.m.-10:20 a.m.

1 stop3h 45m

C$ 433

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 23/5

5:26 p.m.-9:29 p.m.

1 stop5h 03m

Lambert-St Louis

Wed 27/5

6:04 p.m.-11:59 p.m.

1 stop4h 55m

C$ 467

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Tue 24/3

5:29 p.m.-10:59 p.m.

1 stop6h 30m

Lambert-St Louis

Sun 29/3

5:00 a.m.-2:17 p.m.

2 stops8h 17m

C$ 478

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Mon 6/4

5:55 p.m.-11:05 p.m.

1 stop6h 10m

Lambert-St Louis

Thu 9/4

5:40 a.m.-10:15 a.m.

1 stop3h 35m

C$ 484

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 21/6

9:00 a.m.-1:17 p.m.

1 stop5h 17m

Lambert-St Louis

Tue 30/6

5:45 p.m.-11:03 p.m.

1 stop4h 18m

C$ 500

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sat 23/5

12:30 p.m.-8:00 p.m.

2 stops8h 30m

Lambert-St Louis

Wed 27/5

5:35 a.m.-10:20 a.m.

1 stop3h 45m

C$ 502

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Fri 3/4

7:48 p.m.-11:58 p.m.

1 stop5h 10m

Lambert-St Louis

Wed 8/4

6:32 a.m.-11:44 a.m.

1 stop4h 12m

C$ 504

BuffaloSt. Louis

BUF - STL

BUFSTL

Buffalo

Sun 15/3

5:50 p.m.-8:42 p.m.

1 stop3h 52m

Lambert-St Louis

Fri 20/3

6:10 a.m.-2:19 p.m.

1 stop7h 09m

C$ 515

Flights are sorted by cheapest round-trip flights first.

Deals found on 2/3

Showing 1-10 of 17 resultsSorted by cheapest first
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Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 153). Flying from Buffalo to St. Louis in February is currently the most expensive (average of C$ 429). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to St. Louis?

    For as low as C$ 478, Delta can have you in St. Louis from Buffalo in 6h 30m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.

  • Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

    Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to St. Louis?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

  • Can I find deals for business class flights from Buffalo to St. Louis?

    Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to St. Louis?

    Currently, August is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 153). Flying from Buffalo to St. Louis in February is currently the most expensive (average of C$ 429). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near St. Louis?

Book flights to St. Louis if you plan to visit one of these locations
Chesterfield

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Alternative routes for Buffalo to St. Louis

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Buffalo to Kansas City flights

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How does Cheapflights help users find flights from Buffalo to St. Louis?

Cheapflights makes it easy to find Buffalo to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

Yes! Start tracking prices for Buffalo to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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