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Cheap flights from Mendoza to Santiago from C$ 104

MDZ — SCL
24 Nov — 1 Dec1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Mendoza to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Mendoza to Santiago

Thu 19/115:50 p.m. -
Nonstop1h 01m
Thu 26/113:54 p.m. -
Nonstop1h 06m
Deal found 25/10C$ 164
Thu 12/115:50 p.m. -
Nonstop1h 01m
Sun 15/116:54 a.m. -
Nonstop1h 06m
Deal found 24/10C$ 167
Thu 12/115:50 p.m. -
Nonstop1h 01m
Sat 14/117:54 p.m. -
Nonstop1h 06m
Deal found 21/10C$ 171
Thu 31/125:50 p.m. -
Nonstop1h 01m
Sun 10/16:54 a.m. -
Nonstop1h 06m
Deal found 23/10C$ 206
Sun 6/127:00 p.m. -
Nonstop1h 01m
Mon 7/126:54 a.m. -
Nonstop1h 06m
Deal found 23/10C$ 211
Fri 20/117:00 p.m. -
Nonstop1h 01m
Mon 23/117:54 p.m. -
Nonstop1h 06m
Deal found 23/10C$ 228
Thu 31/125:50 p.m. -
Nonstop1h 01m
Wed 20/17:23 a.m. -
1 stop15h 03m
Deal found 21/10C$ 237
Wed 2/124:00 p.m. -
Nonstop1h 02m
Wed 9/122:05 p.m. -
Nonstop1h 05m
Deal found 23/10C$ 238

Find flight deals from Mendoza to Santiago

Round-trip from

C$ 164

One-way from

C$ 104

Popular in

July

Cheapest in

May

Average price

C$ 209
JetSMART
  • JetSMART
  • 19/11-26/11
  • Nonstop
  • 2h 07m total
  • Mendoza to Santiago
Search Deals
JetSMART
  • JetSMART
  • 16/4-31/12
  • Nonstop
  • 1h 01m total
  • Mendoza to Santiago
Search Deals
Highest demand for flights based on searches. 11% potential increase in price (C$ 35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (C$ 7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in October 2026
Search Deals

Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Mendoza to Santiago that are best for you.

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Route

Depart

Return

Price

Cheapest round-trip

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Fri 16/4

8:00 p.m.-8:01 p.m.

Nonstop1h 01m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 104

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Thu 24/12

5:50 p.m.-6:51 p.m.

Nonstop1h 01m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 105
Quickest round-trip

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Sat 21/11

9:50 p.m.-10:50 p.m.

Nonstop1h 00m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 108

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Thu 19/11

5:50 p.m.-6:51 p.m.

Nonstop1h 01m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 108

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Fri 25/12

9:00 p.m.-10:02 p.m.

Nonstop1h 02m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 155

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Thu 19/11

5:50 p.m.-6:51 p.m.

Nonstop1h 01m

Santiago Arturo Merino Benitez

Thu 26/11

3:54 p.m.-5:00 p.m.

Nonstop1h 06m

C$ 164

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Thu 12/11

5:50 p.m.-6:51 p.m.

Nonstop1h 01m

Santiago Arturo Merino Benitez

Sun 15/11

6:54 a.m.-8:00 a.m.

Nonstop1h 06m

C$ 167

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Sun 22/11

4:00 p.m.-5:01 p.m.

Nonstop1h 01m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 199

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Thu 31/12

5:50 p.m.-6:51 p.m.

Nonstop1h 01m

Santiago Arturo Merino Benitez

Mon 11/1

6:54 a.m.-8:00 a.m.

Nonstop1h 06m

C$ 206

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Sun 6/12

7:00 p.m.-8:01 p.m.

Nonstop1h 01m

Santiago Arturo Merino Benitez

Sun 13/12

6:54 a.m.-8:00 a.m.

Nonstop1h 06m

C$ 206

Flights are sorted by cheapest round-trip flights first.

Deals found on 21/10

Showing 1-10 of 18 resultsSorted by cheapest first
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Best time to book a flight from Mendoza to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Mendoza with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Mendoza to Santiago

How far ahead should I book a flight from Mendoza to Santiago?

The best time to book flights from Mendoza to Santiago is 83 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mendoza to Santiago?

Currently, May is the cheapest month in which you can book a flight from Mendoza to Santiago (average of C$ 172). Flying from Mendoza to Santiago in July is currently the most expensive (average of C$ 242). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDZ to SCL?

When flying from Mendoza to Santiago, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

How much does it cost to fly round-trip from Mendoza to Santiago?

Airfare is typical for this route at the moment.

Mendoza to Santiago flights typically cost between C$ 150 and C$ 258 in November.
The cheapest round-trip price found within the last 5 days was C$ 164 on JetSMART (19 Nov-26 Nov).

Related info for your journey

  • How popular is this Mendoza to Santiago flight route?

    This flight path from Mendoza El Plumerillo to Santiago Arturo Merino Benitez was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Mendoza to Santiago?

    For as low as C$ 164, JetSMART can have you in Santiago from Mendoza in 1h 01m. The distance from Mendoza to Santiago is about 196 km. All flights are typically direct.

  • What are the most reliable airlines from Mendoza to Santiago?

    The top 3 most reliable airlines when flying from Mendoza to Santiago are Sky Airline (93%), Iberia (91%) and Delta (89%).

  • Can I find deals for flights from Mendoza to Santiago that include hotel bookings?

    Yes. In addition to deals on Mendoza to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mendoza to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mendoza to Santiago.

  • Can I find deals for business class flights from Mendoza to Santiago?

    Yes. Cheapflights offers flight deals from Mendoza to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mendoza to Santiago?

    Currently, May is the cheapest month in which you can book a flight from Mendoza to Santiago (average of C$ 172). Flying from Mendoza to Santiago in July is currently the most expensive (average of C$ 242). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

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Viña del Mar

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