How long is the flight from Buffalo to St. Louis?

For as low as C$ 503, Southwest can have you in St. Louis from Buffalo in 5h 47m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.

In terms of precipitation, rainfall in St. Louis ranges from 56.0 - 119.0 mm per month. May is typically the wettest month, when rainfall can reach 119.0 mm. February is typically the driest time to visit St. Louis when rainfall is around 56.0 mm.

If weather is an important factor for your trip to St. Louis, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 27.0 C. Travellers hoping to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 0.0 C).

What is the cheapest time of day to fly from BUF to STL?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Buffalo to St. Louis as you normally would.

Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Buffalo to St. Louis?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.

Can I find deals for business class flights from Buffalo to St. Louis?

Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

C$ 199+ Cheap Flights from Buffalo to St. Louis

Cheap flight deals from Buffalo to St. Louis

Enter your travel dates to find the best prices.

Cheapest

Best

Last-minute

One-way

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2026.

Tue 20/109:06 a.m. -

1 stop5h 47m

Wed 21/106:47 a.m. -

1 stop3h 48m

Deal found 15/9C$ 317

Tue 20/104:25 p.m. -

2 stops6h 40m

Wed 21/105:45 a.m. -

1 stop6h 35m

Deal found 15/9C$ 324

Tue 17/113:55 p.m. -

2 stops7h 05m

Wed 18/116:20 a.m. -

2 stops7h 55m

Deal found 15/9C$ 331

Wed 28/104:00 p.m. -

1 stop6h 25m

Fri 30/105:25 a.m. -

1 stop4h 00m

Deal found 14/9C$ 357

Thu 12/116:00 a.m. -

2 stops7h 10m

Mon 23/115:00 p.m. -

1 stop4h 59m

Deal found 16/9C$ 363

Thu 29/106:00 a.m. -

2 stops7h 15m

Sat 31/106:10 a.m. -

1 stop3h 40m

Deal found 14/9C$ 370

Thu 12/116:00 a.m. -

2 stops10h 43m

Tue 17/119:40 a.m. -

1 stop6h 22m

Deal found 15/9C$ 455

Find flight deals from Buffalo to St. Louis

Round-trip from	C$ 317
One-way from	C$ 199
Popular in	March
Cheapest in	January
Average price	C$ 503

Delta
20/10-21/10
2 total stops
9h 35m total
Buffalo to St. Louis

Search Deals

Delta
9/10-31/12
1 total stop
6h 17m total
Buffalo to St. Louis

Search Deals

Highest demand for flights based on searches. 16% potential increase in price (C$ 170 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 5% potential price decrease (C$ 45 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in September 2026

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Fri 9/10

12:02 p.m.-5:19 p.m.

1 stop6h 17m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 199

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Tue 13/10

5:10 p.m.-10:20 p.m.

1 stop6h 10m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 241

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Sun 17/1

3:45 p.m.-7:20 p.m.

1 stop4h 35m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 278

Quickest round-trip

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Sun 18/10

5:50 a.m.-9:20 a.m.

1 stop4h 30m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 278

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Wed 28/10

4:00 p.m.-9:25 p.m.

1 stop6h 25m

Lambert-St Louis

Fri 30/10

5:25 a.m.-10:25 a.m.

1 stop4h 00m

C$ 357

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Tue 22/9

9:45 a.m.-1:55 p.m.

1 stop5h 10m

Lambert-St Louis

Wed 31/12

12:00 a.m.-1:00 a.m.

Nonstop0h 00m

C$ 372

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Thu 12/11

6:00 a.m.-3:43 p.m.

2 stops10h 43m

Lambert-St Louis

Tue 17/11

9:40 a.m.-5:02 p.m.

1 stop6h 22m

C$ 455

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Thu 19/11

3:55 p.m.-10:00 p.m.

2 stops7h 05m

Lambert-St Louis

Fri 20/11

5:45 a.m.-10:25 a.m.

1 stop3h 40m

C$ 462

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Fri 9/10

9:06 a.m.-1:53 p.m.

1 stop5h 47m

Lambert-St Louis

Sun 11/10

6:47 a.m.-11:07 a.m.

1 stop3h 20m

C$ 503

BuffaloSt. Louis

BUF Buffalo - STL Lambert-St Louis

BUFSTL

Buffalo

Thu 12/11

8:05 a.m.-4:00 p.m.

2 stops8h 55m

Lambert-St Louis

Tue 17/11

11:55 a.m.-10:00 p.m.

2 stops9h 05m

C$ 545

Flights are sorted by cheapest round-trip flights first.

Deals found on 14/9

Showing 1-10 of 17 resultsSorted by cheapest first

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.

BUF-STL

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to St. Louis

What is the cheapest month to book a flight from Buffalo to St. Louis?

Currently, January is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 448). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 943). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Buffalo to St. Louis?

Airfare is below average for this route at the moment.

Buffalo to St. Louis flights typically cost between C$ 448 and C$ 576 in October.
The cheapest round-trip price found within the last 5 days was C$ 317 on Delta (20 Oct-21 Oct).

Related info for your journey

How long is the flight from Buffalo to St. Louis?
For as low as C$ 503, Southwest can have you in St. Louis from Buffalo in 5h 47m. The distance between Buffalo and St. Louis is about 1081 km. This flight may include one or multiple stops.
Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?
Yes. In addition to deals on Buffalo to St. Louis flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Buffalo to St. Louis?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to St. Louis.
Can I find deals for business class flights from Buffalo to St. Louis?
Yes. Cheapflights offers flight deals from Buffalo to St. Louis by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Buffalo to St. Louis?
Currently, January is the cheapest month in which you can book a flight from Buffalo to St. Louis (average of C$ 448). Flying from Buffalo to St. Louis in March is currently the most expensive (average of C$ 943). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Chesterfield

Browse thousands of different options on Cheapflights for your next trip

Alternative routes

Complete your trip

Direct flights to Missouri

Flights by cabin class

Other flight options

Popular flights

St. Louis flight routes

Alternative routes for Buffalo to St. Louis

Buffalo to Kansas City flights

Fly with Cheapflights

How does Cheapflights help users find flights from Buffalo to St. Louis?

Cheapflights makes it easy to find Buffalo to St. Louis flights by helping our users search from 900+ travel sites for deals. We also provide you with filters for cabin, price, airline, airports, number of stops, and many more to narrow down that perfect flight.

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

It’s simple! Cheapflights, which is free to use for everyone, saves millions of users time and money every year by helping them find the cheapest and most suitable flights from Buffalo to St. Louis.

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Cheapflights does show flights with no change fees to all users. To see these options for flights from Buffalo to St. Louis, users can toggle the no change fees filter when performing a flight search.

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

Yes! Start tracking prices for Buffalo to St. Louis flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.

Cheap flights from Buffalo to St. Louis from C$ 199

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.

Cheap flight deals from Buffalo to St. Louis

Cheapest flights from Buffalo to St. LouisExplore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2026.

Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2026.

Best flights from Buffalo to St. LouisDiscover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 17 September 2026.

Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 17 September 2026.

Last-minute flights from Buffalo to St. LouisDiscover last-minute flight deals from Buffalo to St. Louis. Data last updated 17 September 2026 and is based on user searches.

Discover last-minute flight deals from Buffalo to St. Louis. Data last updated 17 September 2026 and is based on user searches.

One-way flights from Buffalo to St. LouisSearch for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated 17 September 2026.

Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated 17 September 2026.

Find flight deals from Buffalo to St. Louis

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Buffalo to St. Louis that are best for you.

Best time to book a flight from Buffalo to St. Louis

Have a flexible travel schedule? Discover the best time to fly to St. Louis from Buffalo with our price prediction graph.

Cheapflights Insights

What is the cheapest month to book a flight from Buffalo to St. Louis?

How much does it cost to fly round-trip from Buffalo to St. Louis?

Airfare is below average for this route at the moment.

Buffalo to St. Louis flights typically cost between C$ 448 and C$ 576 in October.The cheapest round-trip price found within the last 5 days was C$ 317 on Delta (20 Oct-21 Oct).

Related info for your journey

How long is the flight from Buffalo to St. Louis?

Can I find deals for flights from Buffalo to St. Louis that include hotel bookings?

How can I find direct flights from Buffalo to St. Louis?

Can I find deals for business class flights from Buffalo to St. Louis?

What is the cheapest month to book a flight from Buffalo to St. Louis?

Travelling to a place near St. Louis?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Buffalo to St. Louis

See prices for flight routes from nearby airports that may be better suited for you.

Complete your trip

Complete your trip to St. Louis by adding a car rental and/or hotel reservation to your travel itinerary.

Direct flights to Missouri

Book a non-stop flight to one of these other cities located in Missouri.

Search flights from Buffalo to St. Louis by cabin class

Find flights from Buffalo to St. Louis, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Buffalo and St. Louis flights

Browse other Buffalo and St. Louis flight options. Last updated on 17 September 2026.

Popular flight searches

Check out other popular destinations found by fellow travellers in 2026

Other flights to St. Louis

Explore flights to St. Louis departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on 17 September 2026.

Fly with Cheapflights

How does Cheapflights help users find flights from Buffalo to St. Louis?

Why should you use Cheapflights to find cheap flight tickets from Buffalo to St. Louis?

Can Cheapflights find flights from Buffalo to St. Louis with no change fees?

Can Cheapflights notify me if prices for flights from Buffalo to St. Louis become cheaper?

100% Free

Book with Flexibility

Travel Smart

Cheapest flights from Buffalo to St. Louis
Explore the most affordable flight options available from Buffalo to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 17 September 2026.

Best flights from Buffalo to St. Louis
Discover carefully curated flight deals from Buffalo to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated 17 September 2026.

Last-minute flights from Buffalo to St. Louis
Discover last-minute flight deals from Buffalo to St. Louis. Data last updated 17 September 2026 and is based on user searches.

One-way flights from Buffalo to St. Louis
Search for one-way flight options from Buffalo to St. Louis. Find affordable one-way fares based on user searches. Data last updated 17 September 2026.

Buffalo to St. Louis flights typically cost between C$ 448 and C$ 576 in October.
The cheapest round-trip price found within the last 5 days was C$ 317 on Delta (20 Oct-21 Oct).