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Cheap flights from Santa Cruz de la Sierra to Mexico City from C$ 510

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 31/3. Fares are subject to change and may not be available on all flights or dates of travel.
VVI — MEX
22 Apr — 29 Apr1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santa Cruz de la Sierra to Mexico City

Enter your travel dates to find the best prices.

Cheapest flights from Santa Cruz de la Sierra to Mexico City
Explore the most affordable flight options available from Santa Cruz de la Sierra to Mexico City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on 23 March 2026.

Mon 1/611:47 a.m.
VVI
-
MEX
1 stop15h 13m
Copa Airlines
Sat 6/612:25 a.m.
MEX
-
VVI
1 stop20h 13m
Copa Airlines
Deal found 22/3C$ 841
Thu 26/31:14 a.m.
VVI
-
MEX
1 stop15h 16m
Copa Airlines
Fri 10/41:10 p.m.
MEX
-
VVI
1 stop12h 30m
Copa Airlines
Deal found 22/3C$ 872
Mon 4/511:47 a.m.
VVI
-
MEX
1 stop15h 13m
Copa Airlines
Fri 15/52:10 a.m.
MEX
-
VVI
1 stop18h 28m
Copa Airlines
Deal found 18/3C$ 890
Tue 14/411:48 a.m.
VVI
-
MEX
1 stop12h 17m
Copa Airlines
Sat 13/612:25 a.m.
MEX
-
VVI
1 stop20h 13m
Copa Airlines
Deal found 19/3C$ 931
Tue 7/411:48 a.m.
VVI
-
MEX
1 stop14h 27m
Copa Airlines
Sat 11/42:10 a.m.
MEX
-
VVI
1 stop18h 32m
Copa Airlines
Deal found 21/3C$ 940
Mon 23/311:54 a.m.
VVI
-
MEX
1 stop14h 21m
Copa Airlines
Mon 30/39:50 a.m.
MEX
-
VVI
1 stop11h 00m
Copa Airlines
Deal found 22/3C$ 974
Thu 19/31:14 a.m.
VVI
-
MEX
1 stop20h 06m
Copa Airlines
Sat 11/412:25 a.m.
MEX
-
VVI
1 stop20h 17m
Copa Airlines
Deal found 18/3C$ 1,006
Wed 18/31:14 a.m.
VVI
-
MEX
1 stop12h 56m
Copa Airlines
Wed 25/39:25 a.m.
MEX
-
VVI
1 stop16h 06m
Copa Airlines
Deal found 18/3C$ 1,037
Thu 4/61:12 a.m.
VVI
-
MEX
1 stop19h 53m
Copa Airlines
Mon 15/62:10 a.m.
MEX
-
VVI
1 stop18h 28m
Copa Airlines
Deal found 20/3C$ 1,052
Thu 28/51:12 a.m.
VVI
-
MEX
1 stop19h 53m
Copa Airlines
Thu 18/61:20 a.m.
MEX
-
VVI
1 stop19h 18m
Copa Airlines
Deal found 20/3C$ 1,056
Wed 10/61:12 a.m.
VVI
-
MEX
1 stop19h 53m
Copa Airlines
Sat 20/612:25 a.m.
MEX
-
VVI
1 stop20h 13m
Copa Airlines
Deal found 18/3C$ 1,140

Find flight deals from Santa Cruz de la Sierra to Mexico City

Discover tips and strategies to find the most affordable flight options for your journey from Santa Cruz de la Sierra (VVI) to Mexico City (MEX). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated 23 March 2026.

Round-trip from

C$ 841

One-way from

C$ 510

Popular in

January

Cheapest in

August

Average price

C$ 964
Copa Airlines
  • Copa Airlines
  • 1/6-6/6
  • 2 total stops
  • 35h 26m total
  • Santa Cruz de la Sierra to Mexico City
Search Deals
Copa Airlines
  • Copa Airlines
  • 31/3
  • 1 total stop
  • 15h 15m total
  • Santa Cruz de la Sierra to Mexico City
Search Deals
Highest demand for flights based on searches. 4% potential increase in price (C$ 58 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 0% potential price decrease (C$ 12 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Cruz de la Sierra to Mexico City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 629,999 searches. Data last updated 23 March 2026.
Use the filters below to find and compare flights from Santa Cruz de la Sierra to Mexico City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 1/6

11:47 a.m.-1:00 a.m.

1 stop15h 13m

Mexico City Benito Juarez

Sat 6/6

12:25 a.m.-10:38 p.m.

1 stop20h 13m

C$ 841

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Mon 4/5

11:47 a.m.-1:00 a.m.

1 stop15h 13m

Mexico City Benito Juarez

Fri 15/5

2:10 a.m.-10:38 p.m.

1 stop18h 28m

C$ 890
Quickest round-trip

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 14/4

11:48 a.m.-10:05 p.m.

1 stop12h 17m

Mexico City Benito Juarez

Sat 13/6

12:25 a.m.-10:38 p.m.

1 stop20h 13m

C$ 931

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 7/4

11:48 a.m.-12:15 a.m.

1 stop14h 27m

Mexico City Benito Juarez

Sat 11/4

2:10 a.m.-10:42 p.m.

1 stop18h 32m

C$ 940

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sat 1/8

11:47 a.m.-1:00 a.m.

1 stop15h 13m

Mexico City Benito Juarez

Thu 13/8

2:10 a.m.-10:40 p.m.

1 stop18h 30m

C$ 974

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Thu 4/6

1:12 a.m.-7:05 p.m.

1 stop19h 53m

Mexico City Benito Juarez

Mon 15/6

1:20 a.m.-10:38 p.m.

1 stop19h 18m

C$ 1,052
Cheapest one-way

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Tue 31/3

1:15 a.m.-2:30 p.m.

1 stop15h 15m

C$ 510
Quickest one-way

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Fri 27/3

3:40 a.m.-12:10 p.m.

1 stop10h 30m

C$ 543

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sat 28/3

3:35 a.m.-6:05 p.m.

1 stop16h 30m

C$ 543

Santa Cruz de la SierraMexico City

VVI - MEX

VVIMEX

Santa Cruz de la Sierra Viru Viru Intl

Sat 6/6

11:47 a.m.-10:05 p.m.

1 stop12h 18m

C$ 546

Flights are sorted by cheapest round-trip flights first.

Deals found on 22/3

Showing 1-10 of 14 resultsSorted by cheapest first
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Best time to book a flight from Santa Cruz de la Sierra to Mexico City

Have a flexible travel schedule? Discover the best time to fly to Mexico City from Santa Cruz de la Sierra with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Cruz de la Sierra to Mexico City

How far ahead should I book a flight from Santa Cruz de la Sierra to Mexico City?

Use this chart to determine the optimal time to book a round-trip flight from Santa Cruz de la Sierra to Mexico City. Price data was last updated on 13 March 2026.

The price you pay for your flight from Santa Cruz de la Sierra to Mexico City may vary depending on when you book. For the best chance of a lower fare, look to book 2 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

Currently, August is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of C$ 379). Flying from Santa Cruz de la Sierra to Mexico City in February is currently the most expensive (average of C$ 790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Santa Cruz de la Sierra to Mexico City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Santa Cruz de la Sierra to Mexico City?

    For as low as C$ 841, Copa Airlines can have you in Mexico City from Santa Cruz de la Sierra in 15h 13m. Santa Cruz de la Sierra and Mexico City are separated by a distance of 5687 km.

  • Can I find deals for flights from Santa Cruz de la Sierra to Mexico City that include hotel bookings?

    Yes. In addition to deals on Santa Cruz de la Sierra to Mexico City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Cruz de la Sierra to Mexico City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Cruz de la Sierra to Mexico City.

  • Can I find deals for business class flights from Santa Cruz de la Sierra to Mexico City?

    Yes. Cheapflights offers flight deals from Santa Cruz de la Sierra to Mexico City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Cruz de la Sierra to Mexico City?

    Currently, August is the cheapest month in which you can book a flight from Santa Cruz de la Sierra to Mexico City (average of C$ 379). Flying from Santa Cruz de la Sierra to Mexico City in February is currently the most expensive (average of C$ 790). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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When you search for this flight from Santa Cruz de la Sierra to Mexico City, Cheapflights searches on 900+ travel sites to save you time finding great flight deals online. Additionally, we offer filter features so you can choose a preferred cabin class or airline, see different price ranges, and much more so you can book the flight for you.

Why should you use Cheapflights to find cheap flight tickets from Santa Cruz de la Sierra to Mexico City?

Cheapflights helps you find that perfect flight to Mexico City from Santa Cruz de la Sierra by searching from hundreds of airlines and agencies you know and love. We are also free to use, in case you were wondering!

Can Cheapflights find flights from Santa Cruz de la Sierra to Mexico City with no change fees?

Users can book flights with no change fees policies with our dedicated filters. Book flights from Santa Cruz de la Sierra to Mexico City flexibly with Cheapflights today.

Can Cheapflights notify me if prices for flights from Santa Cruz de la Sierra to Mexico City become cheaper?

Yes, Cheapflights offers price alerts on Santa Cruz de la Sierra to Mexico City flights so you can book your travel at the perfect time. Price Alerts can be enabled by clicking the bell icon next to the flight deals above and providing your email address where you want to receive the alerts.

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