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Cheap flights from Santiago to Antofagasta from C$ 35

SCL — ANF
22 Nov — 29 Nov1
1 adult
1 adult, Economy, 0 bags

Cheap flight deals from Santiago to Antofagasta

Enter your travel dates to find the best prices.

Cheapest flights from Santiago to Antofagasta

Fri 27/118:22 p.m. -
Nonstop2h 04m
Sun 29/1110:59 p.m. -
Nonstop1h 52m
Deal found 21/10C$ 66
Sat 31/106:02 a.m. -
Nonstop2h 05m
Sun 8/119:03 p.m. -
Nonstop1h 55m
Deal found 20/10C$ 69
Mon 16/114:36 a.m. -
Nonstop2h 04m
Tue 24/117:25 a.m. -
Nonstop1h 55m
Deal found 21/10C$ 73
Fri 30/109:34 a.m. -
1 stop3h 24m
Sun 1/118:54 p.m. -
Nonstop1h 54m
Deal found 18/10C$ 74
Thu 5/113:38 p.m. -
Nonstop2h 00m
Mon 9/112:30 p.m. -
1 stop3h 03m
Deal found 20/10C$ 76
Thu 3/121:50 p.m. -
Nonstop2h 04m
Sun 6/127:51 p.m. -
Nonstop1h 55m
Deal found 22/10C$ 79
Fri 23/105:54 a.m. -
Nonstop2h 05m
Mon 26/101:03 p.m. -
Nonstop1h 57m
Deal found 20/10C$ 80
Thu 12/113:38 p.m. -
Nonstop2h 00m
Mon 16/113:23 p.m. -
Nonstop1h 54m
Deal found 22/10C$ 84
Thu 5/116:05 a.m. -
Nonstop2h 04m
Mon 9/112:57 p.m. -
Nonstop1h 55m
Deal found 22/10C$ 86
Fri 27/119:36 a.m. -
1 stop3h 24m
Sun 29/114:58 p.m. -
Nonstop1h 54m
Deal found 19/10C$ 87

Find flight deals from Santiago to Antofagasta

Round-trip from

C$ 63

One-way from

C$ 35

Popular in

February

Cheapest in

October

Average price

C$ 111
Sky Airline
  • Sky Airline
  • 1/1-8/1
  • 1 total stop
  • 9h 05m total
  • Santiago to Antofagasta
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JetSMART
  • JetSMART
  • 4/11-31/12
  • Nonstop
  • 2h 04m total
  • Santiago to Antofagasta
Search Deals
Highest demand for flights based on searches. 7% potential increase in price (C$ 14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease (C$ 4 potential savings vs. average RT price).
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Average for round-trip flights in October 2026
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Cheapflights Fare Finder

 
Use the filters below to find and compare flights from Santiago to Antofagasta that are best for you.

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Route

Depart

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Price

Cheapest round-trip

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Sat 7/11

6:05 a.m.-8:09 a.m.

Nonstop2h 04m

Antofagasta Cerro Moreno

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 35

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Sun 29/11

6:17 a.m.-8:21 a.m.

Nonstop2h 04m

Antofagasta Cerro Moreno

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 42

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Wed 13/1

10:34 a.m.-12:38 p.m.

Nonstop2h 04m

Antofagasta Cerro Moreno

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 42
Quickest round-trip

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Sun 29/11

4:06 a.m.-6:06 a.m.

Nonstop2h 00m

Antofagasta Cerro Moreno

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 50

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Thu 21/1

4:05 p.m.-7:18 p.m.

1 stop3h 13m

Antofagasta Cerro Moreno

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 50

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Tue 9/2

6:00 a.m.-8:00 a.m.

Nonstop2h 00m

Antofagasta Cerro Moreno

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 50

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Tue 5/1

3:37 p.m.-5:37 p.m.

Nonstop2h 00m

Antofagasta Cerro Moreno

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 50

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Fri 20/11

9:36 a.m.-1:00 p.m.

1 stop3h 24m

Antofagasta Cerro Moreno

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 50

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Thu 14/1

3:26 p.m.-6:32 p.m.

1 stop3h 06m

Antofagasta Cerro Moreno

Wed 31/12

12:00 a.m.-12:00 a.m.

Nonstop0h 00m

C$ 53

SantiagoAntofagasta

SCL Santiago Arturo Merino Benitez - ANF Antofagasta Cerro Moreno

SCLANF

Santiago Arturo Merino Benitez

Fri 6/11

8:22 p.m.-10:26 p.m.

Nonstop2h 04m

Antofagasta Cerro Moreno

Sun 8/11

9:03 p.m.-10:58 p.m.

Nonstop1h 55m

C$ 66

Flights are sorted by cheapest round-trip flights first.

Deals found on 20/10

Showing 1-10 of 18 resultsSorted by cheapest first
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Best time to book a flight from Santiago to Antofagasta

Have a flexible travel schedule? Discover the best time to fly to Antofagasta from Santiago with our price prediction graph.
Estimated round-trip price

Cheapflights Insights

Everything you need to know about your flight from Santiago to Antofagasta

How far ahead should I book a flight from Santiago to Antofagasta?

Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from Santiago to Antofagasta. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Santiago to Antofagasta?

Currently, October is the cheapest month in which you can book a flight from Santiago to Antofagasta (average of C$ 111). Flying from Santiago to Antofagasta in February is currently the most expensive (average of C$ 156). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SCL to ANF?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Santiago to Antofagasta as you normally would.

How much does it cost to fly round-trip from Santiago to Antofagasta?

Airfare is below average for this route at the moment.

Santiago to Antofagasta flights typically cost between C$ 78 and C$ 201 in January.
The cheapest round-trip price found within the last 5 days was C$ 63 on Sky Airline (1 Jan-8 Jan).

Related info for your journey

  • How popular is this Santiago to Antofagasta flight route?

    The Santiago Arturo Merino Benitez to Antofagasta Cerro Moreno flight path was viewed by 1 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Santiago to Antofagasta?

    A quick flight from Santiago to Antofagasta can take about 2h 04m. JetSMART provides one of the quickest options available for as low as C$ 66. The distance between Santiago and Antofagasta is about 1106 km. When browsing for deals, the options you’ll see will be for both direct flights and flights with stops.

  • What are the most reliable airlines from Santiago to Antofagasta?

    Before booking your flight to Antofagasta from Santiago, check out the most reliable airlines to get you to your destination on time: Qantas Airways (93%), Iberia (93%), Delta( 88%).

  • Can I find deals for flights from Santiago to Antofagasta that include hotel bookings?

    Yes. In addition to deals on Santiago to Antofagasta flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santiago to Antofagasta?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santiago to Antofagasta.

  • Can I find deals for business class flights from Santiago to Antofagasta?

    Yes. Cheapflights offers flight deals from Santiago to Antofagasta by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santiago to Antofagasta?

    Currently, October is the cheapest month in which you can book a flight from Santiago to Antofagasta (average of C$ 111). Flying from Santiago to Antofagasta in February is currently the most expensive (average of C$ 156). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Yes! Start tracking prices for Santiago to Antofagasta flights today and get alerted whenever prices for these flights change. To access this feature, click the bell icon next to the flight deals above, which will prompt you for a valid email address to receive your alerts.

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