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Cheap flights from Mendoza to Santiago from C$ 105

MDZ — SCL
10 Oct — 17 Oct1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Mendoza to Santiago

Enter your travel dates to find the best prices.

Cheapest flights from Mendoza to Santiago

Thu 1/105:05 p.m. -
Nonstop1h 04m
Sun 4/106:49 a.m. -
Nonstop1h 06m
Deal found 6/9C$ 117
Thu 24/95:05 p.m. -
Nonstop1h 04m
Sun 27/96:49 a.m. -
Nonstop1h 06m
Deal found 9/9C$ 156
Fri 25/96:40 p.m. -
Nonstop1h 04m
Sun 27/96:49 a.m. -
Nonstop1h 06m
Deal found 9/9C$ 157
Thu 12/115:50 p.m. -
Nonstop1h 01m
Sat 14/117:54 p.m. -
Nonstop1h 06m
Deal found 8/9C$ 160
Fri 2/108:54 a.m. -
1 stop23h 17m
Sun 4/106:49 a.m. -
Nonstop1h 06m
Deal found 9/9C$ 272
Thu 1/105:05 p.m. -
Nonstop1h 04m
Sat 3/107:12 p.m. -
1 stop12h 57m
Deal found 5/9C$ 273
Sat 5/910:20 p.m. -
Nonstop1h 04m
Tue 8/98:04 p.m. -
Nonstop1h 06m
Deal found 5/9C$ 314
Tue 8/910:00 p.m. -
Nonstop1h 04m
Sat 12/93:09 p.m. -
Nonstop1h 06m
Deal found 8/9C$ 335
Thu 22/105:05 p.m. -
Nonstop1h 04m
Sun 25/107:12 p.m. -
1 stop27h 55m
Deal found 8/9C$ 341
Sat 19/95:05 p.m. -
Nonstop1h 04m
Sun 20/96:49 a.m. -
Nonstop1h 06m
Deal found 7/9C$ 358

Find flight deals from Mendoza to Santiago

Round-trip from

C$ 117

One-way from

C$ 105

Popular in

July

Cheapest in

October

Average price

C$ 178

Good one-way deal

C$ 344 or less
JetSMART
  • JetSMART
  • 1/10-4/10
  • Nonstop
  • 2h 10m total
  • Mendoza to Santiago
Search Deals
JetSMART
  • JetSMART
  • 16/10-31/12
  • Nonstop
  • 1h 04m total
  • Mendoza to Santiago
Search Deals
Highest demand for flights based on searches. 13% potential increase in price (C$ 41 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease (C$ 7 potential savings vs. average RT price).
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Average for round-trip flights in September 2026
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Price to beat on a one-way flight from Mendoza El Plumerillo to Santiago Arturo Merino Benitez.
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Mendoza to Santiago that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Thu 1/10

5:05 p.m.-6:09 p.m.

Nonstop1h 04m

Santiago Arturo Merino Benitez

Sun 4/10

6:49 a.m.-7:55 a.m.

Nonstop1h 06m

C$ 117
Quickest round-trip

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Sun 24/1

6:30 p.m.-7:30 p.m.

Nonstop1h 00m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 146

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Sun 22/11

7:00 p.m.-8:01 p.m.

Nonstop1h 01m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 152

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Thu 29/10

5:05 p.m.-6:09 p.m.

Nonstop1h 04m

Santiago Arturo Merino Benitez

Sun 1/11

6:54 a.m.-8:00 a.m.

Nonstop1h 06m

C$ 156

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Fri 25/9

6:40 p.m.-7:44 p.m.

Nonstop1h 04m

Santiago Arturo Merino Benitez

Sun 27/9

6:49 a.m.-7:55 a.m.

Nonstop1h 06m

C$ 157

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Fri 16/10

1:20 p.m.-6:56 p.m.

1 stop5h 36m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 204

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Sat 31/10

9:49 p.m.-8:07 a.m.

1 stop10h 18m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 205

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Thu 15/10

7:37 a.m.-8:13 a.m.

1 stop24h 36m

Santiago Arturo Merino Benitez

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 255

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Fri 2/10

8:54 a.m.-8:11 a.m.

1 stop23h 17m

Santiago Arturo Merino Benitez

Sun 4/10

6:49 a.m.-7:55 a.m.

Nonstop1h 06m

C$ 272

MendozaSantiago

MDZ Mendoza El Plumerillo - SCL Santiago Arturo Merino Benitez

MDZSCL

Mendoza El Plumerillo

Thu 1/10

5:05 p.m.-6:09 p.m.

Nonstop1h 04m

Santiago Arturo Merino Benitez

Sat 3/10

7:12 p.m.-8:09 a.m.

1 stop12h 57m

C$ 273

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 13 resultsSorted by cheapest first
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Best time to book a flight from Mendoza to Santiago

Have a flexible travel schedule? Discover the best time to fly to Santiago from Mendoza with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Mendoza to Santiago

How far ahead should I book a flight from Mendoza to Santiago?

The best time to book flights from Mendoza to Santiago is 52 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Mendoza to Santiago?

Currently, October is the cheapest month in which you can book a flight from Mendoza to Santiago (average of C$ 167). Flying from Mendoza to Santiago in July is currently the most expensive (average of C$ 239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MDZ to SCL?

When flying from Mendoza to Santiago, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 34% versus a flight in the afternoon.

How much does it cost to fly round-trip from Mendoza to Santiago?

Airfare is below average for this route at the moment.

Mendoza to Santiago flights typically cost between C$ 138 and C$ 239 in October.
The cheapest round-trip price found within the last 5 days was C$ 117 on JetSMART (1 Oct-4 Oct).

Related info for your journey

  • How popular is this Mendoza to Santiago flight route?

    This flight path from Mendoza El Plumerillo to Santiago Arturo Merino Benitez was viewed by 2 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Mendoza to Santiago?

    For as low as C$ 117, JetSMART can have you in Santiago from Mendoza in 1h 04m. The distance from Mendoza to Santiago is about 196 km. All flights are typically direct.

  • What are the most reliable airlines from Mendoza to Santiago?

    The top 3 most reliable airlines when flying from Mendoza to Santiago are Sky Airline (76%), LATAM Airlines (71%) and Delta (71%).

  • Can I find deals for flights from Mendoza to Santiago that include hotel bookings?

    Yes. In addition to deals on Mendoza to Santiago flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mendoza to Santiago?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mendoza to Santiago.

  • Can I find deals for business class flights from Mendoza to Santiago?

    Yes. Cheapflights offers flight deals from Mendoza to Santiago by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mendoza to Santiago?

    Currently, October is the cheapest month in which you can book a flight from Mendoza to Santiago (average of C$ 167). Flying from Mendoza to Santiago in July is currently the most expensive (average of C$ 239). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Travelling to a place near Santiago?

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